
Rapamycin preserves the follicle pool reserve and prolongs the ovarian lifespan of female rats via modulating mTOR activation and sirtuin expression
Keywords: P70S6K; ribosomal protein S6 kinase; mTOR; the mammalian target of rapamycin; SIRT; silent information regulator; Tsc; tuberous sclerosis complex; mTORC1; the mammalian target of rapamycin complex 1; POF; premature ovarian failure; PTEN; phosphatase and t