
Peptides that activate the 20S proteasome by gate opening increased oxidized protein removal and reduced protein aggregation
Keywords: ALS; amyotrophic lateral sclerosis; AMC; 7-amido-4-methylcoumarin; z-ARR-AMC; z-Ala-Arg-Arg-amido-4-methylcoumarin; ChT-L; chymotrypsin-like proteasomal activity; DMF; N,N-dimethyl formamide; DMSO; dimethyl sulfoxide; DNPH; 2,4-dinitrophenylhydrazine; DTT