دانلود مقالات ISI درباره دامنه درون سلولی + ترجمه فارسی

مبنای ساختاری انتقال سیگنال از طریق غشای فرابنفش گیرنده هورمون رشد انسانی

Structural basis of the signal transduction via transmembrane domain of the human growth hormone receptor

Keywords: دامنه درون سلولی; GHR; growth hormone receptor; GHRtm; recombinant fragment GHR254-294; JAK2; Janus kinase 2; RTK; receptor tyrosine kinase; TMD; transmembrane domain; ECD; extracellular domain; ICD; intracellular domain; JM; juxtamembrane; ecJM; extracellular juxtamembr

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

انتقال و سازگاری متقابل و تعاملی که عامل عملکرد پروتئین گیرنده غشایی است

Conformational transitions and interactions underlying the function of membrane embedded receptor protein kinases

Keywords: دامنه درون سلولی; RTK; receptor tyrosine kinase; TKL; tyrosine kinase-like receptor; GPI-AP; glycosylphosphatidylinositol-anchored protein; SH2; Scr homology 2 domain; TMD; transmembrane domain; ECD; extracellular domain or ectodomain; ICD; intracellular domain; JM; juxtam

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

تعامل هلیکس-هلیکس در دامنه های غشایی پروتئین های بیتوپیک: ویژگی و نقش محیط لیپید

Helix-helix interactions in membrane domains of bitopic proteins: Specificity and role of lipid environment

Keywords: دامنه درون سلولی; BP; bitopic protein; RTK; receptor tyrosine kinase; TMD; transmembrane domain; JM; juxtamembrane; ECD; extracellular domain; ICD; intracellular domain; NMR; nuclear magnetic resonance; MD; molecular dynamics; LID; “ligand-induced dimerization” mechani

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

فعال سازی سیگنالینگ تبدیل بتا 1 در فیبروبلاست های مرتبط با سرطان معده باعث افزایش تحرک آنها از طریق بیان رمبوید 5 همولوگ 2 و توانایی ایجاد انگیزه سلول های سرطانی معده می شود.

Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells

Keywords: دامنه درون سلولی; Tumor Stroma; Inflammation; Stomach Cancer; Tumor Cells; α-SMA; alpha-smooth muscle actin; CAFs; cancer-associated fibroblasts; CM; conditioned medium; DGC; diffuse-type gastric cancer; ECM; extracellular matrix; EMT; epithelial-to-mesenchymal transition

دانلود رایگان متن کامل مقاله ISI 79 صفحه سال انتشار : 2017 سفارش ترجمه

سیستم تحویل مواد مخدر هدف قرار دادن کارسینومیک پیشرفته سلولی: فعلی و آینده

Drug delivery system targeting advanced hepatocellular carcinoma: Current and future

Keywords: دامنه درون سلولی; HCC; hepatocellular carcinoma; DDS; drug delivery system; ECM; extracellular matrix; MVD; microvessel density; EPR; enhanced permeability and retention; ASGP-R; asialoglycoprotein receptor; GPC3; glypican 3; HS chain; heparin sulfate chain; GA; glycyrrhet

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2016 سفارش ترجمه

پاره شدن خارج سلولی از گیرنده نوروتروف پراکسیک در اثر پروتئین بقا در سلول های سرطان پستان

Extracellular cleavage of the p75 neurotrophin receptor is implicated in its pro-survival effect in breast cancer cells

Keywords: دامنه درون سلولی; FBS; fetal bovine serum; CTF; carboxyl-terminal fragment; ICD; intracellular domain; RIP; regulated intramembrane proteolysis; PS; presenilin; ADAM; a disintegrin and metalloprotease; TAPI; tumor necrosis factor-α protease inhibitor; TRAIL; TNF-related a

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

A modified clear-native polyacrylamide gel electrophoresis technique to investigate the oligomeric state of MBP-5-HT3A-intracellular domain chimeras

Keywords: دامنه درون سلولی; Clear-native PAGE; Multi-angle light scattering; Native gel electrophoresis; Protein oligomerization; Protein quaternary structures; Size exclusion chromatography; 5-HT3A; serotonin type 3A; 6-AHA; 6-aminohexanoic acid; BN-PAGE; blue-native polyacrylamide

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2019 سفارش ترجمه

Tyrosine kinase activity of EphA2 promotes its S897 phosphorylation and glioblastoma cell proliferation

Keywords: دامنه درون سلولی; EphA2; ERK; Cell proliferation; Glioblastoma; BrdU; bromodeoxyuridine; EGF; epidermal growth factor; ICD; intracellular domain; PI3K; phosphatidylinositol 3-kinase; PKA; protein kinase A; RSK; p90 ribosomal S6 kinase; RTK; receptor tyrosine kinase; S897;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB

Keywords: دامنه درون سلولی; ACh; acetylcholine; AChBP; acetylcholine-binding protein; ECD; extracellular domain; gAuIB; globular AuIB; ICD; intracellular domain; nAChR; nicotinic acetylcholine receptor; rAuIB; ribbon AuIB; SAR; structure-activity relationship; TMD; transmembrane dom

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

GLA supplementation regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DMBA induced mammary gland carcinoma

Keywords: دامنه درون سلولی; AA; arachidonic acid; AB; alveolar bud; AAA; aromatic amino acid; BCAA; branched chain amino acid; BSA; bovine serum albumin; BMRB; biological magnetic resonance databank; CEC; cuboidal epithelial cell; CPMG; carr-purcell-meiboom-gill; DMBA; 7, 12-d

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens

Keywords: دامنه درون سلولی; CKO; “conditional knock-out” allele; ICD; intracellular domain; NEXT; Notch extracellular truncation; PLE; presumptive lens ectoderm; AEL; anterior epithelial layer; E0.5; embryonic day 0.5; H&E; hematoxylin and eosin; OCT; optimal cutting temperature

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Objective, domain-specific HER2 measurement in uterine and ovarian serous carcinomas and its clinical significance

Keywords: دامنه درون سلولی; HER2; Intracellular domain; Extracellular domain; Serous carcinoma; Quantitative immunofluorescence; Targeted therapy;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of Wnt signaling by protocadherins

Keywords: دامنه درون سلولی; Pcdhs; protocadherins; EC; extracellular cadherin; PP1a; protein phosphatase 1a; WIRS; WRC interacting receptor sequence; FAK; focal adhesion kinase; PKC; protein kinase C; MMTV; mouse mammary tumor virus; Fzd; frizzleds; ICD; intracellular domain; Dvls;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

The roles of subcellularly located EGFR in autophagy

Keywords: دامنه درون سلولی; AMPK; AMP-activated protein kinase; ATG; autophagy-related; BCL2; B-cell lymphoma 2; BCL2L1; BCL2 like 1; BNIP3; BCL2/Adenovirus E1B-binding protein Nip3; CME; clathrin-mediated endocytosis; cytoSTAT3; cytoplasmic STAT3; Dsbs; double strand breaks; ECD; e

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Posttranslational proteolytic processing of Leda-1/Pianp involves cleavage by MMPs, ADAM10/17 and gamma-secretase

Keywords: دامنه درون سلولی; Gamma secretase; Proteolysis; ADAM; Immune regulation; Nervous system; Leda-1; liver endothelial differentiation-associated protein-1; Pianp; PILR alpha associated neural protein; PILR; paired immunoglobin-like type 2 receptor; AJAP-1; adherens-junction-a

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Simvastatin inhibits CD44 fragmentation in chondrocytes

Keywords: دامنه درون سلولی; Chondrocyte; Pericellular matrix; Statin; CD44; Lipid raft; ADAM10; HA; hyaluronan; OA; osteoarthritis; OSM; Oncostatin M; BAC; bovine articular chondrocytes; HAC; human articular chondrocytes; MT1-MMP; membrane type I metalloproteinase; ICD; intracellula

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The multifaceted roles of the invariant chain CD74 - More than just a chaperone

Keywords: دامنه درون سلولی; ICD; intracellular domain; MHCII; MHC class II; MIF; macrophage migration inhibitory factor; NTF; N-terminal fragment; SPPL2a; Signal peptide peptidase-like 2a; Invariant chain; Antigen presentation; Intramembrane proteolysis; Endosomal trafficking; Macro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2

Keywords: دامنه درون سلولی; GPR64; GPCR; G protein; Molecular pharmacology; Signal transduction; Peptide agonist; 7TM; seven-transmembrane spanning domain; CTF; C-terminal fragment; ECD; extracellular domain; eV; empty vector; DMEM; dulbecco minimum essential medium; ELISA; enzyme-l

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

The positive is inside the negative: HER2-negative tumors can express the HER2 intracellular domain and present a HER2-positive phenotype

Keywords: دامنه درون سلولی; HER 2; human epidermal growth factor receptor 2; FISH; fluorescent in situ hybridization; ECD; extracellular domain of HER2; ICD; intracellular domain of HER2; LC-MS; label-free nanoscale mass spectrometry; Human epithelial growth factor receptor 2 (HER

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells

Keywords: دامنه درون سلولی; CMA; chromosomal microarray analysis; ICD; intracellular domain; MHCII; MHC class II complex; NTF; N-terminal fragment; RIP; regulated intramembrane proteolysis; SPP; Signal peptide peptidase; SPPL; Signal-peptide-peptidase-like; Invariant chain; CD74; B

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells

Keywords: دامنه درون سلولی; Aβ; amyloid beta; AD; Alzheimer's disease; APP; amyloid precursor protein; BACE1; beta-site APP-cleaving enzyme 1; CuBD; copper binding domain; ICD; intracellular domain; PCa; prostate cancer; sAPPα; soluble APP alpha; sAPPβ; soluble APP beta; SDS-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Podoplanin is a substrate of presenilin-1/γ-secretase

Keywords: دامنه درون سلولی; PDPN; podoplanin; fl-PDPN; full-length PDPN; EC; extracellular; TM; transmembrane; CT; cytoplasmic; ERM; ezrin radixin moesin; CTF; C-terminal fragment; ICD; intracellular domain; PS; presenilin; MEF; mouse embryonic fibroblast; RIP; regulated intramembra

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Furin processing dictates ectodomain shedding of human FAT1 cadherin

Keywords: دامنه درون سلولی; ECD; extracellular domain; ICD; intracellular domain; ICN; intracellular fragment of Notch; LNR; LIN12/Notch repeats; LRP; LDL-receptor related protein; mAb; monoclonal antibody; NRR; negative regulatory region; PC; proprotein convertase; PCCD; primitive

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

A link between two tumorigenic proteins, CD44 and p21WAF1: CD44 increases phorbol ester-induced expression of p21WAF1 by stabilizing its mRNA and extending protein half-life

Keywords: دامنه درون سلولی; p21; CD44; RNA and protein stabilization; Ras/MAPK-pathway; ERM proteins; Agar colony formation; V; empty vector; ctrl; control; ICD; intracellular domain; CHX; cycloheximide; TPA; phorbol-12-myristate 13-acetate; ERM; ezrin, radixin, moesin; MEK; mitogen

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Vertebrate extracellular calcium-sensing receptor evolution: Selection in relation to life history and habitat

Keywords: دامنه درون سلولی; CaSR; calcium-sensing receptor; CRD; cysteine-rich domain; ECD; extracellular domain; GABABR; γ-aminobutyric acid type B receptor; GPCR; G protein-coupled receptor; ICD; intracellular domain; LRT; likelihood ratio test; MAP; mitogen-activated protein (ki

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Identification and characterization of an alternative splice variant of Mpl with a high affinity for TPO and its activation of ERK1/2 signaling

Keywords: دامنه درون سلولی; Mpl; the thrombopoietin receptor; TPO; thrombopoietin; Mpl-EC; the extracellular domain of thrombopoietin receptor; RT-PCR; reverse transcriptase-polymerase chain reaction; ERK1/2; extracellular signal-regulated protein kinases-1 and -2; T-ERK1/2; Total E

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Skeletal tissues in Mozambique tilapia (Oreochromis mossambicus) express the extracellular calcium-sensing receptor

Keywords: دامنه درون سلولی; CaSR; calcium-sensing receptor; EC50; effective concentration producing a 50% response; CRD; cysteine-rich domain; ECD; extracellular domain; GPCR; G protein-coupled receptor; ICD; intracellular domain; IHC; immunohistochemistry; RT-PCR; reverse transcrip

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Structural analysis of the intracellular domain of (pro)renin receptor fused to maltose-binding protein

Keywords: دامنه درون سلولی; Ang I; angiotensin I; ATP6ap2; adaptor protein type II vacuolar H+-ATPase; IC; intracellular domain; MBP; maltose binding protein from E. coli; MBP-PRR-IC; MBP fused with the intracellular domain of (pro)renin receptor; PLZF; transcriptional factor prom

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Among γ-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells

Keywords: دامنه درون سلولی; Notch; γ-Secretase; Intracellular domain; Neural stem cell;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Intermediate monomer-dimer equilibrium structure of native ICAM-1: Implication for enhanced cell adhesion

Keywords: دامنه درون سلولی; ICAM-1; intercellular adhesion molecule-1; Ig; immunoglobulin; LFA-1; lymphocyte function-associated antigen-1; GPI; glycosylphophatidylinositol; SDF-1α; stromal-derived factor-1α; FITC; fluorescein isothiocyanate; ICAM-1; Immunoglobulin superfamily; Di

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

The intracellular domain of amyloid precursor protein induces neuron-specific apoptosis

Keywords: دامنه درون سلولی; APP, amyloid precursor protein; AICD, the intracellular domain of APP; AD, Alzheimer's diseaseAmyloid precursor protein; Intracellular domain; Cell death; Apoptosis; Alzheimer's disease

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders

Keywords: دامنه درون سلولی; ADAM; a disintegrin and metalloprotease; ACDL; acidic dileucine; ADDL; amyloid-β derived diffusible ligands; APP; amyloid precursor protein; Aph; anterior pharynx defective phenotype; APLP; APP-like protein; AICD; APP intracellular domain; AD; Alzheimer'

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular cloning and expression analysis of pig CD81

Keywords: دامنه درون سلولی; CHO; Chinese hamster ovary; Con A; concanavalin A; HCV; hepatitis C virus; ID; intracellular domain; LEL; large extracellular loop; LPS; lipopolysaccharide; PHA; phytohaemagglutinin; RACE; rapid amplification of cDNA ends; SEL; small extracellular loop; T

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Photic injury promotes cleavage of p75NTR by TACE and nuclear trafficking of the p75 intracellular domain

Keywords: دامنه درون سلولی; p75 neurotrophin receptor; p75ICD; p75NTR; Intracellular domain; Tumor necrosis factor-α converting enzyme; Photic injury; Apoptosis; Photoreceptor cellsTNFR, Tumor necrosis factor receptor; p75NTR, p75 neurotrophin receptor; p75ECD, p75NTR extracellular

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Region-specific growth properties and trophic requirements of brain- and spinal cord-derived rat embryonic neural precursor cells

Keywords: دامنه درون سلولی; brain; differentiation; embryonic; neural progenitor cells; neural stem cells; spinal cord; bFGF or FGF-2; basic fibroblast growth factor; Br; brain; E; embryonic day; EGF; epidermal growth factor; EGF-R; epidermal growth factor receptor; FGFR; basic fibr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Lipoprotein-mediated lipid transport in insects: Analogy to the mammalian lipid carrier system and novel concepts for the functioning of LDL receptor family members

Keywords: دامنه درون سلولی; apoE; apolipoprotein E; apoLp-II/I; apolipophorin II/I; apoLp-I; apolipophorin I; apoLp-II; apolipophorin II; apoLp-III; apolipophorin III; CE; cholesteryl ester; CETP; cholesteryl ester transfer protein; CHO; Chinese hamster ovary; DAG; diacylglycerol; E

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2005 سفارش ترجمه