دانلود مقالات ISI درباره Gef + ترجمه فارسی

miR-51 regulates GABAergic synapses by targeting Rab GEF GLO-4 and lysosomal trafficking-related GLO/AP-3 pathway in Caenorhabditis elegans

Keywords: GABA; γ-aminobutyric acid; PTZ; pentylenetetrazole; SNB-1; Synaptobrevin 1; GEF; guaninenucleotide exchange factor; SVs; synaptic vesicles; ACh; acetylcholine; NMJs; neuromuscular junctions; miRNAs; microRNAs; GluR; glutamate receptor; nAChR; neuronal ac

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets

Keywords: Platelet inhibition; Phosphoproteome; cGMP-dependent protein kinase/PKG; Small GTP-binding proteins; G proteins; NO; nitric oxide; PKA; protein kinase A; PKG; protein kinase G; PDE; phosphodiesterase; sGC; soluble guanylate cyclase; GPCR; G-protein couple

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

AtBET5 is essential for exine pattern formation and apical meristem organization in Arabidopsis

Keywords: ARF; auxin response factor; GEF; guanine nucleotide-exchange factors; GFP; green florescent protein; PI; propidium iodide; QC; quiescent center; RAM; root apical meristem; RNAi; RNA interference; RT-PCR; reverse transcription-polymerase chain reaction; SA

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

FLCN: The causative gene for Birt-Hogg-Dubé syndrome

Keywords: AEC; alveolar epithelial type II cell; AKT; protein kinase B; AMPK/Ampk; 5′-AMP activated protein kinase; AMPKα (also AAK-2); AMPKα subunit; ATP; adenosine triphosphate; Bcl-2; B-cell lymphoma 2; BHD; Birt-Hogg-Dubé; BAT; brown adipose tissue; C. ele

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

EMT: Mechanisms and therapeutic implications

Keywords: AJ; adherens junction; aPKC; atypical protein kinase; BM; basement membrane; βHLH; Beta helix-loop-helix; CSC; cancer stem cells; ECM; extracellular matrix; EMT; epithelial mesenchymal transition; FOX; Forkhead box; GAP; GTPase-activating proteins; GDI;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

EphBs and ephrin-Bs: Trans-synaptic organizers of synapse development and function

Keywords: βGal; β-Galactosidase; Aβ; amyloid-β; Abl; Abelson murine leukemia viral oncogene homolog; AD; Alzheimer's disease; AMPAR; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; APP; amyloid precursor protein; BLA; basolateral amygdala; CaMKI

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Up-regulation of NSP3 by Oligomeric Aβ Accelerates Neuronal Death Through Cas-independent Rap1A Activation

Keywords: aa; amino acid; Aβ; β-amyloid; AD; Alzheimer's disease; APP; amyloid precursor protein; CBD; Cas-binding domain; DIV; days in vitro; GEF; guanine nucleotide exchange factor; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; NBD; NSP3-binding domain; NSP3; nove

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Paving the Rho in cancer metastasis: Rho GTPases and beyond

Keywords: ADP; adenosine diphosphate; AMP; adenosine monophosphate; AMT; amoeboid-mesenchymal transition; APC; adenomatosis polyposis coli; Arp2/3; actin related protein 2/3; Cdc42; cell division control protein 42 homolog; CK1; casein kinase 1; COX-2; cyclooxygena

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension

Keywords: ADRF; adipocyte-derived relaxing factor; AE; anion exchanger; ATP; adenosine triphosphate; BH4; tetrahydrobiopterin; BKCa; big conductance Ca2+-sensitive K+ channel; CaM; calmodulin; cAMP; cyclic adenosine monophosphate; CAT; cysteine aminotransferase; CB

دانلود رایگان متن کامل مقاله ISI 88 صفحه سال انتشار : 2018 سفارش ترجمه

Heterogeneous electro-Fenton and photoelectro-Fenton processes: A critical review of fundamental principles and application for water/wastewater treatment

Keywords: 2,4-DCP; 2,4-dichlorophenol; 3D; three dimension; AB; alginate beads; AC; activated carbon; ACF; activated carbon felt; ACS; activated charcoal; AOPs; advanced oxidation processes; APHs; 4-Amino-3-hydroxy-2-p-tolylazonaphthalene- 1-sulfonic acid; APN; all

دانلود رایگان متن کامل مقاله ISI 115 صفحه سال انتشار : 2018 سفارش ترجمه

The small GTPase, Rab27, and its effectors and regulators participate in granule exocytosis by parotid acinar cells

Keywords: Slp; synaptotagmin-like protein; Slac2; Slp homolog lacking C2 domains; SHD; synaptotagmin-like protein homology domain; GST; glutathione S-transferase; IPR; isoproterenol; SLO; streptolysin O; GAP; GTPase activating protein; GEF; guanine nucleotide excha

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Indoleamine 2,3-dioxygenase regulates T cell activity through Vav1/Rac pathway

Keywords: HEK293; Human Embryonic Kidney 293 cells; FBS; Fetal bovine serum; IDO; Indoleamine 2,3-dioxygenase; IL; interleukin; PBMCs; Peripheral blood monouclear cells; TIL-Ts; T cells of tumor infiltrating lymphocytes; TCR; T cell receptor; Indoleamine 2,3-dioxyg

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewEmerging role of Cdc42-specific guanine nucleotide exchange factors as regulators of membrane trafficking in health and disease

Keywords: CDC42; GEF; Golgi; Membrane trafficking; Genetic diseases;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Machineries regulating the activity of the small GTPase Arf6 in cancer cells are potential targets for developing innovative anti-cancer drugs

Keywords: Arf6; GEF; GAP; Invasion; Metastasis; Tumor angiogenesis; Tumor growth; Anti-cancer drugs;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of Aplysia ARF6 induces neurite outgrowth and is sequestered by the overexpression of the PH domain of Aplysia Sec7 proteins

Keywords: 5-HT; 5-hydroxyltryptamine; PH; pleckstrin homology; ARF; ADP-ribosylation factor; GTPase; guanosine triphosphatase; GEF; guanine nucleotide exchange factor; PI(3,4,5)P3; phosphatidylinositol (3,4,5)-trisphosphate; KD; kinase-dead; ApARF6; Aplysia ARF6; A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons

Keywords: Arhgef1; Rho guanine nucleotide exchange factor 1; GEF; guanine nucleotide exchange factor; RhoA; Ras homolog gene family, member A; Rac1; Ras-related C3 botulinum toxin substrate 1; Cdc42; cell division control protein 42; DAPI; 4′,6-diamidino-2-phenyl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Expression of A-kinase anchor protein 13 and Rho-associated coiled-coil containing protein kinase in restituted and regenerated mucosal epithelial cells following mucosal injury and colorectal cancer cells in mouse models

Keywords: AKAP13; A-kinase anchor protein 13; AOM; azoxymethane; CRC; colorectal cancer; DSS; dextran sodium sulfate; ERK; extracellular signal-regulated kinase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GEF; guanine nucleotide exchange region; H&E; hematoxy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The Drosophila DOCK family protein Sponge is required for development of the air sac primordium

Keywords: DOCK; dedicator of cytokinesis; Spg; Sponge; Mbc; Myoblast city; Zir; Zizimin-related; Ziz; Zizimin; GTPase; guanyl triphosphatase; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GDI; guanine nucleotide dissociation inhibitor; SH

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation

Keywords: FGD5; FYVE, RhoGEF and PH domain containing 5; Cdc42; cell division cycle 42; VEGFA; vascular endothelial growth factor A; VEGFR2; vascular endothelial growth factor receptor 2; HMVEC; human microvascular endothelial cells; GEF; guanine nucleotide exchang

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Kalirin, a GEF for Rac1, plays an important role in FSTL-1-mediated glucose uptake in skeletal muscle cells

