دانلود مقالات ISI درباره c-met + ترجمه فارسی

Prognostic value of c-MET in head and neck cancer: A systematic review and meta-analysis of aggregate data

Keywords: c-met; SCCHN; squamous cell carcinoma of the head and neck; c-MET; mesenchymal-epithelial transition factor; HGF; hepatocyte growth factor; PRISMA; Preferred Reporting Items for Systematic Reviews and Meta-Analyses; TNM; Tumour Node Metastasis; HPV; human papill

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Co-targeting c-Met and DNA double-strand breaks (DSBs): Therapeutic strategies in BRCA-mutated gastric carcinomas

Keywords: c-met; Gastric cancer; Hepatocyte growth factor receptor; c-MET; BRCA proteins; HR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel 7-azaindole derivatives bearing dihydropyridazine moiety as c-Met kinase inhibitors

Keywords: c-met; c-Met; Receptor tyrosine kinase; Anti-tumor; 7-Azaindole derivatives; Dihydropyridazine;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Prostacyclin mimetics afford protection against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice

Keywords: c-met; Acute liver failure; Hepatoprotection; IP receptor; Reactive oxygen species; Signal transducers and activators of transcription; ALF; acute liver failure; ALT; alanine aminotransferase; ANOVA; analysis of variance; AST; aspartate aminotransferase; c-Met;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

HGF induces EMT in non-small-cell lung cancer through the hBVR pathway

Keywords: c-met; HGF; c-Met; hBVR; EMT; NSCLC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel pyrrolo-pyridine/pyrimidine derivatives bearing pyridazinone moiety as c-Met kinase inhibitors

Keywords: c-met; Pyrrolo[2,3-b]pyridines; Pyrrolo[2,3-d]pyrimidines; Pyridazinone; c-Met; Antitumor activity; Docking study;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives as selective c-Met inhibitors

Keywords: c-met; c-Met; Antitumor activity; Synthesis; Molecular docking; 6,7-Disubstituted-4-(2-fluorophenoxy)quinolines;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Antitumor activity, pharmacokinetics, tumor-homing effect, and hepatotoxicity of a species cross-reactive c-Met antibody

Keywords: c-met; Cancer; c-Met; Fully human antibody; Cross-reactivity; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Development of efficient docking strategies and structure-activity relationship study of the c-Met type II inhibitors

Keywords: c-met; c-Met; Docking; Binding affinity; Conformation; Force field; Computational screening;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Structure-based design, synthesis, and evaluation of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel c-Met inhibitors

Keywords: c-met; pyrazolo[4,3-c]pyridine; Synthesis; c-Met; Inhibitors; Cancer;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors

Keywords: c-met; c-Met; Inhibitor; Type II; Pyridine; Pyrimidine; Anti-cancer;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

MicroRNA-1 inhibits ovarian cancer cell proliferation and migration through c-Met pathway

Keywords: c-met; Ovarian cancer; miR-1; c-Met; Proliferation; Migration;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and biological evaluation of novel 6,11-dihydro-5H-benzo[e]pyrimido- [5,4-b][1,4]diazepine derivatives as potential c-Met inhibitors

Keywords: c-met; c-Met; tyrosine kinase; Diazepine derivatives; Synthesis; Antitumor;

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of 3-substituted-6-(1-(1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)ethyl)quinoline derivatives as highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitors via metabolite profiling-based structural optimization

Keywords: c-met; c-Met; 3-Substituted quinolines; Triazolopyrazine; Metabolism; SAR; Docking study;

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel pyrrolo[2,3-b]pyridine derivatives bearing 1,2,3-triazole moiety as c-Met kinase inhibitors

Keywords: c-met; Synthesis; Pyrrolo[2,3-b]pyridine derivatives; 1,2,3-Triazole; c-Met; Antiproliferative activity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of long non-coding RNA TUG1 on gastric cancer cell transference and invasion through regulating and controlling the expression of miR-144/c-Met axis

Keywords: c-met; lncRNA-TUG1; Gastric carcinoma; Transference; Invasion; microRNA-144; c-Met

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and antiproliferative activity of 6,7-disubstituted-4-phenoxyquinoline derivatives bearing the 2-oxo-4-chloro-1,2-dihydroquinoline-3-carboxamide moiety

Keywords: c-met; Synthesis; Quinoline derivatives; 2-Oxo-4-chloro-1,2-dihydroquinoline; c-Met; Antiproliferative activity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Tyrosine phosphorylation of RalGDS by c-Met receptor blocks its interaction with Ras

Keywords: c-met; RalGDS; Ral; Ras; c-Met; Tyrosine phosphorylation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

c-Met expression and MET amplification in malignant pleural mesothelioma

Keywords: c-met; c-Met; Mesothelioma; MET; Receptor tyrosine kinase; Tyrosine kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

IGF1R and c-met as therapeutic targets for colorectal cancer

Keywords: c-met; Colorectal cancer; IGF1R; c-Met; Receptor tyrosine kinase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Predictive role of the overexpression for CXCR4, C-Met, and VEGF-C among breast cancer patients: A meta-analysis

Keywords: c-met; CXCR4; C-Met; VEGF-C; Overexpression; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Design and synthesis of novel benzo[d]oxazol-2(3H)-one derivatives bearing 7-substituted-4-enthoxyquinoline moieties as c-Met kinase inhibitors

Keywords: c-met; c-Met; Benzo[d]oxazol-2(3H)-one-quinolone; Molecular hybridization; Anti-cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer proliferation, migration and invasion

Keywords: c-met; Bioassay-guided; Breast cancer; c-Met; Endophyte; Meleagrin; Olive tree; Penicillum chrysogenum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress

Keywords: c-met; c-Met; Oxidative stress; Cholestasis; Cholesterol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs

Keywords: c-met; VEGFR; c-Met; Dual inhibitor; Anti-cancer drugs

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Human papillomavirus oncoprotein E6 upregulates c-Met through p53 downregulation

Keywords: c-met; Human papillomavirus; c-Met; p53; Head and neck cancer;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of a novel 6,7-disubstituted-4-(2-fluorophenoxy)quinolines bearing 1,2,3-triazole-4-carboxamide moiety as potent c-Met kinase inhibitors

Keywords: c-met; c-Met; Synthesis; Antitumor activity; Quinoline derivatives;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

(1S,2E,4S,7E,11E)-2,7,11-Cembratriene-4,6-diol semisynthetic analogs as novel c-Met inhibitors for the control of c-Met-dependent breast malignancies

Keywords: c-met; Breast cancer; c-Met; Hit-to-lead; Rational design; Semisynthesis; Tobacco cembranoids 1;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Antitumor effect and safety profile of systemically delivered oncolytic adenovirus complexed with EGFR-targeted PAMAM-based dendrimer in orthotopic lung tumor model

Keywords: c-met; Adenovirus; Oncolytic adenovirus; Decorin; shRNA; c-Met; PEGylation; PAMAM; Dendrimer; EGFR; Erbitux; Cetuximab; Cancer; Gene therapy

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2

Keywords: c-met; Oxime; c-Met; VEGFR-2; Synergistically collaborate; Cancers;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Clinicopathological significance and concordance analysis of c-MET immunohistochemistry in non-small cell lung cancers: A meta-analysis

Keywords: c-met; Non-small cell lung carcinoma; c-MET; Immunohistochemistry; Meta-analysis; Diagnostic test accuracy review;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Cancer Stem Cells, Epithelial to Mesenchymal Markers, and Circulating Tumor Cells in Small Cell Lung Cancer

Keywords: c-met; CSCs; CTCs; EMT; c-MET; SCLC;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and biological evaluation of 4-(2-fluorophenoxy)-3,3′-bipyridine derivatives as potential c-met inhibitors

Keywords: c-met; Synthesis; Bipyridine derivatives; Aza-aryl formamides; c-Met; Cytotoxicity;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

The novel c-Met inhibitor capmatinib mitigates diethylnitrosamine acute liver injury in mice

Keywords: c-met; Diethylnitrosamine; C-Met; Capmatinib; 4-Hydroxynonenal;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of 6-(difluoro(6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline as a highly potent and selective c-Met inhibitor

Keywords: c-met; Antitumor; c-Met; Kinase inhibitor; Triazolotriazines;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Expression and tissue distribution of hepatocyte growth factor (HGF) and its receptor (c-Met) in alpacas (Vicugna pacos) skins associated with white and brown coat colors

Keywords: c-met; HGF; c-Met; Alpaca; Coat color; Skin

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Design and synthesis of constrained analogs of LCRF-0004 as potent RON tyrosine kinase inhibitors

Keywords: c-met; RON; c-Met; RTK inhibitors; Bicyclic head group; Molecular docking; Homology model

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Design and synthesis of close analogs of LCRF-0004, a potent and selective RON receptor tyrosine kinase inhibitor

Keywords: c-met; RON; c-Met; RTK inhibitors; Head group; Thieno[3,2-b]pyridine scaffold; Oncology;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors

Keywords: c-met; c-Met; Tyrosine kinase; Pyridazinone; Structure-based design; MSC2156119

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Signal transduction and downregulation of C-MET in HGF stimulated low and highly metastatic human osteosarcoma cells

Keywords: c-met; Osteosarcoma; C-MET; Signal transduction; TPR-MET;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis and RON receptor tyrosine kinase inhibitory activity of new head groups analogs of LCRF-0004

Keywords: c-met; RON; c-Met; RTK inhibitors; Head group; Molecular docking; RON homology model; Oncology

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Heterogeneity of c-Met expression in Chinese gastric cancer patients

Keywords: c-met; Gastric cancer; c-Met; Heterogeneity; Homogeneity; Amplification; Overexpression

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of metastatic ability and drug resistance in pulmonary adenocarcinoma by matrix rigidity via activating c-Met and EGFR

Keywords: c-met; Adenocarcinoma; c-Met; Drug resistance; Epidermal growth factor receptor; Lung fibrosis; Matrix rigidity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Tivantinib (ARQ 197) efficacy is independent of MET inhibition in non-small-cell lung cancer cell lines

Keywords: c-met; Tivantinib; ARQ 197; c-MET; Lung cancer; Crizotinib;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Combination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth

Keywords: c-met; OS; osteosarcoma; miR or miRNA; microRNA; ncRNA; noncoding RNA; miR-34a; microRNA-34a; pre-miR-34a or mir-34a; pre-microRNA-34a; tRNA/mir-34a; transfer RNA fusion pre-miR-34a; CDK6; cyclin-dependent kinase 6; c-MET; hepatocyte growth factor receptor; SIRT

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Metastasis-associated in colon cancer-1 upregulates vascular endothelial growth factor-C/D to promote lymphangiogenesis in human gastric cancer

Keywords: c-met; MACC1; metastasis-associated in colon cancer-1; GC; gastric cancer; VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; MMP; matrix metalloproteinase; HGF; hepatocyte growth factor; c-Met; mesenchymal-epithelial

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Sp1 transcription factor: A long-standing target in cancer chemotherapy

Keywords: c-met; Anticancer drugs; Prognosis; Sp1; Sp3; Transcription factors; Targeted therapy; AMPKα; AMP-activated protein kinase alpha catalytic subunit; Bcl-2; B cell/lymphoma 2; Bcl-w; member of the Bcl-2 family; Bid; BH3 interacting domain death agonist; CDK; cycl

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of triazolo[4,5-b]pyrazine derivatives as hepatocyte growth factor receptor inhibitors through structure-activity relationships and molecular docking simulations

Keywords: c-met; c-MET; Cancer therapy; 3D-QSAR; Molecular docking; Analogs design;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Design and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives bearing an imidazolone moiety as c-Met kinase inhibitors

Keywords: c-met; c-Met; Antitumor activity; Quinoline derivatives; Imidazolone-4-carboxamide;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets

Keywords: c-met; Serine protease; Peptidomimetic; Benzamidine; Hepsin; Matriptase; HGFA; Small-molecule; Therapeutic; c-MET; RON; HGF; MSP; Receptor tyrosine kinase; Cancer; Cell-signaling; Growth factor; Structure-based drug design; Enzyme inhibitor;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه