دانلود مقالات ISI درباره Eurl Ecvam + ترجمه فارسی

الزامات قانونی بین المللی برای آزمایش حساسیت پوست

International regulatory requirements for skin sensitization testing

Keywords: Skin sensitization testing; Alternative approaches; Non-animal methods; Regulatory requirements; Defined approaches; ANVISA; Brazilian Health Regulatory Agency; CCPSA; Canada Consumer Product Safety Act; CLP; Classification, Labelling, and Packaging; CONC

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2018 سفارش ترجمه

تست های کمی ژنتیک سمیت برای تجزیه و تحلیل از گیاهان دارویی: یک بررسی سیستماتیک

Quantitative genotoxicity assays for analysis of medicinal plants: A systematic review

Keywords: A; Acetone extract; AAE; Water-acetone extract; AC; Alliun cepa; ACE; Acetate extract; AE; Aqueous extract; AEE; Hydroalcoholic extract; AI; Apoptosis-inducing; Ames; Bacterial reverse mutation assay; AN; Aspergillus nidulans; ANVISA; Agência Nacional

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

لیست های توصیه شده از مواد شیمیایی ژنوتوکسیک و غیر ژنوتیک را برای ارزیابی عملکرد جدید یا بهبود یافته آزمایشات ژنتیکی سمیت به روز رسانی کنید

Updated recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests

Keywords: CA; chromosomal aberrations; MLA; mouse lymphoma tk+/− mutation assay; MN; micronuclei; UDS; unscheduled DNA synthesis; IARC; International Agency for Research on Cancer; NTP; National Toxicology Program; RTG; relative total growth; E; equivocal; ip; in

دانلود رایگان متن کامل مقاله ISI 91 صفحه سال انتشار : 2016 سفارش ترجمه

SkinEthic™ HCE Eye Irritation Test: Similar performance demonstrated after long distance shipment and extended storage conditions

Keywords: BLR; Between Laboratory Reproducibility; CAS RN; Chemical Abstracts Service Registry Number; Cat 1; UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye; Cat 2; UN GHS classification for chemicals causing r

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2019 سفارش ترجمه

Usefulness of the EpiSkin™ reconstructed human epidermis model within Integrated Approaches on Testing and Assessment (IATA) for skin corrosion and irritation

Keywords: BU; Bottom-Up; CAS RN; Chemical Abstracts Service Registry Number; Cat; Category; EURL ECVAM; European Union Reference Laboratory for Alternatives to Animal Testing; ESAC; ECVAM Scientific Advisory Committee; EU; European Union; EU CLP; European Union Sys

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2019 سفارش ترجمه

CON4EI: SkinEthic™ Human Corneal Epithelium Eye Irritation Test (SkinEthic™ HCE EIT) for hazard identification and labelling of eye irritating chemicals

Keywords: BCOP; Bovine Corneal Opacity and Permeability; BCOP LLBO; Bovine Corneal Opacity and Permeability Laser Light based Opacitometer; CAS RN; Chemical Abstracts Service Registry Number; Cat1; UN GHS classification for chemicals causing irreversible effects on

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme

Keywords: ADME; absorption, distribution, metabolism, elimination; AOP; adverse outcome pathway; EFSA; European Food and Safety Agency; EURL ECVAM; European Union Reference Laboratory for Alternatives to Animal Testing; FDA; US Food and Drug Administration; IATA; I

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

A way forward of alternative methods in China: Implementation of skin corrosivity potential using in vitro reconstructed human epidermis

Keywords: CASRN; Chemical Abstract Service Registry Number; d-PBS; Dulbecco's Phosphate Buffered Saline; EURL ECVAM; European Union Reference Laboratory for European Centre for the Validation of Alternative Methods; GHS; Globally harmonized system of classification

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

CON4EI: EpiOcular™ Eye Irritation Test (EpiOcular™ EIT) for hazard identification and labelling of eye irritating chemicals

