دانلود مقالات ISI درباره Ic50 + ترجمه فارسی

Baohuoside-1 inhibits activated T cell proliferation at G1-S phase transition

Keywords: APCs; antigen presenting cells; B1; baohuoside-1; CsA; cyclosporin A; Con A; concanavalin A; cdks; cyclin-dependent kinases; EBV; Epstein-Barr virus; IC50; 50% inhibitory concentration; FK506; tacrolimus; FACS; fluorescence activated cell sorting; Ig; i

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Antioxidant properties of two gallotannins isolated from the leaves of Pistacia weinmannifolia

Keywords: ROS; reactive oxygen species; ABTS; 2,2′-azinobis(3-ethylbenzothiozoline-6-sulphonic acid) diammonium salt; DPPH; 1,1-dipheny-2-picrylhydrazyl; PC; l-α-phosphatidylcholine; BSA; bovine serum albumin; AAPH; 2,2′-azobis(2-amidinopropane)dihydrochloride

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Virus-inducible reporter genes as a tool for detecting and quantifying influenza A virus replication

Keywords: BHK-21; baby hamster kidney cells; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; FluA; influenza A virus; GFP; green fluorescent protein; h; hours; hpi; hours post-infection; IC50; 50% inhibitory concentration; LAC; La Crosse virus; l

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Ultrasound-assisted extraction methodology as a tool to improve the antioxidant properties of herbal drug Xiao-chia-hu-tang

Keywords: ABTS; 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid); DPPH; 1,1-diphenyl-2-picryl hydrazyl; EDTA; ethylenediaminetetraacetic acid; GA; glycyrrhizic acid; IC50; 50% inhibition concentration; MDA; malondialdehyde; PHC; potassium hexacyanoferrate;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Anticoagulant action of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, in umbilical cord and adult plasma: an in vitro examination

Keywords: aPTT; activated partial-thromboplastin time; AT; antithrombin; CT0; clotting time without melagatran; CTm; concentrations of melagatran; DTI; direct thrombin inhibitor; EDTA; ethylenediaminetetra-acetic acid; ETP; endogenous thrombin potential; F; coagula

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection

Keywords: 5-OHdC; 5-hydroxydeoxycytidine; RT; reverse transcriptase; PBMCs; peripheral mononuclear cells; FMDV; foot-and-mouth disease virus; CC50; concentration needed to kill 50% of the cells; IC50; 50% inhibitory concentration; TCID50; tissue culture dose for 50

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Anti-inflammatory profile of dehydrocostic acid, a novel sesquiterpene acid with a pharmacophoric conjugated diene

Keywords: AA; arachidonic acid; BOC; N-tertbutoxycarbonyl-l-alanine-p-nitrophenyl ester; COX; cyclooxygenase; DMSO; dimethyl sulfoxide; EDTA; ethylenediametetraacetic acid; HBSS; Hanks' balanced salt solution; HETE; hydroxyeicosatetraenoic acid; IC50; inhibitory

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Platelet-activating factor acetylhydrolase: selective inhibition by potent n-alkyl methylphosphonofluoridates

Keywords: AChE; acetylcholinesterase; AH; acetylhydrolase; BDPO; benzodioxaphosphorin 2-oxide; CPO; chlorpyrifos oxon; DFP; diisopropyl fluorophosphate; ED50; dose inhibiting 50% of enzyme activity; IC50; concentration inhibiting 50% of enzyme activity; DMSO; dimet

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Relationship between cucurbitacins reversed-phase high-performance liquid chromatography hydrophobicity index and basal cytotoxicity on HepG2 cells

Keywords: Cucurbitacin; Chromatographic hydrophobicity index; CHI; HepG2; IC50; Cytotoxicity; Structure-activity relationship; SAR; log P; C log P; RP-HPLC;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

The use of flow cytometric methods in acute and long-term in vitro testing

Keywords: AAP; acetaminophen; CFSE; carboxyfluoresceindiacetate N-succinimidyl ester; 2,4-D; 2,4-dichlorophenoxy acetic acid; FCS; fetal calf serum; IC50; mean effective concentration; INH; isoniazid; PBS; phosphate buffered saline; PI; propidium iodide; RT; room t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

A modified, economic, sensitive method for measuring total antioxidant capacities of human plasma and natural compounds using Indian saffron (Crocus sativus)

Keywords: AAPH; 2.2′-azobis (2-amidinopropane) dihydrochloride; ABTS; 2,2′-azobis-3-ethylbenzthiazoline-6-sulfonic acid; CVD; cardiovascular diseases; DPPH; 1,1′-diphenyl-2-picrylhydrazyl; FRAP; Ferric reducing antioxidant power; IC50; Concentration which giv

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Low tumor cell density environment yields survival advantage of tumor cells exposed to MTX in vitro

Keywords: DHFR; dihydrofolate reductase gene; FBS; fetal bovine serum; IC50; 50% inhibitory drug concentration; LCD; low cell density; MTX; methotrexate; NBMPR; nitrobenzyl-mercaptopurine ribonucleoside; DP; dipyridamole; SCD; standard cell density; Drug resistance

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Specific dose-dependent damage of Lieberkühn crypts promoted by large doses of type 2 ribosome-inactivating protein nigrin b intravenous injection to mice

Keywords: TUNEL; terminal deoxyribonucleotidyl transferase-mediated dUTP-nick-end labeling; IC50; inhibitory concentration 50%; Nigrin b; Ricin; Ribosome-inactivating protein; Apoptosis; Small intestine; Stem cells;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Antioxidant activity of Crataegus aronia aqueous extract used in traditional Arab medicine in Israel

Keywords: AAPH; 2,2′-azobis(2-amidino-propan) dihydrochloride; ANOVA; one-way analysis of variance; BHA; butylated hydroxyanisole; DMEM; Dulbecco's modified Eagle's medium; DTNB; 5,5′-dithio-bis-2-nitrobenzoic acid; ELISA; enzyme-linked immunosorbent assay; GSH

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

(5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide analog mediates immunosuppressive effects in vitro and in vivo

Keywords: LLDT-8; (5R)-5-hydroxytriptolide; ConA; concanavalin A; LPS; lipopolysaccharide; Sac; Staphylococcus aureus Cowan strain I; MLR; mixed lymphocyte reaction; DNFB; 2,4-dinitrofluorobenzene; DTH; delayed-type hypersensitivity; SRBC; sheep red blood cell; QHS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles

Keywords: C-26; colon adenocarcinoma 26; CDDP; cis-dichlorodiammineplatinum(II); DACH; diaminocyclohexane; DACHPt; dichloro(1,2-diaminocyclohexane)platinum(II); DMF; N,N-Dimethylformamide; EPR; enhanced permeability and retention; FDA; Food and Drug Administration;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Plasmodium falciparum: Stage specific effects of a selective inhibitor of lactate dehydrogenase

Keywords: Protozoa; Plasmodium falciparum; Lactate dehydrogenase; Inhibition; Intraerythrocytic cycle; Stage specificity; PfLDH; Plasmodium falciparum lactate dehydrogenase; hLDH; human lactate dehydrogenase; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; ATP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

A review of the effects of the oral direct thrombin inhibitor ximelagatran on coagulation assays

Keywords: ACT; activated clotting time; APTT; activated partial thromboplastin time; DTI; direct thrombin inhibitor; ECT; ecarin clotting time; FV; factor V; IC50; plasma concentration of anticoagulant agent that doubles the clotting time compared with anticoagulan

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Cytotoxicity determination without photochemical artifacts

Keywords: Chemosensitivity testing; KB cells; NCI-H69 cells; H69AR cells; IC50; Riboflavin; CI; confidence interval; CIS; cis-platin; DOX; doxorubicin; ETO; etoposide; GEM; gemcitabine; HEPES; N-(2-hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid); IC20, IC50, I

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular characterisation of two human cancer cell lines selected in vitro for their chemotherapeutic drug resistance to ET-743

Keywords: DDH; dihydrodiol dehydrogenase gene; cDDP; cis-diamminedichloroplatinum; GLUL; glutamine synthase; GST; glutathione S-transferase; NER; nucleotide excision repair; XPG; Xeroderma pigmentosum group G; DMSO; dimethylsulphoxide; DX; doxorubicin; LC-MS/MS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Effect of pesticides on estrogen receptor transactivation in vitro: A comparison of stable transfected MVLN and transient transfected MCF-7 cells

Keywords: β-gal; β-galactosidase; E2; 17β-estradiol; EC100; effect concentration giving 100% (maximum) response; EC50; effect concentration giving 40% of maximum response; ER; estrogen receptor; IC50; 50% inhibitory concentration; LOEC; lowest observed effect co

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Kinetics of charge translocation in the passive downhill uptake mode of the Na+/H+ antiporter NhaA of Escherichia coli

Keywords: DDM; dodecyl-β-d-maltoside; mAb; monoclonal antibody; SSM; solid supported membrane; His-NhaA; His-tagged NhaA Na+/H+ exchanger; IC50; half maximum inhibitory concentration; RSO; right side out; CholineCl; C5H14NOCl; LPR; lipid to protein ratio; NhaA; So

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular modification of a recombinant, bivalent anti-human CD3 immunotoxin (Bic3) results in reduced in vivo toxicity in mice

Keywords: ARL; aggregation reducing linker; AML; acute myeloid leukemia; Bic3; DT390 fused to two anti-CD3 sFv with portion of immunoglobulin constant region; CD3ɛ; CD3 epsilon; CH domain; constant-heavy chain domain; DMEM; Dulbecco's minimal essential media; DT;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Corticotropin-Releasing Hormone Receptor 1 Antagonist Blocks Brain-Gut Activation Induced by Colonic Distention in Rats

Keywords: CRH; corticotropin-releasing hormone; CRHR; CRH receptor; EPM; elevated plus maze; HPLC; high-performance liquid chromatography; IBS; irritable bowel syndrome; IC50; median inhibitory concentration; LC; locus ceruleus; PVN; paraventricular nucleus;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

In vitro cytotoxicity of selected chemicals commonly produced during fire combustion using human cell lines

Keywords: In vitro cytotoxicity; Fire combustion products; MTS assay; Human cell lines; A549; human alveolar epithelial lung cells; ANOVA; analysis of variance; DMEM/F12; Dulbecco's modified essential medium/Ham's 12 nutrient mixture; HCl; hydrogen chloride; HF

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Heavy metals modulate the activity of the purinergic P2X4 receptor

Keywords: Ag+; silver; ATP; adenosine 5′-triphosphate; Cd2+; cadmium; Co2+; cobalt; Cu2+; copper cys, cysteine; EC50; median effective concentration; Ga3+; gallium; Hg2+; mercury; his; histidine; IC50; median inhibitory concentration; Imax; maximal current; Mn2+;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Capsaicin differentially modulates voltage-activated calcium channel currents in dorsal root ganglion neurones of rats

Keywords: Sensory systems; Pain modulation: pharmacology; [Ca2+]i; intracellular calcium concentration; Calciseptine; specific L-type calcium channel blocker; Caps; Capsaicin (8-methyl-N-vanillyl-6-nonenamide); DRG; dorsal root ganglion; EGTA; ethylene glycol-bis(2

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Mapping of the Hepatitis B Virus Attachment Site by Use of Infection-Inhibiting preS1 Lipopeptides and Tupaia Hepatocytes

Keywords: AA; amino acid; HBeAg; hepatitis B e antigen; HBs; hepatitis B surface; HBsAg; hepatitis B surface antigen; IC50; 50% inhibitory concentration; LDH; lactate dehydrogenase; MAb; monoclonal antibody; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Multiple interaction sites of galnon trigger its biological effects

Keywords: AR; adrenoreceptor; AVP; [Arg8]vasopressin; CHO; Chinese hamster ovary; D1(2)R; dopamine receptors, type 1 (2); DMSO; dimethylsulfoxide; GalR; galanin receptor; GPCR; G-protein coupled receptors; HKR; Hepes-Krebs-Ringer solution; HPLC; high performanc

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Transport of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide by human intestinal Caco-2 cells

Keywords: ACSRC; Auckland Cancer Society Research Centre; AP; apical; BL; basolateral; CYP; cytochrome P450; DMSO; dimethyl sulphoxide; DMXAA; 5,6-dimethylxanthenone-4-acetic acid; DMXAA-G; DMXAA acyl glucuronide; HBSS; Hanks' balanced salt solution; HEPES; N-[2-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells

Keywords: 5-Aza-C; 5-azacytidine; 5-Aza-dC; 5-aza-2′-deoxycytidine; Zeb; zebularine; Zeb-MP; zebularine-5′-monophosphate; Zeb-DP; zebularine-5′-diphosphate; Zeb-TP; zebularine-5′-triphosphate; Zeb-DP-EA; zebularine-5′-diphosphoethanolamine; Zeb-DP-Chol; z

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Extracts and molecules from medicinal plants against herpes simplex viruses

Keywords: ACV; acyclovir; ACV-R; acyclovir-resistant; ACV-S; acyclovir susceptible; ADMET; absorption distribution metabolism, excretion and toxicity; AIDS; acquired immune-deficiency syndrome; CC50; median cytotoxic concentration; CPE; cytopathic effect; EC50; med

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

N-methyl-d-aspartate receptors and large conductance calcium-sensitive potassium channels inhibit the release of opioid peptides that induce μ-opioid receptor internalization in the rat spinal cord

Keywords: dorsal horn; dynorphin; enkephalin; internalization; mu-opioid receptor; opioid; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; AP-5; dl-2-amino-5-phosphonopentanoic acid; BK(Ca2+); large conductance Ca2+-sensitive K+ channels; CCK; ch

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Tonic excitation and inhibition of neurons: ambient transmitter sources and computational consequences

Keywords: Glutamate; GABA; Uptake; Release; Tonic; Ambient; Extracellular; EC50; Concentration producing a half-maximal response; IC50; Concentration producing a half-maximal inhibition;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Contrasting the effects of nifedipine on subtypes of endogenous and recombinant T-type Ca2+ channels

Keywords: Amax; maximal percentage of inhibition; DMSO; dimethyl sulfoxide; HVA; high voltage-activated; IC50; half-inhibitory concentration; Iα1G; current through heterologously expressed α1G (Cav3.1) subunit of low voltage-activated calcium channel; Iα1H; curr

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

GABAA receptor facilitation of neurokinin release from primary afferent terminals in the rat spinal cord

Keywords: C-fiber; dorsal horn; GABA; internalization; neurokinin 1 receptor; substance P; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; CGP-55845; (2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl) phosphinic acid;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

Neuroprotective effects of inhibiting N-methyl-d-aspartate receptors, P2X receptors and the mitogen-activated protein kinase cascade: A quantitative analysis in organotypical hippocampal slice cultures subjected to oxygen and glucose deprivation

Keywords: propidium iodide; PD98059; MK-801; suramin; ischemia; stroke; BME; basal medium Eagle's solution; DMSO; dimethyl sulfoxide; ECF; Enhanced Chemi-Fluorescence; ERK; extracellular signal-regulated kinase; FD; fascia dentata; HBSS; Hanks' balanced salt so

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه

Thiopurines in inflammatory bowel disease: pharmacogenetics, therapeutic drug monitoring and clinical recommendations

Keywords: AO; aldehyde oxidase; AZA; azathioprine; CD; Crohn's disease; DNA; deoxynucleic acid; FDA; Food and Drug Administration; GMPS; guanosine monophosphate synthetase; HPRT; hypoxanthine phosphoribosyl transferase; IBD; inflammatory bowel disease; IBDQ; Inflam

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه

Peptide inhibitors of protein kinases-discovery, characterisation and use

Keywords: AKAP; A-Kinase Anchoring Protein; EGF-R; Epidermal Growth Factor-Receptor; GSK; Glycogen Synthase Kinase; IC50; concentration of compound to achieve 50% inhibition; JIP; JNK Interacting Protein; JNK; c-Jun N-terminal Kinase; Ki; inhibition constant; MLCK;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2005 سفارش ترجمه