دانلود مقالات ISI درباره هدف پستانداران رپامایسین + ترجمه فارسی

Evolution, regulation, and function of porcine selenogenome

Keywords: هدف پستانداران رپامایسین; ACC; acetyl CoA carboxylase; AKT; protein kinase B; Cys; cysteine; DIO1; type 1 iodothyronine deiodinase; ER; endoplasmic reticulum; FAS; fatty acid synthase; FOXO1; forkhead box protein O1; GPX; glutathione peroxidase; INSR; insulin receptor; MIEN; migra

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress

Keywords: هدف پستانداران رپامایسین; AKT; protein kinase B (PKB); AMPK; protein kinase AMP-activated catalytic subunit alpha 1 (PRKAA1); HOTAIR; HOX transcript antisense RNA; Keap1; kelch like ECH associated protein 1; mTOR; mammalian target of rapamycin; NBR2; neighbor of BRCA1 gene 2; Nrf2

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Analysis of spontaneous resolution of cytomegalovirus replication after transplantation in CMV-seropositive patients with pretransplant CD8+IFNG+ response

Keywords: هدف پستانداران رپامایسین; Solid organ transplantation; Cytomegalovirus infection; T-cell response; QuantiFERON-CMV assay; Interferon-gamma; D+/D-; CMV-seropositive/CMV-seronegative donor; IFNG; interferon-gamma; mTOR; mammalian target of rapamycin; PD-1; programmed death 1; QF; Qu

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Class I PI3K inhibitor ZSTK474 attenuates experimental autoimmune neuritis by decreasing the frequency of Th1/Th17 cells and reducing the production of proinflammatory cytokines

Keywords: هدف پستانداران رپامایسین; AUC; area under the curve; CMAP; compound muscle action potential; DAPI; 4′,6-diamidino-2- phenylindole; dpi; days post-inoculation; EAN; experimental autoimmune neuritis; ELISA; enzyme-linked immunosorbent assay; EMG; electromyography; GAPDH; glycerald

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy induced by cardamonin is associated with mTORC1 inhibition in SKOV3 cells

Keywords: هدف پستانداران رپامایسین; FKBP12; FK506 binding protein 12 kDa; FRB domain; FKBP12-rapamycin binding domain; mTOR; mammalian target of rapamycin; mTORC1/2; mTOR complex 1/2; NF-κB; nuclear factor-κB; Raptor; regulatory associated protein of mTOR; Rictor; rapamycin-insensitive

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity

Keywords: هدف پستانداران رپامایسین; Cancer cells; PPARγ agonist; PPARγ antagonist; Therapeutic agents; Tumorigenicity; ACC; Acetyl-CoA carboxylase; AKR1B10; Alde-keto reductase 1B10; Alpha-ESA; Alpha-eleostreac acid; ACLY; ATP citrate lyase; BADGE; Bisphenol-A-diglycidyl-etter; CSCs; Canc

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Elevated phospholipase D activity in androgen-insensitive prostate cancer cells promotes both survival and metastatic phenotypes

Keywords: هدف پستانداران رپامایسین; Prostate cancer; Prostate cancer phospholipase D; Survival; Apoptosis; Metastasis; FBS; fetal bovine serum; HA; hemagglutinin; mTOR; mammalian target of rapamycin; PA; phosphatidic acid; PARP; poly-ADP-ribose polymerase; PLD; phospholipase D;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Induction of REDD1 via AP-1 prevents oxidative stress-mediated injury in hepatocytes

Keywords: هدف پستانداران رپامایسین; AP-1; activator protein-1; ActD; actinomycin-D; ARE; antioxidant response elements; BHA; butylated hydroxy anisole; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; DMEM; Dulbecco's modified Eagle medium; DPI; diphenyleneiodonium chloride; H2O2; hydrogen

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

AMPK promotes survival and adipogenesis of ischemia-challenged ADSCs in an autophagy-dependent manner

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated protein kinase; ADSCs; adipose-derived stem cells; OGD; oxygen-glucose deprivation; mTOR; mammalian target of rapamycin; BML-275; Dorsomorphin; PPARγ; peroxisome proliferator-activated receptor gamma; C/EBP; CCAAT/enhancer binding pro

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Extracellular histones activate autophagy and apoptosis via mTOR signaling in human endothelial cells

Keywords: هدف پستانداران رپامایسین; PTMs; post-translational modifications; PAMPs; pathogen-associated molecular patterns; TLRs; Toll-like receptors; HUVEC; human umbilical vein endothelial cells; AMPK; AMP-activated protein kinase; Akt; serine/thPGI2, prostacyclin; TXA2; thromboxane A2; CO

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

ZBTB38, a novel regulator of autophagy initiation targeted by RB1CC1/FIP200 in spinal cord injury

Keywords: هدف پستانداران رپامایسین; ATG2; autophagy-related protein 2; ATG13; autophagy-related protein 13; ATG14; autophagy-related protein 14; ATG101; autophagy-related protein 101; ATM; ataxia telangiectasia-mutated gene; BECN1; the homologue of yeast autophagy-related protein 6; CCK-8;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Pharmacological inhibition of 2-arachidonoilglycerol hydrolysis enhances memory consolidation in rats through CB2 receptor activation and mTOR signaling modulation

Keywords: هدف پستانداران رپامایسین; JZL184; Rat; Monoacylglycerol lipase (MAGL); Inhibitory avoidance; Fear memory; Behavior; JZL184 [4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic acid 4-nitrophenyl ester]; MAGL inhibitor; SR141716 [5-(4-chlorophenyl)-1-(2,4-dichlorophen

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway

Keywords: هدف پستانداران رپامایسین; ACC; acetyl-CoA carboxylase; Ac-Lys; acetylated lysine; AMPK; AMP-activated protein kinase; BMMCs; bone marrow-derived mast cells; HSA; human serum albumin; IKK; IκB kinase; IL-6; interleukin-6; JNK; c-Jun N-terminal kinase; LAT; linker for activation of

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

HER2-targeted gold nanoparticles potentially overcome resistance to trastuzumab in gastric cancer

Keywords: هدف پستانداران رپامایسین; Gold nanoparticle; Trastuzumab resistance; HER2; Gastric cancer; Autophagy; Tmab; trastuzumab; HER2; human epidermal growth factor receptor 2; AuNP; gold nanoparticle; ECD; extracellular domain; ADCC; antibody-dependent cellular cytotoxicity; PTEN; phosph

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Nesfatin-1 functions as a switch for phenotype transformation and proliferation of VSMCs in hypertensive vascular remodeling

Keywords: هدف پستانداران رپامایسین; α-SMA; α-smooth muscle actin; BCA; Bicinchoninic acid; CCK-8; Cell counting kit-8; CDK2; cyclin dependent kinase 2; DAPI; 4′,6-diamidino-2-phenylindole; DBP; diastolic blood pressure; DMEM; Dulbecco's modified Eagle's medium; DHE; dhydroethidium; EdU;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Neural progenitors derived from Tuberous Sclerosis Complex patients exhibit attenuated PI3K/AKT signaling and delayed neuronal differentiation

Keywords: هدف پستانداران رپامایسین; TSC; Tuberous Sclerosis Complex; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; LOH; loss of heterozygosity; iPSCs; induced pluripotent stem cells; NPCs; neural progenitor cells; PI3K; phosphoinositide 3-kinase; SENs; subependymal nodules; S

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells

Keywords: هدف پستانداران رپامایسین; Imatinib resistance; Autophagy; miR-199a-5p; miR-199b-5p; WNT2; Chronic myeloid leukemia (CML); 3-MA; 3-methyladenine; AVO; acidic vesicular organelle; CML; chronic myeloid leukemia; CQ; chloroquine; DMSO; dimethyl sulfoxide; HRP; horseradish peroxidase;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Disruption of peroxisome function leads to metabolic stress, mTOR inhibition, and lethality in liver cancer cells

Keywords: هدف پستانداران رپامایسین; Peroxisome; Peroxisomal biogenesis factor 2; Mammalian target of rapamycin complex 1; Metabolic stress; Human hepatocellular carcinoma; PEXs; peroxins; PTS; peroxisome targeting signal; PBD; peroxisome biogenesis disorder; ZS; Zellweger syndrome; HCC; hum

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in obesity

Keywords: هدف پستانداران رپامایسین; AICAR; 5-aminoimidazole-4-carboxamide 1-β-d-ribofuranoside; ATMs; adipose tissue macrophages; CC; compound C; Ctrl; control; ERK1/2; p44/42 mitogen-activated protein kinase; FNDC5; fibronectin type III domain-containing protein 5; GTT; glucose tolerance

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Ca2+ signaling and Src-kinases-controlled cellular functions

Keywords: هدف پستانداران رپامایسین; Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance

Keywords: هدف پستانداران رپامایسین; ABCB1; ATP-binding cassette sub-family B member 1; AML; acute myeloid leukaemia; AMPK; adenosine monophosphate-activated protein kinase; ATM; Ataxia-telangiectasia mutated; AURKA; aurora kinase A; BER; base excision repair; Bim; B-cell lymphoma 2 interact

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Stimulation of the adenosine A3 receptor, not the A1 or A2 receptors, promote neurite outgrowth of retinal ganglion cells

Keywords: هدف پستانداران رپامایسین; Adenosine receptors; Neuroregeneration; Glaucoma; Akt; 2-Cl-IB-MECA; IOP; intraocular pressure; RGC; retinal ganglion cell; NTG; normal tension glaucoma; AC; adenylyl cyclase; cAMP; cyclic adenosine monophosphate; PI3K; phosphoinositide 3-kinase; AdoR; ad

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-neuroinflammatory effects of Ginkgo biloba extract EGb761 in LPS-activated primary microglial cells

Keywords: هدف پستانداران رپامایسین; Neurodegeneration; Prostaglandin E2; Cyclooxygenase; Cytokines; Neuroinflammation; Alzheimer's disease; EGb 761; Extract Ginkgo biloba 761; PG; prostaglandin; COX; cyclooxygenase; cPLA2; cytosolic phospholipase A2; IkappaBalpha; inhibitor of kappa B alpha

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Early dietary restriction in rats alters skeletal muscle tuberous sclerosis complex, ribosomal s6 and mitogen-activated protein kinase

Keywords: هدف پستانداران رپامایسین; Muscle, skeletal; Rats; Diet reducing; Fetal growth retardation; TOR serine-threonine kinase; Mitogen-activated protein kinase phosphatases; 4EBP1; 4E binding protein-1; AMP; adenosine monophosphate-activated protein; CON; control; eIF4E; eukaryotic tra

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Glucose dependent miR-451a expression contributes to parathyroid hormone mediated osteoblast differentiation

Keywords: هدف پستانداران رپامایسین; Ovx; Ovariectomy; PTH; Parathyroid Hormone; miRNA; MicroRNA; μCT; Micro-computed tomography; BMD; Bone mineral density; BV/TV; Bone volume/Total volume; SMI; Structural model index; Tb.N; Trabecular number; Conn Dn; Connection density; Tb.Sp; trabecular

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

STAT3: The art of multi-tasking of metabolic and immune functions in obesity

Keywords: هدف پستانداران رپامایسین; Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H2S formation

Keywords: هدف پستانداران رپامایسین; AOAA; aminooxyacetic acid; CBS; cystathionine β synthase; CD86; cluster of differentiation 86; CNS; central nervous system; DAPI; 4,6-diamidino-2-phenylindole; DAO; d-amino acid oxidase; GFAP; glial fibrillary acidic protein; HBSS; Hanks Balanced Salt So

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization

Keywords: هدف پستانداران رپامایسین; 3-MA; 3-Methyl Adenine; Akt; Protein kinase B; AMP; Adenosine monophosphate; AMPK; AMP-activated protein kinase; Atg; Autophagy related genes; ATP; Adenosine triphosphate; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; BCL-2; B-

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Aberrant regulation of the Akt signaling network by human cytomegalovirus allows for targeting of infected monocytes

Keywords: هدف پستانداران رپامایسین; Cytomegalovirus; Monocytes; Small-molecule inhibitor; HCMV; human cytomegalovirus; h; hour; EGF; epidermal growth factor; EGFR; EGF receptor; αvβ3; alpha v beta 3 integrin; gB; glycoprotein B; gH; glycoprotein H; PI3K; phosphoinositide 3-kinase; PTEN; p

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

The GABAAα5-selective Modulator, RO4938581, Rescues Protein Anomalies in the Ts65Dn Mouse Model of Down Syndrome

Keywords: هدف پستانداران رپامایسین; AD; Alzheimer's disease; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BDNF; brain-derived neurotrophic factor; CFC; context fear conditioning; CS; context-shock; DS; Down syndrome; FDR; false discovery rate; FvN; failed vs. normal learni

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

CDC42-related genes are upregulated in helper T cells from obese asthmatic children

Keywords: هدف پستانداران رپامایسین; Asthma; obesity; helper T cell transcriptome; children; FRC; Functional residual capacity; FVC; Forced vital capacity; GTP; Guanosine triphosphate; MAPK; Mitogen-activated protein kinase; mTOR; Mammalian target of rapamycin; qRT-PCR; Quantitative RT-PCR;

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

Ferrosenescence: The iron age of neurodegeneration?

Keywords: هدف پستانداران رپامایسین; TE; transposable elements; IRP-2; iron regulatory protein-2; BACE-1; beta-secretase 1; APP; amyloid precursor protein; FPN; ferroportin; Tf; transferrin; TFR-1; transferrin receptor-1; IRE; iron-responsive elements; mtDNA; mitochondrial DNA; DNMT-3A and D

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy in ischemic stroke

Keywords: هدف پستانداران رپامایسین; 3-MA; 3-methyladenine; Aβ; amyloid β; AIF; apoptosis-inducing factor; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; Atg; autophagy-related genes; ATP; adenosine 5′-triphosphate; BBB; blood-brain ba

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

Keywords: هدف پستانداران رپامایسین; 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5′-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of Nrf2 signaling by natural products-can it alleviate diabetes?

Keywords: هدف پستانداران رپامایسین; Nrf2; type 2 diabetes; natural products; hyperglycemia; cellular stress; insulin sensitivity; β-cell function; vascular complications; AGE; advanced glycation end products; AhR; arylhydrocarbon receptor; AMPK; AMP-activated kinase; ARE; antioxidant respo

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2018 سفارش ترجمه

Huge soft tissue PEComa with aggressive lung and bone metastases

Keywords: هدف پستانداران رپامایسین; Perivascular epithelioid cell tumors; Mammalian target of rapamycin; mTOR inhibitors;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and biological evaluation of novel 3H-imidazole [4,5-b] pyridine derivatives as selective mTOR inhibitors

Keywords: هدف پستانداران رپامایسین; Mammalian target of rapamycin; mTOR inhibitors; 3H-Imidazo [4,5-b] pyridine; Antitumor; Synthesis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Novel function of Porphyromonas gingivalis gingipains in the PI3K/Akt signaling pathway

Keywords: هدف پستانداران رپامایسین; PI3K; phosphatidylinositol-3 kinase; GSK3; glycogen synthase kinase 3; mTOR; mammalian target of rapamycin; PDK1; 3-phosphoinositide-dependent protein kinase 1; LPS; lipopolysaccharide; Porphyromonas gingivalis; Virulence factors; Gingipains; PI3K/Akt sig

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Oncogenic mutations of PIK3CA and HRAS in carcinoma of cervix in South Indian women

Keywords: هدف پستانداران رپامایسین; Oncogenic mutations; Cervical cancer; Peripheral blood; PCR-CTPP method; PIK3CA; Phosphatidylinositol-4,5-Bisphosphate; 3-Kinase Catalytic Subunit Alpha; HRAS; Harvey rat sarcoma viral oncogene homolog; EGF; Epidermal Growth Factor; PDGF; Platelet Derived

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of autophagy aggravated 4-nitrophenol-induced oxidative stress and apoptosis in NHPrE1 human normal prostate epithelial progenitor cells

Keywords: هدف پستانداران رپامایسین; 4-Nitrophenol; NHPrE1; Oxidative stress; Apoptosis; Autophagy; mTOR; PNP; 4-nitrophenol; DMEM; Dulbecco's modified Eagles medium; FBS; fetal bovine serum; ITS; insulin-transferrin-selenium-X; BPE; bovine pituitary extract; EGF; epidermal growth factor; 3-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Curcumin synergizes with the endocannabinoid reuptake inhibitor OMDM-2 in human MCF-7 breast cancer and U-87 glioblastoma cells

Keywords: هدف پستانداران رپامایسین; Δ9-THC; Delta-9-tetrahydrocannabinol; 2-AG; 2-arachidonoylglycerol; AEA; Anandamide; BCL2; B-cell CLL/lymphoma 2; CB-1; Cannabinoid receptor 1; CB-2; Cannabinoid receptor 2; CI; Combination Index; CXCR4; chemokine receptor type 4; DDS; Drug delivery syst

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway

Keywords: هدف پستانداران رپامایسین; Resveratrol; Osteoarthritis; Autophagy; AMP activated protein kinase; Mammalian target of rapamycin; ADAMTS5; a disintegrin and metalloproteinase with thrombospondin motifs 5; AMPK; AMP activated protein kinase; DMM; destabilization of the medial meniscu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated protein kinase; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; BAF; Bafilomycin A1; BiP (GRP78); Binding immunoglobulin Protein (78 kDa glucose regulated protein); BZ; bortezomib; CHOP; C/EBP-Homolog

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Structural analysis of ribosomal RACK1 and its role in translational control

Keywords: هدف پستانداران رپامایسین; RACK1; Receptor for activated C-Kinase 1; rRNA; Ribosomal RNA; mRNA; Messenger RNA; PKC; Protein kinase C; eIF6; Eukaryotic initiation factor 6; eIF3; Eukaryotic initiation factor 3; eIF4E; Eukaryotic initiation factor 4E; Src; Sarcoma family kinase; Scp1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Absence of the kinase S6k1 mimics the effect of chronic endurance exercise on glucose tolerance and muscle oxidative stress

Keywords: هدف پستانداران رپامایسین; S6K1; Exercise; Glycemic control; Metabolic phenotyping; Reactive oxidative species; HFD; high-fat diet; ROS; reactive oxygen species; TCA; tricarboxylic acid cycle; mTOR; mammalian target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Rapamycin-Sensitive Late-LTP is Enhanced in the Hippocampus of IL-6 Transgenic Mice

Keywords: هدف پستانداران رپامایسین; ANOVA; analysis of variance; ACSF; artificial cerebral-spinal fluid; CNS; central nervous system; DNA; deoxyribonucleic acid; ERK; extracellularly regulated kinase; fEPSP; field excitatory postsynaptic potential; HFS; high-frequency stimulation; I/O; inpu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats

Keywords: هدف پستانداران رپامایسین; AD; Alzheimer's disease; AED; anti-epileptic drug; BSA; bovine serum albumin; cDNA; complementary deoxyribonucleic acid; Co-IP; co-immunoprecipitation; CSF; cerebrospinal fluid; DAB; 3,3-diaminobenzidine; DAPI; 4,6-diamidino-2-phenylindole; FITC; fluore

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

Keywords: هدف پستانداران رپامایسین; α-SYN; alpha synuclein; β-TrCP; β-transducin repeat containing E3 ubiquitin protein ligase; Aβ; amyloid beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ASK1; apo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Dual Inhibition of Mnk2 and FLT3 for potential treatment of acute myeloid leukaemia

Keywords: هدف پستانداران رپامایسین; Mnk inhibitor; FLT3 inhibitor; Dual inhibitor; AML; Drug discovery; Anti-leukaemic agent; AML; acute myeloid leukaemia; CDK; cyclin-dependent kinase; eIF; eukaryotic initiation factor; Erk; extracellular signal-regulated kinase; FLT3; Fms-like tyrosine ki

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Optimal ratios of essential amino acids stimulate β-casein synthesis via activation of the mammalian target of rapamycin signaling pathway in MAC-T cells and bovine mammary tissue explants

Keywords: هدف پستانداران رپامایسین; mammalian target of rapamycin; signaling protein; milk protein synthesis; MAC-T cell; bovine mammary tissue explant;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه