دانلود مقالات ISI درباره Hmg-Coa + ترجمه فارسی

Statins activate a mitochondria-operated pathway of apoptosis in breast tumor cells by a mechanism regulated by ErbB2 and dependent on the prenylation of proteins

Keywords: FPP; farnesylpyrophosphate ammonium salt; GGPP; geranylgeranylpyrophosphate; PARP; poly-(ADP-ribose) polymerase; HMG-CoA; hydroxymethylglutaryl-Coenzyme A; Statin; Apoptosis; Bcl-2; ErbB2; Mitochondria; Prenylation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Dual mode of HMG-CoA reductase inhibition on dendritic cell invasion

Keywords: ADMA; asymmetric dimethyl l-arginine; ATV; atorvastatin; CMFDA; 5-chloromethylfluorescein diacetate; FPP; farnesyl pyrophosphate; FTI; farnesyl-transferase inhibitor; GGP; geranylgeranyl pyrophosphate; GGTI; geranylgerany-transferase inhibitor; HMEC-1; im

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells

Keywords: HMG-CoA; Statin; TSA; Apoptosis; RhoA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Leptin Regulates Gallbladder Genes Related to Gallstone Pathogenesis in Leptin-Deficient Mice

Keywords: ABC; ATP-binding cassette; ACh; acetylcholine; CCK; cholecystokinin; HMG-CoA; 3-hydroxy 3-methylglutaryl coenzyme A; Ig; immunoglobulin; JAK; Janus kinase; NPY; neuropeptide Y; PCR; polymerase chain reaction; SMC; smooth muscle cell; STAT; signal transcri

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of the ethanol extract of the roots of Brassica rapa on glucose and lipid metabolism in C57BL/KsJ-db/db mice

Keywords: Brassica rapa; Glucose tolerance; Insulin resistance; Glucose regulating enzymes; Lipid regulating enzymes; Type 2 diabetes; ACAT; acyl CoA:cholesterol acyltransferase; CPT; carnitine palmitoyl transferase; db/db mice; C57BL/KsJ-db/db mice; G6Pase; glucos

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Toward “Pain-Free” Statin Prescribing: Clinical Algorithm for Diagnosis and Management of Myalgia

Keywords: AE; adverse event; AERS; Adverse Event Reporting System; CI; confidence interval; CK; creatine kinase; CoQ10; coenzyme Q10; CYP; cytochrome P; FDA; Food and Drug Administration; HDL-C; high-density lipoprotein cholesterol; HMG-CoA; 3-hydroxy-3-methylgluta

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Research ReportLipid-lowering drugs in the MPTP mouse model of Parkinson's disease: Fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not

Keywords: HMG-CoA; 3-hydroxy 3-methyl glutaryl co-enzyme A; MAO; monoamine oxidase; MPP+; 1-methyl-4-phenyl pyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; PPAR; peroxisome proliferator-activated receptor; ROS; reactive oxyg

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Asymmetric Dimethylarginine Determines the Improvement of Endothelium-Dependent Vasodilation by Simvastatin

Keywords: ADMA; asymmetric dimethylarginine; eNOS; endothelial nitric oxide synthase; FMD; flow-mediated dilation; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; LDL; low-density lipoprotein; NO; nitric oxide; SR; sustained release;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Effects of Statins on Renal Function

Keywords: ALLIANCE; Aggressive Lipid-Lowering Initiation Abates New Cardiac Events; CAD; coronary artery disease; CARE; Cholesterol and Recurrent Events; CI; confidence interval; CKD; chronic kidney disease; ESRD; end-stage renal disease; GFR; glomerular filtration

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Simvastatin prolongs survival times in prion infections of the central nervous system

Keywords: Prion; Scrapie; Therapy; Simvastatin; Neurodegenerative diseases; Neuroinflammation; Cholesterol; Cholesterol synthesis; 3-Hydroxymethyl-3-glutaryl coenzyme A reductase; HMG-CoA; Inhibitor; Multiple sclerosis; EAE; Alzheimer’s disease; Lipid metabolism; A

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

The Effect of Statins in Heart Failure: Beyond its Cholesterol-Lowering Effect

Keywords: Inflammation; HMG-CoA; G-proteins; Cardiomyopathy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Disfunción endotelial

Keywords: Endotelio; Cardiovascular; Aterosclerosis; Óxido nítrico; Endothelium; Cardiovascular disease; Atherosclerosis; Nitric oxide; ADMA; dimetilarginina asimétrica; ADP; adenosín difosfato; bFGF; factor de crecimiento de fibroblastos básico; CAM; molécul

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Preoperative statin therapy is associated with reduced cardiac mortality after coronary artery bypass graft surgery

Keywords: 16; 23; 30; 31; ACE; angiotensin-converting enzyme 4; ACS; acute coronary syndromes; CABG; coronary artery bypass graft; CI; confidence intervals; CPB; cardiopulmonary bypass; DOS; date of surgery; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; IREF; Isc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

The Forgotten Majority

Keywords: HDL; high-density lipoprotein; HMG-CoA; 3-hydroxy-3-methlyglutaryl coenzyme A; LDL; low-density lipoprotein;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibition of β-oxidative respiration is a therapeutic window associated with the cancer chemo-preventive activity of PPARγ agonists

Keywords: PPARγ; peroxisome proliferator activated receptor gamma; TZD; thiazolidinediones; ATP; adenosine triphosphate; ROS; reactive oxygen species; NADPH2; methylenetetrahydrofolate reductase; HMG-CoA; hydroxymethylglutaryl CoA; TRO; troglitazone; TMZ; trimetaz

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Identification of a functional DNA binding site for the SREBP-1c transcription factor in the first intron of the human caspase-2 gene

Keywords: bHLH; basic helix-loop-helix; FAS; fatty acid synthase; HMG-CoA; 3-hydroxy-3-methylglutaryl Coenzyme A; LDLr; low-density lipoprotein receptor; SRE; sterol regulatory element; SREBP; sterol regulatory element binding protein; Human caspase-2; SREBP; L

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Skipping of exon 2 and exons 2 plus 3 of HMG-CoA lyase (HL) gene produces the loss of beta sheets 1 and 2 in the recently proposed (beta-alpha)8 TIM Barrel model of HL

Keywords: HMG-CoA; 3-hydroxy-3-methylglutaryl-Co-enzyme A; HMG-CoA lyase (HL); (beta-alpha)8 TIM Barrel; HMGCL; Exon skipping; Splicing variants; 3-Hydroxy-3-methylgluraric aciduria;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular-regulated kinase-1/-2

Keywords: statin; neuroprotection; signal transduction; ECL; enhanced chemoluminescence; eNOS; endothelial NO synthase; ERK; extracellular-regulated kinase; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; iNOS; inducible NO synthase; JNK; Jun kinase; LDF; laser Dop

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Three-dimensional quantitative structure (3-D QSAR) activity relationship studies on imidazolyl and N-pyrrolyl heptenoates as 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) inhibitors by comparative molecular similarity indices analysis (CoMSIA)

Keywords: 3D-QSAR; HMG-CoA; Imidazolyl heptenoates; N-Pyrolyl heptenoates;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Effect of simvastatin on the oxidation of native and modified lipoproteins

Keywords: Apo I; apolipoprotein I; BHT; butylated hydroxytoluene; CHD; coronary heart disease; CRP; C-reactive protein; EDTA; ethylenediaminetetraacetic acid; HDL; high-density lipoprotein; HMG-CoA; 3-hydroxy-3-methylglutaryl-coenzyme A; LDL; low-density lipoprotei

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Effect of atorvastatin upon platelet activation in hypercholesterolemia, evaluated by flow cymetry

Keywords: ADP; adenosin diphosphate; LDL-C; low-density lipoproteins cholesterol; HDL-C; high-density lipoproteins cholesterol; TC; total cholesterol; GPIIb/IIIa*; GPII/IIIa in its active form; CD62; P-selectin; PS; phosphatidylserine; CD63; glycoprotein 53; HMG-CO

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

The ACAT inhibitor avasimibe increases the fractional clearance rate of postprandial triglyceride-rich lipoproteins in miniature pigs

Keywords: ACAT; acyl coenzyme A: cholesterol acyltransferase; apo; apolipoprotein; AUC; area under the curve; ER; endoplasmic reticulum; FCR; fractional clearance rate; HDL; high density lipoprotein; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; HPLC; high perfor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Suppression of Endothelial Progenitor Cells in Human Coronary Artery Disease by the Endogenous Nitric Oxide Synthase Inhibitor Asymmetric Dimethylarginine

Keywords: ADMA; asymmetric dimethylarginine; CAD; coronary artery disease; CFU; colony forming unit; dil-ac-LDL; 1,1′-dioctadecyl-3,3,3′,3-tetramethyl-indocarbocyanine perchlorate labeled acetylated low-density lipoprotein; eNOS; endothelial nitric oxide syntha

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

The Potential Relevance of the Multiple Lipid-Independent (Pleiotropic) Effects of Statins in the Management of Acute Coronary Syndromes

Keywords: ACS; acute coronary syndromes; CAD; coronary artery disease; CRP; C-reactive protein; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA); ICAM; intercellular adhesion molecule; IL; interleukin; LDL-C; low-density lipoprotein cholesterol; NO; nitric

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NFκB ligand (RANKL) or tumor necrosis factor-α (TNF-α)

Keywords: pOC; preosteoclast; RANKL; receptor activator of NFκB ligand; M-CSF; macrophage colony-stimulating factor; GGTI; geranylgeranyl transferase inhibitor; GGOH; geranylgeraniol; FTI; farnesyl transferase inhibitor; TRAP; tartrate-resistant acid phosphatase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation

Keywords: FCS; fetal calf serum; FOH; farnesol; FPP; farnesyl pyrophoshate; GGOH; geranylgeraniol; GGPP; geranylgeranyl pyrophosphate; HMG-CoA; 3-hydroxy-3-methyl-glutaryl coenzyme A; MEM; minimum essential medium; MVA; mevalonate; PBS; phosphate buffered saline; P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Suppression of Wolffia arrhiza growth by brassinazole, an inhibitor of brassinosteroid biosynthesis and its restoration by endogenous 24-epibrassinolide

Keywords: BR; brassinosteroid; Brz; brassinazole; Clo; clomazone; DMAPP; dimethylallyl diphosphate; epiBL; 24-epibrassinolide; HMG-CoA; hydroxymethylglutaryl CoA; IPP; isopentenyl pyrophosphate; MEP; 2-methylerythriol 4-phosphate; Mev; mevinolin; MVA; mevalonic aci

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Deficiency of PPARα disturbs the response of lipogenic flux and of lipogenic and cholesterogenic gene expression to dietary cholesterol in mouse white adipose tissue

Keywords: NEFA; non-esterified fatty acid; TAG; triacylglycerol; FAS; fatty acid synthase; ACC; acetyl CoA carboxylase; SREBP; sterol regulatory binding protein; PPAR; peroxisome proliferator-activated receptor; LXR; liver-X receptor; LDL; low-density lipoprotein;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

High cholesterol absorption efficiency and rapid biliary secretion of chylomicron remnant cholesterol enhance cholelithogenesis in gallstone-susceptible mice

Keywords: Acat2; acyl-CoA:cholesterol acyltransferase gene 2; FPLC; fast performance liquid chromatography; HDL; high density lipoprotein; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; LDL; low density lipoprotein; QTL; quantitative trait locus; VLDL; very low de

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Dietary toxicity of calcium β-hydroxy-β-methyl butyrate (CaHMB)

Keywords: ANOVA; analysis of variance; BW; body weight; CaHMB; calcium β-hydroxy-β-methyl butyrate; CFR; Code of Federal Regulations; CK; creatine phosphokinase; EPA; eicosapentaenoic acid; FDA; Food and Drug Administration; GLP; good laboratory practices; HMB; Î

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Statins potentiate the IFN-γ-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells

Keywords: C/EBP-β; CAAT-enhancer-binding protein-β; cPLA2; cytosolic phospholipase A2; DRB; 5,6-Dichloro-1-β-d-ribofuranosylbenzimidazole; ELISA; enzyme linked immunosorbent assay; ERK; extracellular signal-regulated kinase; FCS; fetal calf serum; FPP; farnesyl

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

RNA interference: From gene silencing to gene-specific therapeutics

Keywords: RNAi; siRNA; shRNA; Disease; Validation; Therapy; AAV; adeno-associated virus; ABCA1; ATP-binding cassette, subfamily A, member 1; Bcl-2; B-cell chronic lymphocytic leukemia/lymphoma 2; BCR-ABL; breakpoint cluster region-protooncogene tyrosine-protein kin

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2005 سفارش ترجمه

Modulation of hepatic and renal drug metabolizing enzyme activities in rats by subchronic administration of farnesol

Keywords: AHMC; 3-[2-(diethylamino)ethyl]-7-hydroxy-4-methylcoumarin hydrochloride; AMMC; 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin; BHT; butylated hydroxytoluene; CAR; constitutive androstane receptor; CYP or P450; cytochrome P450; DCPIP

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2005 سفارش ترجمه