Keywords: APC; antigen presenting cell; APOBEC; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like; BRCA1/2; breast cancer 1/2; BCSS; breast cancer specific survival; B2M; β-2-microglobulin; CAF; cancer associated fibroblast; CCL; chemokine ligand; CD
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Keywords: Esophageal Cancer; Genomics; Epigenomics; ADAR; adenosine deaminases acting on RNA; APOBEC; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; BCH; basal cell hyperplasia; CIS; carcinoma in situ; CNA; copy number alteration; ESCC; esophagea
Keywords: Follicular fluid; Fallopian tube; Apobec; Ovulation; DNA damage; Ovarian cancer;
Keywords: Esophagus; Sequencing; Carcinogenesis; Driver Mutation; APOBEC; apolipoprotein B messenger RNA editing enzyme, catalytic polypeptide-like; CNA; copy number alteration; EAC; esophageal adenocarcinoma; ESCC; esophageal squamous cell carcinoma; ESSH; esophag
Keywords: Esophagus; Genome-wide Association Study; Mutational Signature; Chromothripsis; Cytosponge; APOBEC; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like; BE; Barrett's esophagus; BEACON; Barrett's and Esophageal Adenocarcinoma Consortium; B
Keywords: AIDS; acquired immune deficiency syndrome; ALV; avian leukosis virus; AMV; avian myeloblastosis virus; APOBEC; apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like; ASLV; avian sarcoma leukosis virus; AZT; 3â² -azido-3â² -deoxythymidine; BIV;
Keywords: AID; activation induced cytidine deaminase a APOBEC family member of DNA/RNA C-to-U editors and viral/transposon restriction factors; AP; apurinic or apyrimidinic site as a result of Base Excision Repair (BER); APE; AP endonuclease causes cleavage of the
Keywords: Epigenetic dynamics; Immune system; Autoimmune diseases; DNA methylation; Histone modifications; DNMT; DNA methyltransferase; TET; ten-eleven translocation; AID/AICDA; activation-induced cytidine deaminase; APOBEC; Apolipoprotein B mRNA editing enzyme; BE
Keywords: AIM2; absent in melanoma 2; AP-1; activating protein-1; APOBEC; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; AZT; azidothymidine; CCCR5; C-C chemokine receptor type 5; CDK1; cyclin-dependent kinase 1; CXCR4; C-X-C chemokine receptor t
APOBEC and ADAR deaminases may cause many single nucleotide polymorphisms curated in the OMIM database
Keywords: A>>T; SNPs or mutations of A exceed SNPs or mutations of T; ADAR; Adenosine Deaminase that acts on RNA. There are two main isoformsADAR1 and ADAR2 that have similar WA targeting specificity; AID; activation induced cytidine deaminase, an APOBEC family mem
Mutational game changer: Chromothripsis and its emerging relevance to cancer
Keywords: SAC; spindle assembly checkpoint; APOBEC; apolipoprotein B mRNA-editing catalytic subunit; SNP; single-nucleotide polymorphism; array-CGH; comparative genomic hybridization; CLTP; chromothripsis-like pattern; SKY; spectral karyotyping; FISH; fluorescent i
Molecular cloning and characterization of APOBEC3 family in tree shrew
Keywords: 3DPCR; differential DNA denaturation PCR; A; adenosine; AID; activation-induced cytidine deaminase; APOBEC; apolipoprotein B mRNA-editing enzyme catalytic polypeptide proteins; APOBEC3; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 pro
Transposable element dysregulation in systemic lupus erythematosus and regulation by histone conformation and Hsp90
Keywords: Adar; RNaseL; Lupus; Heat shock; Epigenetics; Histone deacetylase inhibitor; 17-AAG; 17-Demethoxy-17-(2-propenylamino) geldanamycin; APOBEC; Apolipoprotein B mRNA Editing Enzyme Catalytic Polypeptide-Like; ERV; Endogenous retrovirus; H3K4me3; Histone 3, l
Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism
Keywords: TLR7; GS-9620; Hepatitis B virus; Interferon-alpha; cccDNA; Interferon-stimulated gene; MHC; Immunoproteasome; APOBEC; Smc5/6;
Type I interferon and HIV: Subtle balance between antiviral activity, immunopathogenesis and the microbiome
Keywords: IFN; interferon; ISGs; IFNstimulated genes; HCV; hepatitis C virus; IL-10; interleukin-10; PDL-1; programmed death-ligand 1; LCMV; lymphocytic choriomeningitis virus; IFNAR; IFNA receptor; IRFs; IFN regulatory factors; pDCs; plasmacytoid dendritic cells;
HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon
Keywords: Coinfection; Interferon-stimulated Gene; PRR; RIG-I; APOBEC; apolipoprotein B mRNA editing enzyme catalytic subunit; cccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; circDNA; circular DNA; GFP-IRF3; green fluorescent protein-interferon
Multi-modality analysis supports APOBEC as a major source of mutations in head and neck squamous cell carcinoma
Keywords: APOBEC; Head and neck squamous cell carcinoma; Human papilloma virus; Mutational signature;
Molecular characterization of AID-mediated reduction of hepatitis B virus transcripts
Keywords: HBV; hepatitis B virus; rcDNA; relaxed circular DNA; pgRNA; pregenomic RNA; AID; activation-induced cytidine deaminase; WT; wild type; NES; nuclear export signal; APOBEC; Apolipoprotein B100 mRNA editing enzyme; Ig; Immunoglobulin; CS; class switch; HBV;
APOBEC2 negatively regulates myoblast differentiation in muscle regeneration
Keywords: APOBEC; apoB mRNA editing enzyme catalytic polypeptide-like; CTX; cardiotoxin; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; HS; horse serum; MEF2C; myocyte enhancer factor 2C; MyHC; myosin heavy chain; APOBEC2; Muscle regeneratio
APOBEC: From mutator to editor
Keywords: Base editor; Base editing; APOBEC; CRISPR/Cas9; Mutagenesis;
Structural components of chemosensory protein mutations in the silkworm moth, Bombyx mori
Keywords: Insects; Lepidoptera; Cysteine; Glycine; α-helix; Protein evolution; A; adenine; ADAR; adenosine deaminase acting on RNA; APOB; apolipoprotein B; APOBEC; apolipoprotein B editing catalytic subunit; Bmor; Bombyx mori; C; cytosine; cDNA; complementary DNA;
Evidence for APOBEC3B mRNA and protein expression in oral squamous cell carcinomas
Keywords: APOBEC; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3; OSCC; oral squamous cell carcinoma; HNSCC; head and neck squamous cell carcinoma; SNP; single nucleotide polymorphism; FFPE; formalin-fixed, paraffin-embedded; APOBEC3B; Head and n
Active DNA demethylation by DNA repair: Facts and uncertainties
Keywords: 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5hmU; 5-hydroxymethyluracil; 5fC; 5-formylcytosine; 5caC; 5-carboxycytosine; AID; activation-induced deaminase; APE1; apurinic/apyrimidinic endonuclease 1; APOBEC; apolipoprotein B mRNA editing enzyme,
DNA Editing by APOBECs: A Genomic Preserver and Transformer
Keywords: AID; APOBEC; retrotransposons; DNA editing; C-to-U editing; genome evolution
Structural and functional assessment of APOBEC3G macromolecular complexes
Keywords: aa; amino acid; APOBEC; Apolipoprotein B Editing Catalytic Subunit-like; CD; cytidine deaminase domain; RNP; ribonucleoprotein particle; ZDD; zinc-dependent deaminase domain; EMSA; electrophoretic mobility shift assays; FA; fluorescence anisotropy; MS; ma
The APOBEC3B deletion polymorphism is associated with prevalence of hepatitis B virus, hepatitis C virus, Torque Teno virus, and Toxoplasma gondii co-infection among HIV-infected individuals
Keywords: APOBEC; HIV; HBV; HCV; TTV; Toxoplasma gondii;
Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling
Keywords: 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formylcytosine; 5caC; 5-carboxylcytosine; 5hmU; 5-hydroxymethyluracil; BER; base excision repair; TET; Ten-eleven translocation; TDG; thymine DNA glycosylase; βGT; β-glucosyltransferase; AID;
Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives
Keywords: C; Cytosine; DNMT; DNA methyl transferase; BER; Base Excision Repair; NER; Nucleotide Excision Repair; TET; Ten Eleven Translocation protein; 5mC; 5methylcytosine; 5hmC; 5-hydroxymethylcytosine; 5fC; 5-formylcytosine; 5caC; 5-carboxylcytosine; ESC; Embryo
APOBEC3 genes: retroviral restriction factors to cancer drivers
Keywords: APOBEC; cancer; mutagenesis
Estimating the fraction of progeny virions that must incorporate APOBEC3G for suppression of productive HIV-1 infection
Keywords: APOBEC; Vif; Hypermutation; Extinction threshold; Mathematical model; Stochastic simulations; Viral dynamics;
Viral infection-oxidative stress/DNA damage-aberrant DNA methylation: separate or interrelated events responsible for genetic instability and childhood ALL development?
Keywords: AID; activation-induced cytidine deaminase; ALL; acute lymphoblastic leukemia; APOBEC; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like deaminase BER, base excision repair; 5-hmCyt; 5-hydroxymethylcytosine; 5-hmUra; 5-hydroxymethyluracil; 5
The emerging role of RNA and DNA editing in cancer
Keywords: RNA editing; ADAR; APOBEC; Cancer;
The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability
Keywords: R-loops; Genome instability; Double-strand breaks; G-quadruplex; Topoisomerase; THO/TREX complex; THSC/TREX-2; ASF splicing factor; mRNP biogenesis; RNA processing factors; RNase H; RNA:DNA helicases; Senataxin; Activation-induced deaminase (AID); APOBEC
TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine
Keywords: α-KG; α-ketoglutarate; AML; acute myeloid leukemia; APOBEC; apolipoprotein B mRNA-editing enzyme complex; ARP; aldehyde reactive probe; β-GT; β-glucosyl transferase; 5-caC; 5-carboxylcytosine; 5-cadCyd; 5-carboxyl-2â²-deoxycytidine; C; cytosine; C5-M
HIV infection en route to endogenization: two cases
Keywords: APOBEC; cure; DNA integration; endogenization; endogenous retrovirus; human immunodeficiency virus; stop codon; tryptophan; Vif;
Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus
Keywords: AID; activation-induced cytidine deaminase; APOBEC; apolipoprotein B mRNA-editing enzyme catalytic subunit; UNG; uracil-DNA glycosylase; DHBV; duck hepatitis B virus; cccDNA; covalently closed circular DNA; 3D-PCR; differential denaturation DNA PCR; AID;
Atomic force microscopy studies of APOBEC3G oligomerization and dynamics
Keywords: APOBEC; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; A3G; APOBEC3G; AFM; atomic force microscopy; ssDNA; single-stranded DNA; APS-mica; aminopropyl silatrane treated mica; APOBEC3G; Single-stranded DNA binding proteins; Site search me
microRNA control of interferons and interferon induced anti-viral activity
Keywords: ADAR; adenosine deaminase acting on RNA; APOBEC; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like; IFN; interferon; IFN-R; interferon receptor; IRF; interferon regulatory factor; JAK; janus kinase; miR or miRNA; microRNA; NO; nitric oxide;
The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis
Keywords: Abasic site; Translesion DNA synthesis; APOBEC; Single-strand DNA; Deoxycytidyltransferase
IL-2 and GM-CSF are regulated by DNA demethylation during activation of T cells, B cells and macrophages
Keywords: MeDIP; immunoprecipitation of methylated DNA; DNMT; DNA methyltransferase; AID; activation-induced deaminase; APOBEC; apolipoprotein B-editing catalytic; Gadd45; growth arrest and DNA-damage-inducible 45; Tet; ten-eleven-translocation proteins; DNA demeth
Functions and regulation of the APOBEC family of proteins
Keywords: APOBEC; DNA deaminase; Mutation; Regulation; RNA editing;
Direct evidence that RNA inhibits APOBEC3G ssDNA cytidine deaminase activity
Keywords: APOBEC; Deaminase; Ribonucleotprotein; RNA; ssDNA; HIV;
G to A hypermutation of TT virus
Keywords: HBV, hepatitis B virus; TTV, TT virus; APOBEC3, apolipoprotein B editing component 3; IFN, interferonTTV; HBV; Hypermutation; APOBEC; 3D-PCR
APOBEC1 and APOBEC3 Cytidine Deaminases as Restriction Factors for Hepadnaviral Genomes in Non-Humans In Vivo
Keywords: HBV, hepatitis B virus; HIV, human immunodeficiency virus; ssDNA, single-stranded DNA; IFN, interferon; WHV, woodchuck hepatitis virus; DHV, duck hepatitis virus; GE, genome equivalentmouse; HBV; APOBEC; restriction factor; cytidine deaminase
The impact of multiple splice sites in human L1 elements
Keywords: APOBEC; cytidine deaminases family of proteins; EBV SM protein; Epstein-Barr virus SM protein; FL1; Full-length L1; LINE-1, L1; Long interspersed element-1; L1.3; one of the active human L1 elements; L1spa; one of the active mouse L1 elements; ORF1; ope
Natural resistance to HIV infection: The Vif–APOBEC interaction
Keywords: HIV; APOBEC; Vif; Viral resistance; Hypermutation
Human APOBEC3B is a potent inhibitor of HIV-1 infectivity and is resistant to HIV-1 Vif
Keywords: APOBEC; apolipoprotein B mRNA editing enzyme catalytic polypeptide; AGM; African green monkey; HA; influenza virus hemagglutinin; HIV; human immunodeficiency virus; MLV; murine leukemia virus; NC; nucleocapsid; PBMC; peripheral blood mononuclear cells; SI
Newly identified host factors modulate HIV replication
Keywords: HIV; TRIM5α; APOBEC; MVB;