دانلود مقالات ISI درباره دیلی + ترجمه فارسی

Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism

Keywords: دیلی; CYP; cytochrome P450; CYP-reductase; NADPH cytochrome P450 reductase; DCF-AG; diclofenac acyl glucuronide; DCF-SG; diclofenac glutathione conjugate; DILI; drug-induced liver injury; ESI; electrospray ionization; GST; glutathione S-transferase; GWAS; genom

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes

Keywords: دیلی; Ac-DEVD-AMC; N-acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin; AKT; protein kinase B; AMP; ampicillin; ATB; antibiotic; ATF6; activating transcription factor 6; BC; bile canaliculi; BSEP; bile salt export pump; CDF; 5(6)-carboxy-2,7-dichlorofluorescein;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Herbal and Dietary Supplement-Induced Liver Injuries in the Spanish DILI Registry

Keywords: دیلی; Hepatotoxicity; Clinical Presentation; Herbal Signature; Re-challenge; AAS; anabolic androgenic steroids; ALF; acute liver failure; ALP; alkaline phosphatase; ALT; alanine transaminase; AST; aspartate aminotransferase; CAM; complementary and alternative m

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Genetic determinants of cholangiopathies: Molecular and systems genetics

Keywords: دیلی; AP; alkaline phosphatase; ASBT; apical sodium bile acid transporter; BRIC; benign recurrent intrahepatic cholestasis; CC; collaborative cross; DILI; drug-induced liver injury; É£-GT; É£-glutamyl transpeptidase; GRP; genetic reference populations; GWAS; ge

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Bioengineered Liver Models for Drug Testing and Cell Differentiation Studies

Keywords: دیلی; Microfluidics; Hepatocytes; Micropatterned Co-Cultures; Spheroids; Bioprinting; Cellular Microarrays; BAL; bioartificial liver; CRP; C-reactive protein; CYP450; cytochrome P450; DILI; drug-induced liver injury; ECM; extracellular matrix; HSC; hepatic stel

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Individual serum bile acid profiling in rats aids in human risk assessment of drug-induced liver injury due to BSEP inhibition

Keywords: دیلی; ALT; alanine amino transferase; AST; aspartate amino transferase; AUClast; area under the plasma time curve from time 0 to the last measured concentration (24 h); BSEP; Bile Salt Export Pump; CL; clearance; C0; highest initial plasma concentration of dru

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Cell-based assay using glutathione-depleted HepaRG and HepG2 human liver cells for predicting drug-induced liver injury

Keywords: دیلی; AUC; area under receiver operating characteristic curve; BSO; L-buthionine-S,R-sulfoximine; BW; boxed warning; Cmax; therapeutic maximum plasma concentration; CYP; cytochrome P450; DILI; drug-induced liver injury; DMSO; dimethyl sulfoxide; FBS; fetal bovi

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Comparative hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice

Keywords: دیلی; Fasiglifam (TAK-875); Drug-induced liver injury (DILI); Microarray; Comparative hepatic transcriptome analysis; Gene set enrichment analysis; ALT; Alanine aminotransferase; Bsep; Bile salt export pump; CCl4; Carbon tetrachloride; ConA; Concanavalin A; DAM

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro™ (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments

Keywords: دیلی; Cardiotoxicity; Herbal-induced liver injury; Hepatotoxicity; New dietary ingredient; OXYElite pro; Phytochemicals; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; DILI; drug-induced liver injury; DILIN; Drug-Induced Li

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity

Keywords: دیلی; Mitochondria; Drug-induced liver injury; HepaRG; Seahorse; Glucose/galactose; Bioenergetic phenotype; ALR; ATP-linked respiration; BCA; bicinchoninic Acid; BR; basal respiration; CCCP; cyanide m-chlorophenyl hydrazine; CPT; carnitine palmitoyl transferase

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2018 سفارش ترجمه

INASL Position Statements on Prevention, Diagnosis and Management of Hepatitis B Virus Infection in India: The Andaman Statements

Keywords: دیلی; AASLD; American Association for the Study of Liver Diseases; ADV; adefovir dipivoxil; ALT; alanine aminotransferase; Anti-HBe; antibodies to hepatitis B envelope antigen; anti-HBs; antibody to hepatitis B surface antigen; APASL; Asian Pacific Association

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2018 سفارش ترجمه

Serum microRNA-122-3p, microRNA-194-5p and microRNA-5099 are potential toxicological biomarkers for the hepatotoxicity induced by Airpotato yam

Keywords: دیلی; miRNAs; microRNAs; ALT; alanine transaminase; AST; aspartate transaminase; EF; ethyl acetate fraction of Airpotato yam; DB; diosbulbin B; APAP; acetaminophen; MCT; monocrotaline; TSN; toosendanin; DILI; Drug-induced liver injury; WHO; World Health Organiz

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury

Keywords: دیلی; BP; biological process; CPDB; ConsensusPathDB; DEG; differentially expressed gene; DILI; drug-induced liver injury; FDR; false discovery rate; GO; gene ontology; I; idiosyncratic compound; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; N

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The assessment of the chronic hepatotoxicity induced by Polygoni Multiflori Radix in rats: A pilot study by using untargeted metabolomics method

Keywords: دیلی; TCM; Traditional Chinese Medicine; HSW; He-Shou-Wu; DILI; Drug-Induced Live Injury; NAFLD; Non-Alcoholic Fatty Liver Disease; LC-MS; Liquid-Chromatography-Tandem Mass Spectrometry; GC-MS; Gas Chromatography-Mass Spectrometry; TSG; 2,3,5,4′-tetrahydr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Attenuation of thioacetamide-induced hepatocellular injury by short-term repeated injections associated with down-regulation of metabolic enzymes and relationship with MHC class II-presenting cells

Keywords: دیلی; DILI; Damage-associated molecular patterns; Flavin monooxygenase 3; Thioacetamide; Rat model; Repeated injections;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The role of microRNAs in liver injury at the crossroad between hepatic cell death and regeneration

Keywords: دیلی; Liver disease; Fatty liver; Apoptosis; miRNA; Plasticity; Dedifferentiation; ALF; Acute liver failure; DILI; Drug-induced liver injury; EMT; Epithelial-mesenchymal transition; HCC; Hepatocellular carcinoma; HCV; Hepatitis C virus; NAFLD; Non-alcoholic fat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

Keywords: دیلی; Medication; Liver Damage; Side Effect; Anti-Fungal Agent; AF; allele frequency; CM; cholestatic-mixed; DILI; drug-induced liver injury; DILIN; Drug-Induced Liver Injury Network; GWAS; genome-wide association study; HC; hepatocellular; iDILIC; Internationa

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Safety assessment of the dietary supplement OxyELITE™ Pro (New Formula) in inbred and outbred mouse strains

Keywords: دیلی; Dietary supplements; Drug-induced liver injury; Hepatotoxicity; Phytochemicals; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; DILI; drug-induced liver injury; DILIN; Drug-Induced Liver Injury Network; DMAA; 1,3-dimet

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

3D in vitro models of liver fibrosis

Keywords: دیلی; HSCs; hepatic stellate cells; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aminotransferase; CBDL; common biled duct ligation; DAMPs; damage associated molecular patterns; DCM; decellularized matrix; DILI; drug-induced liver injury; ECM; extra

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of Bile Acids Responsible for Inhibiting the Bile Salt Export Pump, Leading to Bile Acid Accumulation and Cell Toxicity in Rat Hepatocytes

Keywords: دیلی; biliary excretion; in vitro models; toxicology; bile acid transporters; efflux pumps; BA; bile acid; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; CsA; cyclosporin A; DCA; deoxycholic acid; DILI; drug-induced liver injury; DM

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Rifampicin-induced injury in HepG2 cells is alleviated by TUDCA via increasing bile acid transporters expression and enhancing the Nrf2-mediated adaptive response

Keywords: دیلی; RFP; rifampicin; TUDCA; tauroursodeoxycholic acid; Nrf2; nuclear factor erythroid 2-related factor; DILI; drug-induced liver injury; ALF; acute liver failure; TB; tuberculosis; INH; isoniazid; GSH; glutathione; BAs; bile acids; ER; endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Sertraline-Associated Cholestasis and Ductopenia Consistent with Vanishing Bile Duct Syndrome

Keywords: دیلی; DILI; Drug-induced liver injury; SSRI; Selective serotonin reuptake inhibitor; VBDS; Vanishing bile duct syndrome;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

The kinetics of damage-associated molecular patterns (DAMPs) and toll-like receptors during thioacetamide-induced acute liver injury in rats

Keywords: دیلی; DILI; DAMPs; Thioacetamide; TLRs;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

High content analysis assay for prediction of human hepatotoxicity in HepaRG and HepG2 cells

Keywords: دیلی; DILI; drug-induced liver injury; GLP; good laboratory practice; HCA; high content analysis; ROS; reactive oxygen species; GSH; glutathione; MMP; mitochondrial membrane potential; MP; membrane permeability; CM-H2DCFDA; 5-(and-6)-chloromethyl-2′,7′-dich

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatopatías de origen tóxico y farmacológico

Keywords: دیلی; Hepatotoxicidad; Daño hepático; CausalidadHepatotoxicity; DILI; Causality

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Exosomes in liver pathology

Keywords: دیلی; CCA; cholangiocarcinoma; DILI; drug-induced liver injury; EV; extracellular vesicle; MVBs; multivesicular bodies; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; IFN; interferon; LPS; lipopolysaccharide; miRNA; microRNA; MSC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Caffeic acid attenuated acetaminophen-induced hepatotoxicity by inhibiting ERK1/2-mediated early growth response-1 transcriptional activation

Keywords: دیلی; Caffeic acid; Acetaminophen; Hepatotoxicity; Detoxification; Egr1; ERK1/2; ALT/AST; alanine/aspartate aminotransferase; CA; caffeic acid; CYP450; cytochrome P450; DILI; Drug-induced liver injury; Egr1; early growth response1; ELISA; Enzyme-linked immunoso

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse

Keywords: دیلی; Bile salt export pump; BSEP; ABCB11; Drug-induced liver injury; DILI; Bile salts; Hepatocytes; Species differenceBSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; DILI, drug-induced liver injury; GCA, glycocholic acid; GCDCA, glyc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries

Keywords: دیلی; Hepatotoxicity; DILI; Idiosyncratic hepatotoxicity; Individual differences; Risk factors; P450; CYP3A4; Acetaminophen; Cyclophosphamide; Ketoconazole; Tamoxifen; Human hepatocytes

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Establishment of a Drug-Induced, Bile Acid-Dependent Hepatotoxicity Model Using HepaRG Cells

Keywords: دیلی; hepatocytes; bile acid transporters; biliary excretion; in vitro models; toxicology; cell lines; ALP; alkaline phosphatase; BA; bile acid; BEI; biliary excretion index; BSEP/Bsep; bile salt export pump; CsA; cyclosporine A; DILI; drug-induced liver injur

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes

Keywords: دیلی; DILI; Liver; Nevirapine; Ritonavir; Transcriptomics; 3-D models

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Drug-induced cholestasis risk assessment in sandwich-cultured human hepatocytes

Keywords: دیلی; BAs; bile acids; Cmax; maximum plasma concentration; CDF(DA); 5-(6)-carboxy-2′,7′-dichlorofluorescein (diacetate); DIC(I); drug-induced cholestasis (index); DILI; drug-induced liver injury; IMI; Innovative Medicine Initiative; MIP-DILI; Mechanism-Base

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Reviews and feature articleNew approaches for predicting T cell-mediated drug reactions: A role for inducible and potentially preventable autoimmunity

Keywords: دیلی; T cell; adverse drug reaction; autoimmunity; ADR; Adverse drug reaction; DILI; Drug-induced liver disease; DRESS; Drug reaction with eosinophilia and systemic symptoms; GAD; Glutamic acid decarboxylase; OR; Odds ratio; SJS; Stevens-Johnson syndrome; SLE;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleProtective effect of Th22 cells and intrahepatic IL-22 in drug induced hepatocellular injury

Keywords: دیلی; AHB; acute hepatitis B; ALT; alanine aminotransferase; AIH; autoimmune hepatitis; CHB; chronic hepatitis B; CK 7; cytokeratin 7; DILI; drug induced liver injury; HAI; histological activity index; IL-22; interleukin-22; IL-17; interleukin-17; NSAIDs; non-s

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Drug biokinetic and toxicity assessments in rat and human primary hepatocytes and HepaRG cells within the EU-funded Predict-IV project

Keywords: دیلی; AMI; amiodarone; ADR; adverse drug reaction; CPZ; chlorpromazine; CsA; cyclosporine A; CYP; cytochrome P450-dependent monooxygenases; DICI; Drug Induced Cholestasis Index; DILI; drug-induced liver injury; DME; drug metabolizing enzyme; IBU; ibuprofen; NSA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children

Keywords: دیلی; miRNA; microRNA; DILI; drug induced liver injury; APAP; acetaminophen; ALT; alanine aminotransferase; ALF; acute liver failure; Acetaminophen; Pediatric; Urine; MicroRNA; DILI;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death

Keywords: دیلی; ADR; adverse drug reaction; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; DILI; drug-induced liver injury; ETC; electron transport chain; EC50-ATP; drug concentration which decreases cellular ATP level by 50%; EC150-CT; drug concentration which increas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatitis E Virus Infection as a Possible Cause of Acute Liver Failure in Europe

Keywords: دیلی; Liver Disease; Hepatitis E; Blood Test; Diagnosis; ALF; acute liver failure; ALT; alanine aminotransferase; AST; aspartate aminotransferase; DILI; drug-induced liver injury; ELT; emergency liver transplantation; GVHD; graft-versus-host disease; HEV; hepat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Comedications alter drug-induced liver injury reporting frequency: Data mining in the WHO VigiBase™

Keywords: دیلی; ACEI; angiotensin converting enzyme inhibitor; ADE; adverse drug events; AERS; adverse event reporting system; APAP; acetaminophen; ATC classification; Anatomical Therapeutic Chemical Classification; ATIIA; angiotensin II receptor antagonist; BSEP; bile s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Herbal Products and the Liver: A Review of Adverse Effects and Mechanisms

Keywords: دیلی; Dietary Supplement Health and Education Act; Contamination and Adulteration; Herbal Therapie; sSilymarin; ALT; alanine aminotransferase; CAM; complementary and alternative medicine; CHC; chronic hepatitis C; CYP; cytochrome P450; DILI; drug-induced liver

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Quinolones-induced hypersensitivity reactions

Keywords: دیلی; ADR; adverse drug reaction; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CI; confidence interval; DILI; drug-induced liver injury; FDE; fixed drug eruption; HSR; hypersensitivity syndrome reaction; γGT; gamma gluthamyl transferase; IDH

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

EASL Clinical Practice Guidelines: Autoimmune hepatitis

Keywords: دیلی; ACG; American College of Gastroenterology; AGA; American Gastroenterological Association; ANCA; Antineutrophil cytoplasmic antibodies; APECED; Autoimmune polyendocrinopathy-cadidiasis ectodermal dystrophy; AS; acute severe autoimmune; CNI; Calcineurin inh

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Protein tyrosine phosphatase 1B (PTP1B): A key regulator and therapeutic target in liver diseases

Keywords: دیلی; PTKs; protein tyrosine kinases; PTPs; protein tyrosine phosphatases; PTP1B; protein tyrosine phosphatase 1B; NAFLD; non-alcoholic fatty liver disease; HCC; hepatocellular carcinoma; DSPs; dual specificity phosphatases; LMW; low molecular weight; RPTPs; tr

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

Zebrafish: An Important Tool for Liver Disease Research

Keywords: دیلی; Development; Technology; Liver Cancer; Toxicology; Regeneration; ALD; alcoholic liver disease; CYP; cytochrome P450; DILI; drug-induced liver injury; DMBA; dimethylbenzanthracene; dpf; days postfertilization; ER; endoplasmic reticulum; FLD; fatty liver di

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2015 سفارش ترجمه

The role of intrahepatic CD3 +/CD4 −/CD8 − double negative T (DN T) cells in enhanced acetaminophen toxicity

Keywords: دیلی; GrB; granzyme B; DN T; double negative T; APAP; acetaminophen; DILI; drug-induced liver injury; NAPQI; n-acetyl-benzoquinone imine; NK; natural killer; CTL; cytotoxic T lymphocytes; FasL; Fas ligand; Gr; granzyme; i.p; intraperitoneally; ALT; alanine tran

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Involvement of miRNAs in the early phase of halothane-induced liver injury

Keywords: دیلی; ACTB; β-actin; ALT; alanine aminotransferase; APAP; acetaminophen; CXCL1; chemokine (C-X-C motif) ligand 1; CYP; cytochrome P450; DILI; drug-induced liver injury; GAPDH; glyceraldehyde-3-phoshate dehydrogenase; Ct; cycle threshold; HAL; halothane; IL; in

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Use of Hy's Law and a New Composite Algorithm to Predict Acute Liver Failure in Patients With Drug-Induced Liver Injury

Keywords: دیلی; Idiosyncratic Hepatotoxicity; Prognostic Risk Factor; Prediction; Progression; ALF; acute liver failure; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUROC; area under receiver operating characteristic curve;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Case ReportSevere immune-mediated drug-induced liver injury linked to ibandronate: A case report

Keywords: دیلی; AST; aspartate aminotransferase; ALT; alanine aminotransferase; CT; computed tomography; HIV; human immunodeficiency virus; N; normal; DILI; drug-induced liver injury; AIH; auto-immune hepatitis; ULN; upper limit of normal; RUCAM; Roussel Uclaf Causality

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticleCHOP is a critical regulator of acetaminophen-induced hepatotoxicity

Keywords: دیلی; DILI; drug induced liver injury; APAP; acetaminophen (N-acetyl-p-aminophenol); NAPQI; N-acetylbenzoquinoneimine; GSH; glutathione; ER; endoplasmic reticulum; UPR; unfolded protein response; ALI; acute liver injury; ROS; reactive oxygen species; ALT; alani

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Isoniazid-induced cell death is precipitated by underlying mitochondrial complex I dysfunction in mouse hepatocytes

Keywords: دیلی; ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; BNPP; Bis-p-nitrophenyl phosphate; DILI; Drug-induced liver injury; ETC; Electron transport chain; HzN; Hydrazine; INH; Isoniazid (isonicotinic acid hydrazide); LDH; Lactate dehydrogenase; OC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه