Keywords: Sex differentiation; Feminization; dmrt1; cyp19a1; Japanese eel;
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Keywords: Retinoic acid; Ovary; DMRT1; Granulosa; Sertoli;
Keywords: agpat4; the gene encoding 1-Acylglycerol-3-Phosphate O-Acyltransferase 4; arα; the gene encoding androgen receptor α; arβ; the gene encoding androgen receptor β; bdfn; the gene encoding Brain-derived neurotrophic factor; bglap; the gene encoding bone
Keywords: Chlordecone; Chinese rare minnow (Gobiocypris rarus); Endocrine disruption; Adverse outcome pathway (AOP); AOP; Adverse Outcome Pathway; MIE; Molecular Initiating Event; KE; Key Event; AO; Adverse Outcome; T; Testosterone; E2; Estradiol; ER; Estrogen Rece
Identification and dimorphic expression of sex-related genes during gonadal differentiation in sterlet Acipenser ruthenus, a primitive fish species
Keywords: Acipenser ruthenus; Sex differentiation; cyp19a1; foxl2; dmrt1; Amh;
Identification and differential expression of microRNAs in testis and ovary of Amur sturgeon (Acipenser schrenckii)
Keywords: Dmrt1; doublesex and Mab-3 related transcription factor 1; Sox9; SRY-box containing gene 9; VASA; VASA-like protein; Foxl2; forkhead box L2; AR; androgen receptor; ER; estrogen receptor; Vtg; vitellogenin; Cyp19a; cytochrome P450, family 19, subfamily A;
Expression and cellular localization of double sex and mab-3 related transcription factor 1 in testes of postnatal Small-Tail Han sheep at different developmental stages
Keywords: Sheep (Ovis aries); Dmrt1; Expression; Cellular localization;
Genetic sex identification and the potential sex determination system in the yellow drum (Nibea albiflora)
Keywords: Yellow drum (Nibea albiflora); Sex-specific marker; Dmrt1; Sex determination system;
Hypothalamus and pituitary transcriptome profiling of male and female Hong Kong grouper (Epinephelus akaara)
Keywords: AES; amino-terminal enhancer of split; AR; androgen receptor; Cyp19a1; cytochrome P450 Family 19 Subfamily A Member 1; DEGs; differentially expressed genes; Dmrt1; doublesex and Mab-3 related transcription Factor 1; Dmrt1bY/Dmy; Dmrt1b on the Y chromosome
Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads
Keywords: Amh; Anti-Müllerian hormone; Bmp4; Bone morphogenetic protein 4; Dax1; Dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1; Dhh; Desert hedgehog; Dmrt1; Doublesex and mab-3 related transcription factor 1; DM-W; W-li
Male-specific Dmrt1 is a candidate sex determination gene in spotted scat (Scatophagus argus)
Keywords: Sex determination gene; Fish; Dmrt1; Marker; Spotted scat (Scatophagus argus); Dmrt1; Doublesex and Mab-3 Related Transcription Factor 1; SD; sex-determination; Dmy; DM-domain gene on the Y chromosome; marker-assisted selection; MAS; ORF; open reading fra
CRISPR/Cas9-mediated simultaneous knockout of Dmrt1 and Dmrt3 does not recapitulate the 46,XY gonadal dysgenesis observed in 9p24.3 deletion patients
Keywords: Dmrt1; Dmrt3; CRISPR/Cas9; Gonadal dysgenesis; Sexual development; Testis;
Comparative transcriptome analysis of ovary and testis reveals potential sex-related genes and pathways in spotted knifejaw Oplegnathus punctatus
Keywords: cDNA; complementary deoxyribonucleic acid; NR; non-redundant protein databases; KOG; eukaryotic orthologus groups; KEGG; kyoto encyclopedia of genes and genomes; GO; gene ontology; qRT-PCR; quantitative real-time polymerase chain reaction; foxl2; forkhead
Expression pattern of foxl2 and dmrt1 in gonad of Amur sturgeon Acipenser schrenckii in relation to sex differentiation
Keywords: Amur sturgeon; Molecular sex differentiation; Morphological sex differentiation; mRNA expression; foxl2; dmrt1;
Estrogen alters gonadal soma-derived factor (Gsdf)/Foxl2 expression levels in the testes associated with testis-ova differentiation in adult medaka, Oryzias latipes
Keywords: Gsdf; gonadal soma-derived factor; Dmy; DM domain gene on the Y chromosome; Dmrt1; doublesex/mab-3 related transcription factor-1; Amh; anti-müllerian hormone; qPCR; quantitative PCR; EB; estradiol benzoate; EDC; endocrine disrupting chemicals; PBS; phos
CRISPR/Cas9-induced disruption of wt1a and wt1b reveals their different roles in kidney and gonad development in Nile tilapia
Keywords: Amh; Anti-Müllerian hormone; Cyp19a1a; cytochrome P450, family 19, subfamily A, polypeptide 1a; Cyp11b2; cytochrome P450, family 11, subfamily B, polypeptide 2; dah; days after hatching; Dmrt1; double sex- and mab-3-related transcription factor-1; Gsdf;
Morphological changes and regulation of the genes dmrt1 and cyp11b during the sex differentiation of barramundi (Lates calcarifer Bloch)
Keywords: Testicular differentiation; dmrt1; cyp11b; Asian seabass; Primordial germ cells; Gonad histology; In situ hybridization; Sertoli cells;
Asthma and lower airway diseaseDoublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages
Keywords: Asthma; genetic association; DMRT1; interaction; rs3812523; sex; single nucleotide polymorphism; ALSPAC; Avon Longitudinal Study of Parents and Children; Ankara; Clinical study population recruited in Ankara, Turkey; AP-1; Activator protein 1; BAMSE; Chil
SOX9 regulates expression of the male fertility gene Ets variant factor 5 (ETV5) during mammalian sex development
Keywords: AGRF; Australian genomic research facility; Amh; anti Müllerian hormone; BAC; bacterial artificial chromosome; CCL9; chemokine (C-C motif) ligand 9; CSLM; confocal laser scanning microscopy; CYP17A1; cytochrome p450 family 17, subfamily A, protein 1; Cyp
Androgen induces gonadal soma-derived factor, Gsdf, in XX gonads correlated to sex-reversal but not Dmrt1 directly, in the teleost fish, northern medaka (Oryzias sakaizumii)
Keywords: Gsdf; XX sex-reversal; Androgen; Medaka; Inbred HNI-II strain; Oryzias sakaizumii; Gsdf; gonadal soma-derived factor; Dmy; DM domain gene on Y chromosome; Dmrt1; doublesex/mab-3 related transcription factor-1; dpf; days post fertilization; dph; days post
Long-term exposure to environmentally relevant concentrations of progesterone and norgestrel affects sex differentiation in zebrafish (Danio rerio)
Keywords: NGT; norgestrel; P4; progesterone; Amh; anti-Mullerian hormone; Dmrt1; doublesex and mab-3 related transcription factor 1; Figa; factor in the germline alpha; Sox9a; sry-related high mobility group box-9a; Sox9b; sry-related high mobility group box-9b; Pg
DMRT1 is required for Müllerian duct formation in the chicken embryo
Keywords: DMRT1; Müllerian ducts; Chicken; Female reproductive tract; Sex development;
Gonadal soma-derived factor (gsdf), a TGF-beta superfamily gene, induces testis differentiation in the teleost fish Oreochromis niloticus
Keywords: gsdf; Sex differentiation; Sex determination; dmrt1; Nile tilapiaTGF-beta, transforming growth factor-beta; gsdf, gonadal soma-derived factor; Dmrt1, doublesex/mab-3-related transcription factor-1; dph, days post-hatching; qRT-PCR, quantitative one-step R
Expression characterization of testicular DMRT1 in both Sertoli cells and spermatogenic cells of polyploid gibel carp
Keywords: Cag; Carassius auratus gibelio; cDNA; complementary DNA; DAPI; 4â²,6-diamidino-2-phenylindole; Dmrt1; dsx and mab-3 related transcription factor 1; FITC; fluorescein isothiocyanate; IPTG; isopropylthio-β-d-galactoside; kDa; kilo-dalton; PAGE; polyacryla
DMRT1 mutations are rarely associated with male infertility
Keywords: DMRT1; male infertility; point mutation;
Short-term treatment of adult male zebrafish (Danio Rerio) with 17α-ethinyl estradiol affects the transcription of genes involved in development and male sex differentiation
Keywords: AMH; Anti-Mullerian Hormone; AR; Androgen Receptor; Cyp19a; Cytochrome p-45019a; Dmrt1; double sex and mab-related protein; Dmy; master sex determination gene of the Y chromosome; EDC; endocrine disrupting chemical; ER-α; Estrogen Receptor alpha; ER-β;
Evolutionary history of two divergent Dmrt1 genes reveals two rounds of polyploidy origins in gibel carp
Keywords: Dmrt1; Sex determination; Polyploidy; Diploidization; Evolutionary history;
Expression profiling of the sex-related gene Dmrt1 in adults of the Lusitanian toadfish Halobatrachus didactylus (Bloch and Schneider, 1801)
Keywords: APA; alternative polyadenylation; bp; base pairs; cDNA; DNA complementary to RNA; DEPC; diethyl dicarbonate; IHC; immunohistochemistry; ISH; in situ hybridization; mRNA; messenger RNA; ORF; open reading frame; PBST; phosphate buffered saline with Tween 20
Differential role of the estrogen receptors ESR1 and ESR2 on the regulation of proteins involved with proliferation and differentiation of Sertoli cells from 15-day-old rats
Keywords: Estrogen receptors; Sertoli cells; CCND1; CDKN1B; GATA-1; DMRT1;
Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads
Keywords: PFA/PBS; paraformaldehyde in PBS; PCR; polymerase chain reaction; RCASBP/A; replication competent Avian Rous Sarcoma virus, Bryan titre polymerase, strain A; DMRT1; Drosophila Doublesex and C. elegans mab-3 related transcription factor, #1; SOX9; SRY-like
Testosterone implants modify the steroid hormone balance and the gonadal physiology of gilthead seabream (Sparus aurata L.) males
Keywords: ISM; in situ forming microparticle implant; T; testosterone; 11KT; 11-ketotestosterone; E2; 17β-estradiol; OHT; 11β-hydroxytestosterone; DHT; dihydrotestosterone; AR; androgen receptor; βdiol; 5α-androstane-3β17β-diol; RCs; reproductive cycles; AGs;
Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line
Keywords: Dmrt1; Nanos3; Teratoma; TGCT; Pluripotency; Germ cell;
Molecular identification and expression of FOXL2 and DMRT1 genes from willow minnow Gnathopogon caerulescens
Keywords: FOXL2; DMRT1; Temperature-dependent sex determination; Cyprinidae
Absence of inactivating mutations and deletions in the DMRT1 and FGF9 genes in a large cohort of 46,XY patients with gonadal dysgenesis
Keywords: 46,XY gonadal dysgenesis; DMRT1; FGF9; Testicular development; 3’ UTR microsatellite
Molecular mechanisms of temperature-dependent sex determination in the context of ecological developmental biology
Keywords: Temperature; Sex determination; Gonad; FoxL2; Dmrt1; Development;
DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary
Keywords: Dmrt1; DM domain; Meiosis; Stra8; Ovary
Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation
Keywords: GATA4; FOG2; Dmrt1; Testis; Sex determination;
Deleción 9p-. Disgenesia gonadal asociada a retraso mental e hipoplasia del cuerpo calloso. ¿Síndrome de genes contiguos?
Keywords: Disgenesia gonadal; Deleción 9p; Retraso mental; Cuerpo calloso; Diferenciación sexual; DMRT1; DMRT2Gonadal dysgenesis; 9p deletion; Mental retardation; Corpus callosum; Sexual differentiation; DMRT1 and DMRT2
Sexually dimorphic expression of dmrt1 in immature and mature Atlantic cod (Gadus morhua L.)
Keywords: Atlantic cod; Spermatogenesis; Sex dimorphism; DM domain; Dmrt1; Gadus morhua
Control of sex development
Keywords: sex development; sex determination; sex differentiation; ovary; testis; disorders of sex development (DSD); bipotential state; DSD; Disorders of sex development; Pax2; Paired Homeobox 2; Emx2; Empty spiracle homolog 2; Lhx9; Lim Homeobox protein 9; WT1; W
Quantitative mRNA expression of sox3 and DMRT1 during sex reversal, and expression profiles after GnRHa administration in black porgy, Acanthopagrus schlegeli
Keywords: Black porgy; DMRT1; sox3; Sex reverse; GnRHa
Identification and expression of a factor of the DM family in the oyster Crassostrea gigas
Keywords: Oyster; Crassostrea gigas; Dmrt1; Dmrt4; Dmrt5; Sex determination
Alternative transcripts of DMRT1 in the European sea bass: Expression during gonadal differentiation
Keywords: DMRT1; Sex differentiation; Dicentrarchus labrax; Alternative splicing; Gonadal development
Molecular cloning and quantitative expression of sexually dimorphic markers Dmrt1 and Foxl2 during female-to-male sex change in Epinephelus merra
Keywords: Honeycomb grouper; Protogynous sex change; Molecular cloning; Sexually dimorphic markers; Foxl2; Dmrt1
DMRT gene cluster analysis in the platypus: New insights into genomic organization and regulatory regions
Keywords: DMRT1; DMRT genes; Platypus; Gene annotation; Sex determination; CNGs
Generation of Antibodies Against DMRT1 and DMRT4 of Oreochromis aurea and Analysis of Their Expression Profile in Oreochromis aurea Tissues
Keywords: DMRT1; DMRT4; prokaryotic expression; polyclonal antibody; expression profile
Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation
Keywords: DMRT1; Conditional targeting; Testis; Sertoli; Gonocyte; Spermatogenesis; Autonomous
Differential and spermatogenic cell-specific expression of DMRT1 during sex reversal in protogynous hermaphroditic groupers
Keywords: DMRT1; Sox3; Sox9; Grouper; Gonad; Sex differentiation; Sex reversal; Spermatogenesis