دانلود مقالات ISI درباره Hsqc + ترجمه فارسی

Apela exhibits isoform- and headgroup-dependent modulation of micelle binding, peptide conformation and dynamics

Keywords: AR; apelin receptor (APJ); CCSD; combined chemical shift displacement; CD; circular dichroism; CSI; chemical shift index; DANGLE; Dihedral Angles from Global Likelihood Estimates; DOSY; diffusion ordered spectroscopy; DPC; dodecylphosphocholine; DSS; 2,2-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Structural profiling of wax biopolymer from Pinus roxburghii Sarg. needles using spectroscopic methods

Keywords: COSY; proton correlation spectroscopy; HSQC; heteronuclear single quantum coherence; HMBC; heteronuclear multiple bond correlation; TOCSY; proton total correlation spectroscopy; eV electron Volt; EI electron ionization; Wax; Biomacromolecule; Pinus roxbur

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Structure and Dimerization of IreB, a Negative Regulator of Cephalosporin Resistance in Enterococcus faecalis

Keywords: NOE; nuclear Overhauser enhancement; NOESY; NOE spectroscopy; PCA; protein-fragment complementation assay; mDHFR; murine dihydrofolate reductase; TMP; trimethoprim; ts; temperature-sensitive; MHB; Mueller Hinton broth; HSQC; heteronuclear single quantum c

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

A Residue Specific Insight into the Arkadia E3 Ubiquitin Ligase Activity and Conformational Plasticity

Keywords: TGF-β; transforming growth factor beta; R-Smads; receptor Smads; Ub; ubiquitin; RING; really interesting new gene; HSQC; heteronuclear single quantum coherence; APSY; automated projection spectroscopy; NOE; nuclear Overhauser effect; WT; wild-type; CSP;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Quick, sensitive serial NMR experiments with Radon transform

Keywords: Radon transform; Multidimensional spectroscopy; HSQC; Variable temperature;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Improvements, extensions, and practical aspects of rapid ASAP-HSQC and ALSOFAST-HSQC pulse sequences for studying small molecules at natural abundance

Keywords: ASAP; HSQC; Fast NMR experiments; Steady state signal intensities; Polarization recovery; Non-uniform sampling; Broadband homouclear decoupling; BIRD; CLIP; Coupling constants; Shaped pulses; Water diluted samples;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Biochemical and Structural Analyses of Two Cryptic Esterases in Bacteroides intestinalis and their Synergistic Activities with Cognate Xylanases

Keywords: CE; carbohydrate esterase; HPAEC-PAD; high-performance anion-exchange chromatography with pulsed amperometric detection; HSQC; heteronuclear single quantum coherence; LB; lysogeny broth; pNP; para-nitrophenyl; Bacteroides intestinalis; human microbiome; f

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Salt-Mediated Oligomerization of the Mouse Prion Protein Monitored by Real-Time NMR

Keywords: moPrP; mouse prion protein; CTD; C-terminal domain; NTR; N-terminal region; α1; alpha helix 1; β2; beta-strand 2; α2; alpha helix 2; α3; alpha helix 3; HX; hydrogen-exchange; HSQC; heteronuclear single quantum coherence; CSP; chemical shift perturbati

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Optimized decoupling schemes in ultrafast HSQC experiments

Keywords: Ultrafast NMR; Adiabatic decoupling; HSQC; Interleaving artifacts;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Enzymatic and acidic degradation of high molecular weight dextran into low molecular weight and its characterizations using novel Diffusion-ordered NMR spectroscopy

Keywords: EPS; exopolysaccharide; FTIR; Fourier-transform infrared; SEM; scanning electron microscopy; NMR; nuclear magnetic resonance spectroscopy; 2D NMR; two dimensional nuclear magnetic resonance spectroscopy; DOSY; diffusion-ordered spectroscopy; COSY; homonuc

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

A structural and functional study of Gln147 deamidation in αA-crystallin, a site of modification in human cataract

Keywords: Cataract; αA-crystallin; Deamidation; Ageing; Post-translational modification; αAc; αA-crystallin; αBc; αB-crystallin; ADH; alcohol dehydrogenase; DEAE; Diethylaminoethane; DTT; Dithiothreitol; HSQC; heteronuclear single quantum coherence; MALS; mult

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Cobalt-based paramagnetic probe to study RNA-protein interactions by NMR

Keywords: NCp7; Nucleocapsid protein 7; HSQC; Heteronuclear single quantum coherence; PRE; Paramagnetic resonance enhancement; TLC; Thin layer chromatography; NMR; Nuclear magnetic resonance; RNA; Ribonucleic acid; A; Adenosine; C; Cytidine; U; Uridine; G; Guanosin

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Acinetobacter baumannii K11 and K83 capsular polysaccharides have the same 6-deoxy-l-talose-containing pentasaccharide K units but different linkages between the K units

Keywords: 6dTal; 6-deoxytalose; Atr; acetyltransferase; COSY; correlation spectroscopy; CPS; capsular polysaccharide; dTDP; deoxythymidine diphosphate; GLC; gas-liquid chromatography; Gtr; glycosyltransferase; HMBC; heteronuclear multiple-bond correlation; HSQC; he

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Solution conformations of a linked construct of the Zika virus NS2B-NS3 protease

Keywords: Inhibitor; NMR spectroscopy; NS2B-NS3 protease; Pseudocontact shifts; Zika; bZiPro; Zika virus NS2B-NS3 protease expressed in two individual parts; eZiPro; Zika virus NS2B-NS3 protease expressed with an enzymatic cleavage site between NS2B and NS3pro; gZi

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and in vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes

Keywords: Quinoline; Fluorination; Phosphodiesterase 5; Radiotracer; Positron emission tomography; AD; alzheimer's disease; AllocCl; allyl chloroformate; ATR; attenuated total reflectance; cAMP; cyclic adenosine 3′,5′-monophosphate; cGMP; cyclic guanosine 3′,

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of CYP443D1 (CYP74 clan) of Nematostella vectensis as a first cnidarian epoxyalcohol synthase and insights into its catalytic mechanism

Keywords: DES; divinyl ether synthase; AOS; allene oxide synthase; HPL; hydroperoxide lyase; EAS; epoxyalcohol synthase; 9-H(P)OD; (9S,10E,12Z)-9-hydro(pero)xy-10,12-octadecadienoic acid; 9-H(P)OT; (9S,10E,12Z,15Z)-9-hydro(pero)xy-10,12,15-octadecatrienoic acid; γ

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Galloylquinic acid derivatives from Copaifera langsdorffii leaves display gastroprotective activity

Keywords: Galloylquinic acid; Phenol; Copaiba; Gastroprotection; Adenocarcinoma; Ulcer; HPLC; high-performance liquid chromatography; LC-MS; liquid chromatography coupled to mass spectrometry; NMR; nuclear magnetic resonance; HSQC; heteronuclear single quantum cohe

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Structural analysis of rebaudioside A derivatives obtained by Lactobacillus reuteri 180 glucansucrase-catalyzed trans-α-glucosylation

Keywords: Stevia rebaudiana; Sweetener; Steviol glycosides; Carbohydrate; NMR spectroscopy; Glycobiotechnology; FID; free induction decay; FWHM; full width at half maximum; GLC-EI-MS; gas-liquid chromatography electron impact mass spectrometry; HPAEC; high-pH anion

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Analysis of DOM phototransformation using a looped NMR system integrated with a sunlight simulator

Keywords: Nuclear magnetic resonance spectroscopy; DOM; Photolysis; In situ; Diffusion-edited NMR; COSY; HSQC;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Structural Analysis of Heparin-Derived 3-O-Sulfated Tetrasaccharides: Antithrombin Binding Site Variants

Keywords: antithrombin-binding site; heparin-derived tetrasaccharides; anticoagulant activity; heparin lyase; structure-activity relationship; AT; antithrombin III; UA; uronic acid; IdoA; iduronic acid; GlcA; β-D-glucuronic acid; GlcN; α-d-glucosamine; STs; sulfo

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase

Keywords: Ocimum sanctum; HIV-1; RNase H; Reverse transcriptase; Triterpenes; Ferulic acid derivatives; AIDS; Acquired Immunodeficiency Syndrome; DCM; dichloromethane; DMAP; 4-dimethylaminopyridine; DP; DNA polymerase; DQF-COSY; Double Quantum Filtered-COrrelation

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Two dimensional NMR spectroscopy for molecular characterization of soil organic matter: Application to boreal soils and litter

Keywords: Soil organic matter; Molecular characterization; DMSO-extracts; 2D NMR; HSQC; Carbon inputs; Lignin; Polysaccharides;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Structural insights into the molecular function of human [2Fe-2S] BOLA1-GRX5 and [2Fe-2S] BOLA3-GRX5 complexes

Keywords: Grxs; glutaredoxins; GSH; glutathione; wt; wilde-type; DTT; dithiothreitol; HSQC; Heteronuclear Single-Quantum Correlation; Iron-sulfur protein; GRX5; BOLA1; BOLA3; Iron metabolism; Glutaredoxin;

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2017 سفارش ترجمه

NMR studies of the non-haem Fe(II) and 2-oxoglutarate-dependent oxygenases

Keywords: 2OG; 2-Oxoglutarate; BBOX; γ-Butyrobetaine hydroxylase; CODD; C-terminal oxygen-dependent degradation domain; COSY; Correlation spectroscopy; DSBH; Double-stranded β-helix; EFE; Ethylene-forming enzyme; FIH; Factor-inhibiting hypoxia-inducible factor; H

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2017 سفارش ترجمه

Structural and mechanistic insights into Mycothiol Disulphide Reductase and the Mycoredoxin-1-alkylhydroperoxide reductase E assembly of Mycobacterium tuberculosis

Keywords: AhpE; alkyl hydroperoxide reductase subunit E; DTT; dithiothreitol; EDTA; ethylenediamine-tetraacetic acid; HADDOCK; High Ambiguity Driven DOCKing; HSQC; Heteronuclear Single Quantum Correlation; Mrx-1; Mycoredoxin-1; NUS; non-uniform sampling; PMSF; phen

دانلود رایگان متن کامل مقاله ISI 67 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperSoluble expression of disulfide-bonded C-type lectin like domain of human CD93 in the cytoplasm of Escherichia coli

Keywords: CTLD; C-type lectin like domain; DTNB; 5,5′-dithiobis-2-nitrobenzoic acid; DTT; dithiothreitol; E. coli; Escherichia coli; EDTA; ethylene diamine tetra-acetic acid; EGF; epidermal growth factor; HSQC; hetero-nuclear single quantum correlation; hTNF-α;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Acetophenone derivatives from a freshwater fungal isolate of recently described Lindgomyces madisonensis (G416)

Keywords: CHCl3; chloroform; CH3OH; methanol; CH3CN; acetonitrile; NMR; nuclear magnetic resonance; HRESIMS; high-resolution electrospray ionization mass spectrometry; HPLC; high-performance liquid chromatography; HMBC; heteronuclear multiple bond coherence; HSQC;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Human SLC26A4/Pendrin STAS domain is a nucleotide-binding protein: Refolding and characterization for structural studies

Keywords: hPDS; Human pendrin polypeptide; IVS; Intrinsic variable sequence; HSQC; Heteronuclear single quantum correlation spectroscopy; CD; Circular dichroism; MS; Mass spectroscopy; SLC26A4; STAS domain; IVS; Protein refolding; NMR; Fluorescence;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis, spectral and structural studies of alkyl 2-(3-alkyl-2,6-diarylpiperidin-4-ylidene)hydrazinecarboxylate derivatives: Crystal and molecular structure of methyl 2-(3-methyl-2,6-diphenylpiperidin-4-ylidene)hydrazinecarboxylate

Keywords: Hydrazinecarboxylate; HSQC; HMBC; Single crystal XRD

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Comparative study of lignin characteristics from wheat straw obtained by soda-AQ and kraft pretreatment and effect on the following enzymatic hydrolysis process

Keywords: Soda-AQ pretreatment; Kraft pretreatment; Lignin; HSQC; Enzymatic hydrolysis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Combining biochemical with 1H NMR-based metabolomics approach unravels the antidiabetic activity of genipin and its possible mechanism

Keywords: BUN; blood urea nitrogen; CRE; creatinine; COSY; correlation spectroscopy; DM; diabetes mellitus; DMA; dimethylamine; DMG; dimethylglycine; DN; diabetic nephropathy; EPG; endogenous glucose production; FBG; fasting blood glucose; 3-HB; 3-hydroxybutyrate;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Spirostanol saponins from Chinese onion (Allium chinense) exert pronounced anti-inflammatory and anti-proliferative activities

Keywords: Chinese onion; Allium chinense; Spirostanol saponins; Anti-inflammatory; Antiproliferative; Laxogenin (PubChem CID: 10950057); Neogitogenin (PubChem CID: 44630243); A549; human lung cancer cells; CNE-1; human nasopharyngeal carcinoma; DEPT; distortionless

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Blocking the interaction between S100A9 and RAGE V domain using CHAPS molecule: A novel route to drug development against cell proliferation

Keywords: S100A9; S100 calcium-binding protein A9; RAGE; the receptor for advanced glycation end products; HSQC; heteronuclear single quantum correlation; HADDOCK; high ambiguity driven docking; CHAPS; 3-[(3-holamidopropyl)dimethylammonio] -1-propanesulfonate; E.co

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases

Keywords: Tankyrase; PARP; 2-Arylquinazolin-4-one; Wnt; Hydrophobic cavity; ADP; adenosine diphosphate; Bn; benzyl; Cbz; benzyloxycarbonyl; DMAP; 4-dimethylaminopyridine; EDC; N′-ethyl-N-3-(dimethylaminopropyl)carbodiimide; ES; electrospray; HMBC; heteronuclear m

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems

Keywords: Abz-AFPF-pNA; aminobenzoyl-Ala-Phe-Pro-Phe-4-nitroanilide; CsA; cyclosporine A; CypD; mitochondrial cyclophilin D (gene name: PPIF, UniProt ID: P30405); GST; glutathione S-transferase; HSP; heat-shock protein; HSQC; heteronuclear single-quantum correlatio

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

The Interaction Mode of the Acidic Region of the Cell Cycle Transcription Factor DP1 with TFIIH

Keywords: DBD; DNA-binding domain; GAL4 DBD; DBD of GAL4; HSQC; heteronuclear single quantum coherence; LZ; leucine zipper; MB; marked box; TAD; transactivation domain; pRB; retinoblastoma protein; PH; pleckstrin homology; WT; wild-type; NOE; nuclear Overhauser eff

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

CommunicationSalt-inducible Protein Splicing in cis and trans by Inteins from Extremely Halophilic Archaea as a Novel Protein-Engineering Tool

Keywords: PTS; protein trans-splicing; GB1; the B1 domain of IgG binding protein G; HSQC; heteronuclear single quantum coherence; TM; transmembrane; CTD; C-terminal domain; IMAC; immobilized metal chelating; TCEP; tris(2-carboxyethyl)phosphine; CPS; conditional pro

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Signaling States of a Short Blue-Light Photoreceptor Protein PpSB1-LOV Revealed from Crystal Structures and Solution NMR Spectroscopy

Keywords: LOV; light-oxygen-voltage; PAS; Per-ARNT-Sim; FMN; flavin mononucleotide; 2D; two-dimensional; HSQC; heteronuclear single-quantum coherence; NOE; nuclear Overhauser enhancement; τm; rotational correlation time; DSS; 2,2-dimethyl-2-silapentane-5-sulfo

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Role of the σ54 Activator Interacting Domain in Bacterial Transcription Initiation

Keywords: RNAP; RNA polymerase; DBD; DNA binding domain; NtrC1C; NtrC1 central domain construct; AID; activator interacting domain; CBD; core binding domain; A.a.; Aquifex aeolicus; E.c.; Escherichia coli; HSQC; heteronuclear single quantum coherence; HMQC; heteron

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Quantitative, equal carbon response HSQC experiment, QEC-HSQC

Keywords: HSQC; Q-HSQC; QEC-HSQC; Quantitative NMR; qNMR;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Precise and rapid isotopomic analysis by 1H-13C 2D NMR: Application to triacylglycerol matrices

Keywords: HSQC; Isotopic profile; Metabolomic profile; Triacylglycerol; Fast 2D NMR;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه

Ptaquiloside from bracken (Pteridium spp.) inhibits tumour-infiltrating CD8+ T cells in HPV-16 transgenic mice

Keywords: Ptaquiloside; Human papillomavirus; Cancer; Bracken; CD8+ T cells; BPV; Bovine Papillomavirus; CTL; Cytotoxic T Lymphocytes; FASL; FAS Ligand; FcγR; Fragment crystallisable gamma Receptor; H&E; Haematoxylin & Eosin; HPV; Human Papillomavirus; HSQC; Heter

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular interaction of δ-conopeptide EVIA with voltage-gated Na+ channels

Keywords: COSY; correlation spectroscopy; DG; distance geometry; DIEA; N,N-diisopropylethylamine; Fmoc; 9-fluorenylmethoxycarbonyl; GSH; glutathione reduced; GSSG; glutathione oxidized; HBTU; O-(benzotriazol-1-yl)-N,N,N′,N′-tetramethyl-uronium-hexafluorophospha

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Antibacterial effects of Alchornea cordifolia (Schumach. and Thonn.) Müll. Arg extracts and compounds on gastrointestinal, skin, respiratory and urinary tract pathogens

Keywords: ATCC; American type culture collection; CC; column chromatography; CFU; colony forming units; CHCl3; chloroform; COSY; correlation spectroscopy; DCM; dichloromethane; DEPT; distortionless enhancement by polarisation transfer; DMSO; dimethyl sulfoxide; EtO

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Sesquiterpenes and a monoterpenoid with acetylcholinesterase (AchE) inhibitory activity from Valeriana officinalis var. latiofolia in vitro and in vivo

Keywords: 13C NMR; 13C nuclear magnetic resonance; 1D NMR; 1 dimension nuclear magnetic resonance; 1H-1H COSY; 1H-1H correlated spectrometry; 1H NMR; 1H nuclear magnetic resonance; 2D NMR; 2 dimension nuclear magnetic resonance; Ach; acetylcholine; AchE; acetyl

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Nemorubicin and doxorubicin bind the G-quadruplex sequences of the human telomeres and of the c-MYC promoter element Pu22

Keywords: doxo; doxorubicin, alias adriamycin; nemo; nemorubicin; daunomycins; doxorubicin and all its derivatives; NMR; nuclear magnetic resonance; NOESY; nuclear Overhauser effect spectroscopy; TOCSY; total correlation spectroscopy; HSQC; Heteronuclear single qua

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

NMR spectroscopy with compact instruments

Keywords: Compact NMR; NMR spectroscopy; Product control; Reaction monitoring; 2D NMR; 1D; one-dimensional; 2D; two-dimensional; CDCl3; deuterated chloroform; COSY; correlation spectroscopy; DEPT; distortion-less enhancement by polarization transfer; EO; ethylene o

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Development, synthesis and structure-activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei

Keywords: Mip; macrophage infectivity potentiator; PPIase; peptidyl-prolyl cis/trans isomerase; LpMip; L. pneumophila Mip; BpMip; B. pseudomallei Mip; SAR; structure-activity relationship; HSQC; Heteronuclear Single Quantum Coherence; NMM; N-methylmorpholine; DIP

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Tacrine-(hydroxybenzoyl-pyridone) hybrids as potential multifunctional anti-Alzheimer's agents: AChE inhibition, antioxidant activity and metal chelating capacity

Keywords: Hydroxybenzoyl-pyridones; Tacrine; Anti-neurodegeneratives; Anti-AChE activity; Anti-oxidant activity; Metal chelation; Aβ; amyloid-β; ACh; acetylcholine; AChE; acetylcholinesterase; AChI; acetylthiocholine iodide; AD; Alzheimer's disease; BuChE; butyry

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2016 سفارش ترجمه

New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties

Keywords: Cinnamic-based hybrids; Antioxidants; Neuroprotectants; Neurogenic agents; Human cholinesterases; Human monoamine oxidases; AChE; acetylcholinesterase; AD; Alzheimer's disease; βA; beta-amyloid peptide; BACE-1; beta-site amyloid precursor protein cleav

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2016 سفارش ترجمه