Keywords: AMPK; GEF; Glucose; Kalirin; Myokine; Small GTPase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts

Keywords: mTORC2; XPLN; SPARC; Idiopathic pulmonary fibrosis; HDAC inhibitor; ADHP; 10-Acetyl-3,7-dihydroxyphenoxazine; DAPI; 4′,6-diamidino-2-phenylindole; ECM; extracellular matrix; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GEF; guanine nucleotide exchan

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

A newly identified Rab-GDI paralogue has a role in neural development in amphibia

Keywords: 1R; first eukaryotic genome duplication; 2R; second eukaryotic genome duplication; AMO; antisense morpholino; A-P; anterior-posterior; cDNA; complementary DNA; DNA; deoxyribonucleic acid; GAP; GTPase activating protein; GDI; guanidine dissociation inhibit

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Polymorphisms in DENND1B gene are associated with asthma and atopy phenotypes in Brazilian children

Keywords: BDCA; markers for distinct subsets of dendritic cells in human peripheral blood; CI; confidence interval; DENN; differentially expressed in normal and neoplastic cells domain; DENND1B; DENN domain containing 1B; ELISA; enzyme-linked immunosorbent assay; e

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

In situ detection of the activation of Rac1 and RalA small GTPases in mouse adipocytes by immunofluorescent microscopy following in vivo and ex vivo insulin stimulation

Keywords: DMEM; Dulbecco's modified Eagle's medium; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GST; glutathione S-transferase; HA; hemagglutinin; m-rac1-KO; muscle-specific rac1 knockout; Myr-p110α; myristoylated p110α; PBS; phosphat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleRas inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1α pathway

Keywords: Metastasis; Ras; Ras inhibitors; LOX; PI3K; HIF-1α; CRC; colorectal cancer; LOX; lysyl oxidase; PI3K; phosphatidylinositol 3-kinase; HIF; hypoxia-inducible factor; GEF; guanine nucleotide exchange factor; GAP; GTPase-activating protein; ECM; extracellula

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Uncertainty propagation of fission product yields to nuclide composition and decay heat for a PWR UO2 fuel assembly

Keywords: Fission yield perturbation; SHARK-X; GEF; SANDY; ENDF/B-VII.1; Decay heat;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Autophagosome Maturation and Fusion

Keywords: Atg; autophagy-related; PI 3-kinase complex; phosphatidyl-inositol 3-kinase complex; PAS; phagophore assembly site; PE; phosphatidylethanolamine; PI3P; phosphatidylinositol-3-phosphate; MTMR; myotubularin; GEF; guanine nucleotide exchange factor; ER; endo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Imaging flow cytometry and GST pulldown assays provide new insights into channel catfish leukocyte immune-type receptor-mediated phagocytic pathways

Keywords: Phagocytosis; Immunoregulatory receptors; Intracellular signaling; Actin polymerization machinery; Imaging flow cytometry; Innate immunity; Channel catfish; Leukocyte immune-type receptors; IpLITR; channel catfish leukocyte immune-type receptor; CYT; cyto

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

The small GTPase Arf6 regulates sea urchin morphogenesis

Keywords: PMCs; primary mesenchyme cells; DVC rod; dorsoventral connecting rod; EMT; epithelial to mesenchymal transition; MASO; antisense morpholino oligonucleotide; GEF; guanine nucleotide exchange factors; GAPs; GTPase activating proteins; Primary mesenchyme cel

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Strategies for development of optogenetic systems and their applications

Keywords: AU1; Aureochrome 1; BLUF; blue-light-utilizing FAD; BphP1; bacterial bathy phytochrome 1; BV; biliverdin IXα; COP1; constitutively photomorphogenic 1; CRY2; cryptochrome 2; CIB1; cryptochrome interacting basic-helix-loop-helix protein 1; CPH1; cyanobacte

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging

Keywords: 8-oxoG; 7,8-dihydro-8-oxoguanine; 8-oxodG; 7,8-dihydro-8-oxo-2′-deoxyguanosine; BER; base excision repair; DNA dsbs; double strand breaks; DNA ssbs; single strand breaks; GEF; guanine nucleotide exchange factor; GOrilla; Gene Ontology enrichment analysi

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

The CLME+ Strategic Action Programme: An ecosystems approach for assessing and managing the Caribbean Sea and North Brazil Shelf Large Marine Ecosystems

Keywords: Large Marine Ecosystems; Caribbean; North Brazil Shelf; Strategic Action Programme; Living marine resources; GEF;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases

Keywords: ADP; adenosine 5′-diphosphate; AgRP; agouti-related peptide; AMPK; 5′-AMP-activated protein kinase; ApnA; diadenosine polyphosphate; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATP; adenosine 5′-triphosphate; BN-PAGE; blue native-p

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

ACAP3, the GTPase-activating protein specific to the small GTPase Arf6, regulates neuronal migration in the developing cerebral cortex

Keywords: Small G protein; Arf6; Arf GAP; ACAP3; Neuronal migration; ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains; Arf; ADP-ribosylation factor; ARNO; Arf nucleotide binding site opener; BCIP; 5-bromo-4-chloro-3-indolyl phosphate; BRAG2; Brefeldin A

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Stretch-induced actomyosin contraction in epithelial tubes: Mechanotransduction pathways for tubular homeostasis

Keywords: ATP; adenosine triphosphate; DAG; diacylglycerol; ECM; extracellular matrix; FAK; focal adhesion kinase; GAP; GTPase activating protein; GDI; guanine dissociation factor; GEF; guanine nucleotide exchange factor; GPCR; G protein coupled receptor; HUVEC; Hu

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Interaction of KRas4b with anionic membranes: A special role for PIP2

Keywords: KRas4b; Nanodisc; Cancer signaling; Lipid specificity; PIP2; CD; Catalytic Domain; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DMPS; 1,2-dimyristoyl-sn-glycero-3-phospho-l-serine; GAP; GTPase activating proteins; GDP; Guanosine diphosphate; GEF; Gu

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

ADP-ribosylation factor-like GTPase 15 enhances insulin-induced AKT phosphorylation in the IR/IRS1/AKT pathway by interacting with ASAP2 and regulating PDPK1 activity

Keywords: ARL15; ASAP2; PDPK1; AKT; Insulin resistance; Phosphorylation; ARL15; ADP-ribosylation factor-like GTPase 15; ARF; ADP-ribosylation factor; ASAP2; ARF-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; GEF; Guanine nucleotide-exchange fac

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

RhoA GTPase oxidation stimulates cell proliferation via nuclear factor-κB activation

Keywords: CA; constitutively active; DMEM; Dulbecco's modified Eagle's medium; DN; dominant negative; GAP; GTPase activating protein; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GDF; GDI displacement factor; GDI; guanine nucleotide dissociation inhibitor; GEF;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Rho-specific Guanine nucleotide exchange factors (Rho-GEFs) inhibition affects macrophage phenotype and disrupts Golgi complex

Keywords: Arg1; Arginase 1; DH-PH domain; the diffuse B-cell lymphoma (Dbl) domain and pleckstrin-homology domain; GDP; guanosine diphosphate; GEF; guanine exchange factor; GM130; 130 kDa cis Golgi matrix protein; GTP; guanosine triphosphate; INF-γ; Interferonγ;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of HC11 mouse breast epithelial cell differentiation by the E-cadherin/Rac axis

Keywords: cRac1; Cellular Rac1; CRIB; Cdc42/Rac-interactive binding; E-cadherin; Epithelial cadherin; ECL; enhanced chemiluminescence; EGF; Epidermal growth factor; GAP; GTPase activating protein; GDP; guanosine 5′-diphosphate; GEF; guanine nucleotide exchange fa

