دانلود مقالات ISI درباره Cyp + ترجمه فارسی

Beyond vitamin E supplementation: An alternative strategy to improve vitamin E status

Keywords: Blood plasma; Carboxyethyl hydroxychromanols; Humans; Liver; Metabolites; Rats; Tocopherols; Vitamin E status; BHT; butylated hydroxytoluene; CEHC; carboxyethyl hydroxychromanol; CYP; cytochrome P450; T; tocopherol; α-TTP; α-tocopherol transfer protein;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Role of specific protein kinase C isoforms in modulation of β1- and β2-adrenergic receptors

Keywords: Signalling; G protein-coupled receptors; Desensitization; Protein kinase; α1BAR; α1B-adrenergic receptor; CA; constitutively active; CYP; cyanopindolol; βAR; β-adrenergic receptor; βARK; β-adrenergic receptor kinase; GPCR; G protein-coupled receptor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Involvement of SULT1A3 in elevated sulfation of 4-hydroxypropranolol in Hep G2 cells pretreated with β-naphthoflavone

Keywords: BNF; β-naphthoflavone; CYP; cytochrome P450; 4-OH-BTL; 4-hydroxybunitrolol; DHEA; dehydroepiandrosterone; 4-OH-PL; 4-hydroxypropranolol; IPTG; isopropyl-β-d-thiogalactopyranoside; NDP; N-desisopropyl propranolol; PL; propranolol; PVDF; polyvinylidene di

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: Correlation study with induction in vivo

Keywords: AhR; aryl hydrocarbon receptor; CAR; constitutive androstane receptor; CYP; cytochrome P450; HPBCD; hydroxypropyl-β-cyclodextrin; MGB; minor groove binding; NCEs; new chemical entities; PAHs; polycyclic aromatic hydrocarbons; PB; phenobarbital; PCN; preg

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Complementary Stimulation of Hepatobiliary Transport and Detoxification Systems by Rifampicin and Ursodeoxycholic Acid in Humans

Keywords: 4β-OH-C; 4β-hydroxy cholesterol; BAAT; bile acid amino transferase; BSEP; bile salt export pump; C4; 7α-hydroxy-4-cholesten-3-one; CA; cholic acid; CYP; cytochrome P450; DCA; deoxycholic acid; HCA; hyocholic acid; LCA; lithocholic acid; CDCA; chenodeox

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Recent advances in the bioremediation of persistent organic pollutants via biomolecular engineering

Keywords: Persistent organic pollutants; Biomolecular engineering; Bioremediation; Directed evolution; Bph; biphenyl dioxygenase; CB; chlorobiphenyls; CBA; (chloro)benzoate; CYP; cytochrome P450 monooxygenase; GEM; genetically engineered microorganism; IVC; in vitr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay

Keywords: Cytochrome P450; CYP; In vitro cocktail; Inhibition; LC/MS; Human liver microsomes;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Induction of hepatic drug-metabolising enzymes and tamoxifen metabolite profile in relation to administration route during low-dose treatment in nude rats

Keywords: Tamoxifen; Cytochrome P450; CYP; Enzyme induction; Pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Expression of Nuclear Receptor and Target Genes in Liver and Intestine of Neonatal Calves Fed Colostrum and Vitamin A

Keywords: nuclear receptor; retinoic acid; cytochrome P450; neonatal calves; CAR; constitutive androstane receptor; CO; colostrum-fed group; CYP; cytochrome p450; FA; formula plus vitamin A-fed group; FO; formula-fed group; LRAT; lecithin: retinol acyltransferase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Hepatoprotective mechanisms of Yan-gan-wan

Keywords: YGW; Yan-gan-wan; CYP; cytochrome P450; LPS; lipopolysaccharide; TNFα; tumor necrosis factor α; RT-PCR; reverse transcription-polymerase chain reaction; RNA; ribonucleic acid; cDNA; complimentary deoxyribonucleic acid; CCl4; carbon tetrachloride; ALT; a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

CYP superfamily perturbation by diflubenzuron or acephate in different tissues of CD1 mice

Keywords: Acephate; Diflubenzuron; CYP; Testosterone hydroxylase; Pesticides;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Gene-inducing program of human dendritic cells in response to BCG cell-wall skeleton (CWS), which reflects adjuvancy required for tumor immunotherapy

Keywords: ADA; adenosine deaminase; ANOVA; analysis of variance; AP-1; activating protein-1; BCG-CWS; bacillus Calmette-Guérin cell-wall skeleton; BIGM103; BCG-induced gene in monocyte, clone 103; CCL; chemokine (C-C motif) ligand; CD; cluster of differentiation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Intestinal metabolism of PAH: in vitro demonstration and study of its impact on PAH transfer through the intestinal epithelium

Keywords: Caco-2 cells; PAH; Intestinal transfer; Metabolism; BaP; benzo[a]pyrene; BDM; basal defined medium; CYP; cytochrome; DMSO; dimethylsulfoxide; EGF; epidermal growth factor; FCS; fetal calf serum; PAHs; polycyclic aromatic hydrocarbons; Phe; phenanthrene; P

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Acetaminophen decreases intracellular glutathione levels and modulates cytokine production in human alveolar macrophages and type II pneumocytes in vitro

Keywords: APAP; acetaminophen; CYP; cytochrome P450; DDTC; diethyldithiocarbamic acid; DMEM; Dulbecco's modified Eagle's medium; DNase; deoxyribonuclease; FBS; fetal bovine serum; GSH; reduced glutathione; PGHS; prostaglandin H synthetase; IL-6; interleukin 6; IL-8

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Regulation of Bcl-2 and Bcl-xL anti-apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes

Keywords: AS; antisense oligonucleotides; CELL; non-treated control-cells; CLO; clotrimazole; CYP; cytochrome P450; DEX; dexamethasone; FBS; foetal bovine serum; GST; glutathione S-transferase; MDR1; multidrug resistance-1; MP; metyrapone; MRP; multidrug resistance

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Transport of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide by human intestinal Caco-2 cells

Keywords: ACSRC; Auckland Cancer Society Research Centre; AP; apical; BL; basolateral; CYP; cytochrome P450; DMSO; dimethyl sulphoxide; DMXAA; 5,6-dimethylxanthenone-4-acetic acid; DMXAA-G; DMXAA acyl glucuronide; HBSS; Hanks' balanced salt solution; HEPES; N-[2-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Induction of phase-1 metabolizing enzymes by oltipraz, flavone and indole-3-carbinol enhance the formation and transport of benzo[a]pyrene sulfate conjugates in intestinal Caco-2 cells

Keywords: ABC; ATP-binding cassette; AhR; aryl hydrocarbon receptor; BP; benzo[a]pyrene; 3-OH-BP; 3-hydroxybenzo[a]pyrene; INF; indeno[1,2,3-cd]fluoranthene; 3-MC; 3-methylcholanthrene; β-NF; β-naphthoflavone; CYP; cytochrome P450; DMSO; dimethylsulfoxide; GST; g

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

CYP1A1 and CYP1B1 genotypes, haplotypes, and TCDD-induced gene expression in subjects from Seveso, Italy

Keywords: EROD; ethoxyresorufin-O-deethylase; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; CYP; cytochrome P450; LD; linkage disequilibrium; AhR; aryl hydrocarbon receptor; SNP; single nucleotide polymorphisms; ppt; parts per trillion; RT-PCR; reverse transcription p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Histomorphological changes and cytochrome P450 isoforms expression and activities in precision-cut liver slices from neonatal rats

Keywords: BNF; β-naphthoflavone; BSA; bovine serum albumin; CYP; cytochrome P450; DEX; dexamethasone; DMSO; dimethylsulfoxide; ECOD; ethoxycoumarin O-deethylation; EROD; ethoxyresorufin O-deethylation; HE; hematoxylin and eosin; PAS; periodic acid-Schiff; PB; phen

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

CYP2K6 from zebrafish (Danio rerio): Cloning, mapping, developmental/tissue expression, and aflatoxin B1 activation by baculovirus expressed enzyme

Keywords: AFB1; Aflatoxin B1; BSA; Bovine serum albumin; Bv-2K6; Baculovirus/insect cell expressed recombinant CYP2K6; CYP; Cytochrome P450; EST; Expressed sequence tag; GSH; Glutathione; HPLC; High pressure liquid chromatography; LC-MS; Liquid chromatography-mass

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Kinetics of tienilic acid bioactivation and functional generation of drug-protein adducts in intact rat hepatocytes

Keywords: CYP; cytochrome P 450; l-NAME; NG-nitro-l-argininine methyl ester; TA; 2,3-dichloro 4-(2-thienyl carbonyl) phenoxyacetic acid, tienilic acid; TBS; 50 mM Tris-HCl/150 mM KCl/1 mM EDTA buffer, pH 7.4; Primary cultured hepatocytes; CYP; Tienilic acid; D

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species

Keywords: ASA; acetylsalicylic acid; ATM; ataxia telangiectasia mutated; COX; cyclooxygenase (PHS component); CYP; cytochromes P450; ETYA; eicosatetraynoic acid; G6PD; glucose-6-phosphate dehydrogenase; GSH; glutathione; iNOS; inducible nitric oxide synthase; IR; i

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics

Keywords: BSO; l-buthionine S,R-sulphoximine; CYP; cytochrome P450; DMEM; Dulbecco's Modified Eagle's Medium; DMSO; dimethyl-sulphoxide; GSH: reduced glutathione; MTT; 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl tetrazolium bromide; PBS; phosphate buffered saline; M

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review

Keywords: ADI; acceptable daily intake; BMD; benchmark dose; CSAF; chemical-specific adjustment factor; LOAEL; low observed adverse effect level; NOAEL; no observed adverse effect level; RfD; reference dose; TDI; tolerable daily intake; AUC; area under the plasma-c

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

PCB profiles in mouse skin biopsies and fat from an environmental mixture

Keywords: AhR; aryl hydrocarbon receptor; CYP; cytochrome P-450; GC; gas chromatography; GC-MS; GC-mass spectrometry; μ-ECD; micro electron capture detector; PCA; polychlorinated aromatic; PCBs; polychlorinated biphenyls; PCDDs; polychlorinated dibenzo-p-dioxi

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity

Keywords: 1,2-OHCHN; 1,2-dihydroxy-chrysene; 1-OHBaP; 1-hydroxy-benzo[a]pyrene; 1-OHCHN; 1-hydroxy-chrysene; 7,8-OHBaP; 7,8-dihydroxy-benzo[a]pyrene; 7,8-OH-H2BaP; trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene; AhR; aryl hydrocarbon receptor; BaP; benzo[a]pyrene; B

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach

Keywords: Lung; Pulmonary toxicity; CYP; Bioactivation; A549 cells;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه

Toxicogenomic analysis of gene expression changes in rat liver after a 28-day oral benzene exposure

Keywords: Ah; aryl hydrocarbon; Alas2; aminolevulinic acid synthase 2; CO; control; Cyp; cytochrome P450 enzyme; G6pc; glucose-6-phosphatase; G6pd; glucose-6-phosphate dehydrogenase; GSH; glutathione; Gst; glutathione-S-transferase; Hnf; hepatic nuclear factor; Hnf

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2005 سفارش ترجمه

On the mechanism of biosynthesis of 19-hydroxyprostaglandins of human seminal fluid and expression of cyclooxygenase-2, PGH 19-hydroxylase (CYP4F8) and microsomal PGE synthase-1 in seminal vesicles and vas deferens

Keywords: Carbaprostacyclin; Co-localization; Hydroxyprostaglandin; Immunohistochemistry; Real-time PCR; Liquid chromatography-mass spectrometry; COX; cyclooxygenase; CYP; cytochrome P450; ER; endoplasmic reticulum; 6,9α-Methylene-PGI2; carbaprostacyclin; 9α,11α

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2005 سفارش ترجمه

Role of cell signaling in B[a]P-induced apoptosis: characterization of unspecific effects of cell signaling inhibitors and apoptotic effects of B[a]P metabolites

Keywords: α-NF; α-naphthoflavone; AHR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; B[a]P-4,5-DHD; (±)-benzo[a]pyrene-trans-4,5-dihydrodiol; B[a]P-7,8-DHD; (±)-benzo[a]pyrene-trans-7,8-dihydrodiol; B[a]P-9,10-DHD; (±)-benzo[a]pyrene-trans-9,10-dihydrodiol

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2005 سفارش ترجمه

Polymorphisms affecting gene regulation and mRNA processing: Broad implications for pharmacogenetics

Keywords: 5-FU; 5-fluorouracil; 5-HTT; serotonin transporter; 5-HTTLPR; serotonin gene-linked polymorphic region; 6-MP; 6-mercaptopurine; 6-TG; 6-thioguanine; ABCB; ATP-binding cassette (ABC), subfamily B; ACE; angiotensin I converting enzyme (peptidyl-dipeptidase

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2005 سفارش ترجمه

NADPH-dependent metabolism of 17β-estradiol and estrone to polar and nonpolar metabolites by human tissues and cytochrome P450 isoforms

Keywords: E2; 17β-estradiol; E1; estrone; OH; hydroxy; CYP; cytochrome P450; NADPH; β-nicotinamide adenine dinucleotide phosphate (reduced form); HPLC; high-performance liquid chromatography; GC/MS; gas chromatography/mass spectrometry; TMS; trimethylsilyl; pmol/

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2005 سفارش ترجمه

Pharmacogenetics for individualized cancer chemotherapy

Keywords: Cancer drug resistance; Single nucleotide polymorphisms; Toxicity; ABC transporter; ATP-binding cassette transporter; BCRP; breast cancer-related protein; CDA; cytidine deaminase; CYP; cytochrome P450 monoxigenase; DPYD; dihydropyrimidine dehydrogenase; E

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2005 سفارش ترجمه

Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism

Keywords: Flavin monooxygenase; Drug metabolism; FMO; BVMOs; Baeyer-Villiger monooxygenases; CYP; cytochrome P450; DBM; dinucleotide-binding motif; FADPNR; FAD-dependent pyridine nucleotide reductase PRINTS signature; FMO; flavin-containing monooxygenase; FMOXYGE

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2005 سفارش ترجمه