دانلود مقالات ISI درباره Irf3 + ترجمه فارسی

یک روش برای تشخیص عفونت ویروس در سلول های تک و زمان واقعی: به سوی یک آزمایش خنثی سازی فلورسانس خودکار

A method for the detection of virus infectivity in single cells and real time: Towards an automated fluorescence neutralization test

Keywords: IRF3; Interferon regulatory factor 3; GFP; green fluorescent protein; PRNT; plaque reduction neutralization test; VSV; vesicular stomatitis virus; PFU; plaque forming units; moi; multiplicity of infection; LV; lentiviral vector; ZIKV; Zika virus; TBEV; ti

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

نقش کاپرف سلول در بیماری های کبدی

The role of Kupffer cells in hepatic diseases

Keywords: APCs; antigen-presenting cells; DAMPs; danger-associated molecular patterns; DCs; Donor-derived dendritic cells; ET; endotoxin tolerance; FFA; free fatty acids; Gsdmd; gasdermin D; HDAC11; Histone deacetylase 11; HFD; high fat diet; HMGB1; high mobility g

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

بازنویسی: گیرنده های تلفیقی میکروگلالی و بیماری آلزایمر

Reprint of: Microglial toll-like receptors and Alzheimer's disease

Keywords: AD; Alzheimer's disease; TLRs; toll-like receptors; AβPP; amyloid-β protein precursor; NSAIDs; non-steroidal anti-inflammatory drugs; CNS; central nervous system; TNF-α; tumor necrosis factor-α; IL-1β; interleukin 1-β; IL-6; interleukin-6; NO; nit

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

هدفون سلول های مشت: کشف نقش درمان دارویی در بیماری های بی شماری

Targeting mast cells: Uncovering prolific therapeutic role in myriad diseases

Keywords: AP1; Activator protein 1; cAMP; Cyclic adenosine monophoshate; CXCR; Cytokine receptors; CRTH2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; DAMPs; Damage-associated molecular pattern; EtBr; Ethidium Bromide; IgE; Immunoglobulin E;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

نکروز برنامه ریزی شده در پاتوژنز میکروبی

Programmed necrosis in microbial pathogenesis

Keywords: necrosis; necroptosis; RIP1; RIP3; MCMV; vaccinia; reovirus; Mycobacterium; Salmonella; Yersinia; Coxsackie B virus; cell death; innate immunity; host defense; TNF; Listeria; Human adenovirus; influenza; EPEC; PKR; IRF3

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

ویژگی های منحصر به فرد گیرنده های جوجه مرغ

Unique features of chicken Toll-like receptors

Keywords: CD14; cluster of differentiation 14; dsRNA; double stranded ribonucleic acid; IFN; interferon; IL; interleukin; IRAK; interleukin-1 receptor-associated kinase; IRF3; interferon regulatory factor 3; LBP; lipopolysaccharide-binding protein; LPS; lipopolysac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Synthetic RNA derived from the foot-and-mouth disease virus genome elicits antiviral responses in bovine and porcine cells through IRF3 activation

Keywords: Foot-and-mouth disease virus; IRF3; Bovine immunity; Antiviral immunity; Non-coding RNA;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

MCPIP1 negatively regulate cellular antiviral innate immune responses through DUB and disruption of TRAF3-TBK1-IKKε complex

Keywords: MCPIP1; Antiviral innate immune; Interferon; IRF3; TRAF3-TBK1-IKKε complex;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Seneca Valley Virus 3Cpro abrogates the IRF3- and IRF7-mediated innate immune response by degrading IRF3 and IRF7

Keywords: Seneca Valley Virus; Innate immunity; 3C-like protease; IRF3; IRF7;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

AKT1 distinctively suppresses MyD88-depenedent and TRIF-dependent Toll-like receptor signaling in a kinase activity-independent manner

Keywords: TLR; Toll-like receptor; TRIF; Toll/IL-1R domain-containing adaptor inducing IFN-β; LPS; lipopolysaccharide; KD; kinase-dead; IRAK; IL-1R-associated kinase; ISG; interferon stimulated gene; PIP3; phosphatidylinositol (3,4,5) trisphosphate; PH; pleckstrin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

STING positively regulates human ORMDL3 expression through TBK1-IRF3-STAT6 complex mediation

Keywords: ORMDL3; orosomucoid 1-like protein 3; GWAS; genome-wide association studies; EBV; Epstein-Barrvvirus; HRV; human rhinovirus; RSV; respiratory syncytial virus; STING; Stimulator of interferon genes; TLR; Toll-like receptors; NF-κB; nuclear factor κB; IFN