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Role of ADP ribosylation factor6− Cytohesin1−PhospholipaseD signaling axis in U46619 induced activation of NADPH oxidase in pulmonary artery smooth muscle cell membrane

Keywords: Phospholipase D; NADPH oxidase; ADP rybosylation factor; Cytohesin; Thromboxane A2; Pulmonary artery smooth muscle cells; Tp; thromboxane A2 receptor; BFA; brefeldin A; PLD; Phospholipase D; Arf; ADP rybosylation fector; GEF; guanine nucleotide exchange f

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

DOCK8 deficiency: Insights into pathophysiology, clinical features and management

Keywords: Actin; CDC42; Combined immunodeficiency; Dedicator of cytokinesis; DOCK2; DOCK8; Hyper IgE syndrome; Primary immunodeficiency; RAC1; STAT3; AR-HIES; autosomal recessive hyper IgE syndrome; AD-HIES; autosomal dominant hyper IgE syndrome; CDC42; cell divisi

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

The C1 domain of Vav3, a novel potential therapeutic target

Keywords: DAG; diacylglycerol; PKC; protein kinase C; GEF; guanine nucleotide exchange factor; PMA; phorbol 12-myristate 13-acetate; PDBu; phorbol 12,13-dibutyrate; CH domain; calponin homology domain; AD; acidic domain; DH; Dbl homology; PH; Pleckstrin homology; S

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of a novel protein interaction between Elmo1 and Cdc27

Keywords: Elmo; Cdc27; Dock1; Interaction; Efferocytosis; TAMRA; 5-(and-6)-Carboxytetramethylrhodamine; GEF; guanine nucleotide exchange factor; APC; anaphase promoting complex; GST; glutathione S-transferase; TPR; tetratricopeptide repeat; TLC; total cell lysates;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

A negative-feedback loop regulating ERK1/2 activation and mediated by RasGPR2 phosphorylation

Keywords: RasGRP2; ERK1/2 signaling; Negative-feedback loop; Phosphorylation; GEF; CalDAG-GEFI;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Fluorescence bioimaging of intracellular signaling and its clinical application

Keywords: BAPTA-AM; acetoxymethyl ester of 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid; BiFC; bimolecular fluorescence complementation; CML; chronic myeloid leukemia; CFP; cyan-emitting mutant of green fluorescent protein; FRET; Förster resonance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewSearching for the Chokehold of NRAS Mutant Melanoma

Keywords: ERK; extracellular signal-regulated kinase; GEF; guanine nucleotide exchange factor; HRAS; Harvey-rat-sarcoma homolog; KRAS; Kirsten-rat-sarcoma homolog; MAPK; mitogen-activated protein kinase; NRAS; neuroblastoma rat-sarcoma homolog; RAL; retinaldehyde;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Dock10 regulates CD23 expression and sustains B-cell lymphopoiesis in secondary lymphoid tissue

Keywords: ANOVA; analysis of variance; BCR; B-cell receptor; BM; bone marrow; CM; complete medium; DN; double negative; DP; double positive; FO; follicular; GC; germinal center; GEF; guanine nucleotide exchange factor; GEP; gene expression profile; IB; isolation bu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Direct inhibition of oncogenic KRAS by Bacillus pumilus ribonuclease (binase)

Keywords: RAS; Rat sarcoma; GTPase; hydrolase enzyme that can bind and hydrolyze guanosine triphosphate (GTP); Binase; Bacillus pumilus ribonuclease; ERK; extracellular signal-regulated kinases; Guanyl-preferring RNase; small G-proteins; KRAS; GAP; GEF; MAPK/ERK pa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Noonan syndrome-causing genes: Molecular update and an assessment of the mutation rate

Keywords: Molecular etiology; MAP kinase signaling pathways; Mutation rate; Noonan syndrome; PTPN11; RAS family; CDC25; cell division cycle 25; CHD; congenital heart defects; CR; conserved region; CRD; cysteine-rich domain; GAP; GTPase activating protein; GDP; guan

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه