دانلود مقالات ISI درباره هیستون deacetylases + ترجمه فارسی

Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells

Keywords: هیستون deacetylases; TSA; Trichostatin A; HCC; hepatocellular carcinoma; lncRNA; long non-coding RNA; qRT-PCR; real-time quantitative reverse transcription PCR; HDAC; histone deacetylases; HDACi; histone deacetylase inhibitors; TUNEL; Terminal deoxynucleotidyltransferasedUTP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Full Length ArticlesImaging epigenetic regulation by histone deacetylases in the brain using PET/MRI with 18F-FAHA

Keywords: هیستون deacetylases; Epigenetics; Histone deacetylases; Positron emission tomography; Brain; Rhesus macaque;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Antidepressants and mood stabilizers effects on histone deacetylase expression in C57BL/6 mice: Brain region specific changes

Keywords: هیستون deacetylases; Depression; Histone deacetylases; Acetylated histone H3; Striatum; Cingulate cortex; Amygdala;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis and biological characterization of spiro[2H-(1,3)-benzoxazine-2,4′-piperidine] based histone deacetylase inhibitors

Keywords: هیستون deacetylases; Histone deacetylases; Privileged scaffolds; Hydroxamates; Antiproliferation; Pharmacokinetics; In vivo antitumor activity;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Design, synthesis and biological evaluation of indeno[1,2-d]thiazole derivatives as potent histone deacetylase inhibitors

Keywords: هیستون deacetylases; Histone deacetylases; HDAC; Hydroxamic acids; Indeno[1,2-d]thiazole; Tricyclic

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Anti-genotoxic effect of the Sargassum dentifolium extracts: Prevention of chromosomal aberrations, micronuclei, and DNA fragmentation

Keywords: هیستون deacetylases; Sargassum dentifolium; Anti-genotoxic; Chromosomal aberration; Comet assay; Micronucleated bone-marrow cells; Histone deacetylases; Cyclophosphamide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

A novel platinum complex of the histone deacetylase inhibitor belinostat: Rational design, development and in vitro cytotoxicity

Keywords: هیستون deacetylases; Platinum; Histone deacetylases; Histone deacetylase inhibitors; Belinostat; Anti-cancer; Cytotoxicity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Edible blue-green algae reduce the production of pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes

Keywords: هیستون deacetylases; apoE−/−; apolipoprotein E knock out; BGA; blue-green algae; BMM; bone marrow-derived macrophages; CBP; CREB-binding protein; CREB; cAMP-response element-binding protein; C-PC; C-phycocyanin; CVD; cardiovascular disease; HAT; histone acetyltransferase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Linear and cyclic glycopeptide as HIV protease inhibitors

Keywords: هیستون deacetylases; HIV-1 protease; Linear and cyclic glycopeptides; Solid and solution peptide synthesis; Molecular docking; AIDS; acquired immunodeficiency syndrome; CTC; 2-chlorotrityl chloride; DCM; dichloromethane; DIPEA; N,N-diisopropyl ethylamine; DMF; N,N-dimethylfor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors: Part II

Keywords: هیستون deacetylases; NZFYYKNDKBXLCQ-UHFFFAOYSA-N; VQSHMXXQPVNIQO-UHFFFAOYSA-N; QZGWUDDYKCXKMW-UHFFFAOYSA-N; BUGVPZATIPVAKF-UHFFFAOYSA-N; QGCRFWXNOBTSDI-UHFFFAOYSA-N; OKWVWKAZWQAOKZ-UHFFFAOYSA-N; MZFLRMTWMOWSNJ-UHFFFAOYSA-N; NMBBNWZQBOQDMK-UHFFFAOYSA-N; KPWBULDSDAGUKU-UHFFFAOY

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Histone deacetylase activity is required for skin Langerhans cell maturation and phagocytosis

Keywords: هیستون deacetylases; Langerhans cells; Phagocytosis; Maturation; Histone deacetylases;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei

Keywords: هیستون deacetylases; HAT; human African trypanosomiasis; VSG; variant surface glycoprotein; HDAC; histone deacetylases; DAC; deacetylases; SAR; Structure-activity relationship; Anti-parasitic activity; Trypanosoma brucei; Histone deacetylase inhibitors; Hydroxamic acids;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Acetylation of sphingosine kinase 1 regulates cell growth and cell-cycle progression

Keywords: هیستون deacetylases; Acetylation; Cell growth; Cell-cycle progression; Sphingosine kinase 1; acetyl-CoA; acetyl coenzyme A; Ad; adenovirus; CBP; CREB-binding protein; CREB; cAMP-response element-binding protein; EGFP; enhanced green fluorescent protein; FBS; fetal bovine seru

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

ABCA1, ABCG1, and SR-BI: Transit of HDL-associated sphingosine-1-phosphate

Keywords: هیستون deacetylases; S1P; sphingosine-1-phosphate; HDL-S1P; HDL-associated S1P; ABCA1; ATP-binding cassette transporter A1; SR-BI; scavenger receptor class B memberI; C1P; ceramide-1-phosphate; HDAC; histone deacetylases; TRAF2; TNF receptor-associated factor 2; SPHK; sphingo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Genetic and Epigenetic Biomarkers of Colorectal Cancer

Keywords: هیستون deacetylases; Colon Cancer; Mutation; Epimutation; Methylation; 5-FU; 5-fluorouracil; APC; adenomatous polyposis coli; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CRC; colorectal cancer; DNMT; DNA methyltransferases; EGFR; epidermal growth fact

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Sensitization of tumor cells by targeting histone deacetylases

Keywords: هیستون deacetylases; Drug resistance; Apoptosis; Histone deacetylases

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of erythromycin on cigarette-induced histone deacetylase protein expression and nuclear factor-κB activity in human macrophages in vitro

Keywords: هیستون deacetylases; Erythromycin; Cigarette smoke extract; Histone deacetylases; Nuclear factor-κB; Proinflammatory cytokine; Chronic obstructive pulmonary disease;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Alcohol-induced serotonergic modulation: The role of histone deacetylases

Keywords: هیستون deacetylases; Alcohol; Histone deacetylases; Serotonin; 5-HT; SK-N-MC; Neurons;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Histone deacetylases and their inhibitors: molecular mechanisms and therapeutic implications in diabetes mellitus

Keywords: هیستون deacetylases; Histone deacetylases; Diabetes mellitus; Histone acetyltransferases; HDAC proteins; HDAC inhibitors

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Histone deacetylases inhibitor Trichostatin A ameliorates DNFB-induced allergic contact dermatitis and reduces epidermal Langerhans cells in mice

Keywords: هیستون deacetylases; Trichostatin A; Histone deacetylases; Allergic contact dermatitis; Langerhans cells; NKT cells; Regulatory T cells

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

SnoN oncoprotein enhances estrogen receptor-α transcriptional activity

Keywords: هیستون deacetylases; ChIP; chromatin immunoprecipitation; ER; estrogen receptor; ERE; estrogen response element; E2; 17-β-estradiol; HA; hemagglutinin; HDAC; histone deacetylases; NBD; nuclear receptor binding domain; SnoN; ski-related novel gene; TGF-ß; transforming growth

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Matrix metalloproteinases: Potential therapy to prevent the development of second malignancies after breast radiotherapy

Keywords: هیستون deacetylases; MMP; Ionizing radiation; Breast cancer; Radiation-induced carcinogenesis; Tumour microenvironment; Tumour progression; Histone deacetylases; Second malignancy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Role for Class I histone deacetylases in multidrug resistance

Keywords: هیستون deacetylases; Histone deacetylases; Multidrug resistance; P-gp; Sp1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Histone deacetylases and cancer

Keywords: هیستون deacetylases; Protein acetylation; Histone deacetylases; Cancer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The HDAC inhibitor depsipeptide transactivates the p53/p21 pathway by inducing DNA damage

Keywords: هیستون deacetylases; Ara-C; cytarabine; ATM; ataxiatelangiectasia-mutated; ATR; ATM- and Rad3-related; CAT; catalase; CHK2; the checkpoint kinase 2; CK1; casein kinase 1; DHE; dihydroethidium; DNA-PK; DNA-dependent serine/threonine protein kinase; Grx; glutaredoxin; HAT; hist

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Valproic acid induces the glutamate transporter excitatory amino acid transporter-3 in human oligodendroglioma cells

Keywords: هیستون deacetylases; DHK; dihydrokainate; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DTT; 1,4-dithiothreitol; EAAC1; excitatory amino acid carrier 1; EBSS; Earle's balanced salt solution; EAAT1-2-3; excitatory amino acid transporter 1-2-3; FBS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Early life stress triggers sustained changes in histone deacetylase expression and histone H4 modifications that alter responsiveness to adolescent antidepressant treatment

Keywords: هیستون deacetylases; HDAC; histone deacetylase; IMS; infant maternal separation; SFR; standard facility reared; EPM; Elevated Plus Maze; FST; Forced Swim Test; Early life stress; Mouse; Adolescent development; Frontal cortex; Histone deacetylases; Histone H4 acetylation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Epigenetic deregulation of the COX pathway in cancer

Keywords: هیستون deacetylases; AKR1B1; aldo-keto reductase family 1 member B1; AOM; azoxymethane; COX; cycloxigenase; COX-1 (also known as PTGS1); cycloxigenase 1; COX-2 (also known as PTGS2); cycloxigenase 2; Coxibs; selective COX-2 inhibitors; CRTH2 (also known as DP2); chemoattrac

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by endoplasmic reticulum stress

Keywords: هیستون deacetylases; ATF6; activating transcription factor 6; BFA; brefeldin A; CaM; calmodulin; 15dPGJ2; 15-deoxy-Δ12,14-prostaglandin J2; eIF2α; eukaryotic translation initial factor 2α; ER; endoplasmic reticulum; GAS; gamma-activated sequence; HAT; histone acetyltransfe

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Histone modifications as a pathogenic mechanism of colorectal tumorigenesis

Keywords: هیستون deacetylases; AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

HDAC modulation and cell death in the clinic

Keywords: هیستون deacetylases; Histone deacetylases; Histone deacetylase inhibitors; Cancer; Clinical trials;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Redox signaling and histone acetylation in acute pancreatitis

Keywords: هیستون deacetylases; Acute inflammation; Histone acetyltransferases; Histone deacetylases; cAMP; MAPK; PP2A; Protein tyrosine phosphatases; Free radicals

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

Ca2+-calmodulin-dependent protein kinase II regulation of cardiac excitation-transcription coupling

Keywords: هیستون deacetylases; Ca-Calmodulin dependent protein kinase; histone deacetylase; calcineurin; β-AR; β-adrenergic receptor; Ca-CaM; Ca-bound CaM; CaM; calmodulin; CaMKII; Ca2+-calmodulin-dependent protein kinase II; CaN; calcineurin; E-C; excitation-contraction; ET; endothe

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Epigenetics and autosomal dominant polycystic kidney disease

Keywords: هیستون deacetylases; Epigenetic; Autosomal dominant polycystic kidney disease; Histone deacetylases; HDAC inhibitor; α-Tubulin; Epidermal growth factor receptor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation

Keywords: هیستون deacetylases; PCa; prostate cancer; Nrf2; nuclear factor erythroid-2 (NF-E2) related factor-2; CUR; curcumin; BGS; bisulfite genomic sequencing; MeDIP; methylation DNA immunoprecipitation; anti-mecyt; anti-methycytosine; HDAC; histone deacetylases; DNMTs; DNA methyltra

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus

Keywords: هیستون deacetylases; Social defeat; Individual differences; Response to novelty; Histones; Histone deacetylases; Creb binding protein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Design, synthesis and biological evaluation of tyrosine-based hydroxamic acid analogs as novel histone deacetylases (HDACs) inhibitors

Keywords: هیستون deacetylases; Tyrosine derivatives; Histone deacetylases; Inhibitor; Synthesis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of different exercise protocols on histone acetyltransferases and histone deacetylases activities in rat hippocampus

Keywords: هیستون deacetylases; histone acetylation; HAT; HDAC; neuroprotection; exercise; rats; BDNF; brain-derived neurotrophic factor; EXE; exercised group; HAT; histone acetyltransferases; HDAC; histone deacetylases; SED; sedentary group;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Design, synthesis and biological evaluation of novel histone deacetylase inhibitors based on virtual screening

Keywords: هیستون deacetylases; Histone deacetylases; Virtual screening; Non-hydroxamate; MS-275

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Three 4-letter words of hypertension-related cardiac hypertrophy: TRPC, mTOR, and HDAC

Keywords: هیستون deacetylases; Left ventricular hypertrophy; Cardiac remodeling; Mechanosensitive channels; Cardiac myocyte; Histone deacetylases; Hypertension;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

HIV-1 Tat upregulates expression of histone deacetylase-2 (HDAC2) in human neurons: Implication for HIV-associated neurocognitive disorder (HAND)

Keywords: هیستون deacetylases; Histone deacetylases; HIV-associated neurocognitive disorder; Tat protein; Synaptic plasticity; Primary human neurons; SK-N-MC neuroblastoma cell line

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

After the grape rush: Sirtuins as epigenetic drug targets in neurodegenerative disorders

Keywords: هیستون deacetylases; Sirtuins; Histone deacetylases; Neurodegenerative disorders; Alzheimer; Parkinson’s disease; Huntington’s disease; Resveratrol

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biological activity of splitomicin analogs targeted at human NAD+-dependent histone deacetylases (sirtuins)

Keywords: هیستون deacetylases; HITGYSJTYLSBLD-UHFFFAOYSA-OBenzimidazole; Histone deacetylases; Ligand efficiency; Sirtuins; Splitomicin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

cAMP stimulation of StAR expression and cholesterol metabolism is modulated by co-expression of labile suppressors of transcription and mRNA turnover

Keywords: هیستون deacetylases; ACTH; adrenocorticotropic hormone; AKAP 121; A-kinase anchor protein 121; AUF1; AU-rich RNA binding factor 1; AURE-BPs; AURE-binding proteins; C/EBP β; CCAAT-enhancer-binding protein; CBP; CREB binding protein; CDK7; cyclin-dependent kinase 7; ChIP; chro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Psychopharmacology: A house divided

Keywords: هیستون deacetylases; ASICs; acid-sensing ion channels; ADs; antidepressants; APs; antipsychotics; βARs; beta-adrenergic receptors; BDNF; brain-derived neurotrophic factor; CRS; chronic restraint stress; CDS; chronic social defeat stress; CREB; cyclic-AMP response-element-bin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Design, synthesis and primary activity assay of tripeptidomimetics as histone deacetylase inhibitors with linear linker and branched cap group

Keywords: هیستون deacetylases; 1,4-Dithia-7-azaspiro[4,4]nonane-8-carboxylic acid derivatives; Histone deacetylases; Inhibitor; Synthesis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of histone acetylation in the hippocampus of chronically stressed rats: a potential role of sirtuins

Keywords: هیستون deacetylases; epigenetics; chronic stress; hippocampus; histone deacetylases; depression; sirtuinsCVS, chronic variable stress; DG, dentate gyrus; HATs, histone acetyltransferases; HDACs, histone deacetylases; H3, histone 3; H4, histone 4; NaB, sodium butyrate; NAD+, n

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Role of Notch and its oncogenic signaling crosstalk in breast cancer

Keywords: هیستون deacetylases; 4T1 cells; mouse mammary cancer cell line; ADAM; a disintegrin and metalloprotease; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; ANK; ankyrin; Axin2; the Axin-related protein; BALB/c; an albino, laboratory-bred strain of the house mouse; Bcl-2; B-

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Estructura y función del ADN y de los genes II. Tipos de alteraciones de la función del gen por procesos epigenéticos

Keywords: هیستون deacetylases; Epigenética; Metilación; Alteración de la cromatina; Micro-ARN; Imprinting; Histonas deacetilasas; DietilestilbestrolEpigenetic; Methylation; Chromatin alteration; Micro-RNA; Imprinting; Histone deacetylases; Diethylstilbestrol

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Las terapias epigenéticas, más allá de los biológicos en el tratamiento de la artritis reumatoide

Keywords: هیستون deacetylases; Metilación del Genoma; Histona-deacetilasas; Citoquinas; Muerte Celular; ReprogramaciónGenome methylation; Histone deacetylases; Cytokines; Cell death; Reprogramming

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه