Keywords: مهار کننده های کربن انیدراتا; Imidazoline-5-ones; Sulphonamide derivatives; p38αMAPK inhibitors; Carbonic anhydrase inhibitors;
مقالات ISI مهار کننده های کربن انیدراتا (ترجمه نشده)
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Keywords: مهار کننده های کربن انیدراتا; Primary sulfonamide; Electron-withdrawing group; Nucleophilic aromatic substitution; SMILES rearrangement; Reactivity-matched substrates; Carbonic anhydrase inhibitors; Isoform-selectivity;
Keywords: مهار کننده های کربن انیدراتا; Benzenesulfonamides; Isatin; Carbonic anhydrase inhibitors; Synthesis; Molecular docking;
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Isoform selectivity; Zinc binding group; Primary sulfonamide; Aromatic sulfochlorination; Alternative binding mode;
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Isatin; Benzenesulfonamide; Anticancer; Apoptosis;
Keywords: مهار کننده های کربن انیدراتا; Sulfonamide; Benzimidazole; Metal complexes; Antibacterial activity; Carbonic anhydrase inhibitors
Keywords: مهار کننده های کربن انیدراتا; Heart failure; Carbonic anhydrase inhibitors; Intracellular pH; Myocardial infarction
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Glaucoma; Intraocular pressure; Canine; Feline;
Keywords: مهار کننده های کربن انیدراتا; Glaucoma; Medical therapy; Carbonic anhydrase inhibitors; Prostaglandin analogues; Novel therapies; Delivery systems;
Keywords: مهار کننده های کربن انیدراتا; Protein database search; Molecular docking; Molecular engineering; Carbonic anhydrase inhibitors; Multi-targeted agents; hERG ion channel
Synthesis of novel 4-functionalized 1,5-diaryl-1,2,3-triazoles containing benzenesulfonamide moiety as carbonic anhydrase I, II, IV and IX inhibitors
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Isoforms I, II, IV, IX; Benzenesulfonamide; 1,2,3-Triazole; CA; Carbonic anhydrase; hCA; human carbonic anhydrase; CAIs; Carbonic anhydrase inhibitors; AAZ; Acetazolamide; Ki; Inhibition constant; nM; nanomolar; μM; micromo
Structural investigations on coumarins leading to chromeno[4,3-c]pyrazol-4-ones and pyrano[4,3-c]pyrazol-4-ones: New scaffolds for the design of the tumor-associated carbonic anhydrase isoforms IX and XII
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; 2H-cromen-2-one; chromeno[4,3-c]pyrazol-4-one; pyrano[4,3-c]pyrazol-4-one; Anticancer agents;
Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase; Carbonic anhydrase inhibitors; Anticonvulsant; MES; sc-PTZ; Toxicity;
1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Multigram synthesis; Isoform selectivity; Picomolar inhibition; Primary sulfonamide; Ocular hypertension; X-ray crystallography;
Isatin analogs as novel inhibitors of Candida spp. β-carbonic anhydrase enzymes
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase; Carbonic anhydrase inhibitors; Candida; Isatins; Sulfonamides
New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors
Keywords: مهار کننده های کربن انیدراتا; MCF-7; Pyrazolo[4,3-e][1,2,4]triazine; Sulfonamides; Carbonic anhydrase inhibitors; Cytotoxicity;
Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Isothermal titration calorimetry; X-ray crystallography; Intrinsic thermodynamics of binding; Structure-thermodynamics relationships;
Probing the 'bipolar' nature of the carbonic anhydrase active site: Aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms
Keywords: مهار کننده های کربن انیدراتا; Drug discovery; Carbonic anhydrase inhibitors; Isoform selectivity; Anti-glaucoma drugs; 1,3-oxadiazol-5-yl aromatics; Chemoselective sulfochlorination;
Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity
Keywords: مهار کننده های کربن انیدراتا; Sulfonamides; MDA-MB-231; MCF-7; Cytotoxicity; Carbonic anhydrase inhibitors; Pyrazolo[4,3-e][1,2,4]triazine;
Dorzolamide-induced relaxation of porcine retinal arterioles in vitro depends on nitric oxide but not on acidosis in vascular smooth muscle cells
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Dorzolamide; Retina; Relaxation; Nitric oxide; Intracellular acidosis;
Screening of novel chemical compounds as possible inhibitors of carbonic anhydrase and photosynthetic activity of photosystem II
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase; Photosystem II; New inhibitors; Carbonic anhydrase inhibitors; Photosynthetic inhibitors;
Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties
Keywords: مهار کننده های کربن انیدراتا; Pyrrolopyrimidines; Sulfonamide; Cytotoxic activity; Carbonic anhydrase inhibitors; Molecular docking
Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening
Keywords: مهار کننده های کربن انیدراتا; Virtual screening; Molecular docking; Carbonic anhydrase inhibitors; Sulfonamides;
4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Isothermal titration calorimetry; Thermal shift assay; ThermoFluor®; Fluorinated benzenesulfonamide; X-ray crystallography;
Effect of sulfonamides as carbonic anhydrase VA and VB inhibitors on mitochondrial metabolic energy conversion
Keywords: مهار کننده های کربن انیدراتا; Sulfonamides; Carbonic anhydrase inhibitors; Mitochondrial modified electrodes; Metabolic energy conversion
Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Benzenesulfonamides; Structure–activity relationship; Molecular docking
Structure, function and applications of carbonic anhydrase isozymes
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase; Drug target; Bicarbonates metabolism; Carbonic anhydrase inhibitors; Structure–function relationship; Carbon capture; Drug designing and drug screening
Anticancer and radiosensitizing evaluation of some new pyranothiazole-Schiff bases bearing the biologically active sulfonamide moiety
Keywords: مهار کننده های کربن انیدراتا; Pyranothiazole; Sulfonamides; Carbonic anhydrase inhibitors; Cytotoxicity; Radiosensitizing activities
Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitors
Keywords: مهار کننده های کربن انیدراتا; Isoquinolines; Microwave assisted organic synthesis; Carbonic anhydrase inhibitors; hCA IX; hCA XIV;
Discovery of new chromone containing sulfonamides as potent inhibitors of bovine cytosolic carbonic anhydrase
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase; Carbonic anhydrase inhibitors; Formylchromones; Sulfonamides
Chronic impact of topiramate on acid-base balance and potassium in childhood
Keywords: مهار کننده های کربن انیدراتا; Acid–base equilibrium; Acidosis; Carbonic anhydrase inhibitors; Hypokalemia; Topiramate
New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors
Keywords: مهار کننده های کربن انیدراتا; BSA; benzenesulfonamide; HPM; hydroxypyrimidinone; CA; carbonic anhydrase; MMP; matrix metalloproteinase; ZBG; zinc-binding group; HA; hydroxamic acid; Hydroxypyrimidinones; Carbonic anhydrase inhibitors; Sulfonamides; MMP inhibitors;
3D-QSAR study of benzene sulfonamide analogs as carbonic anhydrase II inhibitors
Keywords: مهار کننده های کربن انیدراتا; Benzene sulfonamides; Carbonic anhydrase inhibitors; 3D-QSAR; CoMFA; CoMSIA
Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity
Keywords: مهار کننده های کربن انیدراتا; Multi-target drugs; Dihydrofolate reductase inhibitors; Carbonic anhydrase inhibitors; Cancer therapy;
Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides
Keywords: مهار کننده های کربن انیدراتا; Isoquinolines; Anticonvulsants; DBA/2 mice; Carbonic anhydrase inhibitors
Understanding the Importance of IOP Variables in Glaucoma: A Systematic Review
Keywords: مهار کننده های کربن انیدراتا; adrenergic beta antagonists; carbonic anhydrase inhibitors; glaucoma; intraocular pressure; ocular tonometry; ophthalmologic diagnostic techniques; prostaglandin analogs
A DFT-based quantum theoretic QSAR study of aromatic and heterocyclic sulfonamides as carbonic anhydrase inhibitors against isozyme, CA-II
Keywords: مهار کننده های کربن انیدراتا; Sulfonamides; Carbonic anhydrase inhibitors; Molecular descriptors; QSAR; DFT; AM1
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; Matrix metalloproteinase inhibitors; Hydroxamic acid inhibitors
Degradation and effects of the potential mosquito larvicides methazolamide and acetazolamide in sheepshead minnow (Cyprinodon variegatus)
Keywords: مهار کننده های کربن انیدراتا; Methazolamide; Acetazolamide; Fish; Mosquito larvae; Carbonic anhydrase inhibitors;
Carbonic anhydrase inhibitors: Transepithelial transport of thioureido sulfonamide inhibitors of the cancer-associated isozyme IX is dependent on efflux transporters
Keywords: مهار کننده های کربن انیدراتا; Carbonic anhydrase inhibitors; CAIX; Efflux transporters; Caco-2 cells
Novel use of chemical shift in NMR as molecular descriptor: a first report on modeling carbonic anhydrase inhibitory activity and related parameters
Keywords: مهار کننده های کربن انیدراتا; NMR chemical shift; Carbonic anhydrase inhibitors; Diuretic activity; Lipophilicity; Distance-based topological indices; Regression analysis;