Keywords: کلیه جنین انسان; Biphalin; Opioid receptors; MOR/DOR/KOR agonist; Synergistic analgesic effect; Cyclic peptides; Acm; acetamidomethyl; ACN; acetonitrile; BBB; blood brain barrier; Boc; t-butyloxycarbonyl; BOP; (benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluoro
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Keywords: کلیه جنین انسان; AD; Alzheimer's disease; PPs; polyphenols; EGCG; epigallocatechin gallate; NFTs; neurofibrillary tangles; ACh; acetylcholine; Aβ; amyloid-beta; APP; amyloid precursor protein; PS-1; presenilin-1; PS-2; presenilin-2; AChE; acetylcholine esterase; Cdk5;
Keywords: کلیه جنین انسان; CuAAC; Copper-Catalyzed Azide-Alkyne Cycloadditions; PhSH; thiophenol; alloc; allylcarbamate group; DAPI; 4â²,6-diamidine-2â²-phenylindole; EtBr; ethidium bromide; TON; turnover number; GSH; glutathione; PBS; phosphate buffered saline; TPP; triphenylp
Keywords: کلیه جنین انسان; Anti-diabetic; PPARγ; Gene expression; Molecular docking; Thiazolidinedione; Pyrazole; ALP; alkaline phosphatase; ALT; alanine transaminase; AMPK; 5â² adenosine monophosphate-activated protein kinase is an enzyme; AST; aspartate transaminase; DMEM; Dulb
Keywords: کلیه جنین انسان; AITC; allyl isothiocyanate; AMTB; N-(3-aminopropyl)-2-{[(3-methylphenyl) methyl]oxy}-N-(2-thienylmethyl) benzamide hydrochloride; EC50; 50% effective concentration; HEK; human embryonic kidney; HEPES; N-2-hydroxyethyl-piperazine-2-ethanonesulfonic acid; T
Keywords: کلیه جنین انسان; ATCC; American Type Culture Collection; CFU; colony forming unit; DMEM; Dulbecco's modified eagle's medium; ELISA; enzyme-linked immunoassay; FBS; Fetal Bovine Serum; GC; chocolate agar; HEK; human embryonic kidney; IC; inhibitory concentration; INT; p-io
Keywords: کلیه جنین انسان; Synthetic biology; Cell-based device; Synthetic receptor; Immunotherapy; Robustness; Intercellular variation; CAR; Chimeric antigen receptor; GLP-1; Glucagon-like peptide-1; HEK; Human embryonic kidney; IL; Interleukin; iPSC; Induced pluripotent stem cell
Keywords: کلیه جنین انسان; EU; European Union; FDA; Food and Drug Administration; EMA; European Medicines agency; HEK; human embryonic kidney; shRNA; short hairpin RNA; siRNA; small interference RNA; α-gal; galactose-α1,3-galactose; Neu5Gc; N-glycolylneuraminic acid; IgG; Immunog
Keywords: کلیه جنین انسان; ACTB; beta actin; BBB; blood-brain barrier; CA; central area; CCL2; chemokine (CC motif) ligand 2; CLDN5; claudin 5; DMSO; dimethyl sulfoxide; EU; endotoxin unit; GAPDH; glycerinaldehyde-3-phosphate-Dehydrogenase; HEK; human embryonic kidney; HPA; hypotha
Keywords: کلیه جنین انسان; AF; Alexa Fluor 647; BAPTA; 1,2-bis(o-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid; CaM; calmodulin; CBD; calmodulin binding protein; CCD; charge-coupled device; DMEM; Dulbecco's Modified Eagle's Medium; FCS; fluorescence correlation spectroscopy; F
Keywords: کلیه جنین انسان; [Ca2+]i; intracellular calcium concentration; VDCCs; voltage-dependent Ca2Â + channels; ATP; adenosine triphosphate; RyR; ryanodine receptors; BKCa; large conductance calcium-activated K+ channels; KATP; ATP-sensitive K+ channels; KIR; inward rectifier K+
Keywords: کلیه جنین انسان; AA; arachidonic acid; AKR; aldo-keto reductase; AOS; allene oxide synthase; CX; carbon numbers; COX; cyclooxygenase; cPGES; cytosolic PGE synthase; cPLA2; cytosolic phospholipase A2; CYP; cytochrome P450; DGLA; dihomo-γ-linolenic acid; DP; prostaglandin
Keywords: کلیه جنین انسان; 2-APB; 2-aminoethoxydiphenyl borate;; ATP; adenosine triphosphate; CT; C-terminal tail; Cx(s); connexin(s); dsRNA; double-stranded RNA; EL(s); extracellular loop(s); GA; glycyrrhetinic acid; GABA; γ-amino butyric acid; GJ(s); gap junction(s); GJIC; gap j
Keywords: کلیه جنین انسان; A1AT; alpha-1-antitrypsin; ADCC; antibody-dependent cellular cytotoxicity; AEM; adenovirus expression medium; CHO; Chinese hamster ovary; sDHB; super-dihydroxybenzoic acid; Fc; fragment crystallizable; GalNAc; N-acetylgalactosamine; GlcNAc; N-acetylglucos
Keywords: کلیه جنین انسان; BBB; blood-brain barrier; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; CGRP; calcitonin gene-related peptide; CHO; Chinese hamster ovary; CLR; calcitonin receptor-like receptor; CNS; central nervous system; DAB; 3,3â²-diaminobenzidi
Keywords: کلیه جنین انسان; AKH; adipokinetic hormone; CHO; Chinese hamster ovary; Crypα; cell adhesion molecule-like tyrosine phosphatase α; Endo H; Endoglycosidase H; ENG; endoglin/CD105; HEK; human embryonic kidney; IMAC; immobilized metal affinity chromatography; MBP; maltose-
Keywords: کلیه جنین انسان; BBB; blood-brain barrier; Boc; tert-butyloxycarbonyl; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; DAMGO; H-Tyr-d-Ala-Gly-NMePhe-Gly-ol; DCM; dichloromethane; DIEA; N,N-diisopropylethylamine; DOR; δ-opioid receptor; DPDPE; Tyr-c(d
Keywords: کلیه جنین انسان; BSE; bovine spongiform encephalopathy; CAP; CEVEC'samniocyte production; CEF; chicken embryo fibroblast; DNA; deoxyribonucleic acid; EP; European Pharmacopeia; FBS; fetal bovine serum; GCCP; good cell culture practice; GMP; good manufacturing practices; H
Keywords: کلیه جنین انسان; ALS; amyotrophic lateral sclerosis; ANOVA; analysis of variance; DAB; 3,3â²-diaminobenzidine tetrahydrochloride; DAPI; 4â²,6-diamidino-2-phenylindole; DM; degenerative myelopathy; GP; general proprioceptive; GST; glutathione S-transferase; HEK; human em
Keywords: کلیه جنین انسان; Ac; acetyl; ACTH; adrenocorticotropic hormone; Alloc; allyloxycarbonyl; Boc; t-butoxycarbonyl; BSA; bovine serum albumin; DIC; N,Nâ²,-diisopropylcarbodiimide; DIEA; diisopropylethylamine; DMEM; Dulbecco's Modified Eagle Medium; DMF; N,N-dimethylformami
Keywords: کلیه جنین انسان; APC; antigen presenting cell; BPL; beta-propiolactone; CI; confidence interval; DS; double stranded; GMC; geometric mean concentration; HA; haemagglutinin; HEK; human embryonic kidney; HI; haemagglutination inhibition assay; MPH; monovalent pooled harvest
Keywords: کلیه جنین انسان; AR; androgen receptor; DMEM; Dulbecco's minimal essential medium; FCS; fetal calf serum; GR; glucocorticoid receptor; GRE; glucocorticoid response element; GST; glutathione S-transferase; HEK; human embryonic kidney; IPTG; isopropyl-β-d-thiogalactoside
Keywords: کلیه جنین انسان; aCSF; artificial cerebrospinal fluid; MDMA; 3,4-methylenedioxy-N-methylamphetamine; HEK; human embryonic kidney; ACMD; Advisory Council on the Misuse of Drugs; FCV; fast cyclic voltammetry; ANOVA; analysis of variance; DAT; dopamine transporter; NET; nora
Keywords: کلیه جنین انسان; AZ; antizyme; AZBE; antizyme-binding element; AZIN; antizyme inhibitor; ERGIC; endoplasmic reticulum-Golgi intermediate compartment; ODC; ornithine decarboxylase; GDT_TS; global distance test total score; HA; hemagglutinin; HEK; human embryonic kidney; PA
Keywords: کلیه جنین انسان; AP; action potential; ArgMe; arginine methylation; bmp; beats per minute; CFP or YFP; cyan or yellow fluorescent protein; co-IP; co-immunoprecipitation; FRET; Förster resonance energy transfer; HEK; human embryonic kidney; IP; immunoprecipitation; LI-I
Keywords: کلیه جنین انسان; IL; interleukin; IL-R; IL-receptor; IFN-γ; interferon-γ; TNF-α; tumor necrosis factor α; STAT; signal transducer and activator of transcription; NF-κB; nuclear factor-κB; JAK; Janus kinase; HEK; human embryonic kidney; MOG35-55; myelin oligodendro
Keywords: کلیه جنین انسان; AP; action potential; APD; AP duration; ATX-II; anemonia sulcata toxin 2; DMSO; dimethylsulfoxide; ECG; electrocardiogram; eSC; embryonic stem cell; FP; field potential; FPD; FP duration; HEK; human embryonic kidney; hERG; human ether-a-go-go-related gene
Keywords: کلیه جنین انسان; LSD; lysergic acid diethylamide; METH; (+)methamphetamine; MDMA; 3,4-methylenedioxymethylamphetamine; MDPV; 3,4-methylenedioxypyrovalerone; mephedrone; 4-methyl-N-methylcathinone; methylone; 3,4-methylenedioxy-N-methylcathinone; 4-FMC; 4-fluoromethcathino
Tas2r125 functions as the main receptor for detecting bitterness of tea catechins in the oral cavity of mice
Keywords: کلیه جنین انسان; Catechins; ECg; Bitter taste receptor; Tas2r125; [Ca2+]i; intracellular calcium concentration; CvP; circumvallate papillae; ECg; (â)-epicatechin gallate; EGCg; (â)-epigallocatechin gallate; HEK; human embryonic kidney;
Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and mice
Keywords: کلیه جنین انسان; Asn; asparagine; Bisection; bisecting GlcNAc; Fc; fragment crystallizable; FcγR; Fc gamma receptor; GlcNAc; N-acetylglucosamine; HEK; human embryonic kidney; hFcγR; human FcγR; hIgG; human IgG; IgG; immunoglobulin G; mFcγR; -mouse FcγR; mIgG; mouse
The role of TRPV4 in fibrosis
Keywords: کلیه جنین انسان; α-SMA; α-smooth muscle actin; aa; amino acids; AHF; alcohol/high fat diet; AIP4; atrophin-interacting protein 4; ANK; ankyrin; ARS-L; arachidonate-like recognition sequence; ASL; airway surface liquid; BKCa; Ca2 +-dependent K+; [Ca2 +]i; intracellular
Differential regulation of tefluthrin and telmisartan on the gating charges of INa activation and inactivation as well as on resurgent and persistent INa in a pituitary cell line (GH3)
Keywords: کلیه جنین انسان; AP; action potential; HEK; human embryonic kidney; I-V; current versus voltage; INa; voltage-gated Na+ current; INa(P); persistent INa; INa(R); resurgent INa; λ; rate constant; LIM; d-limonene; NaV channel; voltage-gated Na+ channel; Ran; ranolazine; S
Molecular and cellular basis of ornithine δ-aminotransferase deficiency caused by the V332M mutation associated with gyrate atrophy of the choroid and retina
Keywords: کلیه جنین انسان; OAT; ornithine δ-aminotransferase; PLP; pyridoxal 5â²-phosphate; GA; gyrate atrophy; L-Orn; L-ornithine; GSA; glutamic-γ-semialdehyde; α-KG; α-ketoglutarate; P5C; pirroline-5-carboxylate; OATwt; OAT wild-type; OATV332M; OAT bearing the V332M mutation
HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation
Keywords: کلیه جنین انسان; DNMT1; DNA-methyltransferase 1; FOXO; Forkhead box O transcription factors; GST; glutathione S-transferase; HBP1; HMG-box protein 1; HEK; human embryonic kidney; HMG; high mobility group; HPLC; high performance liquid chromatography; KD; kinase dead; MS;
Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo
Keywords: کلیه جنین انسان; DHE; dehydroevodiamine; IKr; rapid delayed rectifier current; APD; action potential duration; EAD; early afterdepolarization; cAVB; chronic atrioventricular block; TdP; Torsade de Pointes arrhythmia; hiPSC-CM; human induced pluripotent stem cell-derived c
Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration
Keywords: کلیه جنین انسان; Small molecule screening; PGC-1a; PGC-1alpha; PGC-1alpha1; Protein stabilization; UCP1; Mitochondrial respiration; Brown adipose tissue; C/EBP; CCAAT-enhancer-binding proteins; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; HEK; human embryon
Pathogenic IgG4 autoantibodies from endemic pemphigus foliaceus recognize a desmoglein-1 conformational epitope
Keywords: کلیه جنین انسان; Cell adhesion molecule; Desmosome; IgG4 autoantibody; Skin autoimmunity; FS; fogo selvage; Dsg; desmoglein; Dsc; desmocollin; EC; extracellular; PF; pemphigus foliaceus; HEK; human embryonic kidney;
Integrating plant and animal biology for the search of novel DNA damage biomarkers
Keywords: کلیه جنین انسان; ARP; actin related protein; ASK; Arabidopsis SPK1-like; At; Arabidopsis thaliana; ATAF; arabidopsis transcription activation factor; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR-interacting protein; BARD; BRCA1-associated RING
Membrane cholesterol modulates STEAP2 conformation during dynamic intracellular trafficking processes leading to broad subcellular distribution
Keywords: کلیه جنین انسان; BSA; bovine serum albumin; DIC; differential interference contrast; ER; endoplasmic reticulum; FAD; flavin adenine dinucleotide; GFP; green fluorescent protein; HEK; human embryonic kidney; mAb; monoclonal antibody; MOPS; 3-(N-morpholino)propanesulfonic a
Deficiency in GnRH receptor trafficking due to a novel homozygous mutation causes idiopathic hypogonadotropic hypogonadism in three prepubertal siblings
Keywords: کلیه جنین انسان; CDGP; constitutional delay of growth and puberty; CHO; Chinese hamster ovary; E2; estradiol; ER; endoplasmic reticulum; FSH; follicle-stimulating hormone; GnRH; gonadotropin-releasing hormone; HEK; human embryonic kidney; H-P-G axis; hypothalamic-pituit
TRPM7 functions in non-neuronal and neuronal systems: Perspectives on its role in the adult brain
Keywords: کلیه جنین انسان; TRPM7; transient receptor potential melastatin like 7; PI3K; phosphatidyl inositol 3-kinase; Akt; serine-threonine kinase; S6K1; S6 kinase 1; mTORC; mammalian target of rapamycin complex; HEK; human embryonic kidney; TRPM6; transient receptor potential me
A systematic analysis of the expression of the anti-HIV VRC01 antibody in Pichia pastoris through signal peptide optimization
Keywords: کلیه جنین انسان; Pichia pastoris / Komagataella phaffi; Broadly neutralizing antibody; VRC01; Signal peptide; 2A sequence; AA; α-amylase; α-MF; α-mating factor; αK; α-mating factor K; αKS; α-mating factor KS; αT; α-mating factor T; AOX1; alcohol oxidase 1; AP; al
SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas
Keywords: کلیه جنین انسان; 4E-BP; 4E binding protein; AKT; v-akt murine thymoma viral oncogene homolog; BCC; basal cell carcinoma; BCNS; basal cell nevus syndrome; CCND1; cyclin D1; GLI; glioma-associated oncogene homolog; HEK; human embryonic kidney; ITRA; itraconazole; mTOR; mamm
Development of potent and proteolytically stable human neuromedin U receptor agonists
Keywords: کلیه جنین انسان; Neuromedin U (NMU); NMU-8; Neuromedin U receptor agonists; Plasma stability; 1â²Nal; 1â²-naphtylalanine; 2â²Nal; 2â²-naphtylalanine; 7-OH-Tic; 7-hydroxy-L-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; ACN; acetonitrile; AUC; area under the curve;
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction
Keywords: کلیه جنین انسان; Anti-Influenza; PA-PB1; RdRp; Amino acid coupling; SPPS; Diphenyl-pyridine; AcOEt; Ethyl acetate; CC50; Half maximal cytotoxic concentration; cRNA; complementar RNA; DCM; dichloromethane; DDQ; 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone; DIPEA; N,N-Diisopro
Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy
Keywords: کلیه جنین انسان; d-amino acid oxidase (DAAO); Propiverine; Peroxisomal import; Protein trafficking; Cytosolic and nuclear protein mislocalization and accumulation; Co-immunoprecipitation (Co-IP); Nano-LC-ESI-MS/MS; Immunohistochemistry (IHC); hDAAO, rDAAO; human and rat d
The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase
Keywords: کلیه جنین انسان; AZ; antizyme; AZIN; antizyme inhibitor; DFMO; α-difluoromethylornithine; DMEM; Dulbecco's Modified Eagle Medium; HEK; human embryonic kidney; LDC; leucine decarboxylase; ODC; ornithine decarboxylase; PLP; pyridoxal phosphate; Polyamine; Isopentylamine; A
Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner
Keywords: کلیه جنین انسان; AJ; adherence junction; APC; Allophycocyanin; BBB; blood-brain barrier; BECs; brain endothelial cells; CNS; central nervous system; DAPT; N-[N-(3,5-Difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl ester; DLL1, -3 and -4; Delta-like family ligand 1, -
Sumoylation and ubiquitylation crosstalk in the control of ÎNp63α protein stability
Keywords: کلیه جنین انسان; SUMO; Small Ubiquitin-like Modifier; Ub; ubiquitin; SHFM-IV; Split Hand Foot Malformation; Ubc9; ubiquitin carrier protein 9; p14ARF; p14 Alternative Reading Frame; GAM-1; Gallus Anti Mortem 1; GADD45; The Growth Arrest and DNA Damage; DLX5; Distal-Less H
Comprehensive identification of proteins binding to RNA G-quadruplex motifs in the 5â² UTR of tumor-associated mRNAs
Keywords: کلیه جنین انسان; RNA G-quadruplexes; Post-transcriptional regulation; RNA-binding proteins; Translational regulation; Cancer; CD; Circular dichroism; FDR; False discovery rate; FF Luc; firefly luciferase; FTMS; Fourier transform mass spectrometry; GO; Gene Ontology; GQ; G