دانلود مقالات ISI درباره Bdl + ترجمه فارسی

Targeting Keap-1/Nrf-2 pathway and cytoglobin as a potential protective mechanism of diosmin and pentoxifylline against cholestatic liver cirrhosis

Keywords: DS; diosmin; PTX; pentoxifylline; BDL; bile duct ligation; ROS; reactive oxygen species; GSH; reduced glutathione; MDA; malondialdehyde; SOD; superoxide dismutase; TGF-β; transforming growth factor-beta; HYP; hydroxyproline; P38−MAPK; P38 mitogen activ

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Transcriptomics provides mechanistic indicators of mixture toxicology for IMX-101 and IMX-104 formulations in fathead minnows (Pimephales promelas)

Keywords: 95% C.I.; 95% confidence interval; BDL; below detection limits; cRNA; complementary RNA; DAVID; Database for Annotation, Visualization and Integrated Discovery; DNAN; 2,4-dinitroanisole; HMX; cyclotetramethylene-tetranitramine; IM; insensitive munition; K

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer

Keywords: FXR; Obeticholic Acid; S-Adenosylmethionine; Ursodeoxycholic Acid; AP-1; activator protein-1; ARE; antioxidant response element; BDL; bile duct ligation; BrdU; 5-bromo-2'deoxyuridine; CCA; cholangiocarcinoma; FXR; farnesoid X receptor; GSH; reduced glut

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Portal myofibroblasts are sensitive to CCN-mediated endoplasmic reticulum stress-related apoptosis with potential to attenuate biliary fibrogenesis

Keywords: CCN proteins; ER stress; Unfolded protein response; Matricellular proteins; Portal myofibroblasts; TUDCA; α-SMA; α-smooth muscle actin; ATF6; activating transcription factor 6; BDL; bile duct ligation; eIF2α; eukaryotic translation initiation factor 2Î

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Natural product andrographolide alleviated APAP-induced liver fibrosis by activating Nrf2 antioxidant pathway

Keywords: APAP; acetaminophen; Nrf2; nuclear factor erythroid 2-related factor 2; Andro; andrographolide; HSCs; hepatic stellate cells; ROS; reactive oxygen species; ECMs; extracellular matrix proteins; Egr1; early growth factor 1; Keap1; kelch-like ECH-associated

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Systemic inflammation without gliosis mediates cognitive deficits through impaired BDNF expression in bile duct ligation model of hepatic encephalopathy

Keywords: AEBSF; 4-(2-Aminoethyl) benzene sulfonyl fluoride hydrochloride; ALP; Alkaline phosphatase; ALT; Alanine transaminase; AST; Aspartate transaminase; BBB; Blood brain barrier; BDL; Bile duct ligation; BDNF; Brain derived neurotrophic factor; BSA; Bovine ser

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Fas Receptor Activation by Endogenous Opioids Is A New Mechanism for Cardiomyopathy in Cirrhotic Rats

Keywords: BDL; bile duct ligation; CC; cirrhotic cardiomyopathy; H&E; Hematoxylin and Eosin; MAPKs; mitogen-activated protein kinases; NO; nitric oxide; qRT-PCR; Real-Time Reverse Transcription PCR; cirrhotic cardiomyopathy; apoptosis; opioid; Fas;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Glechoma hederacea extracts attenuate cholestatic liver injury in a bile duct-ligated rat model

Keywords: ALT; alanine aminotransferase; ANOVA; one-way analysis of variance; AST; aspartate aminotransferase; BDL; bile duct ligation; CTGF; connective tissue growth factor; ELISA; enzyme-linked immunosorbent assay; EMSA; electrophoretic mobility shift assay; GAPD

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration

Keywords: 3MA; 3-methyladenine; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ATP1B2; ATPase Na+/K+ transporting subunit beta 2; BDL; bile duct ligation; Cav1; Caveolin 1; CD31; platelet endothelial cell adhesion molecule-1, PECAM-1; cGMP; cyclic

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Toxic elements and associations with hematology, plasma biochemistry, and protein electrophoresis in nesting loggerhead sea turtles (Caretta caretta) from Casey Key, Florida

Keywords: Electrophoresis; Heavy metal; Keratin; Inorganic contaminant; Marine turtle; Toxicology; α; alpha; A:G; albumin:globulin ratio; ALKP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AU; absorbance unit; β; beta; BDL

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Bile acid receptor TGR5 overexpression is associated with decreased intestinal mucosal injury and epithelial cell proliferation in obstructive jaundice

Keywords: ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BDL; bile duct ligation; CDCA; chenodeoxycholic acid; DAO; diamine oxidase; DCA; deoxycholic acid; D-lactate; D(-)-lactic acid; EdU; 5-ethynyl-2′-deoxyuridine; G

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

The increased toxicity of UV-degraded nitroguanidine and IMX-101 to zebrafish larvae: Evidence implicating oxidative stress

Keywords: 95% C.I.; 95% confidence interval; BDL; below detection limits; cRNA; complementary RNA; DAVID; database for annotation, visualization and integrated discovery; DNAN; 2,4-dinitroanisole; GSEA; gene set enrichment analysis; IM; insensitive munition; KEGG;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Clinical outcomes in patients with bile leaks treated via ERCP with regard to the timing of ERCP: a large multicenter study

Keywords: AE; adverse event; BDL; bile duct leaks;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6

Keywords: HCC; Cancer Stem Cells; HuR; Hepatocarcinogenesis; ACTA2; α-smooth muscle actin; Ad; adenovirus; aHSC; activated hepatic stellate cell; AKT; AKT serine/threonine kinase 1; ARE; AU-rich element; BDL; bile duct ligation; BSC; BDL-derived aHSC cell line; CC

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2017 سفارش ترجمه

Research ArticleHic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis through upregulation of Smad7 in mice

Keywords: Ad-Hic-5/flag; adenovirus-mediated flag-tagged Hic-5; Ad-β-gal; adenovirus-mediated β-galactosidase; α-SMA; alpha smooth muscle actin; BDL; bile duct ligation; CCl4; carbon tetrachloride; COL; collagen; ECM; extracellular matrix; GAPDH; glyceraldehyde

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Alterations in the intrinsic electrophysiological properties of Purkinje neurons in a rat model of hepatic encephalopathy: Relative preventing effect of PPARγ agonist

Keywords: Kynurenic acid (PubChem CID: 3845); Pioglitazone hydrochloride (PubChem CID: 60560); Picrotoxin (PubChem CID: 531135)Cirrhosis; BDL; Pioglitazone; Excitability; Cerebellum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Maternal transfer and sublethal immune system effects of brevetoxin exposure in nesting loggerhead sea turtles (Caretta caretta) from western Florida

Keywords: ACN; acetonitrile; ALT; alanine aminotransferase; ALKP; alkaline phosphatase; AST; aspartate aminotransferase; BDL; below detection limits; BUN; blood urea nitrogen; CK; creatine kinase; ELISA; enzyme-linked immunosorbent assay; LC-MS/MS; liquid chromat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleAmmonia produces pathological changes in human hepatic stellate cells and is a target for therapy of portal hypertension

Keywords: 3-NTyrosine; 3-Nitrotyrosine; α-SMA; alpha Smooth Muscle Actin; AAs; Amino acid-rich; ATF6; Activating transcription factor 6; BDL; Bile Duct Ligation; BiP; Immunoglobulin heavy chain binding protein; BrdU; 5-Bromo-2-Deoxyuridine; carboxy-DCF; (5(6)-Carb

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Adenoviral CCN gene transfers induce in vitro and in vivo endoplasmic reticulum stress and unfolded protein response

Keywords: Ad-CCN1-4; Ad5-CMV-CCN1-4; Ad-Luc; Ad5-CMV-Luc; ATF6; activating transcription factor 6; β-Gal; β-galactosidase; BDL; bile duct ligation; ECM; extracellular matrix; ER; endoplasmic reticulum; ERAD; ER-associated protein degradation; h; human; HSC; h

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Epithelial Transforming Growth Factor-β Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma

Keywords: TGFβ; Signal Transduction; Mouse Model; Liver Cancer; α-SMA; α-smooth muscle actin; BDL; bile duct ligation; DDC; 3,5-diethoxycarbonyl-1,4-dihydro-collidin; DEN; diethylnitrosamine; HCC; hepatocellular carcinoma; HSC; hepatic stellate cell; mRNA; messe

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Tissue-specific expression of Arabidopsis NPR1 gene in rice for sheath blight resistance without compromising phenotypic cost

Keywords: SAR; systemic acquired resistance; PDA; potato dextrose agar; BDL; bioassay using detached leaf; DPI; days post inoculation; PDI; percent disease index; MS; Murashige and Skoog; Yield penalty; Transgenic rice; Systemic acquired resistance; Green tissue-sp

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit

Keywords: EMT; epithelial-mesenchymal transition; HSCs; hepatic stellate cells; MET; mesenchymal-epithelial transition; ECM; extracellular matrix; ACE2; angiotensin converting enzyme 2; Ang II; angiotensin II; Ang-1-7; angiotensin-(1-7); ASC; apoptosis associat

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2016 سفارش ترجمه

Research Articleβ-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis

Keywords: β-PDGFR; beta platelet-derived growth factor receptor; HCV; hepatitis C virus; CCl4; carbon tetrachloride; DEN; diethyl nitrosamine; GFAP; glial fibrillary acidic protein; BDL; bile duct ligation; bw; body weight; AST; aspartate aminotransferase; ALT; al

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cholestasis induced antinociception and decreased gene expression of MOR1 in rat brain

Keywords: ANOVA; analysis of variance; BDL; bile duct ligation; MOR1; mu-opioid receptor 1; %MPE; percentage maximum possible effect; PCR; polymerase chain reaction; PFC; prefrontal cortex; RT-PCR; reverse transcription-polymerase chain reaction; cholestasis; antin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The effects of intra-dorsal hippocampus infusion of pregnenolone sulfate on memory function and hippocampal BDNF mRNA expression of biliary cirrhosis-induced memory impairment in rats

Keywords: AP5; DL-2-Amino-5-phosphonopentanoic acid; BDL; bile duct ligation; BDNF; brain-derived neurotrophic factor; HE; hepatic encephalopathy; LTP; long-term potentiation; MHE; minimal HE; NMDA; N-methyl-d-aspartate; PREGS; pregnenolone sulfate; liver cirrhosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MKL1 is an epigenetic modulator of TGF-β induced fibrogenesis

Keywords: TGF-β; transforming growth factor; MKL1; megakaryoblastic leukemia 1; BDL; bile duct ligation; ChIP; chromatin immunoprecipitation; COMPASS; complex proteins associated with SET; TF; transcription factor; Epigenetics; Transcriptional regulation; Portal f

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis

Keywords: LCA; lithocholic acid; UDCA; ursodeoxycholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic acid; CA; cholic acid; TCA; taurocholic acid; GCDC; glycochenodeoxycholic acid; TCDC; taurochenodeoxycholic acid; GCA; glycocholic acid; GDCA; glycodeoxycholi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

GCDCA down-regulates gene expression by increasing Sp1 binding to the NOS-3 promoter in an oxidative stress dependent manner

Keywords: Cholestatic liver disease; Endothelial nitric oxide synthase; Oxidative stress; Transcription factor Sp1; Glycochenodeoxycholic acid; ADHP; 0-acetyl-3, 7-dihydroxyphenoxazine; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BDL; bile duct

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticlePioglitazone decreases portosystemic shunting by modulating inflammation and angiogenesis in cirrhotic and non-cirrhotic portal hypertensive rats

Keywords: PPARγ; Peroxisome proliferator-activated receptor gamma; PIO; Pioglitazone; VEH; Vehicle; BDL; Bile duct ligation; PPVL; Partial portal vein ligation; SO; Sham-operation; SMABF; Splanchnic blood flow; PP; Portal pressure; PSS; Portosystemic shunting; PIG

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Ezetimibe enhances macrophage reverse cholesterol transport in hamsters: Contribution of hepato-biliary pathway

Keywords: RCT; reverse cholesterol transport; CETP; cholesterol ester transfer protein; BDL; bile duct ligation; TICE; transintestinal cholesterol efflux; LDLR; low-density lipoprotein receptor; ABCA1; ATP-binding cassette transporter A; NPC1L1; Niemann-Pick C1-l

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleNod2 deficiency protects mice from cholestatic liver disease by increasing renal excretion of bile acids

Keywords: NASH; non-alcoholic steatohepatitis; Nod; nucleotide oligomerization domain; MDP; muramyl dipeptide; IL; interleukin; BDL; bile duct ligation; ALT; alanine aminotransferase; ALP; alkaline phosphatase; TNF; tumor necrosis factor; LPS; lipopolysaccharide; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice

Keywords: Fmo3; flavin-containing monoxygenase-3; APAP; acetaminophen; ANIT; alpha-naphthyl isothiocyanate; BDL; bile duct ligation; CCl4; carbon tetrachloride; AlOH; allyl alcohol; Nrf2; nuclear factor (erythroid-derived 2)-like 2; Flavin-containing monoxygenase-3

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Original ResearchFull Report: Basic and Translational-LiverVascular Endothelial Growth Factor Promotes Fibrosis Resolution and Repair in Mice

Keywords: Sinusoidal Endothelial Cell; Hepatic Sinusoid; Extracellular Matrix; Liver Damage; AdCXCL9; adenovirus expressing murine CXCL9; AdVEGF; adenovirus expressing murine VEGF; BDL; bile duct ligation; CCl4; carbon tetrachloride; CJ; cholecystojejunostomy; CSF1

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

ReviewCharacterization of animal models for primary sclerosing cholangitis (PSC)

Keywords: ANA; anti-nuclear antibody; ANCA; anti-neutrophil cytoplasmic antibody; ANIT; alpha-naphthylisothiocyanate; BA; bile acids; BDL; bile duct ligation; BEC; biliary epithelial cell; CCC; cholangiocellular carcinoma; Cftr; cystic fibrosis transmembrane conduc

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticlePDX-1/Hes-1 interactions determine cholangiocyte proliferative response to injury in rodents: Possible implications for sclerosing cholangitis

Keywords: PDX-1; Pancreatic Duodenal Homeobox-1; Hes-1; hairy and enhancer of split 1; NRC; normal rat cultured cholangiocytes; BDL; bile duct ligation; DDC; 3,5-diethoxycarbonyl-1,4-dihydrocollidine; PCNA; proliferating cell nuclear antigen; PSC; primary sclerosin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: A novel target for the attenuation of portal hypertension

Keywords: BDL; bile duct ligation; b. w; body weight; CB2; cannabinoid receptor 2; Gp 1a; N-(Piperidin-1-yl)-1-(2,4-dichlorop­henyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3­-carboxamide; GW 9662; 2-Chloro-5-nitro-N-phenylbenzamide; HO; heme oxygenase; JWH-133

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Interorgan metabolism of ornithine phenylacetate (OP)-A novel strategy for treatment of hyperammonemia

Keywords: HE; hepatic encephalopathy; PA; phenylacetate; PAGN; phenylacetylglutamine; OP; ornithine phenylacetate; BDL; bile duct ligation; SHAM; sham-operation; OAT; ornithine-ω-aminotransferase; GSADH; glutamate-γ-semialdehyde dehydrogenase; GS; glutamine synth

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticleSphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis

Keywords: S1P; sphingosine-1-phosphate; SphK; sphingosine kinase; S1PR; S1P receptor; VEGF; vascular endothelial growth factor; HSC; hepatic stellate cells; Ang1; angiopoietin 1; SKI; 2-(p-hydroxyanilino)-4-(p-chloro-phenyl)thiazole; BDL; bile duct ligation; HPLC;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis

Keywords: HRS; hepatorenal syndrome; NGAL/LCN2; lipocalin 2 protein; LPS; lipopolysaccharide; ConA; Concanavalin A; BDL; bile duct ligation; MCP-1/CCL2; monocyte chemoattractant protein-1/C-C chemokine ligand-2; Lipocalin; LCN2; NGAL; BDL; CCl4; Acute phase respo

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Occludin dislocation in brain capillary endothelium of rats with bile duct ligation induced cholestasis

Keywords: BBB; blood-brain barrier; TJ; tight junction; BDL; bile duct ligated; PB; phosphate buffer; RT; room temperature; PLT; progressive lowering of temperature; BSA; bovine serum albumin; Tight junction; Brain endothelium; Electron microscopy; Occludin reloc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleRegulatory T cells suppress sickness behaviour development without altering liver injury in cholestatic mice

Keywords: BDL; bile duct ligation; PBC; primary biliary cirrhosis; PSC; primary sclerosing cholangitis; Treg; regulatory T cell; Fatigue; Cytokine; Liver-brain axis; Symptom; Endothelium; IL-6;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Complement factor C5 deficiency significantly delays the progression of biliary fibrosis in bile duct-ligated mice

Keywords: α-SMA; alpha-smooth muscle actin; BA; bile acid; BDL; bile duct ligation; Col; collagen; FXR; farnesoid X receptor; HE; Hematoxilin&Eosin; Ntcp; Na-dependent taurocholate transporter; MMP; matrix metalloproteinase; Mrp; multidrug resistance associated pr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticlePrevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression

Keywords: AKI; acute kidney injury; BDL; bile duct ligation; HRS; hepatorenal syndrome; IL-6; interleukin 6; IP; intraperitoneal; LPS; lipopolysaccharide; NFκB; nuclear factor kappa B; Norflox; norfloxacin; SBP; spontaneous bacterial peritonitis; SIRS; systemic in

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleIntestinal decontamination inhibits TLR4 dependent fibronectin-mediated cross-talk between stellate cells and endothelial cells in liver fibrosis in mice

Keywords: LPS; lipopolysaccharide; TLR4; Toll-like receptor-4; LEC; liver endothelial cells; HSC; hepatic stellate cells; FN; fibronectin; BDL; bile duct ligation; LPSBP; lipopolysaccharide binding protein; vWF; von Willebrand's factor; PDGFR-β; platelet-derived

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleAdenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats

Keywords: HSC; hepatic stellate cells; PDGF; platelet-derived growth factor; PDGFRβ; PDGF receptor β; BDL; bile duct-ligated; CCl4; carbon tetrachloride; MAP; mean arterial pressure; PP; portal pressure; HR; heart rate; β-gal; β-galactosidase; pfu; plaque-formi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and biological evaluation of ester prodrugs of benzafibrate as orally active hypolipidemic agents

Keywords: Benzafibrate; Prodrugs; Hypolipidemic activity; Physicochemical properties; HPLC; high performance liquid chromatography; GC; gas chromatograph; API; active pharmaceutical ingredient; DMAc; dimethylacetamide; Ar; aryl; PPAR-α; peroxisome proliferator-act

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleHSC-specific inhibition of Rho-kinase reduces portal pressure in cirrhotic rats without major systemic effects

Keywords: BDL; bile duct ligation; b.w.; body weight; CCl4; tetracarbon chloride intoxication; HSA; human serum albumin; HSC; hepatic stellate cells; MAP; mean arterial pressure; M6P; mannose-6-phosphate; MLC; myosin light chains; MLCP; myosin light chain phosphata

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo

Keywords: HSC; hepatic stellate cell; NADPH oxidase (NOX); nicotinamide adenine dinucleotide phosphate reduced oxidas; BDL; bile duct ligation; TGF-β1; transforming growth factor-β; TNF-α; tumor necrosis factor α; αSMA; α-smooth muscle actin; ALT; alanine ami

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds

Keywords: ABC; ATP-binding cassette; BDL; bile duct ligation; CAT; chloramphenicol acetyltransferase; CDDP; cisplatin; CGamF; cholylglycylamidofluorescein; FITC; fluorescein isothiocyanate; MRP; multidrug resistance-associated protein; MTX; mitoxantrone; NE; nuclea

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleBacterial translocation and changes in the intestinal microbiome in mouse models of liver disease

Keywords: ALT; alanine aminotransferase; BDL; bile duct ligation; CCl4; carbon tetrachloride; CFU; colony-forming unit; LBP; lipopolysaccharide-binding protein; PCoA; Principal Coordinates Analysis; LPS; lipopolysaccharide; OTU; Operational Taxonomic Unit; TLR; Tol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه