دانلود مقالات ISI درباره Gpcr + ترجمه فارسی

Gigantism: X-linked acrogigantism and GPR101 mutations

Keywords: XLAG; X-linked acrogigantism; GPCR; G protein-coupled receptor; GHRHR; Growth hormone releasing hormone receptor; FoSTeS/MMBIR; Fork stalling and template switching/microhomology-mediated break-induced replication; aCGH; Comparative genomic hybridization

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of the imidazole-derived GPR40 agonist AM-3189

Keywords: GPR40; FFAR1; GPCR; Agonist; Type II diabetes; Insulin secretagogue; AMG 837; AM-3189

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

A relation between osteoclastogenesis inhibition and membrane-type estrogen receptor GPR30

Keywords: RANKL; receptor activator of NF-κB ligand; M-CSF; macrophage colony-stimulating factor; QOL; quality of life; GPCR; G-protein coupled receptor; BMC; bone marrow cell; TRAP; tartrate-resistant acid phosphatase; Osteoclast; Osteoporosis; Flavonoid; Quercet

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Optimization of amide-based EP3 receptor antagonists

Keywords: EP3 receptor; PGE2; GPCR; LipE; Metabolites; P-gp; Indazole;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Impact of purification conditions and history on A2A adenosine receptor activity: The role of CHAPS and lipids

Keywords: GPCR; Lipids; Detergents; Ligand binding; Cholesterol;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

The role of G protein-coupled receptors in cochlear planar cell polarity

Keywords: GPCR; G protein; PCP; Inner ear; Hair cells

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Cross-talk between lysophosphatidic acid receptor 1 and tropomyosin receptor kinase A promotes lung epithelial cell migration

Keywords: LPA; GPCR; RTK; Transactivation; Receptor internalization; Cell migration;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

A class-A GPCR solubilized under high hydrostatic pressure retains its ligand binding ability

Keywords: G protein-coupled receptor; High hydrostatic pressure; Pheromone biosynthesis-activating neuropeptide receptor; Solubilization; Ligand binding ability; AEBSF; 4-(2-aminoethyl)benzensulfonyl fluoride; AP; ambient pressure; CBB; Coomassie Brilliant Blue; CH

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors

Keywords: PDE10a inhibitor; Insulin secretagogues; Type 2 diabetes; GPCR; GSIS; Brain penetration;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

GPCRs of adrenal chromaffin cells & catecholamines: The plot thickens

Keywords: β-Arrestin; Catecholamine secretion; Chromaffin cell; GPCR; GRK2; Signal transduction

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Pervanadate induces Mammalian Ste20 Kinase 3 (MST3) tyrosine phosphorylation but not activation

Keywords: Cys; cysteine; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; GPCR; G protein-coupled receptor; HEK 293; human embryonic kidney 293; HPK1; hematopoietic progenitor kinase 1; MST; mammalian Ste20 kinase; MAP4K; MAP kinase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportERK-dependent brain-derived neurotrophic factor regulation by hesperidin in mice exposed to chronic mild stress

Keywords: BDNF; brain-derived neurotrophic factor; CREB; cAMP-response element binding protein; CMS; chronic mild stress; ERK; extracellular signal-regulated kinase; FST; forced swimming test; GPCR; G-protein-coupled receptor; TrkB; tropomyosin receptor kinase B; H

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewExpression and cellular function of vSNARE proteins in brain astrocytes

Keywords: AQP4; aquaporin 4 water channel; BoNT; botulinum toxin; dnSNARE; dominant negative SNARE; EM; electron microscopy; GLAST; glutamate aspartate transporter; GLT-1; glutamate transporter 1; GPCR; G protein-coupled receptor; KO; knockout; miniSOG; mini single

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Co-expression of silkworm allatostatin-C receptor BNGR-A1 with its cognate G protein subunits enhances the GPCR display on the budding baculovirus

Keywords: GPCR; G protein; Baculovirus; Allatostatin-C; Silkworm;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Kinetic binding and activation profiles of endogenous tachykinins targeting the NK1 receptor

Keywords: Binding kinetics; NK1 receptor; Label-free; Association rate; GPCR; Tachykinin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome

Keywords: AChR; acetylcholine receptor; AdR; adrenergic receptors; ANA; anti-nuclear antibodies; CFS; Chronic Fatigue Syndrome; GPCR; G-protein coupled receptor; POTS; Postural Orthostatic Tachycardia Syndrome; RRTI; Recurrent respiratory tract infections; TG; thyr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Human herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7

Keywords: ACKR; atypical chemokine receptor; CCKAR; cholecystokinin A receptor; CCL; chemokine (CC motif) ligand; CHO; Chinese hamster ovary; CXCL; chemokine (CXC motif) ligand; CX3CL; chemokine (CX3C motif) ligand; EBV; Epstein-Barr virus; ERK; extracellular rec

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

A negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3

Keywords: Relaxin-3; RXFP3; GPCR; Receptor activation; Ligand binding;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Inside story of Group I Metabotropic Glutamate Receptors (mGluRs)

Keywords: Endocytosis; Trafficking; Desensitization; Receptor recycling; GPCR; Metabotropic glutamate receptors; Neurotransmitter receptors

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Ala5-galanin (2-11) is a GAL2R specific galanin analogue

Keywords: BBB; blood-brain barrier; CHO cells; Chinese hamster ovary cells; CNS; central nervous system; EDTA; ethylenediaminetetraacetic acid; FBS; fetal bovine serum; Fmoc; 9-fluorenylmethyloxycarbonyl; FSK; forskolin; GAL1R; Galanin receptor 1; GAL2R; Galanin re

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Role of flotillins in the endocytosis of GPCR in salivary gland epithelial cells

Keywords: Endocytosis; Internalization; GPCR; Flotillin; Lipid-raft; Colocalization;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Sphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs

Keywords: Sphingosine-1-phosphate; GPCR; Cardiac progenitor cells; MRTF-A; RhoA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Is the Canonical RAF/MEK/ERK Signaling Pathway a Therapeutic Target in SCLC?

Keywords: SCLC; ERK1/2; MAPK; GPCR; Signaling; Combination therapy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Novel N-acyl-carbazole derivatives as 5-HT7R antagonists

Keywords: 5-HT7R; Antagonist; N-Acyl-carbazole; Serotonin; Depression; GPCR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Mimotope mimicking epidermal growth factor receptor alleviates mononuclear cell infiltration in exocrine glands induced by muscarinic acetylcholine 3 receptor

Keywords: M3R; muscarinic type 3 receptor; SS; Sjögren's syndrome; EGFR; epidermal growth factor receptor; EL; extracellular loop combination of M3R; NC; N-terminus combination of M3R; GPCR; guanosine-binding protein coupled receptor; LPS; lipopolysaccharide; PDGF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

BRET-based β-arrestin2 recruitment to the histamine H1 receptor for investigating antihistamine binding kinetics

Keywords: H1R; histamine H1 receptor; GPCR; G protein-coupled receptor; NFAT; nuclear factor of activated T-cells; ERK; extracellular signal-regulated kinases; BRET; bioluminescence resonance energy transfer; HEK293T; Human embryonic kidney cells transformed with l

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets

Keywords: G protein-coupled receptor; Regulator of G protein signaling; Pancreatic beta-cell; Insulin secretion; Proliferation; GPCR; G protein-coupled receptors; RGS; Regulators of G-protein Signaling; PTX; Bordetella pertussis toxin; SST; Somatostatin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Recent updates on GPCR biased agonism

Keywords: GPCR; 7TMR; Functional selectivity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research PaperActivation of NPFF2 receptor stimulates neurite outgrowth in Neuro 2A cells through activation of ERK signaling pathway

Keywords: ANOVA; analysis of variance; cAMP; cyclic adenosine monophosphate; GPCR; G-protein-coupled receptor; IBMX; 3-isobutyl-1-methylxanthine; NPFF; FLFQPQRFamide; RF9; 1-adamantanecarbonyl-RF-NH2; (1DMe)NPYF; D-YL(N-Me)-FQPQRF-NH2; MAPK; the mitogen-activated p

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Apelin binding to human APJ receptor leads to biased signaling

Keywords: APJR; human APJ receptor; GPCR; G protein-coupled receptor; AT1; Angiotensin II type I; TM; trans-membrane; Ang; angiotensin; ECL; extra-cellular loop domain; PIPE; Polymerase Incomplete Primer Extension; HBBS; Hank's balanced salt solution; ERK; extra-ce

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleLoss of Gsα impairs liver regeneration through a defect in the crosstalk between cAMP and growth factor signaling

Keywords: cAMP; cyclic adenosine monophosphate; CCl4; carbon tetrachloride; CDK; cyclin-dependent kinase; CREB; cAMP-responsive element-binding protein; Erk; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; Gsα; the stimulatory G protein α

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Regulator of G protein signaling 20 enhances cancer cell aggregation, migration, invasion and adhesion

Keywords: EMT; epithelial-mesenchymal transition; GPCR; G protein-coupled receptor; HINT; histidine triad nucleotide binding protein; RTK; receptor tyrosine kinase; RGS; regulator of G protein signaling; TLR; Toll-like receptor; RGS20; Cancer; Tumorigenesis; Metast

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Biased agonism: An emerging paradigm in GPCR drug discovery

Keywords: Biased ligand; Functional selectivity; GPCR; Drug discovery;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

How Can Mutations Thermostabilize G-Protein-Coupled Receptors?

Keywords: thermostability; GPCR; dynamics; structure

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of the ErbB network by the MIG6 feedback loop in physiology, tumor suppression and responses to oncogene-targeted therapeutics

Keywords: RTK; receptor tyrosine kinase; EGF; epidermal growh factor; EGFR; epidermal growth factor receptor; LRIG1; leucin-rich repeats and immunoglobulin-like domains1; MIG; 6mitogen inducible gene 6; RALT; receptor associated late transducer; ERRFI1; ErbB recept

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Imipramine administration induces changes in the phosphorylation of FAK and PYK2 and modulates signaling pathways related to their activity

Keywords: α1-AR; α1-adrenergic receptor; CaMKII; Ca2 +/calmodulin-dependent protein kinase II; DAG; diacylglycerol; ECM; extracellular matrix; ERK1/2; extracellular signal-regulated kinases 1 and 2; FAK; focal adhesion kinase; GPCR; G-protein coupled receptor; L

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Lipid topogenesis - 35 years on

Keywords: C/EPT; choline/ethanolamine phosphotransferase; CDP; cytidine diphosphate; CDS; CDP-DAG synthase; CL; cardiolipin; DGAT; diacylglycerol acyltransferase; DIPPS; di-myo-inositol-1,3′-phosphate-1′-phosphate synthase; GPCR; G protein-coupled receptor; GPI

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

BPTU, an allosteric antagonist of P2Y1 receptor, blocks nerve mediated inhibitory neuromuscular responses in the gastrointestinal tract of rodents

Keywords: Enteric nervous system; Purinergic neurotransmission; P2Y1 receptor; Allosteric antagonist; α,β-meATP; adenosine 5′-triphosphate; ADPβS; adenosine 5′-[β-thio]diphosphate trilitium salt; ATP; adenosine triphosphate; AUC; area under the curve; BPTU;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The peptidomimetic Lau-(Lys-βNSpe)6-NH2 antagonizes formyl peptide receptor 2 expressed in mouse neutrophils

Keywords: Receptor antagonism; Anti-inflammatory; GPCR; NADPH-oxidase; Reactive oxygen species;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119

Keywords: CREB; cAMP response element-binding protein; EEC; enteroendocrine cell; FAAH; fatty acid amide hydrolase; FBS; Fetal Bovine Serum; GIP; glucose-dependent insulinotropic polypeptide; GLP-1; glucagon-like-peptide 1; GPCR; G protein-coupled receptor; LPC; ly

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of long-term active immunization with the second extracellular loop of human β1- or β3-adrenoceptors in thoracic aorta and mesenteric arteries in Lewis rats

Keywords: AAB; auto-antibody; β1-AAB; auto-antibody to β1-adrenoceptor; β2-AAB; auto-antibody to β2-adrenoceptor; β3-AAB; auto-antibody to β3-adrenoceptor; β1-AB; antibody to β1-adrenoceptor; β3-AB; antibody to β3-adrenoceptor; AR; adrenoceptor; CCRC; cum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Dynamic monitoring of GPER-mediated estrogenic effects in breast cancer associated fibroblasts: An alternative role of estrogen in mammary carcinoma development

Keywords: α-SMA; α-smooth muscle actin; CAF; cancer associated fibroblast; Ca2+; calcium; E2; 17-β-estradiol; ECM; extracellular matrix; EC50; concentration for 50% of maximal effect; EGFR; epidermal growth factor receptor; ER; estrogen receptor; ERK; extracellu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Isolation and characterization of the corticotropin-releasing factor-related diuretic hormone receptor in Rhodnius prolixus

Keywords: AMG; anterior midgut; BAPTA-AM; 1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid; BSA; bovine serum albumin; CT; calcitonin; CAP2b; cardioacceleratory peptide 2b; CNS; central nervous system; CHO; Chinese hamster ovary; CRF; corticotropin-rele

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation

Keywords: DAG; diacylglycerol; PPIns; phosphoinositides; RTK; receptor tyrosine kinase; GPCR; G-protein coupled receptor; Ins(1,4,5)P3; inositol 1,4,5-trisphosphate; PM; plasma membrane; BRET; bioluminescence resonance energy transfer; PLC; phospholipase C; PtdIns(

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular mechanisms of LL-37-induced receptor activation: An overview

Keywords: AMP; antimicrobial peptide; APD; antimicrobial peptide database; IFN; interferon; DC; dendritic cell; NK-cells; natural killer cells; GPCR; G protein-coupled receptor; RTK; receptor tyrosine kinase; LGIC; ligand-gated ion channel; TLR; toll-like receptor;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The CXCL8-CXCR1/2 pathways in cancer

Keywords: CXCL8; C-X-C motif ligand 8; CXCR1; C-X-C chemokine receptor 1; CXCR2; C-X-C chemokine receptor 2; TNFα; tumour necrosis factor α; IL-1β; Interleukin-1β; GPCR; G protein-coupled receptors; MMP; matrix metalloproteinase; IL-8; Interleukin-8; ELR; elast

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

β-arrestins regulate gonadotropin receptor-mediated cell proliferation and apoptosis by controlling different FSHR or LHCGR intracellular signaling in the hGL5 cell line

Keywords: hGL5; FSHR; LHCGR; Apoptosis; GPCR; Arrestin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells

Keywords: Serotonin transporter; Adrenal chromaffin cell; Calcium channel; Exocytosis; Catecholamine; 5-HT receptor; Amperometry; Calcium imaging; GPCR; 8-OH-DPAT; 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol; DMSO; dimethyl sulfoxide; GIRK channel; G protei

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of novel transplantable GPCR recycling motif for drug discovery

Keywords: GPCR; β-Adrenergic receptors; Trafficking; PDZ; SNX27; Confocal microscopy;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Roles of Mas-related G protein-coupled receptor X2 on mast cell-mediated host defense, pseudoallergic drug reactions, and chronic inflammatory diseases

Keywords: G protein-coupled receptor; MRGPRX2; mast cells; host defense peptides; neuropeptides; drug-induced pseudoallergy; chronic urticaria; asthma; C3aR; Anaphylatoxin C3a receptor; CGRP; Calcitonin gene-related peptide; CTMC; Connective tissue mast cell; C

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه