Keywords: گیرنده فاکتور 1 رشد انسولین; Atherosclerosis; Cardiovascular diseases; Cell cycle; Proliferation; Pulmonary hypertension; Restenosis; Signaling pathway; Vascular smooth muscle cells; ACE; angiotensin converting enzyme; aFGF; acidic FGF; Ang II; angiotensin II; AP-1; activating protei
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Keywords: گیرنده فاکتور 1 رشد انسولین; EGFR; Epidermal growth factor receptor; TP53; Tumor protein p53; KRAS; Kirsten rat carcoma viral oncogene; ALK; Anaplastic lymphoma kinase; RTK; Protein receptor tyrosine kinase; TKI; Tyrosine kinase inhibitor; PI3K; Phosphatidylinositol 3-kinase; NSCLC;
Keywords: گیرنده فاکتور 1 رشد انسولین; Intervertebral disc homeostasis; Insulin-like growth factor-1; Insulin-like growth factor binding proteins; Insulin-like growth factor-1 receptor; Disc cells metabolism;
Keywords: گیرنده فاکتور 1 رشد انسولین; HOMA-IR; Diabetes Drug; Cancer Development; Tumorigenesis; AE; adverse event; AMP; adenosine monophosphate; AMPK; adenosine monophosphate-activated protein kinase; BE; Barrett's esophagus; BMI; body mass index; EAC; esophageal adenocarcinoma; EGD; eso
Keywords: گیرنده فاکتور 1 رشد انسولین; AKAP; A-Kinase Anchoring Protein; ALL; acute lymphoblastic leukemia; A.S.; activation segment; CDK; cyclin-dependent kinase; CML; chronic myelogenous leukemia; C-spine; catalytic spine; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth facto
Keywords: گیرنده فاکتور 1 رشد انسولین; HER2; human epidermal growth factor receptor 2; HER3; human epidermal growth factor receptor 3; HRG; heregulin; IGF-1R; insulin-like growth factor-1 receptor; IGF-1; insulin-like growth factor-1; pAKT; phosphorylated AKT; dsIgG; dual-specific IgG; Immunog
Keywords: گیرنده فاکتور 1 رشد انسولین; EGFR; epidermal growth factor receptor; NSCLC; non-small cell lung cancer; TKI; tyrosine kinase inhibitor; WT; wild type; KRAS; Kirsten RNA associated rat sarcoma 2 virus gene; PTEN; phosphatase and tensin homolog; HGF; hepatocyte growth factor; IGF1R; in
Keywords: گیرنده فاکتور 1 رشد انسولین; Equine; Laminitis; Insulin; Insulin-like growth factor-1 receptor;
Keywords: گیرنده فاکتور 1 رشد انسولین; IGFs; insulin-like growth factors; SHBG; sex hormone binding globulin; BMI; body mass index; IGFBPs; IGF binding proteins; IGF-1R; insulin-like growth factor-1 receptor; CLS; crown-like structure; NFκB; nuclear factor kappa-B; STAT3; signal transducer an
Keywords: گیرنده فاکتور 1 رشد انسولین; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ERK; extracellular-signal-regulated kinases; ESC; embryonic stem cells; FACS; fluorescence-activated cell sorter; FGF2; fibroblast growth factor-2 (basic); IGF1; insulin-like growth fac
Low-expressional IGF1 mediated methimazole-induced liver developmental toxicity in fetal mice
Keywords: گیرنده فاکتور 1 رشد انسولین; IGF-1R; insulin-like growth factor-1 receptor; Akt2; serine-threonine protein kinase 2; HMGCR; HMG CoA reductase; FASN; fatty acid synthase; PEPCK; phosphoenolpyruvate carboxykinase; PCNA; proliferating cell Nuclear antigen; HNF4α; hepatocyte nuclear fac
The beneficial effects of Zn on Akt-mediated insulin and cell survival signaling pathways in diabetes
Keywords: گیرنده فاکتور 1 رشد انسولین; Akt2-KO; Akt2 gene deletion; CHO; Chinese hamster ovary; DM; diabetes mellitus; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; GLUT4; glucose transporter type-4; GS; glycogen synthase; GSK-3; glycogen synt
