دانلود مقالات ISI درباره هیستون deacetylases + ترجمه فارسی

Histone Deacetylase Inhibitor Potentiates Anticancer Effect of Docetaxel via Modulation of Bcl-2 Family Proteins and Tubulin in Hormone Refractory Prostate Cancer Cells

Keywords: هیستون deacetylases; prostate; prostatic neoplasms; histone deacetylases; docetaxel; apoptosisCI, combination index; HDAC, histone deacetylase; HDACI, HDAC inhibitor; HRPC, hormone refractory prostate cancer; MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-s

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

C-type lectin DC-SIGN: An adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity

Keywords: هیستون deacetylases; (APCs); antigen-presenting cells; (CRD); carbohydrate recognition domain; C(CLRs); C-type lectin receptors; (CBP); CREB-binding protein; (CRD); cysteine-rich domain; (DC-SIGN); dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integri

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Epigenetic regulation of CD8+ T-lymphocyte mediated suppression of HIV-1 replication

Keywords: هیستون deacetylases; Histone deacetylases; CD8+ T-lymphocyte HIV-1 suppression; Virus controllers;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Nε-Modified lysine containing inhibitors for SIRT1 and SIRT2

Keywords: هیستون deacetylases; JPLQJVHFWVRCMD-KWBADKCTSA-N; MEYNFVUTVBJWPP-KWBADKCTSA-N; JABBTCGQJSTXGT-KWBADKCTSA-N; FSMBZPAWSICZTC-YDHLFZDLSA-N; DJWSGCMPYDSWQU-YDHLFZDLSA-N; SOFITECXFFYPLN-YDHLFZDLSA-N; Histone deacetylases; NAD+-dependent deacetylation; Sirtuin inhibitors;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Characterization of gene expression induced by RTN-1C in human neuroblastoma cells and in mouse brain

Keywords: هیستون deacetylases; HDACs; Histone deacetylases; ER; Endoplasmic reticulum; AD; Alzheimer's disease; NOS; nitric oxide synthase; DARPP32; dopamine- and cAMP-regulated phosphoprotein 32 kDa; CAMIIbeta; Ca2+-calmodulin-dependent kinase IIbeta; RTN; reticulon; GRP78; glucose-r

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel Histone deacetylases (HDACs) inhibitors

Keywords: هیستون deacetylases; 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid derivatives; Histone deacetylases; Inhibitor; Synthesis

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Structural basis for sirtuin function: What we know and what we don't

Keywords: هیستون deacetylases; Sirtuins; Histone deacetylases; Structure

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Inhibitors to understand molecular mechanisms of NAD+-dependent deacetylases (sirtuins)

Keywords: هیستون deacetylases; Histone deacetylases; Sirtuins; Inhibitor design

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Histone deacetylases modulate vascular smooth muscle cell migration induced by cyclic mechanical strain

Keywords: هیستون deacetylases; Cyclic mechanical strain; Smooth muscle cells; Migration; Histone deacetylases

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization

Keywords: هیستون deacetylases; Histone deacetylases; Parallel synthesis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Escape mechanisms from antibody therapy to lymphoma cells: Downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation

Keywords: هیستون deacetylases; CD20; Rituximab; Epigenetics; Histone deacetylases; DNA methytransferases

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Agonist-induced nuclear export of GFP-HDAC5 in isolated adult rat ventricular myocytes

Keywords: هیستون deacetylases; Histone deacetylases; ARVM; Adenovirus

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Histone deacetylase inhibitor induced modulation of anti-estrogen therapy

Keywords: هیستون deacetylases; Histone deacetylases; HDAC; HDAC inhibitors; Breast cancer; Estrogen receptor; Progesterone receptor; Anti-estrogen therapy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status

Keywords: هیستون deacetylases; Breast cancer; Estrogen receptor; Valproic acid; Histone deacetylases; Chromatin remodeling

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Histone deacetylase inhibitors that target tubulin

Keywords: هیستون deacetylases; Epigenetics; Histone deacetylases; HDAC6; Sirtuin; Tubulin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Activation of ROS/NF-κB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1β-treated human tracheal smooth muscle cells

Keywords: هیستون deacetylases; Cytokine; Cellular adhesion molecules; NADPH oxidase; Histone acetyltransferases; Histone deacetylases;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Development of a fluorescence polarization based assay for histone deacetylase ligand discovery

Keywords: هیستون deacetylases; HDAC; Histone deacetylases; Suberoylanilide hydroxamic acid; SAHA; Fluorescence polarization; Ligand discovery; High-throughput screening

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

SIRTUIN 1: Regulating the regulator

Keywords: هیستون deacetylases; Sirtuins; SIRT1; Histone deacetylases; Cancer; Metabolic homeostasis; Differentiation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Myostatin induces p300 degradation to silence cyclin D1 expression through the PI3K/PTEN/Akt pathway

Keywords: هیستون deacetylases; MSTN; Myostatin; TGF-β; Transforming growth factor-β; PI3K; Phosphatidylinositol 3-kinase; PTEN; Phosphatase and tensin homolog deleted on chromosome 10; MAPK; Mitogen-activated protein kinase; ERK; Extracelluar signal-regulated kinase; JNK; c-Jun N-ter

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Histone deacetylase inhibitors suppress interleukin-1β-induced nitric oxide and prostaglandin E2 production in human chondrocytes

Keywords: هیستون deacetylases; Chondrocytes; Nitric oxide; Inducible nitric oxide synthase; Prostaglandin E2; Cyclooxygenase-2; Histone deacetylases; Nuclear factor-κBBA, butyric acid; COX-2, cyclooxygenase-2; HDAC, histone deacetylase; IL, interleukin; iNOS, inducible nitric oxide syn

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin

Keywords: هیستون deacetylases; Atrial arrhythmias; Histone deacetylases; Fibrosis; Connexin40; Heart failure

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cells

Keywords: هیستون deacetylases; Histone deacetylases; Proteomics; Colon cancer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides

Keywords: هیستون deacetylases; Histone deacetylases; Chlamydocin; Grubb’s alkene metathesis; Bicyclic tetrapeptide; Inhibitors

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Valproic acid induces polarization, neuronal-like differentiation of a subpopulation of C6 glioma cells and selectively regulates transgene expression

Keywords: هیستون deacetylases; histone deacetylases; epigenetic; brain tumors; gene therapy; oncology; GFAPBDNF, brain-derived neurotrophic factor; BrdU, 5-bromo-2-deoxyuridine; CMV, cytomegalovirus; DAPI, 4,6-diamidino-2-phenylindole; DNMT, DNA methyltransferase; eGFP, enhanced green

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Neural stem cell self-renewal

Keywords: هیستون deacetylases; Neural stem cells; Self-renewal; Transcriptional regulators; Epigenetic control; MicroRNA; Nuclear receptors; Histone deacetylases; Wnt

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Design and evaluation of ‘Linkerless’ hydroxamic acids as selective HDAC8 inhibitors

Keywords: هیستون deacetylases; Histone deacetylases; Hydroxamic acids; HDAC8

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Design of novel histone deacetylase inhibitors

Keywords: هیستون deacetylases; Histone deacetylases; Malonyl benzamides

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

The role of histone deacetylases (HDACs) in human cancer

Keywords: هیستون deacetylases; Histone deacetylases; Cancer; Review

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Vitamin D receptor-mediated suppression of RelB in antigen presenting cells: A paradigm for ligand-augmented negative transcriptional regulation

Keywords: هیستون deacetylases; Vitamin D receptor; Nuclear factor kappa B, RelB; Transcription; Negative regulation; Dendritic cells; Autoimmunity; Histone deacetylases; Retinoic acid receptor X; Immune system; Antigen presentation; Immune tolerance; Co-repressors; Vitamin D analogs;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

HDAC inhibition amplifies gap junction communication in neural progenitors: Potential for cell-mediated enzyme prodrug therapy

Keywords: هیستون deacetylases; Neural progenitor cell; Gene therapy; Bystander effect; Gap junction; Connexin 43; Histone deacetylases; 4-Phenylbutyrate;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors

Keywords: هیستون deacetylases; Epigenetics; Histone acetylation; Histone deacetylases; Nicotinamides; Benzamides

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

MS-275, a potent orally available inhibitor of histone deacetylases-The development of an anticancer agent

Keywords: هیستون deacetylases; AML; acute myeloid leukemia; CLL; chronic lymphocytic leukemia; CPA; cyproterone acetate; CRA; cis-retinoic acid; CTCL; cutaneous T-cell lymphoma; DLT; dose limiting toxicity; EGFR; epithelial cell growth factor receptor; FDA; Food and Drug Administration

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2007 سفارش ترجمه

Trichostatin-A enhances adaptive immune responses to DNA vaccination

Keywords: هیستون deacetylases; CMV, cytomegalovirus; IE1, immediate early protein 1; HDAC, histone deacetylases; TSA, trichostatin-A; Ad5, adenovirus 5; ELISA, enzyme-linked immunosorbent assayDNA vaccine; Cytomegalovirus; Immediate early protein 1; Histone deacetylases; Trichostatin-A

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter

Keywords: هیستون deacetylases; SLC5A8; Butyrate; Histone deacetylases; Colon cancer; Colonic bacteria; Dietary fiber; Short-chain fatty acids

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Histone deacetylase inhibitor Trichostatin A reduces anti-DNA autoantibody production and represses IgH gene transcription

Keywords: هیستون deacetylases; Autoantibody; IgH gene transcription; Trichostatin A; Histone acetylation; Histone deacetylases; IgH promoter; IgH intronic enhancer (Eμ); 3′-IgH enhancers;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

INI1/hSNF5/BAF47 represses c-fos transcription via a histone deacetylase-dependent manner

Keywords: هیستون deacetylases; INI1/hSNF5/BAF47; Repression; c-fos; Transcription; Histone deacetylases;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

The yeast rDNA locus: A model system to study DNA repair in chromatin

Keywords: هیستون deacetylases; CHO; Chinese hamster ovary; CPDs; cyclobutane pyrimidine dimers; CS; Cockayne syndrome; CSB; CS group B; DAHC; histone deacetylases; FACT; facilitates chromatin transcription; GGR; global genomic repair; HAT; histone acetyltransferases; ISWI; imitation sw

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Histone deacetylase inhibitors

Keywords: هیستون deacetylases; Histone deacetylases; Enzymes; Antitumor; Gene expression; p21WAF1,CIP1; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Histone acetylation, chromatin remodelling, transcription and nucleotide excision repair in S. cerevisiae: studies with two model genes

Keywords: هیستون deacetylases; TCR; transcription-coupled repair; GGR; global genome repair; NER; nucleotide excision repair; UV; ultraviolet; TS; transcribed strand; NTS; non-transcribed strand; CPD; cyclobutane pyrimidine dimer; PCR; polymerase chain reaction; LMPCR; ligase mediated

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Chromatin modifier enzymes, the histone code and cancer

Keywords: هیستون deacetylases; Histone code; Cancer; Histone acetylases; Histone deacetylases; Histone methylases; Chromatin

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2005 سفارش ترجمه