Keywords: پپتید آمیلیید ب; AD; Alzheimer's disease; Aβ; β-amyloid peptide; NFTs; neurofibrillary tangles; EOAD; early-onset AD; LOAD; late-onset AD; OMOT; One-molecule-one-target; ROS; reactive oxygen species; CDMT; Combination-drugs-multi-targets; BBB; blood brain barrier; DDT;
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Keywords: پپتید آمیلیید ب; Aβ; amyloid-β peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; ATP; adenosine triphosphate; BBB; blood-brain barrier; CNS; central nervous system; ECM; extracellular matrix; Hsp; heat shock protein; IFN; interferon; IκB; NF-κB inhib
Keywords: پپتید آمیلیید ب; Aβ; amyloid-β peptide; AD; Alzheimer's disease; ASBA; 2-amino-5-sulfobenzoic acid; BDC; 1-4-benzendicarboxylate; BHC; mellitic acid; BIMB; 1,4-bis(1H-imidazol-1-yl)butane; 2,2Ë-Bipy; 2,2â²-Bipyridine; 4,4Ë-Bipy; 4,4â²-Bipyridine; BPTC; 3,3â²,5,
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Melatonin; βAPP; Amyloid-β peptide; Neurotoxicity; Therapeutic;
Keywords: پپتید آمیلیید ب; Alzheimer disease; Amyloid-β peptide; Membrane protein; Protease; Secretase; Degradation;
Keywords: پپتید آمیلیید ب; Tau phosphorylation; Tau pathology; Alzheimer's disease; Obesity; Exercise; Caloric restriction; Western diet; Tauopathies; AD; Alzheimer's disease; T2DM; type 2 diabetes; Aβ; amyloid-β peptide; CTL; control; WD; Western diet; ex; voluntary exercise; CR
Keywords: پپتید آمیلیید ب; Alzheimer disease; Amyloid-β peptide; Atherosclerosis; High-frequency ultrasound; Pulse wave velocity;
Keywords: پپتید آمیلیید ب; Aging; Docosahexaenoic acid; Lipid rafts; Membrane remodeling; Neuronal membrane; Omega3 polyunsaturated fatty acids; Aβ; amyloid-β peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; CNS; central nervous system; DHA; docosahexaenoic acid;
Keywords: پپتید آمیلیید ب; Mild Alzheimer's disease; Solanezumab; Clinical trial; Phase 3; Cognition; Function; Safety; Monoclonal antibody; EXPEDITION; Target engagement; Amyloid-β peptide; LZAM; LZAN;
Keywords: پپتید آمیلیید ب; Aβ; amyloid-β peptide; AD; Alzheimer's disease; AFM; atomic force microscopy; ALS; amyotrophic lateral sclerosis; dpi; days post injection; HuPrP; human PrPC; HX-MS; hydrogen/deuterium exchange measured using mass spectrometry; LBs; Lewy bodies; PD; Par
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Amyloid-β peptide; The neurovascular unit; Pinocembrin; The receptor for advanced glycation end products;
Keywords: پپتید آمیلیید ب; AD; Alzheimer's disease; APP; amyloid precursor protein; PS1; presenilin-1; Aβ; amyloid-β peptide; GFP; green fluorescent protein; WT; wild type; LC/MS; liquid chromatography/mass spectrometry; PC; phosphatidylcholine; PE; phosphatidylethanolamine; PS;
Keywords: پپتید آمیلیید ب; Aβ1-42; amyloid-β peptide; AD; Alzheimer's disease; anti-IGFBP7; anti-insulin-like growth factor antibody; BAM10; amyloid-β monoclonal antibody clone; BBB; blood-brain barrier; BRAIN; brain research through advancing innovative neurotechnologies; Cd2
Keywords: پپتید آمیلیید ب; Antioxidant gene therapy; Brain ischemia; Neurodegenerative disorders; Oxidative stress; Virus-mediated gene delivery; ROS; ÎΨm; mitochondrial membrane potential; 3-NP; 3-nitropropionic acid; 6-OHDA; 6-hydroxydopamine; AADC; aromatic-l-amino decarboxyla
Nitration of amyloid-β peptide (1-42) as a protective mechanism for the amyloid-β peptide (1-42) against copper ion toxicity
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Amyloid-β peptide; Copper ion; Tyrosine nitration;
Development and validation of an UHPLC-ESI-QTOF-MS method for quantification of the highly hydrophilic amyloid-β oligomer eliminating all-D-enantiomeric peptide RD2 in mouse plasma
Keywords: پپتید آمیلیید ب; UHPLC-ESI-QTOF-MS; Mouse plasma; D-peptide; Amyloid-β peptide; Therapeutic compound; Alzheimer's disease;
Simulating the γ-secretase enzyme: Recent advances and future directions
Keywords: پپتید آمیلیید ب; γ-secretase; Presenilin; Amyloid-β peptide; Alzheimer's disease; Molecular dynamics; Computational approaches;
Metal-involved theranostics: An emerging strategy for fighting Alzheimer's disease
Keywords: پپتید آمیلیید ب; 3,4Apy; 3,4-diaminopyridine; 4Apy; 4-aminopyridine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AFM; atomic force microscopy; APP; amyloid precursor protein; Aβ; amyloid-β peptide; BBB; blood brain barrier; bpy; 2,2-bipyridine; BSA; bovine se
Human amyloid β peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegans
Keywords: پپتید آمیلیید ب; AD; Alzheimer's disease; Aβ; amyloid-β peptide; PTCH1; patched homolog 1; TBC1D16; the Rab GTPase activating protein; WDFY3; the WD repeat and FYVE domain-containing protein 3; ARFGEF2; ADP-ribosylation factor guanine nucleotide exchange factor 2; EBF1;
Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance
Keywords: پپتید آمیلیید ب; AD; Alzheimer's disease; AFM; atomic force microscopy; APP; amyloid precursor protein; Aβ; amyloid-β peptide; DHA; dihydro ascorbic acid; EPR; electron paramagnetic resonance; FAD; familial Alzheimer's disease; hAβ, hIAPP; human peptides; IAPP; isl
Competitive homo- and hetero- self-assembly of amyloid-β 1-42 and 1-40 in the early stage of fibrillation
Keywords: پپتید آمیلیید ب; AD; Alzheimer's disease; Aβ; amyloid-β peptide; Aβ40; amyloid-β peptide (1-40); Aβ42; amyloid β peptide (1-42); APP; amyloid precursor protein; Ala; alanine; ATD; arrival time distribution; CCS; collision cross section; DTIMS; drift tube ion m
Morroniside prevents H2O2 or Aβ1-42-induced apoptosis via attenuating JNK and p38 MAPK phosphorylation
Keywords: پپتید آمیلیید ب; Morroniside; Amyloid-β peptide; Oxidative stress; Mitogen-activated protein kinase; Alzheimer's disease;
NBD-BPEA regulates Zn2+- or Cu2+-induced Aβ40 aggregation and cytotoxicity
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Amyloid-β peptide; Metal; Chelators;
Protective effects of hydroxytyrosol against α-synuclein toxicity on PC12â¯cells and fibril formation
Keywords: پپتید آمیلیید ب; AD; Alzheimer's Disease; Aβ; amyloid-β peptide; BBB; Blood Brain Barrier; DMEM; Dulbecco's Modified Eagle's Medium; DMSO; dimethyl sulfoxide; EFSA; European Food Safety Authority; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide; NQO1;
Physiologically-relevant levels of sphingomyelin, but not GM1, induces a β-sheet-rich structure in the amyloid-β(1-42) monomer
Keywords: پپتید آمیلیید ب; Peptide-membrane interactions; Sphingomyelin; Lipid rafts; Amyloid-β peptide; Molecular dynamics; Membrane simulations; GM1; Gangliosides; Peptide-ganglioside interactions;
Validation of ethnopharmacology of ayurvedic sarasvata ghrita and comparative evaluation of its neuroprotective effect with modern alcoholic and lipid based extracts in β-amyloid induced memory impairment
Keywords: پپتید آمیلیید ب; AD; Alzheimer's Disease; Aβ25-35; Beta amyloid 25-35 protein; HPLC; high performance liquid chromatography; SG; Sarasvata ghrita; EE; Ethanolic extract; LE; Lipid based extract; MWM; Morris water maze; RAM; Radial arm maze; BDNF; Brain derived neurot
O-GlcNAcylation and neuronal energy status: Implications for Alzheimer's disease
Keywords: پپتید آمیلیید ب; 3xTg-AD; triple transgenic mouse model of Alzheimer's disease; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; Asn; asparagine residue; ATP5A; ATP synthase subunit α; Aβ; amyloid-β peptide; AβPP; amyloid-β precursor protein; ER; endo
The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process
Keywords: پپتید آمیلیید ب; Amyloid-β peptide; Fibrils; Atomic Force Microscopy; Circular Dichroism; Metal ions; Inhibitors;
The SNK and SPAR signaling pathway changes in hippocampal neurons treated with amyloid-beta peptide in vitro
Keywords: پپتید آمیلیید ب; Dendritic spine; Amyloid-β peptide; Serum-inducible kinase; Spine-associated Rap guanosine triphosphatase-activating protein;
Original articleTrehalose induced conformational changes in the amyloid-β peptide
Keywords: پپتید آمیلیید ب; Amyloid-β peptide; Trehalose; Unstructured; Induced folding;
Prophylactic active immunization with a novel epitope vaccine improves cognitive ability by decreasing amyloid plaques and neuroinflammation in APP/PS1 transgenic mice
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Amyloid-β peptide; Neuroinflammation; Gliosis; Epitope vaccine;
ReviewAmylin and its G-protein-coupled receptor: A probable pathological process and drug target for Alzheimer's disease
Keywords: پپتید آمیلیید ب; AD; Alzheimer's disease; AmR; amylin receptor; Aβ; amyloid-β peptide; BBB; blood-brain barrier; CGRP; calcitonin gene-related peptide; CTR; calcitonin receptor; GPCR; G-protein-coupled receptor; IDE; insulin-degrading enzyme; LRP1; lipoprotein recep
Research paperEffects of phenothiazine-structured compounds on APP processing in Alzheimer's disease cellular model
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Amyloid-β peptide; Cholinesterase inhibitor; Phenothiazine; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; ACh; acetylcholine; AChE; acetylcholinesterase; BACE1; β-site APP-cleaving enzyme 1; BChE; butyryl
Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's disease
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Diabetes mellitus; ob/ob mice; Tau hyperphosphorylation, hippocampus; Kinase; Phosphatase; Hypothermia; Temperature; Thermoregulation; Leptin; Caffeine; T2DM; type 2 diabetes; AD; Alzheimer's disease; Aβ; amyloid-β peptide; ITT; Ins
Regular articleOligomeric amyloid-β peptide disrupts olfactory information output by impairment of local inhibitory circuits in rat olfactory bulb
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Amyloid-β peptide; Gamma-aminobutyric acid; Inhibitory neuronal circuit; Mitral cell; Olfactory bulb;
CD36 Deficiency Suppresses Epileptic Seizures
Keywords: پپتید آمیلیید ب; AA; arachidonic acid; ACSF; artificial cerebral spinal fluid; AD; Alzheimer's disease; ANOVA; analysis of variance; APs; action potentials; Aβ; amyloid-β peptide; CD36; cluster of differentiation 36; CNS; central nervous system; HEPS; (4-(2-hydroxyeth
Detection of Aβ oligomers based on magnetic-field-assisted separation of aptamer-functionalized Fe3O4 magnetic nanoparticles and BaYF5:Yb,Er nanoparticles as upconversion fluorescence labels
Keywords: پپتید آمیلیید ب; Aβ; amyloid-β peptide; Aβo; Aβ oligomers; AD; Alzheimer's disease; MNPs; magnetic nanoparticles; UCNPs; upconversion nanoparticles; NPs; nanoparticles; CSF; cerebrospinal fluid; SELEX; Systematic Evolution of Ligands by EXponential enrichment; UV-vi
Structural studies of amyloid-β peptides: Unlocking the mechanism of aggregation and the associated toxicity
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Amyloid-β peptide; Amyloid structure; Aggregation mechanism; Neurotoxicity;
Analysis of ribosomal protein S6 baseline phosphorylation and effect of tau pathology in the murine brain and human hippocampus
Keywords: پپتید آمیلیید ب; AD; Alzheimer's disease; Aβ; amyloid-β peptide; FTDP-17; frontotemporal dementia and Parkinsonism linked to chromosome 17; GVD; granulovacuolar degeneration; mTOR; mammalian target of rapamycin; NFTs; neurofibrillary tangles; p70S6K; S6 kinases; PI3K;
Immunosensor for diagnosis of Alzheimer disease using amyloid-β 1-40 peptide and silk fibroin thin films
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Immunosensor; Silk fibroin; Layer-by-layer; Amyloid-β peptide;
Active immunization with the peptide epitope vaccine Aβ3-10-KLH induces a Th2-polarized anti-Aβ antibody response and decreases amyloid plaques in APP/PS1 transgenic mice
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Amyloid-β peptide; Epitope vaccine; Carrier protein; Multiple-antigen peptides;
ESI-IMS-MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules
Keywords: پپتید آمیلیید ب; Aβ; amyloid-β peptide; Aβ40; amyloid-β peptide residues 1-40; AD; Alzheimer's disease; ADH; alcohol dehydrogenase; AFM; atomic force microscopy; CCS; collision-cross sectional area; Cl-NQTrp; chloronaphthoquinine-tryptophan; CsI; caesium iodide; D
New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity
Keywords: پپتید آمیلیید ب; Alzheimer's disease; Glucocorticoid receptors; HPA axis; Amyloid-β peptide; Hippocampus; Selective GR modulator; Aβ25-35 peptide; Rat;
A highly sensitive resonance light scattering probe for Alzheimer׳s amyloid-β peptide based on Fe3O4@Au composites
Keywords: پپتید آمیلیید ب; Amyloid-β peptide; Fe3O4@Au composites; Core/shell; Resonance light scattering;
Synthetic ceramide analogues increase amyloid-β 42 production by modulating γ-secretase activity
Keywords: پپتید آمیلیید ب; AD; Alzheimer disease; FAD; familial AD; Aβ; amyloid-β peptide; APP; amyloid precursor protein; BACE1; β-site APP cleaving enzyme 1; PDMP; dl-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol; DMAPP; (1S,2R-d-erythro-2-N-myristoylamino)-1-phenyl-1
ER and Golgi stresses increase ER-Golgi SNARE Syntaxin5: Implications for organelle stress and βAPP processing
Keywords: پپتید آمیلیید ب; Aβ peptide; amyloid-β peptide; AD; Alzheimer's disease; BFA; brefeldin A; βAPP; β-amyloid precursor protein; DIV; day in vitro; ELISA; enzyme linked immunosorbent assay; ER; endoplasmic reticulum; SERCA; sarco/endoplasmic reticulum Ca2+-ATPase; siRNA;
Icariin decreases both APP and Aβ levels and increases neurogenesis in the brain of Tg2576 mice
Keywords: پپتید آمیلیید ب; AD; Alzheimer's disease; Aβ; amyloid-β peptide; ANOVA; one-way analysis of variance; APP; amyloid-β precursor protein; BCA; bicinchoninic acid; BrdU; 5-bromo-2-deoxyuridine; DG; dentate gyrus; ELISA; enzyme-linked immunosorbent assay; NeuN; neuron-sp
Tyrosine Based Electrochemical Analysis of Amyloid-β Fragment (1-16) Binding to Metal(II) Ions
Keywords: پپتید آمیلیید ب; Alzheimer's disease; amyloid-β peptide; tyrosine; copper(II) ion; zinc(II) ion;
Europium as an inhibitor of Amyloid-β(1-42) induced membrane permeation
Keywords: پپتید آمیلیید ب; Amyloid-β Peptide; Europium; GM1 ganglioside; Permeation inhibition; Alzheimer's disease; Protein misfolding;
Inhibition of PMCA activity by tau as a function of aging and Alzheimer's neuropathology
Keywords: پپتید آمیلیید ب; AD; Alzheimer´s disease; Aβ; amyloid-β peptide; MV; membrane vesicles; NFTs; neurofibrillary tangles; PMCA; plasma membrane Ca2+-ATPase; SERCA; sarco(endo)plasmic reticulum Ca2+-ATPase; SPCA; secretory pathway Ca2+-ATPase; Tau; Calcium; PMCA; Aging; Al