Necroptosis in 3-chloro-1, 2-propanediol (3-MCPD)-dipalmitate-induced acute kidney injury in vivo and its repression by miR-223-3p
Keywords: گیرنده فاکتور 1 رشد انسولین; 3-MCPD; 3-chloro-1,2-propanediol; 3â²UTR; 3â² un-translated region; AKI; acute kidney injury; BMD10; Benchmark doses; BMDL10; BMD Lower Confidence Limit; BW; body weight; CXCl; chemokine (C-X-C motif) ligand; DE; differentially expressed; DR6; death rec
MicroRNAs link chronic inflammation in childhood to growth impairment and insulin-resistance
Keywords: گیرنده فاکتور 1 رشد انسولین; ALS; acid-labile subunit; APC; antigen-presenting cell; CXCL2; chemokine (C-X-C motif) ligand 2; ESR; erythrocyte sedimentation rate; FGFR1; fibroblast growth factor receptor 1; FOXO1; Forkhed box O1; FOXP3; forkhead box P3; GH; growth hormone; GHR; growt
The interaction of IGF-1/IGF-1R and hydrogen sulfide on the proliferation of mouse primary vascular smooth muscle cells
Keywords: گیرنده فاکتور 1 رشد انسولین; BrdU; bromodeoxyuridine; CBS; cystathionine-beta-synthase; CRISPR; clustered regularly interspaced short palindromic repeats; CSE; cystathionine-gamma-lyase; DMEM; dulbecco's modified eagle's medium; ERK; extracellular regulated protein kinase; FBS; f
Exosomes and regenerative medicine: state of the art and perspectives
Keywords: گیرنده فاکتور 1 رشد انسولین; adMSCs; adipose-derived MSCs; AIS; acute ischemic stroke; AKI; acute kidney injury; AMI; acute myocardial infarction; BMP-7; bone morphogenetic protein 7; CCl4; carbon tetrachloride; CDCs; cardiosphere-derived cells; CM; conditioned medium; CPCs; cardiac
Optimal salinity for rearing Chinese black sleeper (Bostrychus sinensis) fry
Keywords: گیرنده فاکتور 1 رشد انسولین; Bostrychus sinensis; Salinity; Growth; Insulin-like growth factor-1 receptor; Na+-K+-ATPase activity;
Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways
Keywords: گیرنده فاکتور 1 رشد انسولین; Icariin; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Phosphatidylinositol 3-kinase; Mitogen-activated protein kinase kinase; Dopamine; Parkinson's disease; DA; dopamine; IGF-1R; insulin-like growth factor-1 receptor; IRS-1; insulin receptor substrate-1;
The impact of the IGF-1 system of cancer cells on radiation response - An in vitro study
Keywords: گیرنده فاکتور 1 رشد انسولین; IGF-1R; insulin-like growth factor 1 receptor; SF; surviving fractions; IGF-1R/KR; kinase-deficient IGF-1R; Caco-2-KR4; IGF-1R/KR clone number 4; IRS-1; insulin receptor substrate 1; HRR; homologous recombination repair; NHEJ; non-homologous end joining;
The activation of the G protein-coupled estrogen receptor (GPER) inhibits the proliferation of mouse melanoma K1735-M2 cells
Keywords: گیرنده فاکتور 1 رشد انسولین; G protein-coupled estrogen receptor (GPER); Melanoma; Antiestrogens; Proliferation; BCA; bicinchoninic acid; BrdU; 5-bromo-2â²-deoxyuridine; CYP; cytochrome P450; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; EC
Roles for RACK1 in cancer cell migration and invasion
Keywords: گیرنده فاکتور 1 رشد انسولین; EMT; Epithelial to mesenchymal transition; FAK; Focal adhesion kinase; MMPs; Matrix metalloproteases; IGF-I; Insulin-like Growth Factor-1; IGF-IR; Insulin-like Growth Factor-1 Receptor; PP2A; Protein Phosphatase 2A; PI3K; Phosphoinositide 3-kinase; PI(3,4