Keywords: DBALM; Database of Alternative Methods at the European Commission's Joint Research Centre; Cat 1; UN GHS/EU CLP classification for chemicals causing irreversible effects on the eye/serious damage to the eye; Cat 2; UN GHS/EU CLP classification for chemica

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

CON4EI: CONsortium for in vitro Eye Irritation testing strategy - EpiOcular™ time-to-toxicity (EpiOcular ET-50) protocols for hazard identification and labelling of eye irritating chemicals

Keywords: DBALM; Database of Alternative Methods at the European Commission's Joint Research Centre; Cat 1; UN GHS/EU CLP classification for chemicals causing irreversible effects on the eye/serious damage to the eye; Cat 2; UN GHS/EU CLP classification for chemica

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Finding synergies for 3Rs - Toxicokinetics and read-across: Report from an EPAA partners' Forum

Keywords: Physiologically-based kinetic (PBK) modelling; Hazard and risk assessment; Weight-of-evidence (WoE); Threshold of toxicological concern (TTC); In vitro to in vivo extrapolation (IVIVE); Integrated approach for testing and assessment (IATA); Absorption; Di

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

The challenge of the application of 'omics technologies in chemicals risk assessment: Background and outlook

Keywords: Omics; Transcriptomics; Weight-of-evidence; Registration, Evaluation, Authorisation, and Restriction (REACH); Plant protection products; Regulatory toxicology; Hazard assessment; Test method validation; Test method standardisation; AOP; Adverse outcome pa

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Lacking applicability of in vitro eye irritation methods to identify seriously eye irritating agrochemical formulations: Results of bovine cornea opacity and permeability assay, isolated chicken eye test and the EpiOcular™ ET-50 method to classify acco

Keywords: Serious eye damage; EpiOcular ET-50; Isolated chicken eye test; (Modified) bovine corneal opacity and permeability test; Agrochemical formulation; Classification; AAALAC; Association for Assessment and Accreditation of Laboratory Animal Care; BCOP; bovine

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

Keywords: Regulatory toxicology; Transcriptomics; Metabolomics; Good laboratory practice (GLP); Weight-of-evidence (WoE); Adverse outcome pathway (AOP); Mode-of-action (MoA); Gene expression; Differentially expressed genes; ANOVA; Analysis of variance; AOP; Adverse

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Predicting skin sensitisation using a decision tree integrated testing strategy with an in silico model and in chemico/in vitro assays

Keywords: Skin sensitisation; Derek Nexus; DPRA; KeratinoSens; LuSens; h-CLAT; U-SENS; Integrated testing strategy; In silico assessment; ACD; allergic contact dermatitis; AOP; adverse outcome pathway; CLP; classification labelling and packaging; DC; dendritic cell

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Assessment of cosmetic ingredients in the in vitro reconstructed human epidermis test method EpiSkin™ using HPLC/UPLC-spectrophotometry in the MTT-reduction assay

Keywords: CAS RN; Chemical Abstract Service Registry Number; R2; coefficient of determination; Cat. 1; Category 1; Cat. 2; Category 2; EIT; eye irritation test; DG SANCO; European Commission Directorate General for Health and Consumer Protection; EURL ECVAM; Europe

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals

Keywords: R2; Coefficient of Determination; CV; Coefficient of Variation; EIT; Eye Irritation Test; EIVS; Eye Irritation Validation Study; DG SANCO; European Commission Directorate General for Health and Consumer Protection; EURL ECVAM; European Union Reference Lab

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? II. Construction and analysis of a consolidated database

Keywords: EURL ECVAM; EU Reference Laboratory for Alternatives to Animal Testing; GLP; Good Laboratory Practices; IARC; International Agency for Research on Cancer; MLA/tk; mouse lymphoma Tk+/− gene mutation assay; Hprt; hypoxanthine-guanine phosphoribosyl transf

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه