Keywords: CaSR; calcium-sensing receptor; CT; connecting tubules; DCT; distal convoluted tubules; ECaC; epithelial calcium channels; HL; thick limbs of the loop of Henle; IHC; immunohistochemistry; IF; immunofluorescent; MDP; mitochondrial-derived peptides; MOTS-c;
مقالات ISI (ترجمه نشده)
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Keywords: kidney calculi; nephrolithiasis; precision medicine; genetics; hypercalciuria; AKI; acute kidney injury; CaSR; calcium-sensing receptor; CKD; chronic kidney disease; dRTA; distal renal tubular acidosis; ESKD; end-stage kidney disease; HHRH; hereditary hyp
Keywords: CaSR; CKD-MBD; Feline; FGF-23; KASP; Phosphate; PTH;
Keywords: chronic pancreatitis; acute recurrent pancreatitis; PRSS1; SPINK1; CFTR; next-generation sequencing; ATP8B1; ATPase type 8B member 1; CASR; Calcium-sensing receptor; CFTR; Cystic fibrosis transmembrane conductance regulator gene; CLDN2; CLAUDIN 2; CP; Chr
Keywords: HHcy; hyperhomocysteinemia; ECs; endothelial cells; H2S; hydrogen sulfide; CaSR; calcium-sensing receptor; CSE; cystathionine-gamma-lyase; [Ca2+]i; intracellular calcium ion; PIP2; phosphatidylinositol biphosphate; DAG; diacylglycerol; IP3; inositol 1,4,5
Keywords: ACE; angiotensin-converting enzyme; AChE; acetylcholine esterase; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; AP-1; activator protein 1; Aβ; amyloid beta; CaSR; calcium-sensing receptor; COS; chitosan oligosaccharide; COX-2; cyclooxygena
Keywords: AA; amino acid; ADFI; average daily feed intake; ADG; average daily gain; Ala; alanine; ANFs; anti-nutritive factors; Asn; asparagine; Asp; aspartate; CaSR; calcium sensing receptor; CCK; cholecystokinin; CD36; cluster of differentiation 36; dlM; dl-methi
Keywords: AUC; area under the curve; BMI; body mass index; CaSR; calcium sensing receptor; CV; coefficient of variation; DPP-IV; dipeptidyl peptidase-IV; GLP-1; glucagon-like peptide-1; GPCR; G-protein coupled receptor; HV; healthy volunteer; OGTT; oral glucose tol
Keywords: 1,25-D3; 1,25-Dihydroxy vitamin D3; ACF; Aberrant crypt foci; AC; Adenylate cyclase; ADH; Autosomal dominant hypocalcaemia; CaSR; Calcium-sensing receptor; cAMP; Cyclic adenosine 3â²,5â²-monophosphate; Cai2+; Â Intracellular free ionised calcium; Cao2+;
Keywords: ASM; airway smooth muscle; AHR; airway hyperresponsiveness; β2AR; beta 2 adrenergic receptor; BTR; bitter taste receptor; CysLT1R; cysteinyl leukotriene receptor 1; CaSR; calcium sensing receptor; EP; prostanoid EP receptor; GPCR; G protein-coupled recep
Keywords: Ca2Â +; Calcium; PCa; Prostate cancer; RGN; Regucalcin; HCC; hepatocelular carcinoma; [Ca2Â +]o; extracellular Ca2Â + concentration; CaSR; calcium-sensing receptor; Tg-RGN; Sprague Dawley transgenic rats overexpressing RGN; qPCR; Quantitative Real-Time PC
Keywords: Ca2 +; calcium; CRC; colorectal cancer; CaSR; calcium-sensing receptor; PTH; parathyroid hormone; DMEM; Dulbecco's Modified Eagle's Medium; FBS; fetal bovine serum; Zeo; Zeocin; RPLPO; large ribosomal protein; β2M; beta-2-microglobulin; Eef1B2; eukaryot
Keywords: 1,25 (OH)2D; 1,25-dihydroxyvitamin D; ALP; alkaline phosphatase; AVK; vitamin K antagonists; BAX; BCL2-associated X protein; BMDM; bone marrow-derived macrophage; BMP-2; bone morphogenetic protein-2; CAC; coronary artery calcifications; CAD; coronary arte
Keywords: ALN; alendronate; BMD; bone mineral density; BMI; body mass index; CaSR; calcium sensing receptor; CI; confidence interval; DXA; dual-energy X-ray absorptiometry; LSM; least squares means; PBO; placebo; PTH; parathyroid hormone; RONA; ronacaleret; SD; sta
Keywords: PTH; Parathyroid hormone; CaSR; Calcium-sensing receptor; NSHPT; Neonatal severe hyperparathyroidism; Hypercalcemia; Primary hyperparathyroidism; Calcium-sensing receptor; Severe neonatal hyperparathyroidism; Statural defects; Growth plate cartilage;
Keywords: AA; amino acids; BLAST; basic alignment search tool; Ca; calcium; CaSR; calcium sensing receptor; ENaC; epithelial amiloride-sensitive sodium channel; GIT; gastrointestinal tract; GLU; glutamic acid; GLUT2; glucose transporter 2; Na; sodium; NaCl; sodium
Keywords: APC; adenomatous polyposis coli; bFGF; basic fibroblast growth factor; Ca2Â +i; intracellular calcium; Ca2Â +o; extracellular calcium; CaSR; calcium sensing receptor; CDX-2; caudal type homeobox 2; EGF; epidermal growth factor; ERK; extracellular-signal-r
Alterations of DNA methylation in parathyroid tumors
Keywords: Parathyroid tumors; Hyperparathyroidism; PTH; Methylation; Chromatin modifiers; Histones; MEN1; multiple endocrine neoplasia type 1; HPT-JT; hyperparathyroidism- jaw tumors; CpG; cytosine phosphate guanine; 5hmc; 5-hydroxymethylcytosine; TET1; tet (ten-el
Role of nutritional vitamin D in osteoporosis treatment
Keywords: Nutritional vitamin D; Osteoporosis; Hypovitaminosis; Bone turnover; AS; ankylosis spondylosis; BMD; bone mineral density; BMI; body mass index; CaSR; calcium-sensing receptor; CKD; chronic kidney disease; COPD; chronic obstructive pulmonary disease; CT;
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
Important roles of the Ca2+-sensing receptor in vascular health and disease
Keywords: CaSR; Vascular tone; Endothelium; Vascular smooth muscle; Vascular disease;
Role of the Calcium-Sensing Receptor (CaSR) in bovine gametes and during in vitro fertilization
Keywords: IVF; Sperm; Oocyte; Bovine; CaSR; Development;
Vitamin D receptor agonist VS-105 directly modulates parathyroid hormone expression in human parathyroid cells and in 5/6 nephrectomized rats
Keywords: CaSR; calcium-sensing receptor; CKD; chronic kidney disease; NX; nephrectomized; PTH; parathyroid hormone; SHPT; secondary hyperparathyroidism; VDR; vitamin D receptor; VDRA; vitamin D receptor activator or VDR agonist; PTH; Vitamin D receptor; Vitamin D
MicroRNAs in parathyroid physiopathology
Keywords: Parathyroid tumors; Hyperparathyroidism; PTH; miRNAs; C19MC; C19MC; chromosome 19 microRNA cluster; miR-372; microRNA-372; CDKN1A; cyclin-dependent kinase inhibitor 1A; TBX1; T-box 1; GCM2; glial cell missing 2; PTH; parathormone; CCND1; cyclin D1; CASR;
A novel whey tetrapeptide IPAV reduces interleukin-8 production induced by TNF-α in human intestinal Caco-2 cells
Keywords: CaSR; calcium sensing receptor; ESI; electric spray ionization; HPLC; high-performance liquid chromatography; IBD; inflammatory bowel disease; IL; interleukin; ERK; extracellular signal-regulated kinase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; JN
Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced nitric oxide production and vasorelaxation in rabbit mesenteric arteries
Keywords: CaSR; calcium-sensing receptors; EC; endothelial cell; IKCa; intermediate conductance calcium-activated potassium channels; NO; nitric oxide; TRPV4; transient receptor potential vanilloid-4; TRPC1; canonical transient receptor potential channel 1;
The role of vitamin D in the endocrinology controlling calcium homeostasis
Keywords: Absorption; Excretion; Homeostasis; Parathyroid hormone; Endocrinology; 1,25(OH)2 D; 1,25 dihydroxyvitamin D; 25OH D; 25 hydroxyvitamin D; CaSR; calcium sensing receptor; CYP24A1; 25 hydroxyvitamin D, 24 hydroxylase; CYP27B1; 25 hydroxyvitamin D, 1α hydr
Full Length ArticleCalcium-sensing receptor-ERK signaling promotes odontoblastic differentiation of human dental pulp cells
Keywords: CaSR; L-VDCC; HDPC; Odontoblastic differentiation; ERK 1/2;
The effects of RAMPs upon cell signalling
Keywords: Receptor activity modifying protein; G protein-coupled receptor; Signalling; Trafficking; Coupling; AM; adrenomedullin; AMY; amylin; CaSR; calcium-sensing receptor; CGRP; calcitonin gene-related peptide; CHO; chinese hamster ovary; CLR; calcitonin recepto
Association of calcitonin receptor gene (CALCR) polymorphism with kidney stone disease in the population of West Bengal, India
Keywords: KSD; kidney stone disease; CALCR; calcitonin receptor; CaSR; calcium sensing receptor; VDR; vitamin D receptor; CLDN14; claudin 14; SNP; single nucleotide polymorphism; BMI; body mass index; PCR; polymerase chain reaction; dNTP; deoxyribo nucleotide tri-p
Increasing extracellular Ca2 + sensitizes TNF-alpha-induced vascular cell adhesion molecule-1 (VCAM-1) via a TRPC1/ERK1/2/NFκB-dependent pathway in human vascular endothelial cells
Keywords: CaSR; calcium-sensing receptor; CVDs; cardiovascular diseases; [Ca2 +]ex; extracellular Ca2 + concentration; ERK1/2; extracellular signal-regulated kinase 1/2; IκB; inhibitor of κB; IL; interleukin; [Ca2 +]i; intracellular calcium concentration; IKK;
Molecular insights into allosteric modulation of Class C G protein-coupled receptors
Keywords: GABAB; γ-aminobutyric acid receptor B; BMD; bone mass and density; CaSR; calcium-sensing receptor; CHO; Chinese hamster ovary; CRD; cysteine-rich domain; ER; endoplasmic reticulum; Ca2+o; extracellular calcium; pERK1/2; extracellular signal-regulated kin
Src-family tyrosine kinases and the Ca2Â + signal
Keywords: 5-HT6; serotonin receptor 6; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid; ADPR; ADP-ribose; AMPA; α-amino-3-hydr
Neonatal severe hyperparathyroidism caused by homozygous mutation in CASR: A rare cause of life-threatening hypercalcemia
Keywords: Neonatal severe hyperparathyroidism; CASR; Calcimimetic; Exome dataNSHPT, Neonatal severe hyperparathyroidism; CaSR, Calcium-sensing receptor; PTH, Parathyroid hormone; TRPS1, Trichorhinophalangeal syndrome I
Strontium (Sr) elicits odontogenic differentiation of human dental pulp stem cells (hDPSCs): A therapeutic role for Sr in dentine repair?
Keywords: Strontium (Sr); Human dental pulp stem cells (hDPSCs); Odontogenic differentiation; Dentine sialophosphoprotein (DSPP); Dentine matrix protein 1 (DMP-1); bioactive glass (BG); Dentine; CaSR; MAPK/ERK
Original ArticleKeratinocytes/EpidermisIntegrin-Linked Kinase Is Indispensable for Keratinocyte Differentiation and Epidermal Barrier Function
Keywords: [Ca2+i]; intracellular Ca2+ concentration; [Ca2+o]; extracellular Ca2+ concentrations; CaSR; calcium sensing receptor; DIC; differential interference contrast; Dsg4; desmoglein 4; ILK; integrin-linked kinase;
Calcium sensing receptor suppresses human pancreatic tumorigenesis through a novel NCX1/Ca2+/β-catenin signaling pathway
Keywords: CaSR; Pancreatic cancer; Ca2+ signaling; NCX1; β-cateninCaSR, calcium sensing receptor; NCX1, Na+/Ca2+ exchanger 1; [Ca2+]cyt, cytosolic Ca2+; GPCR, G protein-coupled receptor; PC, pancreatic cancer; CRC, colorectal cancer
Interplay between CaSR and PTH1R signaling in skeletal development and osteoanabolism
Keywords: 1,25D; 1,25-dihydroxyvitamin D; Agg; aggregan; ALP; alkaline phosphatase; BRU; bone remodeling unit; CaSR; extracellular calcium-sensing receptor; [Ca2+]e; extracellular calcium concentration; Col(I); type I collagen; α1(I); alpha 1 subunit of the type I
Calcium-sensing-receptor (CaSR) controls IL-6 secretion in metastatic breast cancer MDA-MB-231Â cells by a dual mechanism revealed by agonist and inverse-agonist modulators
Keywords: CaSR; IL-6-secretion; GPCR; Cell signaling; Breast cancer; Traffic;
Modulatory effects of l-arginine and soy enriched diet on bone homeostasis abnormalities in streptozotocin-induced diabetic rats