S-nitrosylation of the IGF-1 receptor disrupts the cell proliferative action of IGF-1
Keywords: گیرنده فاکتور 1 رشد انسولین; Insulin-like growth factor; Nitric oxide; S-Nitrosylation; Signal transduction; ERK; extracellular signal-regulated protein kinase; IGF-1; insulin-like growth factor-1; IGF-1R; insulin-like growth factor-1 receptor; IRS; insulin receptor substrate; MAPK;
The role of miRNA-223 in cancer: Function, diagnosis and therapy
Keywords: گیرنده فاکتور 1 رشد انسولین; miRNAs; MicroRNAs; UTR; The 3â² untranslated region; oncomiRs; Oncogenic miRNAs; miR-223; miRNA-223; T-ALL; T-cell acute lymphoblastic leukemia; AML; Acute myeloid leukemia; NSCLC; Nonsmall cell lung cancer; C/EBP; CCAAT-enhancer-binding protein; NFI-A;
Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor-Rac1 Activation to Inhibit Keratinocyte Motility
Keywords: گیرنده فاکتور 1 رشد انسولین; AS; antisense oligonucleotide; GCS; glucosylceramide synthase; GCSI; glucosylceramide synthase inhibitor; GM3S; ganglioside GM3 synthase; IGF-1; insulin-like growth factor-1; IGF1R; insulin-like growth factor-1 receptor; IR; insulin receptor; M2D3; GM2/GD
Anaplastic lymphoma kinase (ALK) inhibitors in the treatment of ALK-driven lung cancers
Keywords: گیرنده فاکتور 1 رشد انسولین; Alectinib: (PubMED CID: 49806720); Brigatinib: (PubMED CID: 68165256); Ceritinib: (PubMED CID: 57379345); Crizotinib (PubMED CID: 11626560); Entrectinib: (PubMED CID: 25141092); Lorlatinib: (PubMed CID: 71731823); ALK+-NSCLC; ALK-positive non-small cell l
A Randomized, Placebo-Controlled, Phase 1b/2 Study of Rilotumumab or Ganitumab in Combination With Platinum-Based Chemotherapy as First-Line Treatment for Extensive-Stage Small-Cell Lung Cancer
Keywords: گیرنده فاکتور 1 رشد انسولین; Clinical trial; Hepatocyte growth factor; Insulin-like growth factor-1 receptor; MET; Small-cell lung carcinoma;
Involvement of IGF-1 receptor signaling pathway in the neuroprotective effects of Icaritin against MPP+-induced toxicity in MES23.5 cells
Keywords: گیرنده فاکتور 1 رشد انسولین; Icaritin; 1-Methyl-4-phenylpyridinium ion; Insulin-like growth factor-1 receptor; Akt; ERK1/2; MES23.5 cells
MicroRNAs: New regulators of IL-22
Keywords: گیرنده فاکتور 1 رشد انسولین; IL-22; interleukin-22; Th22; T helper 22 cell; Th1; T helper 1 cell; Th17; T helper 17 cell; NK22; natural killer 22; NKT; natural killer T cell; ILCs; innate lymphoid cells; RORγt; retinoid orphan receptor γt; STAT3; signal transducer and activator of
Insulin-like growth factor-1 receptor regulates repair of ultraviolet B-induced DNA damage in human keratinocytes in vivo
Keywords: گیرنده فاکتور 1 رشد انسولین; IGF-1R; NER; Keratinocyte; UVB; Xenograft; IGF-1; insulin-like growth factor-1; IGF-1R; insulin-like growth factor-1 receptor; UVB; ultraviolet B; NMSC; non-melanoma skin cancer; SCC; squamous cell carcinoma; NER; nucleotide excision repair; TD; thymine d
Increased IGFBP-1 phosphorylation in response to leucine deprivation is mediated by CK2 and PKC
Keywords: گیرنده فاکتور 1 رشد انسولین; Amino acid restriction; Fetal growth; HepG2 cells; Insulin-like growth factor binding protein; Insulin-like growth Factor-1 receptor; Protein kinases; Phosphorylation sites; Mass spectrometry
MicroRNAs associated with the pathogenesis of multiple sclerosis
Keywords: گیرنده فاکتور 1 رشد انسولین; BBB; blood-brain barrier; BMI1; B lymphoma Mo-MLV insertion region 1 homolog; CAPS-3; caspase-3; CEBPB; CCAAT/enhancer-binding protein beta; CNS; central nervous system; EAE; experimental autoimmune encephalomyelitis; GA; Glatiramer acetate; HIF-1; hypo
The viral G protein-coupled receptor ORF74 unmasks phospholipase C signaling of the receptor tyrosine kinase IGF-1R
Keywords: گیرنده فاکتور 1 رشد انسولین; ORF74; Insulin-like growth factor-1 receptor; Crosstalk; Herpesvirus; G protein-coupled receptor; Receptor tyrosine kinase;
Relative expression of the p75 neurotrophin receptor, tyrosine receptor kinase A, and insulin receptor in SH-SY5Y neuroblastoma cells and hippocampi from Alzheimer's disease patients
Keywords: گیرنده فاکتور 1 رشد انسولین; Alzheimer disease; Insulin-like growth factor-1 receptor; Insulin receptor; PSD95; p75 neurotrophin receptor; tyrosine receptor kinase-A; AD; Alzheimer's disease; FBS; fetal bovine serum; HMW; high molecular weight; IGF-1R; insulin-like growth factor-1
Inhibition of the insulin-like growth factor 1 receptor by CHM-1 blocks proliferation of glioblastoma multiforme cells
Keywords: گیرنده فاکتور 1 رشد انسولین; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth factor receptor; GBM; glioblastoma multiforme; IGF-1R; insulin-like growth factor-1 receptor; IR; insulin receptor; PDGFR; platelet-derived growth factor receptor; PI3K; phosphatidylinositol
Autophagy in zebrafish
Keywords: گیرنده فاکتور 1 رشد انسولین; 3MA; 3-methyladenin; AC; adenylyl cyclase; AMPK; adenosine monophosphate-dependent kinase; Atg; autophagy related gene; BafA1; Bafilomycin A1; CMV; cytomegalovirus; CQ; chloroquine; dpa; days post amputation; dpf; days post fertilization; ERK; extracellul
Metformin inhibits age-related centrosome amplification in Drosophila midgut stem cells through AKT/TOR pathway
Keywords: گیرنده فاکتور 1 رشد انسولین; 4E-BP; eukaryotic translation initiation factor 4E-binding protein; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; AMPK; 5â² AMP-activated protein kinase; EBs; enteroblasts; ECs; enterocytes; EEs; enteroendocrine cells; EGFR; epidermal growth factor receptor; IGF1
β-Arrestin-1 protects against endoplasmic reticulum stress/p53-upregulated modulator of apoptosis-mediated apoptosis via repressing p-p65/inducible nitric oxide synthase in portal hypertensive gastropathy
Keywords: گیرنده فاکتور 1 رشد انسولین; PHG; portal hypertensive gastropathy; PVL; partial portal vein ligation; SO; sham operation; PUMA; p53-upregulated modulator of apoptosis; ER; endoplasmic reticulum; GPCR; G-protein-coupled receptors; iNOS; inducible nitric oxide synthase; NF-κB; nuclear
microRNA-7: A tumor suppressor miRNA with therapeutic potential
Keywords: گیرنده فاکتور 1 رشد انسولین; ACK1; activated CDC42 kinase 1; Akt; V-Akt murine thymoma viral oncogene homolog; BCL-2; B-cell CLL/lymphoma 2; CCNE1; cyclin E1; ciRS-7; circular RNA sponge 7; c-Myc; V-Myc avian myelocytomatosis viral oncogene homolog; EGFR; epidermal growth factor rece
mRNA Expression of IGF-1 and IGF-1R in Patients with Colorectal Adenocarcinoma and Type 2 Diabetes
Keywords: گیرنده فاکتور 1 رشد انسولین; Insulin-like growth factor-1; Insulin-like growth factor-1 receptor; Messenger RNA; Colorectal adenocarcinoma; Type 2 diabetes
Picropodophyllin inhibits tumor growth of human nasopharyngeal carcinoma in a mouse model
Keywords: گیرنده فاکتور 1 رشد انسولین; Nasopharyngeal carcinoma; Insulin-like growth factor-1 receptor; Picropodophyllin; Akt; Nude mouse;
Clinical significance of proliferation, apoptosis and senescence of nasopharyngeal cells by the simultaneously blocking EGF, IGF-1 receptors and Bcl-xl genes
Keywords: گیرنده فاکتور 1 رشد انسولین; Bcl-xl; Short hairpin RNA; Nasopharyngeal cancer; Epidermal growth factor receptor; Insulin-like growth factor-1 receptor; Senescence;
Picropodophyllin inhibits epithelial ovarian cancer cells in vitro and in vivo
Keywords: گیرنده فاکتور 1 رشد انسولین; Picropodophyllin; Cisplatin; Ovarian carcinoma; Insulin-like growth factor-1 receptor;
Impact of targeting insulin-like growth factor signaling in head and neck cancers
Keywords: گیرنده فاکتور 1 رشد انسولین; IGF; insulin-like growth factor; IGF-1-R; insulin-like growth factor-1 receptor; IRS; insulin receptor substrate; IGFBP; insulin-like growth factor binding protein; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; MAPK; mitogen-activa
Insulin-like growth factor-1 receptor protein expression and gene copy number alterations in non–small cell lung carcinomas
Keywords: گیرنده فاکتور 1 رشد انسولین; Insulin-like growth factor-1 receptor; Gene copy number; Non–small cell lung carcinoma; Bright-field in situ hybridization
Downregulation of miR-223 and miR-153 mediates mechanical stretch-stimulated proliferation of venous smooth muscle cells via activation of the insulin-like growth factor-1 receptor
Keywords: گیرنده فاکتور 1 رشد انسولین; Vascular smooth muscle cells; VSMCs; Insulin-like growth factor-1 receptor; IGF-1R; MiR-223; MiR-153; PI3K-AKT pathway;
Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells
Keywords: گیرنده فاکتور 1 رشد انسولین; SFKs; Src family tyrosine kinases; EGF-R; epidermal growth factor receptor; PDGF-R; platelet-derived growth factor receptor; IGF-1R; insulin-like growth factor-1 receptor; VEGF-R; vascular endothelial growth factor receptor; FGF-R; fibroblast growth facto
Indole-3-Carbinol disrupts Estrogen Receptor-alpha dependent expression of Insulin-like Growth Factor-1 Receptor and Insulin Receptor Substrate-1 and proliferation of human breast cancer cells
Keywords: گیرنده فاکتور 1 رشد انسولین; I3C, Indole-3-carbinol; ERα, Estrogen Receptor-alpha; IRS1, Insulin Receptor Substrate-1; IGF1R, Insulin-like Growth Factor-1 ReceptorIndole-3-carbinol; Estrogen receptor-alpha; Insulin Receptor Substrate-1; Insulin-like Growth Factor-1 Receptor; Hormone
Peripheral regulation of the growth hormone-insulin-like growth factor system in fish and other vertebrates
Keywords: گیرنده فاکتور 1 رشد انسولین; cAMP; cyclic adenosine monophosphate; ERK; extracellular signal-regulated kinase; E2; 17β-estradiol; GH; growth hormone; GHR; growth hormone receptor; GHBP; growth hormone binding protein; HNF; hepatocyte nuclear factor; IGF; insulin-like growth factor;
Discovery of novel imidazo[1,2-a]pyridines as inhibitors of the insulin-like growth factor-1 receptor tyrosine kinase
Keywords: گیرنده فاکتور 1 رشد انسولین; IGF1-R; Insulin-like growth factor-1 receptor; Tyrosine kinase inhibitor
Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors
Keywords: گیرنده فاکتور 1 رشد انسولین; Insulin-like growth factor-1 receptor; IGF-1R; Kinase; Pyrimidine; Calu-6 xenograft; X-ray cocrystal structure