Ascorbic acid rescues cardiomyocyte development in Fgfr1â/â murine embryonic stem cells
Keywords: FGFR1; Cardiomyocyte differentiation; Embryonic stem cell; Ascorbic acid;
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αvβ3 Integrin and Fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of Tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma
Keywords: Glioblastoma; Farnesyltransferase; FGFR1; ILK; Integrins; Radiotherapy; Phase II;
Increased levels of microRNA-424 are associated with the pathogenesis of fetal growth restriction
Keywords: Fetal growth restriction; Placenta; miRNA-424; MEK1; FGFR1
A ZMYM2-FGFR1 8p11 myeloproliferative neoplasm with a novel nonsense RUNX1 mutation and tumor lysis upon imatinib treatment
Keywords: ZMYM2; FGFR1; RUNX1; imatinib; tumor lysis
Fibroblast growth factor receptor 1 (FGFR1) copy number is an independent prognostic factor in non-small cell lung cancer
Keywords: FGFR1; Fibroblast growth factor receptor; Lung cancer; NSCLC; Squamous cell carcinoma; Amplification; Chromogenic silver in situ hybridisation
Prognostic Value of Fibroblast Growth Factor Receptor 1 Gene Locus Amplification in Resected Lung Squamous Cell Carcinoma
Keywords: FGFR1; Amplification; Squamous cell carcinoma; Lung; Prognosis; Metastasis
Akt and mTORC1 Have Different Roles During Liver Tumorigenesis in Mice
Keywords: Liver Cancer; Mouse Model; Signal Transduction; Gene Disruption; Akt; v-akt murine thymoma viral oncogene homolog 1; Alb; albumin; DKO; double knock-out; DMEM; Dulbecco's modified Eagle medium; EGF; epidermal growth factor; FBS; fetal bovine serum; FGFR1;
The Differential Diagnosis of Eosinophilia in Neoplastic Hematopathology
Keywords: Eosinophilia; PDGFRA; PDGFRB; FGFR1; Systemic mastocytosis; KIT; Chronic eosinophilic leukemia; Hypereosinophilic syndrome; Myeloproliferative neoplasms
A de novo interstitial deletion of 8p11.2 including ANK1 identified in a patient with spherocytosis, psychomotor developmental delay, and distinctive facial features
Keywords: FGFR1; fibroblast growth factor receptor 1 gene; ANK1; ankyrin 1 gene; OFC; occipitofrontal circumference; SD; standard deviation; MCV; mean corpuscular volume; MCH; mean corpuscular hemoglobin; MCHC; mean corpuscular hemoglobin concentration; LH; luteini
FGFR1 Amplification in Squamous Cell Carcinoma of The Lung
Keywords: Squamous cell lung cancer; FGFR1; Amplification
SÃndrome de Crouzon: a propósito de 2 casos. Entidades craneoestenóticas alélicas de los genes FGFR
Keywords: Acantosis nigricans; Antley-Bixler; Apert; Beare-Stevenson; Craneosinostosis; Crouzon; FGFR1; FGFR2; FGFR3; Jackson-Weiss; Muenke; Enanismo en sacabocados; Pfeiffer; Saethre-Chotzen; Acanthosis nigricans; Antley-Bixler; Apert; Beare-Stevenson; Craniosynos
Evidence that FGFR1 loss-of-function mutations may cause variable skeletal malformations in patients with Kallmann syndrome
Keywords: FGFR1; Kallmann syndrome; KAL2; skeletal malformations
Adipocyte-secreted factors increase osteoblast proliferation and the OPG/RANKL ratio to influence osteoclast formation
Keywords: ALP; Alkaline phosphatase; bFGF; Basic fibroblast growth factor; BMI; Body mass index; BMD; Bone mineral density; CM; Control medium; DKK; Dickkopf; EGF; Epidermal growth factor; FCCM; Fat-cell conditioned-medium; FGFR1; Fibroblast growth factor receptor
Partial reduction in neural cell adhesion molecule (NCAM) in heterozygous mice induces depression-related behaviour without cognitive impairment
Keywords: Neural cell adhesion molecule (NCAM); NCAM+/− mice; FGFR1; Depression; Learning
Agonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family
Keywords: Fibroblast growth factors; FGFR1; Homodimerization; BRET; MAPK;
Single-domain antibodies that compete with the natural ligand fibroblast growth factor block the internalization of the fibroblast growth factor receptor 1
Keywords: FGF; fibroblast growth factor; FGFR1; fibroblast growth factor receptor 1; VHH; heavy chain variable domain; Single-domain antibodies; Llama VHH; Fibroblast growth factor receptor 1; Competitive elution; Receptor internalization; MCF7 cells;
Genome-wide association study of blood pressure response to methylphenidate treatment of attention-deficit/hyperactivity disorder
Keywords: ADHD; attention-deficit/hyperactivity disorder; MTS; methylphenidate transdermal system; SNP; Single Nucleotide Polymorphism; FERM; Protein 4.1, Ezrin, Radixin, Moesin; bpm; beats per minute; bp; Base Paur; VNTR; Variable Number Tandem Repeat; DSM-IV-TR;
Role of fibroblast growth factor (FGF) signaling in the neuroendocrine control of human reproduction
Keywords: GnRH deficiency; Kallmann syndrome; FGF signaling; FGFR1; FGF8; Oligogenicity
The two faces of myeloproliferative neoplasms: Molecular events underlying lymphoid transformation
Keywords: Tyrosine kinase; FGFR1; JAK2; Lymphoblastic leukaemia; 8p11
Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo
Keywords: PTH; parathyroid hormone; DMP1-caPTHR1; dentin matrix protein 1-constitutively active PTH receptor 1 mice; FGF23; fibroblast growth factor 23; PTHrP; PTH related protein; FGFR1; FGF receptor 1; GALNT3; galactosaminyl transferase 3; BMP; bone morphogenetic
FGF signaling regulates rod photoreceptor cell maintenance and regeneration in zebrafish
Keywords: retina; zebrafish; Fgf; Fgfr1; regeneration; hsp70:dn-fgfr1; homeostasis; rod precursor
Idiopathic hypogonadotropic hypogonadism in a mother and her monozygotic twins born after a single embryo transfer
Keywords: FGFR1; hypogonadotropic hypogonadism; microphallus; monozygotic twins;
Research ReportFGF-2/FGFR1 neurotrophic system expression level and its basal activation do not account for the age-dependent decline of precursor cell proliferation in the subventricular zone of rat brain
Keywords: SVZ; subventricular zone; BrdU; bromodeoxyuridine; FGF-2; fibroblast growth factor-2; FGF-2; FGFR1; Neurogenesis; Subventricular zone; Neuronal precursor cells; Aging;
Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients
Keywords: chronic kidney disease; FGF23; FGFR1; Klotho; parathyroid; secondary hyperparathyroidism
Construction of recombinant FGFR1 containing full-length gene and its potential application
Keywords: Construction; FGFR1; Overexpression; Application
Parathyroid Klotho and FGF-receptor 1 expression decline with renal function in hyperparathyroid patients with chronic kidney disease and kidney transplant recipients
Keywords: chronic kidney disease; FGF23; FGFR1; Klotho; secondary hyperparathyroidism; vitamin D3
Clinical genetics of Kallmann syndrome
Keywords: Syndrome de Kallmann-de Morsier; Syndrome CHARGE; Hypogonadisme hypogonadotrope; Anosmie; KAL1; FGFR1; FGF8; PROKR2; PROK2; CHD7Kallmann syndrome; CHARGE syndrome; Hypogonadotropic hypogonadism; Anosmia; KAL1; FGFR1; FGF8; PROKR2; PROK2; CHD7
AP-2α suppresses skeletal myoblast proliferation and represses fibroblast growth factor receptor 1 promoter activity
Keywords: Myoblast; Proliferation; FGFR1; Promoter; Transcription; Myogenesis;
Dynamic roles of FGF-2 and Anosmin-1 in the migration of neuronal precursors from the subventricular zone during pre- and postnatal development
Keywords: Olfactory system; Neuronal migration; Rostral migratory stream; Proliferation; Neural stem Cell; FGFR1; Chemotropic molecules
Fibroblast growth factor receptor 1 regulates the differentiation and activation of osteoclasts through Erk1/2 pathway
Keywords: FGFR1; Bone remodeling; Osteoclast; MAPK
FGFR1 forms an FRS2-dependent complex with mTOR to regulate smooth muscle marker gene expression
Keywords: FGFR1; FRS2; mTOR; Rapamycin; SM α-actin; VSMC;
Hypogonadisme hypogonadotrope congénital
Keywords: Hypogonadotropic hypogonadism; GNRHR; GPR54; KAL1; FGFR1; ProKR2; Prok2Hypogonadisme hypogonadotrope; GNRHR; GPR54; KAL1; FGFR1; ProKR2; Prok2
Anosmin-1 stimulates outgrowth and branching of developing Purkinje axons
Keywords: axon guidance; neuritic sprouting; regeneration; cerebellum; fibroblast growth factor receptor; FGFR; ANOVA; analysis of variance; APC; adenomatous polyposis coli tumor suppressor gene; CHO; Chinese hamster ovary; DAPI; 4,6-diamidino-2-phenylindole; E; em
The fibroblast growth factor system is downregulated following social defeat
Keywords: Social defeat; FGF2; FGFR1; In situ hybridization; Depression;
Common features of myeloproliferative disorders with t(8;9)(p12;q33) and CEP110–FGFR1 fusion: Report of a new case and review of the literature
Keywords: t(8 ;9); CEP110; FGFR1; Myeloproliferative disorder; 8p12; 9q33
Gene expression profiling of major depression and suicide in the prefrontal cortex of postmortem brains
Keywords: Microarray; Major depression; Suicide; Postmortem brain; FGFR1; NCAM1; CAD; ATP1A3
Fibroblast growth factor receptor 1 gene expression is required for cardiomyocyte proliferation and is repressed by Sp3
Keywords: Cardiomyocyte; Proliferation; Transcription; FGFR1; Promoter; Sp3
Promotion of neurite outgrowth by fibroblast growth factor receptor 1 overexpression and lysosomal inhibition of receptor degradation in pheochromocytoma cells and adult sensory neurons
Keywords: FGFR1; MAP kinase; leupeptin; lysosome; sensory neurons; axonal growthDRG, dorsal root ganglia; ERK, extracellular signal-regulated kinase; FGF, fibroblast growth factor; FGFR, fibroblast growth factor receptor; FGFR1L, fibroblast growth factor receptor 1
Nicotine-induced fibroblast growth factor-2 restores the age-related decline of precursor cell proliferation in the subventricular zone of rat brain
Keywords: Precursor proliferation; FGF-2; FGFR1; SVZ; Nicotine; Aged
Clonal evolution of 8p11 stem cell syndrome in a 14-year-old Chinese boy: A review of literature of t(8;13) associated myeloproliferative diseases
Keywords: 8p11 stem cell syndrome; FGFR1; Myeloproliferative disease; Precursor T-cell lymphoblastic lymphoma
Novel inhibitor for fibroblast growth factor receptor tyrosine kinase
Keywords: FGFR1; FGFR1 inhibitor; SU6668; Phenyl indolin-2-one; Docking; Binding mode; Antiproliferation; Antiangiogenesis
Fibroblast Growth Factor Receptor-1 is Required for Long-Term Potentiation, Memory Consolidation, and Neurogenesis
Keywords: Dentate gyrus; FGFR1; gene knockout; memory consolidation; neurogenesis; proliferation; synaptic plasticity
Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand–receptor relationships
Keywords: Medaka; Zebrafish; fgfr1; Mesoderm; fgf8; Evolution; Divergence of gene function
The distribution of the growth factors FGF-2 and VEGF, and their receptors, in growing red deer antler
Keywords: FGF-2; FGFR1; FGFR2; FGFR3; VEGF; VEGFR-2; Antler; Integument; Epidermis; Mesenchyme; Chondrocyte; Osteoblast; Immunohistochemistry
Cyclic AMP regulates the expression and nuclear translocation of RFC40 in MCF7 cells
Keywords: cAMP; cyclic adenosine 3â²,5â²-cyclic monophosphate; APC; anaphase-promoting complex; BrdU; bromodeoxyuridine; CDKs; cyclin-dependent kinases; CKIs; cyclin-dependent kinase inhibitors; CREB; cAMP-responsive element binding proteins, C-subunit/Catα, cat
Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum
Keywords: Anterior commissure; Corpus callosum; Hippocampal commissure; FGF; Fgfr1; Patterning; Telencephalon; Midline; Glia; Septum
FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region
Keywords: FGFR1; Isthmic organizer; Midbrain; Hindbrain; Neuronal progenitors; Proliferation; Midbrain dopaminergic neurons; Raphe nuclei; Locus coeruleus; Microarray;
Eosinophilic disorders: Molecular pathogenesis, new classification, and modern therapy
Keywords: hypereosinophilic syndrome; chronic eosinophilic leukemia; FIP1L1-PDGFRA; PDGFRB; FGFR1
Expression of Fgf and Tgfβ signaling related genes during embryonic endochondral ossification
Keywords: Endochondral ossification; Chondrocyte differentiation; Ihh; Pthr; Bmp2; Bmp3; Bmp4; Bmp6; Bmp7; Noggin; Follistatin; Inhβa; Activin; Tgfβ1; Tgfβ2; Tgfβ3; Bmpr1a; Bmpr1b; Bmpr2; Acvrl1; Acvr1; Acvr1b; Acvr2; Tgfβr1; Smad1; Smad3; Smad5; Fgf2; Fgf8; F
Blood Eosinophilia: A New Paradigm in Disease Classification, Diagnosis, and Treatment
Keywords: AEC; absolute eosinophil count; CEL; chronic eosinophilic leukemia; CML; chronic myeloid leukemia; CMML; chronic myelomonocytic leukemia; FGFR1; fibroblast growth factor receptor 1; FISH; fluorescence in situ hybridization; HES; hypereosinophilic syndrome