Keywords: ALP; alkaline phosphatase; BMP-2; bone morphogenetic protein 2; CaSR; calcium sensing receptor; CTX; C-terminal telopeptides of type I collagen; DM; diabetes mellitus; Dlx5; distal less gene; EGF; epidermal growth factor; ERβ; estrogen receptor β; FGF23
Effects of supplemental vitamin D and calcium on normal colon tissue and circulating biomarkers of risk for colorectal neoplasms
Keywords: CaSR; calcium sensing receptor; CRP; C-reactive protein; ELISA; enzyme-linked immunoassay; 8-OH-dG; 8-hydroxy-deoxyguanosine; IL; interleukin; MMR; mismatch repair; RONS; reactive oxygen and nitrogen species; TGF; transforming growth factor; VDR; vitamin
γ-Glutamyl cysteine and γ-glutamyl valine inhibit TNF-α signaling in intestinal epithelial cells and reduce inflammation in a mouse model of colitis via allosteric activation of the calcium-sensing receptor
Keywords: CaSR; calcium-sensing receptor; GPCR; G-protein-coupled receptor; IBD; inflammatory bowel disease; CD; Crohn's disease; UC; ulcerative colitis; γ-EC; γ-glutamyl cysteine; γ-EV; γ-glutamyl valine; GRK; GPCR kinase; TRAF; TNF-receptor-associated factor;
Role of post-translational modifications on structure, function and pharmacology of class C G protein-coupled receptors
Keywords: GPRC6A; CaSR; mGluR; Post-translational modifications; Glycosylation; Phosphorylation; Ubiquitination; Palmitoylation;
Translating Molecular Physiology of Intestinal Transport Into Pharmacologic Treatment of Diarrhea: Stimulation of Na+ Absorption
Keywords: Diarrhea; Na Absorption; Intestine; BB; brush border; CaSR; calcium-sensing receptor; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; DRA; down-regulated in adenoma; ENaC; epithelial Na+ channel; GI; gastrointestinal; NHE3; sod
Quantitative investigation of calcimimetic R568 on beta cell adhesion and mechanics using AFM single-cell force spectroscopy
Keywords: AFM-SCFS; Cell adhesion; Indentation; Elasticity; CaSR; Calcimimetic
Diagnosis and classification of autoimmune parathyroid disease
Keywords: 21-OHAbs; 21-hydroxylase antibodies; AD; Addison's disease; ACA; adrenal cortex antibodies; AADC; aromatic l-amino acid decarboxylase autoantibodies; APS-1; autoimmune polyendocrine syndrome type 1; AIRE; AutoImmune REgulator; CaSR; calcium-sensing recept
AXT914 a novel, orally-active parathyroid hormone-releasing drug in two early studies of healthy volunteers and postmenopausal women
Keywords: AE; adverse event; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUCtau; area under the time versus blood level curve in one dosing interval; BMD; bone mineral density; CaSR; calcium-sensing receptor; Cmax; maximum (peak) concentration;
Roles of intraloops-2 and -3 and the proximal C-terminus in signalling pathway selection from the human calcium-sensing receptor
Keywords: GPCR; G-protein coupled receptor; CaSR; calcium-sensing receptor; PI-PLC; phosphatidylinositol-specific phospholipase-C; VFT; Venus FlyTrap; CR; Cysteine-rich; iL; intraloop; cAMP; adenosine 3â²,5â²-cyclic monophosphate; pERK; phosphorylated extracellul
The vitamin D system is deregulated in pancreatic diseases
Keywords: VDR; vitamin D receptor; CYP24A1; 1,25-dihydroxyvitamin D3 24-hydroxylase; CaSR; calcium-sensing receptor; 1,25(OH)2D3; 1,25-dihydroxyvitamin D3; CYP27B1; 25-hydroxyvitamin D3 1α-hydroxylase; VDRE; vitamin D response elements; PDAC; pancreatic ductal ade
Pharmacoperones and the calcium sensing receptor: Exogenous and endogenous regulators
Keywords: ADH; autosomal dominant hypocalcemia; CaSR; calcium sensing receptor; xCT; cystine-glutamate transporter; DHPs; dihydropyridines; EAAT; excitatory amino acid transporter; EGFR; endothelial growth factor receptor; ER; endoplasmic reticulum; ERK1/2; extrace