Keywords: جعبه O جعبه O; As(III); arsenite; As(V); arsenate; MMA; monomethylarsonic acid; Nox 2; NADPH oxidase; NOS; nitric oxide synthases; ETC; electron transport chain; WAT; white adipose tissue; BAT; brown adipose Tissue; UCP; uncoupling protein; α-KDGH; α-ketoglutarate deh
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Keywords: جعبه O جعبه O; Hematophagy; Lipid metabolism; Lipid transport; Vector insects; 20HE; 20-hydroxyecdysone; ACBP; acyl-CoA-binding protein; ACC; acetyl-CoA carboxylase; ACS; acyl-CoA synthetase; ACSF5; ACS family 5; ACSL; long-chain ACS; ACSVL; very long-chain ACS; AGPAT;
Keywords: جعبه O جعبه O; COL; collagen; FoXO; forkhead box O; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HGF; hepatocyte growth factor; HSP; heat shock protein; IL; interleukin; LAM; laminin; MCP; monocyte chemoattractant protein; MuRF1; muscle RING-finger protein-1; NCIT;
Keywords: جعبه O جعبه O; AAA; ATPases associated with diverse cellular activities; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; ABC; ATP-binding cassette; ABCE1; ATP binding cassette subfamily E member 1; AD; Alzheimer's disease; AIF; apoptosis inducing factor; Akt; Alpha se
Keywords: جعبه O جعبه O; Glycerol; BALB/cHeA; Gluconeogenesis; Glycogenic amino acid; ALT; alanine amino transferase; ATGL; adipocyte triglyceride lipase; BCAA; branched chain amino acids; DHAP; dihydroxyacetone phosphate; FoxO; forkhead box O; GPD; glycerol-3-phosphate dehydroge
Keywords: جعبه O جعبه O; Feedback regulation; Systems stability; Mathematical modelling; Network analysis; Drug resistance, Signal transduction, Network dynamics; MST2; Mammalian STE20-like protein kinase 2; Raf-1; v-raf-1 murine leukemia viral oncogene homolog 1; MEK; Mitogen-Ac
Keywords: جعبه O جعبه O; Cyr61; cysteine-rich protein 61; RA; rheumatoid arthritis; IL-17; interleukin-17; ECM; extracellular matrix; CTGF; connective tissue growth factor; IGFBP; insulin-like growth factor binding protein domain; VWC; von Willebrand type C repeat; TSP-1; thrombo
Keywords: جعبه O جعبه O; GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;
Keywords: جعبه O جعبه O; AD; Alzheimer's disease; T2DM; type II diabetes mellitus; Aβ; amyloid beta; NFT; neurofibrillary tangles; IR; insulin resistance; InsR; insulin receptors; IRS; InsR substrate; IGF; insulin growth factor; ICV; intracerebroventricular; STZ; streptozotocin;
Keywords: جعبه O جعبه O; Glucocorticoids; Bone; Muscle; Oxidative stress; Forkhead box O
Keywords: جعبه O جعبه O; Akt; serine-threonine kinase; DAG; directed acyclic graph; DnC; sampling time at day  n of a Control explant; DnS; sampling time at day  n of a Stimulated explant; ELF; extremely low frequency; EMF; electromagnetic field; ERKs; extracellular signal-
Keywords: جعبه O جعبه O; Cox; cyclooxygenase; CREB; cAMP response element binding protein; CACS; cancer-related anorexia and cachexia syndrome; CRP; C-reactive protein; COPD; chronic obstructive pulmonary disease; DAG; des-acyl ghrelin; ERK; extracellular signal-regulated kinase;
Keywords: جعبه O جعبه O; 4E-BP1; Eukaryotic translation initiation factor 4E binding protein; ACE; Angiotensin-converting enzyme; ANP; Atrial natriuretic peptide; BMD; Bone mineral density; BMI; Body mass index; BNP; Brain natriuretic peptide; CC; Cardiac cachexia; CHF; Chronic h
Keywords: جعبه O جعبه O; TGF-β; transforming growth factor-β; MSTN; myostatin gene; LAP; latency-associated peptide; FLRG; follistatin-related gene peptide; FSTL-3; follistatin like 3; GASP; growth/differentiation factor-associated serum protein; LTBP; latent TGF-β-binding pro
Keywords: جعبه O جعبه O; FOXO; forkhead box O; GC; glucocorticoids; MuRF-1; muscle RING-finger protein-1; mTOR; mammalian target of rapamycin; IGF-I; Insulin-like Growth Factor-I; eIF4E; eukaryotic translation initiation factor 4E; S6K1; ribosomal protein kinase 1; 4E-BP1; eukary
Keywords: جعبه O جعبه O; 4E-BP1; 4E-binding protein-1; AA; amino acid; ALS; autophagy-lysosomal system; AMPK; adenosine monophosphate-activated protein kinase; COPD; chronic obstructive pulmonary disease; CRP; C-reactive protein; ERK; extracellular signal regulated kinase; FFM; f
The β2-adrenergic receptor is involved in differences in the protein degradation level of the pectoral muscle between fast- and slow-growing chicks during the neonatal period
Keywords: جعبه O جعبه O; Ub; Ubiquitin; AR; adrenergic receptor; atrogin-1/MAFbx; muscle atrophy F-box; Foxo; forkhead box O; MeHis; 3-methylhistidine; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IGF-I; insulin-like growth factor-I; Chicken; β2-Adrenergic receptor; Protein
Role of Forkhead Box O (FOXO) transcription factor in aging and diseases
Keywords: جعبه O جعبه O; FOXO; Forkhead box O; DBD; DNA-binding domain; NLS; Nuclear localization sequence; NES; Nuclear export sequence; IRE; Insulin-responsive element; ARDs; Age-related diseases; RTK; Receptor tyrosine kinase; PI3K; Phosphoinositide 3kinase; SGK; Serum and glu
Forkhead box O proteins: Crucial regulators of cancer EMT
Keywords: جعبه O جعبه O; Forkhead box O; Cancer; Epithelial-mesenchymal transition;
Re-evaluating the role of FOXOs in cancer
Keywords: جعبه O جعبه O; RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen
KRAS-Mutant non-small cell lung cancer: From biology to therapy
Keywords: جعبه O جعبه O; BATTLE; Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination; BET; bromodomains and extra-terminal domain; CDK; cyclin-dependent kinase; Chk1; checkpoint kinase 1; CI; confidence interval; CUSTOM; Molecular Profiling and Targete
Association of Native American ancestry and common variants in ACE, ADIPOR2, MTNR1B, GCK, TCF7L2 and FTO genes with glycemic traits in Colombian population
Keywords: جعبه O جعبه O; ACE; angiotensin converting enzyme; MTNR1B; melatonin receptor 1B; GCK; glucokinase; TCF7L2; transcription factor 7 Like 2; FTO; alpha-ketoglutarate dependent dioxygenase; OR; odds ratio; IR; insulin resistance; T2D; type 2 diabetes; MS; metabolic syndrom
Mechanisms controlling the anti-neoplastic functions of FoxO proteins
Keywords: جعبه O جعبه O; ATM; ataxia telangiectasia mutated; cHL; classical hodgkin lymphoma; CML; chronic myelogenous leukemia; CSC; cancer stem cell; ERK; the extracellular signal-regulated kinase; ERα; the nuclear receptor estrogen receptor α; FoxO; forkhead box O; G6PC; glu
MEF2A regulates Calpain 3 expression in L6 myoblasts
Keywords: جعبه O جعبه O; MEF2; myogenic enhancer factor 2; Calpain; calcium-dependent, non-lysosomal cysteine protease; CAPN3; Calpain 3, calcium-dependent, non-lysosomal cysteine protease3; FoxO; Forkhead box O; HEK293; human embryonic kidney cells 293; EMSA; electrophoretic mob
Focusing on claudin-5: A promising candidate in the regulation of BBB to treat ischemic stroke
Keywords: جعبه O جعبه O; 5α-DHP; 5α-dihydroprogestrone; ABC; ATP-binding cassette; AF6; ALL-1-fused gene from chromosome 6; ALL; acute lymphoblastic leukemia; AMPAR; amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor; Ang-1; angiopoietin-1; AP-1; activator protein-1; BBB;
A splice junction-targeted CRISPR approach (spJCRISPR) reveals human FOXO3B to be a protein-coding gene
Keywords: جعبه O جعبه O; aa; amino acid(s); bp; base pairs; Cas9; CRISPR associated protein 9; cDNA; DNA complementary to RNA; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; DMSO; dimethylsulfoxide; Dox; doxycycline; dsDNA; double stranded DNA; FOXO; forkhead
FoxO4 activity is regulated by phosphorylation and the cellular environment during dehydration in the African clawed frog, Xenopus laevis
Keywords: جعبه O جعبه O; DPI-ELISA; Dehydration; Xenopus laevis; Western blotting; Forkhead box O; Myogenin;