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Porcine circovirus type 2 inhibits inter-β expression by targeting Karyopherin alpha-3 in PK-15 cells

Keywords: Porcine circovirus type 2; Interferon; IRF3; Karyopherin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular mechanism of LPS-induced TNF-α biosynthesis in polarized human macrophages

Keywords: TTP; tristetraprolin; TRIF; TIR-domain-containing adapter-inducing interferon-β; TRAM; TRIF-related adapter molecule; IRF3; interferon regulatory factor 3; IFNAR; interferon-α/β receptor; ActD; actinomycin D; TIRAP; TIR-domain-containing adapter protei

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Cirsimarin, a flavone glucoside from the aerial part of Cirsium japonicum var. ussuriense (Regel) Kitam. ex Ohwi, suppresses the JAK/STAT and IRF-3 signaling pathway in LPS-stimulated RAW 264.7 macrophages

Keywords: Macrophage; JAK/STAT; IRF3; p38 cirsimarin; Cirsium japonicum var. ussuriense (Regel) Kitam. ex Ohwi;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

In vitro models for deciphering the mechanisms underlying the sexual transmission of viruses at the mucosal level

Keywords: BSA; Bovin Serum Albumin; CCL5; Chemokine Ligand 5; CCR7; Chemokine Receptor Type 7; CD; Cluster of Differentiation; CMV; Cytomegalovirus; DC-SIGN; Dendritic Cell-Specific ICAM-Grabbing Non-integrin; DNA; Deoxyribonucleic Acid; EDTA; Ethylenediaminetetraa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

The mechanisms of Ag85A DNA vaccine activates RNA sensors through new signal transduction

Keywords: DC; dendrite cells; BMDCs; bone-marrow dendrite cells; APC; antigen presenting cell; PRR; pattern recognition receptor; PAMPs; pathogen-associated molecular patterns; RIG-I; retinoic acid-inducible gene I; Mda-5; melanoma differentiation associated gene-5

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway

Keywords: ALI; acute liver injury; AST; aspartate transaminase; CD14; cluster of differentiation 14; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; glutamate-cysteine ligase modifier subunit; GSH; reduced glutathione; HO-1; hemeoxygenase-1; iNOS; inducibl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Accessory proteins 8b and 8ab of severe acute respiratory syndrome coronavirus suppress the interferon signaling pathway by mediating ubiquitin-dependent rapid degradation of interferon regulatory factor 3

Keywords: IFN antagonist; IRF3; SARS-CoV; ORF8; Ubiquitin-dependent degradation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Rig-I is involved in inflammation through the IPS-1/TRAF6 pathway in astrocytes under chemical hypoxia

Keywords: RIG-I; retinoic acid-inducible gene I; IPS-1; interferon-β promoter stimulator-1; TRAF; TNF receptor-associated factor; PRRs; pattern recognition receptors; TLRs; toll-like receptors; NLRs; NOD-like receptors; RLRs; RIG-like receptors; MDA5; melanoma dif

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Tripartite motif-containing (TRIM) 21 negatively regulates intestinal mucosal inflammation through inhibiting TH1/TH17 cell differentiation in patients with inflammatory bowel diseases

Keywords: Tripartite motif-containing 21; inflammatory bowel disease; CD4+ T cells; mucosal inflammation; TH1; TH17; A-CD; Active Crohn disease; A-UC; Active ulcerative colitis; CD; Crohn disease; CDAI; Crohn's Disease Activity Index; HC; Healthy control subject; I

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease

Keywords: ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; AUC; Area under the curve; BW; body weight; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic-reticulum; FBS; fetal bovine serum; FFA; free fatty acid; GCK; glucokinase; p-GSK3β; pho

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression

Keywords: PPARγ; Peroxisome proliferator-activated receptor γ; ECM; extracellular matrix; TGF-β; transforming growth factor-β; PI3K; phosphoinositide 3-kinase; F-actin; filamentous-actin; TNF-α; tumor necrosis factor-α; IL; interleukin; FCS; fetal calf serum;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy

Keywords: STING agonist; PBAE nanoparticle formulation; Cancer immunotherapy; CDNs; Cyclic dinucleotides; STING; Stimulator of Interferon Receptor; PBAEs; poly(beta-amino ester)s; IFN; interferon; SEAP; secreted embryonic alkaline phosphatase; cGAS; cyclic GMP-AMP

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Developmental and extrahepatic physiological functions of SREBP pathway genes in mice

Keywords: AAV; adeno-associated virus; ACC; acetyl-CoA carboxylase; AD; Alzheimer's disease; ADD1; adipocyte determination- and differentiation-dependent factor 1; APP; amyloid precursor protein; Api6; apoptosis inhibitor 6; ApoE; apolipoprotein E; ATF6; activati

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

STING Signaling Promotes Inflammation in Experimental Acute Pancreatitis

Keywords: Mouse Model; Apoptosis; Signal Transduction; Innate Immunity; ACS; acinar cell culture supernatant; AP; acute pancreatitis; BM; bone marrow; BMDM; BM-derived macrophages; CDE; choline-deficient diet supplemented with DL-ethionine; cGAS; cyclic GMP-AMP syn

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effect of monophosphoryl lipid A, a detoxified lipid A derivative, in photothrombotic model of unilateral selective hippocampal ischemia in rat

Keywords: MPL; monophosphoryl lipid A; LPS; lipopolysaccharide; TLR4; toll like receptor 4; i.c.v; intracerebroventricular; TTC; triphenyltetrazolium chloride; RAWM; radial arm water maze test; PA; passive avoidance test; NF-κB; nuclear factor kappa beta; TNF-α;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Nontypeable Haemophilus influenzae DNA stimulates type I interferon expression via STING signaling pathway

Keywords: NTHI; IFN-β; STING; TBK1; IRF3; cGAS;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women

Keywords: BSA; bovine serum albumin; IFN; interferon; IR; insulin resistance; IRF3; interferon regulatory factor 3; ISG; interferon-stimulated genes; ISRE; interferon-sensitive/stimulated response element; LPS; lipopolysaccharides; MyD88; myeloid differentiation pr

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Functional, signalling and transcriptional differences of three distinct type I IFNs in a perciform fish, the mandarin fish Siniperca chuatsi

Keywords: Type I IFN; Cytokine receptor family B; CRFB; STAT1; STAT2; IRF3; IRF7; Teleost fish;

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

Human microglia and astrocytes express cGAS-STING viral sensing components

Keywords: AMP; adenosine monophosphate; ATCC; American type tissue collection; ANOVA; analysis of variance; BDNA; B-form DNA; CNS; central nervous system; cDNA; complementary DNA; cGAS; cyclic GMP-AMP synthase; DAI; DNA-dependent activator of interferon-regulatory

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

SJL bone marrow-derived macrophages do not have IRF3 mutations and are highly susceptible to Theiler's virus infection

Keywords: IRF3; Macrophages; Picornavirus; Theiler's virus; Virus persistence;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Intracellular DNA sensing pathway of cGAS-cGAMP is decreased in human newborns and young children

Keywords: CBMCs; cord blood mononuclear cells; CBP; CREB-binding protein; cGAS; cyclic GMP-AMP synthase; cGAMP; cyclic GMP-AMP; EBV; Epstein-Barr virus; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HCMV; human cytomegalovirus; HSV-1; herpes simplex virus type 1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Bis(monoacylglycero)phosphate inhibits TLR4-dependent RANTES production in macrophages

Keywords: ABC; ATP-binding cassette transporter; BMP; bis(monoacylglycerophosphate); IL-6; interleukin 6; IRF3; interferon regulatory factor 3; LPS; lipopolysaccharide; oxLDL; oxidized low-density lipoprotein; MBCD; methyl-β-cyclodextrin; MyD88; myeloid differenti

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Human B cells fail to secrete type I interferons upon cytoplasmic DNA exposure

Keywords: IFN I; type I interferon(s); IFI16; interferon-inducible protein 16; cGAMP; cyclic GMP-AMP; cGAS; cGAMP synthase; STING; stimulator of interferon genes; TBK1; TANK-binding kinase 1; IRF3; interferon regulatory factor 3; ISG; interferon-stimulated genes; P

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Expanding perspectives on the significance of mitophagy in cancer

Keywords: ALS; amyotrophic lateral sclerosis; AR; androgen receptor; ASC; apoptosis-associated speck-like protein containing a CARD; ATM; ataxia telangiectasia mutated; BCL-2; breakpoint cluster locus-2; BCL-XL; BCL2-like 1 long; BNIP3; BCL2 interacting protein 3;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization and biological function analysis of the TRIM47 gene from common carp (Cyprinus carpio)

Keywords: SVCV; Spring viremia of carp virus; SVC; Spring viremia of carp; TRIM47; the tripartite motif protein 47; IRF3; interferon regulator factor 3; ISRE; interferon-stimulated response element; MS-222; 3-aminobenzoic acid ethyl ester methanesulfonate; HZAU; Hu

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Zebrafish STAT6 negatively regulates IFNφ1 production by attenuating the kinase activity of TANK-binding kinase 1

Keywords: STAT6; Negative regulator; Interferon; TBK1; Zebrafish; CIP; calf intestinal phosphatase; CPE; cytopathic effect; EPC; epithelioma papulosum cyprini; GAS; interferon gamma activated sequence; IFN; interferon; IRF; IFN regulatory factor; IRF3; interferon r

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Poly (I:C) impairs NO donor-induced relaxation by overexposure to NO via the NF-kappa B/iNOS pathway in rat superior mesenteric arteries

Keywords: 1400W; N-([3-(aminomethyl)phenyl]methyl)ethanimidamide dihydrochloride; ACh; acetylcholine; ANOVA; analysis of variance; BAY41-2272; 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine; BAY58-2667; 4-[[(4-carboxybu

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2017 سفارش ترجمه

Modifications to the composition of the hyphal outer layer of Aspergillus fumigatus modulates HUVEC proteins related to inflammatory and stress responses

Keywords: AiP; programed cell death 6-interacting protein; AKT; protein kinase B; ASK1; mitogen-activated protein kinase 5; BAD; BLC2-associated agonist of cell death; BAX; BCL2-associated X protein; CD-142; tissue factor; cFOS; FBJ Murine osteosarcoma viral oncoge

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2017 سفارش ترجمه

Diverse roles of HDAC6 in viral infection: Implications for antiviral therapy

Keywords: HDAC6; Viral infection; Viral pathogenesis; Antiviral therapy; CBP; cAMP response element-binding protein (CREB) binding protein; HCV; hepatitis C virus; HDAC6; histone deacetylase 6; HIV; human immunodeficiency virus; IAV; influenza A virus; IFN; interfe

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

IRF3 is involved in human acute myeloid leukemia through regulating the expression of miR-155

Keywords: IRF3; Acute myeloid leukemia; miR-155;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Identification and functional characterization of miiuy croaker IRF3 as an inducible protein involved regulation of IFN response

Keywords: IRF3; Antiviral response; Evolutionary analysis; Cellular localization

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

ASF1a enhances antiviral immune response by associating with CBP to mediate acetylation of H3K56 at the Ifnb promoter

Keywords: ASF1a; anti-silencing function 1a; CBP; CREB binding protein; TLRs; Toll-like receptors; RLRs; RIG-I-like receptors; IRF3; interferon regulatory factor 3; VSV; vesicular stomatitis virus; SEV; simian enterovirus; IFN-β; interferon beta; QPCR; quantitativ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The function of feline stimulator of interferon gene (STING) is evolutionarily conserved

Keywords: Feline; STING; Type I IFN; Activation; STING; Stimulator of interferon genes; ER; Endoplasmic reticulum; IRF3; Interferon regulatory factor 3; NF-κB; Nuclear factor kappa-light-chain-enhancer of activated B cells; JNK; c-jun N-terminal kinase; AP-1; Acti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes

Keywords: PUVA; 8-methoxypsoralen plus UVA; RIG-1; retinoic acid induced gene 1; MDA5; melanoma differentiation associated gene 5; MAVS; mitochondrial antiviral signaling protein; TBK; TANK-binding kinase 1; IKKε; inhibitor of kappaB kinase epsilon; IRF3; interfer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Mosla scabra flavonoids ameliorate the influenza A virus-induced lung injury and water transport abnormality via the inhibition of PRR and AQP signaling pathways in mice

Keywords: MF; total flavonoids extracted from Mosla Scabra; IAV; influenza A virus; LD50; 50% lethal dose; RFQ-PCR; Real-time Fluorescence Quantitative Polymerase Chain Reaction; IC50; 50% influenza virus-inhibitory concentration; HDF-1; 5-hydroxy-6,7-dimethoxyflav

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Esterase D enhances type I interferon signal transduction to suppress foot-and-mouth disease virus replication

Keywords: Foot-and-mouth disease virus; Esterase D; IRF3; Interferon-stimulated genes; Antiviral response;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

c-Cbl-mediated ubiquitination of IRF3 negatively regulates IFN-β production and cellular antiviral response

Keywords: c-Cbl; IRF3; Ubiquitination; Antiviral response;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewUpdate on hepatitis E virology: Implications for clinical practice

Keywords: 7mG; 7-methylguanylate; CSF; cerebrospinal fluid; gt; genotype; HCV; hepatitis C virus; HEV; hepatitis E virus; ESCRT; endosomal sorting complexes required for transport; IFN; interferon; IRF3; interferon regulatory factor 3; ISG; interferon-stimulated ge

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection

Keywords: CARMA3; CARD10; IRF3; NF-κB; viral infection

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه