
Long range epigenetic silencing is a trans-species mechanism that results in cancer specific deregulation by overriding the chromatin domains of normal cells
Keywords: اصلاح هیستون; Gene silencing; DNA methylation; Colorectal cancer; Chromatin marks; Histone modification; Long range epigenetic silencing; Cell differentiationLRES, Long range epigenetic silencing; ChIP, Chromatin immunoprecipitation; ISC, Intestinal stem cells