Ribosomal protein L10A and signaling pathway
Keywords: جعبه O جعبه O; mRNA; messenger RNA; RpL10A; Ribosomal protein L10A; InR; insulin receptor; PCR; polymerase chain reaction; Akt; serine/threonine kinase; FOXO; forkhead box O; pre-mRNA; precursor mRNA; RSV; respiratory syncytial virus; Pwop phenotype; peas without pods p
FOXOs in cancer immunity: Knowns and unknowns
Keywords: جعبه O جعبه O; 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot
Overexpression of Sirt1 in mesenchymal stem cells protects against bone loss in mice by FOXO3a deacetylation and oxidative stress inhibition
Keywords: جعبه O جعبه O; ALP; alkaline phosphatase; Bmi-1; B cell-specific Moloney murine leukemia virus integration site 1; Bmi-1â/â; Bmi1 deficiency; Bmi-1+/â; Bmi-1 heterozygous; Col-I; type I collagen; Col-II; type II collagen; FOXO; Forkhead box O; GPX1; Glutathione pe
PI3K pathway in prostate cancer: All resistant roads lead to PI3K
Keywords: جعبه O جعبه O; CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P
Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity
Keywords: جعبه O جعبه O; Vascular smooth muscle; Vasoproliferative disease; Vascular smooth muscle cell; Phenotype switching; Signalling pathways; AJ; adherens junction; ApoE; apolipoprotein E; BMP; bone morphogenetic protein; CAD; coronary artery diseases; CADASIL; cerebral auto
Novel combined Ato-C treatment synergistically suppresses proliferation of Bcr-Abl-positive leukemic cells in vitro and in vivo
Keywords: جعبه O جعبه O; Arsenic trioxide; Cisplatin; Combination therapy; Bcr-Abl-positive leukemia; Apoptosis; APL; acute promyelocytic leukemia; ATO; arsenic trioxide; Ato-C; ATO/CDDP; CDDP; Cisplatin; CI; combination index; DRI; dose-reduction index; CML; Chronic myelogenous
Reduction in ins-7 gene expression in non-neuronal cells of high glucose exposed Caenorhabditis elegans protects from reactive metabolites, preserves neuronal structure and head motility, and prolongs lifespan
Keywords: جعبه O جعبه O; AGE; advanced glycation end-product; AU; arbitrary units; C. elegans; Caenorhabditis elegans; ctrl; control; DAF; abnormal dauer formation; DN; diabetic neuropathy; E. coli; Escherichia coli; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; FOX
Functional integration of complex miRNA networks in central and peripheral lesion and axonal regeneration
Keywords: جعبه O جعبه O; AAV(s); adeno-associated virus(es); ADAM; a disintegrin and metalloprotease; AGO(2); argonaut (2); AKT; protein kinase B; APC; adenomatous polyposis coli; ASO(s); antisense oligonucleotide(s); ATF3; activating transcription factor 3; BBB; blood brain barr
FOXOs in the impaired heart: New therapeutic targets for cardiac diseases
Keywords: جعبه O جعبه O; Forkhead box O; Ischemic cardiac diseases; Diabetic cardiomyopathy; Myocardial hypertrophy; Cardiac regeneration;
Forkhead box O transcription factors in chondrocytes regulate endochondral bone formation
Keywords: جعبه O جعبه O; Chondrocyte; Forkhead Box O; Hypertrophic; Growth plate; Redox homeostasis;
PGC-1α overexpression via local transfection attenuates mitophagy pathway in muscle disuse atrophy
Keywords: جعبه O جعبه O; PGC-1α; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; FoxO; forkhead box O; 4-HNE; 4-hydroxynonenal; Mul1; mitochondrial E3 ubiquitin protein ligase 1; PINK1; PTEN-induced putative kinase 1; Mfn2; mitofusin 2; mROS; mitochondrial
Molecular characterization and functional analysis of BdFoxO gene in the oriental fruit fly, Bactrocera dorsalis (Diptera: Tephritidae)
Keywords: جعبه O جعبه O; TOR; target of rapamycin; JNK; Jun NH2-terminal kinase; FoxO; forkhead box O; InR; insulin receptor; Akt; protein kinase B; PI3K; phosphatidylinositol 3-kinase; 4EBP; 4E binding protein; ILPs; insulin-like peptides; RT-qPCR; reverse transcription-quantita
The role of CD36 in the regulation of myocardial lipid metabolism
Keywords: جعبه O جعبه O; ACSL; acyl-coenzyme A synthetase; AMP; adenosine monophosphate; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ATGL; adipose triglyceride lipase; CPT; carnitine palmitoyltransferase; CVD; cardiovascular disease; FAT (CD36); fatty acid tr
A novel apoptosis-inducing mechanism of 5-aza-2â²-deoxycitidine in melanoma cells: Demethylation of TNF-α and activation of FOXO1
Keywords: جعبه O جعبه O; αTNF-α; mAb against human TNF-alpha; Bi-seq; bisulfite sequencing; ChIP; chromatin immunoprecipitation; FasL; Fas ligand; FOXO; Forkhead box O; mAb; monoclonal antibody; MSP; methylation-specific PCR; TNF-α; tumor necrosis factor-α; TRAIL; TNF-related
Natural lignans from Arctium lappa as antiaging agents in Caenorhabditis elegans
Keywords: جعبه O جعبه O; DCF; 2â²,7â²-dichlorofluorescein; DMSO; dimethyl sulfoxide; DPPH; 2,2-diphenyl-1-picrylhydrazyl; EGCG; epigallocatechin gallate; FOXO; Forkhead box O; GFP; green fluorescent protein; H2DCF; 2,7-dichlorodihydrofluorescein; HPLC; high performance liquid c
Antagonistic role of natural compounds in mTOR-mediated metabolic reprogramming
Keywords: جعبه O جعبه O; AMPK; AMP-activated protein kinase; EGCG; epigallocatechin-3-gallate; CG; cardiac glycoside; 4E-BP; eukaryotic initiation factor 4E (eIF4E)-binding protein; FAS; fatty acid synthase; FoxO; forkhead box O; GLUT; glucose transporter; HK2; hexokinase-2; HIF-
Redox-regulated fate of neural stem progenitor cells
Keywords: جعبه O جعبه O; ARE; antioxidant response element; bHLH; basic helix-loop-helix; BMI1; B lymphoma Mo-MLV insertion region 1 homolog; CtBPs; C-terminal binding proteins; DLL4; delta-like protein 4; DVL; disheveled; DOUX; dual oxidases; ES; embryonic stem cells; EGFR; epid
High sucrose consumption promotes obesity whereas its low consumption induces oxidative stress in Drosophila melanogaster
Keywords: جعبه O جعبه O; DILPs; Drosophila insulin-like peptides; FOXO; Forkhead box O; G6PDH; glucose-6-phosphate dehydrogenase; GR; glutathione reductase; GST; glutathione-S-transferase; 20-HE; 20-hydroxyecdysone; IDH; isocitrate dehydrogenase; IS; insulin signaling; JH; juveni
Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition
Keywords: جعبه O جعبه O; Methylseleninic acid (PubChem CID: 161597); Sodium selenite (PubChem CID: 24934); Cisplatin (PubChem CID: 441203); LY294002 (PubChem CID: 3973); MSA; methylseleninic acid; Se; selenium; PPP; pentose phosphate pathway; TCA; tricarboxylic acid; ROS; reactiv
MYC and metabolism on the path to cancer
Keywords: جعبه O جعبه O; 2-DG; 2-deoxyglucose; 4E-BP; eIF4E-binding protein; 5,10-methylene THF; 5,10-methylenetetrahydrofolate; ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ChIP-seq; chromatin immunoprecip
Redox modulation of adipocyte differentiation: hypothesis of “Redox Chain” and novel insights into intervention of adipogenesis and obesity
Keywords: جعبه O جعبه O; 6PGD; 6-phosphogluconate dehydrogenase; 20-HETE; 20-hydroxyeicosatetraenoic acid; AA; arachidonic acid; ADP; adenosine diphosphate; ADSCs; adipose-derived stem cells; aP2; fatty-acid binding protein; AREs; antioxidant response elements; ATP; adenosine tri
The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
Keywords: جعبه O جعبه O; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; ATP; adenosine triphosphate; Aβ; amyloid β peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; AMP; adenos
Wnt/β-catenin signaling regulates follicular development by modulating the expression of Foxo3a signaling components
Keywords: جعبه O جعبه O; APC; adenomatosis polyposis coli; CTNNB1; β-catenin; DMSO; dimethylsulfoxide; CYP11A1; P450 cholesterol side chain cleavage; CYP19A1; cytochrome P450 aromatase; FBS; fetal bovine serum; Foxo; Forkhead box O; FZD; frizzled; GSK3β; glycogen synthase kinas