دانلود مقالات ISI درباره هدف پستانداران رپامایسین + ترجمه فارسی

Everolimus for the Treatment of Tuberous Sclerosis Complex-Related Cardiac Rhabdomyomas in Pediatric Patients

Keywords: هدف پستانداران رپامایسین; cardiac tumors; hamartomas; mTOR inhibition; infants; cRHM; Cardiac rhabdomyoma; mTOR; Mammalian target of rapamycin; SEGA; Subependymal giant cell astrocytoma; TSC; Tuberous sclerosis complex;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Optimal ratios of essential amino acids stimulate β-casein synthesis via activation of the mammalian target of rapamycin signaling pathway in MAC-T cells and bovine mammary tissue explants

Keywords: هدف پستانداران رپامایسین; mammalian target of rapamycin; signaling protein; milk protein synthesis; MAC-T cell; bovine mammary tissue explant;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Novel anti-prostate cancer scaffold identified by the combination of in silico and cell-based assays targeting the PI3K-AKT-mTOR pathway

Keywords: هدف پستانداران رپامایسین; AKT; protein kinase B; AR; androgen receptor; mTOR; mammalian target of rapamycin; PI3K; phosphatidylinositol-3-kinase; S6; ribosomal protein S6 kinase; SAR; structureactivity relationship; SBVS; structure-based virtual screening; In silico screening; Pro

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells-Implications for age-related macular degeneration (AMD)

Keywords: هدف پستانداران رپامایسین; 9-1-1 complex; complex of Rad9 Rad1 and Hus1 proteins; A2E; N-retinylidene-N-retinylethanol-amine; AtRal; all-trans retinal; AMD; age-related macular degeneration; AMPK; AMP-activated protein kinase; Atg; autophagy-related gene; ATM; ataxia-telangiectasia

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Mammalian target of rapamycin signaling and ubiquitin proteasome-related gene expression in 3 different skeletal muscles of colostrum- versus formula-fed calves

Keywords: هدف پستانداران رپامایسین; mammalian target of rapamycin; ubiquitin-proteasome system; muscle; neonatal calf;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

(−)-UB006: A new fatty acid synthase inhibitor and cytotoxic agent without anorexic side effects

Keywords: هدف پستانداران رپامایسین; FAS fatty acid synthase; C75 derivatives; CPT1 carnitine palmitoyltransferase 1; Ovarian cell cancer; 18S; 18S ribosomal RNA; BIP; binding immunoglobulin protein; BSA; bovine serum albumin; CASP3; caspase-3; CPT1; carnitine palmitoyltransferase 1; DDIT4/R

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Impact of chemotherapy-induced neutropenia (CIN) and febrile neutropenia (FN) on cancer treatment outcomes: An overview about well-established and recently emerging clinical data

Keywords: هدف پستانداران رپامایسین; ABCC1/MRP; ATP binding cassette subfamily C member 1/ multidrug resistance protein; ABVD; doxorubicine-bleomycin-vinblastine-dacarbazine; AC; doxorubicin-cyclophosphamide; ANC; absolute neutrophil count; ASCO; American Society of Clinical Oncology; AUC; a

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

ALA-PDT suppressing the cell growth and reducing the lipogenesis in human SZ95 sebocytes by mTOR signaling pathway in vitro

Keywords: هدف پستانداران رپامایسین; ALA; 5-aminolevulinic acid; PDT; photodynamic therapy; SREBP; sterol-regulatory element binding proteins; PPAR; peroxisome proliferator-activated receptor; mTOR; mammalian target of rapamycin; p70; S6 K p70S6 Kinase; 4E-BP1; eukaryotic translation initiat

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis

Keywords: هدف پستانداران رپامایسین; Triglyceride; Insulin Signaling; Gene Regulation; Signal Transduction; DNL; de novo lipogenesis; HFD; high-fat diet; KCTD17; potassium channel tetramerization domain containing 17; KO; knockout; LC/MS-MS; liquid chromatography-tandem mass spectrometry;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Tau mRNA 3′UTR-to-CDS ratio is increased in Alzheimer disease

Keywords: هدف پستانداران رپامایسین; MAPT; Microtubule associated protein tau; UTR; untranslated region; CDS; coding DNA sequence; mRNA; messenger RNA; mTOR; mammalian target of rapamycin; 5′TOP; 5′ terminal oligopyrimidine; RIN; RNA integrity number; Tau (MAPT); 3′UTR; CDS; mRNA; Alzh

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Frequency and Prognostic Value of PTEN Loss in Patients with Upper Tract Urothelial Carcinoma Treated with Radical Nephroureterectomy

Keywords: هدف پستانداران رپامایسین; kidney; ureter; carcinoma; neoplasm recurrence; local; PTEN phosphohydrolase; IHC; immunohistochemistry; LVI; lymphovascular invasion; mTOR; mammalian target of rapamycin; PI3K; phosphatidylinositol 3-kinase; PTEN; phosphatase and tensin homolog; RNU; rad

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

The alteration of autophagy and apoptosis in the hippocampus of rats with natural aging-dependent cognitive deficits

Keywords: هدف پستانداران رپامایسین; MWM; Morris water maze; HE; Hematoxylin-eosin; Bax; Bcl-2 associated X Protein; Bcl-2; B-cell lymphoma-2; ULK-1; unc-51-like kinase 1; Beclin-1; B cell lymphoma/leukemia-2 binding protein 1; LC3; light chain 3; Akt; protein kinase B; PI3K; phosphatidylino

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Autophagy inhibits C2-ceramide-mediated cell death by decreasing the reactive oxygen species levels in SH-SY5Y cells

Keywords: هدف پستانداران رپامایسین; Atg; autophagy-related proteins; mTOR; mammalian target of rapamycin; Akt/PKB; protein kinase B; JNK; c-Jun N-terminal kinase; ROS; reactive oxygen species; ERK; extracellular signal-regulated kinase; 3-MA; 3-methyadenine; H2DCFDA; 2′,7′-dichlorofluor

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4

Keywords: هدف پستانداران رپامایسین; ROS; Reactive oxygen species; PKA; Protein kinase A; NOX; NADPH oxidase; PTP1B; Protein tyrosine phosphatase 1B; CaMK; Calmodulin Kinase; mTOR; Mammalian target of rapamycin; AAV; Adeno-associated virus; CIRKO; Cardiac insulin receptor knockout; IGF-1; In

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Near-infrared photothermal therapy using EGFR-targeted gold nanoparticles increases autophagic cell death in breast cancer

Keywords: هدف پستانداران رپامایسین; (TNBC); triple negative breast cancer; (NIR-PTT); near infrared-photothermal therapy; (EGFR); epidermal growth factor receptor; (anti-EGFR-GNs); anti-EGFR antibody-conjugated gold nanorods; (GNs); Gold nanorods; (LC3); microtubule-associated protein light

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Differences in Dural Penetration of Clival Chordomas Are Associated with Different Prognosis and Expression of Platelet-Derived Growth Factor Receptor-β

Keywords: هدف پستانداران رپامایسین; Clival chordomas; Dura mater; Penetration; Platelet-derived growth factor receptor-β; Prognosis; mTOR; Mammalian target of rapamycin; NTR; Nontotal resection; OS; Overall survival; PDGFR-β; Platelet-derived growth factor receptor-β; PFS; Progression-fr

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Role of Microglia Autophagy in Microglia Activation After Traumatic Brain Injury

Keywords: هدف پستانداران رپامایسین; Apoptosis; Autophagy; Microglia; Traumatic brain injury; 3-MA; 3-Methyladenine; Iba-1; Ionized calcium-binding adapter molecule 1; ICV; Intracerebroventricular; IL-1β; Interleukin-1β; LC3; Protein light chain 3; mTOR; Mammalian target of rapamycin; PBS;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

PML-RARα stabilized by zinc in human acute promyelocytic leukemia NB4 cells

Keywords: هدف پستانداران رپامایسین; Zinc homeostasis; Acute promyelocytic leukemia; PML-RARα degradation; Nitric oxide; Apoptosis; APL; acute promyelocytic leukemia; ATRA; all-trans retinoic acid; ATO; arsenic trioxide; CHX; cycloheximide; C-PTIO; carboxy-2-phenyl-4,4,5,5-tetramethylimidaz

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Intraventricular administration of Tenebrio molitor larvae extract regulates food intake and body weight in mice with high-fat diet-induced obesity

Keywords: هدف پستانداران رپامایسین; Appetite; Diet-induced obesity; Hypothalamus; Neuropeptide; Tenebrio molitor larvae; AgRP; agouti-related peptide; ATF4; activating transcription factor 4; CHOP; c/EBP-homologous protein; eIF2α; α subunit of eukaryotic translation initiation factor 2; E

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-inflammatory effect of Cortex Eucommiae via modulation of the toll-like receptor 4 pathway in lipopolysaccharide-stimulated RAW 264.7 macrophages

Keywords: هدف پستانداران رپامایسین; CE; Cortex Eucommiae; LPS; lipopolysaccharide; HPLC; high-performance liquid chromatography; RT-PCR; reverse transcriptase-polymerase chain reaction; IC50; inhibitory concentration of 50%; TLR-4; toll-like receptor 4; Myd88; myeloid differentiation primar

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Ginkgo biloba L. attenuates spontaneous recurrent seizures and associated neurological conditions in lithium-pilocarpine rat model of temporal lobe epilepsy through inhibition of mammalian target of rapamycin pathway hyperactivation

Keywords: هدف پستانداران رپامایسین; CA; Cornu Ammonis; DAB; 3,3ˈ-Diaminobenzidine; DG; Dentate gyrus; DPX; dibutyl phthalate xylene; GBbf; Ginkgo biloba butanol fraction; GBe; hydrolyzed ethyl acetate fraction; LiPc; lithium-pilocarpine; mTOR; mammalian target of rapamycin; mTORC1; mammali

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells

Keywords: هدف پستانداران رپامایسین; Polyalthia longifolia; 16-Hydroxycleroda-3,13-dien-15,16-olide; Renal cell carcinoma; Apoptosis; AO/EB; acridine orange and ethidium bromide; Bcl-2; B cell lymphoma 2; ccRCC; clear cell renal cell carcinoma; CD; 16-hydroxycleroda-3,13-dien-15,16-olide; ER

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice

Keywords: هدف پستانداران رپامایسین; PGC-1α; peroxisome proliferator-activated receptor gamma co-activator 1α; TFAM; mitochondrial transcription factor A; BDNF; brain-derived neurotrophic factor; ETC; electron transport chain; OC; old control group; OT; old trained group; YC; young control

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway

Keywords: هدف پستانداران رپامایسین; ADP; adenosine diphosphate; AFC; amino-4-trifluoromethyl coumarin; Akt; protein kinase B; ATP; adenosine triphosphate; Drp1; dynamin-related protein 1; ERK; extracellular signal regulated kinases; Fis1; mitochondrial fission-1 protein; Gp91phox; glycoprot

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Up-regulation of the active form of small GTPase Rab13 promotes macroautophagy in vascular endothelial cells

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated protein kinase; AO; acridine orange; AVOs; acidic vesicular organelles; FGF-2; fibroblast growth factor 2; Grb2; growth factor receptor binding protein 2; Rab13; Ras-related protein in brain 13; HA; hemagglutinin; HRP; Horseradish pero

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Upregulation of Akt signaling enhances femoral fracture healing by accelerating atrophic quadriceps recovery

Keywords: هدف پستانداران رپامایسین; Akt; protein kinase B; BTX; botulinum toxin-A; MHC; myosin heavy chain; TGF-β; transforming growth factor-β; BMSC; bone marrow stromal cells; Acvr IIB; type IIB activin receptor; mTOR; mammalian target of rapamycin; p70S6K; ribosomal protein S6 kinase;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Activating transcription factor 6-dependent sestrin 2 induction ameliorates ER stress-mediated liver injury

Keywords: هدف پستانداران رپامایسین; Ad; adenovirus; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATF6; activating transcription factor 6; ChIP; chromatin immunoprecipitation; CHOP; C/EBP homologous protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxid

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes

Keywords: هدف پستانداران رپامایسین; 4E-BP1; eukaryotic initiation factor 4E-binding protein 1; AMPK; AMP-activated protein kinase; BSA; bovine serum albumin; ConA; concanavalin A; eEF2; eukaryotic elongation factor 2; eIF; eukaryotic initiation factor; ERK; extracellular-signal-regulated

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of brain glucose metabolism ameliorating cognitive impairment in APP/PS1 transgenic mice by electroacupuncture

Keywords: هدف پستانداران رپامایسین; AD; Alzheimer's disease; EA; electroacupuncture; 18F-FDG; 18F-Fluoro-2-deoxy-D-Glucose; PET; positron emission tomography; AMPK; adenosine monophosphate-activated protein kinase; mTOR; mammalian target of rapamycin; Aβ; amyloid-beta; ThS; Thioflavin stai

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Systemic application of sirolimus prevents neointima formation not via a direct anti-proliferative effect but via its anti-inflammatory properties

Keywords: هدف پستانداران رپامایسین; α-SMA; α-smooth muscle actin; BMPC; bone marrow-derived progenitor cells; BMTx; bone marrow transplantation; CFSE; carboxyfluorescein succinimidyl ester; DES; drug-eluting stents; EC; endothelial cells; ICAM-1; intercellular adhesion molecule 1; mTOR; m

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells

Keywords: هدف پستانداران رپامایسین; 3-MA; 3-methyladenine; ADCX; 25-O-acetyl-7,8-didehydrocimigenol 3-O-beta-D-xylopyranoside; TCM; traditional Chinese medicine; HCC; hepatocellular carcinoma; ABC; ATP-binding cassette; ULK1; unc-51-like kinase 1; HCQ; hydroxychloroquine; CTSB; cathepsin B;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Multifaceted anticancer activity of BH3 mimetics: Current evidence and future prospects

Keywords: هدف پستانداران رپامایسین; A1; Bcl-2-related protein A1; AIF; apoptosis-inducing factor; AKT; protein kinase B; AMPK; 5′AMP-activated protein kinase; Bad; Bcl-2-associated death promoter; Bak; Bcl-2-associated killer; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; Bcl

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Endoplasmic reticulum-targeting photosensitizer Hypericin confers chemo-sensitization towards oxaliplatin through inducing pro-death autophagy

Keywords: هدف پستانداران رپامایسین; ROS; reactive oxygen species; ER; endoplasmic reticulum; PDT; photodynamic therapy; HY-PDT; hypericin-mediated photodynamic therapy; mTOR; mammalian target of rapamycin; CHOP; CCAAT/enhancer-binding protein homologous protein; Endoplasmic reticulum (ER);

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2017 سفارش ترجمه

The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1

Keywords: هدف پستانداران رپامایسین; BAG3; BCL2-associated athanogene; mTOR; mammalian target of rapamycin; mTORC1; mammalian target of rapamycin complex 1; TSC; tuberous sclerosis; CASA; chaperone-assisted selective autophagy; CMA; chaperone-mediated autophagy; RE; maximal eccentric resista

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

Keywords: هدف پستانداران رپامایسین; AD; Alzheimer's Disease;; AGEs; advanced glycation endproducts; ALP; autophagy-lysosome pathway; ARF; alternate reading frame; ATGs; autophagy-related proteins; BAG3; Bcl2-associated athanogene 3; Bcl-2; B-cell lymphoma 2; BrdU; 5-bromodeoxyuridine;; CMA;

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2017 سفارش ترجمه

Analysis of ribosomal protein S6 baseline phosphorylation and effect of tau pathology in the murine brain and human hippocampus

Keywords: هدف پستانداران رپامایسین; AD; Alzheimer's disease; Aβ; amyloid-β peptide; FTDP-17; frontotemporal dementia and Parkinsonism linked to chromosome 17; GVD; granulovacuolar degeneration; mTOR; mammalian target of rapamycin; NFTs; neurofibrillary tangles; p70S6K; S6 kinases; PI3K;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

1,25-Dihydroxyvitamin-D3 prevents the development of diabetic cardiomyopathy in type 1 diabetic rats by enhancing autophagy via inhibiting the β-catenin/TCF4/GSK-3β/mTOR pathway

Keywords: هدف پستانداران رپامایسین; 1,25D3; 1,25-dihydroxyvitamin D3; VDR; vitamin D receptor; 25(OH)D; 25-dihydroxyvitamin D; DCM; diabetic cardiomyopathy; CQ; chloroquine; STZ; streptozotocin; lenti-shVDR; lentiviral vectors expressing a short hairpin RNA against VDR; TSC; tuberous sclero

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

Src-family tyrosine kinases and the Ca2 + signal

Keywords: هدف پستانداران رپامایسین; 5-HT6; serotonin receptor 6; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid; ADPR; ADP-ribose; AMPA; α-amino-3-hydr

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease

Keywords: هدف پستانداران رپامایسین; AD; Alzheimer's disease; AGC; protein kinase A/protein kinase G/protein kinase C; Akt; protein kinase B; ATG13; autophagy-related gene 13; Aβ; amyloid-beta; BDNF; brain-derived neurotrophic factor; CaMKII; Ca2+/calmodulin-dependent kinase II; cAMP; cyc

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs

Keywords: هدف پستانداران رپامایسین; LAT; L-type amino acid transporters 1; SLC; solute carrier; CD98; cluster of differentiation 98; ASCT2; AlaSerCys Transporter 2; mTOR; mammalian target of rapamycin; BBB; blood brain barrier; AdiC; l-arginine/agmatine antiporter; C12E8; octaethylene glyco

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2017 سفارش ترجمه

Sulforaphane inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation by targeting mTOR/p70S6kinase signaling independent of Nrf2 activation

Keywords: هدف پستانداران رپامایسین; Sulforaphane (PubChem CID: 5350); Dimethyl Sulfoxide (PubChem CID: 679); ARE; antioxidant response element; CREB; cAMP-response element-binding protein; DAB; diaminobenzidine; DMSO; dimethyl sulfoxide; 4E-BP1; eukaryotic translation initiation factor 4E-b

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of Klotho on fibrosis and cancer: A renal focus on mechanisms and therapeutic strategies

Keywords: هدف پستانداران رپامایسین; ACE; angiotensin converting enzyme; ADAM; a disintegrin and metalloproteinase; AKI; acute kidney injury; ANGII; angiotensin II; AT1; angiotensin II receptor type 1; AMPKα; AMP-activated protein kinase α; α-SMA; α-smooth muscle actin; CKD; chronic kidn

دانلود رایگان متن کامل مقاله ISI 82 صفحه سال انتشار : 2017 سفارش ترجمه

Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review

Keywords: هدف پستانداران رپامایسین; Aβ42; β-amyloid42; ABCA1; ATP-Binding Cassette Transporter A1; AD; Alzheimers disease; ADAM; AD-related disintegrin and metalloprotease; AICD; APP- intracellular domain; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ApoE; ApolipoproteinE;

دانلود رایگان متن کامل مقاله ISI 175 صفحه سال انتشار : 2017 سفارش ترجمه

Asociación lupus eritematoso sistémico y esclerosis tuberosa, un caso

Keywords: هدف پستانداران رپامایسین; Lupus eritematoso sistémico; Esclerosis tuberosa; Complejo diana de la rapamicina; Systemic lupus erithematosus; Tuberous sclerosis; Mammalian target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy in allografts rejection: A new direction?

Keywords: هدف پستانداران رپامایسین; Autophagy; Transplantation; Allograft; T lymphocyte; Tolerance; TCR; T cell receptor; I/R; Ischemia-reperfusion; PI3K; Phosphatidylinosito 3-kinase; mTOR; Mammalian target of rapamycin; CNI; Calcineurin inhibitor;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy is an important metabolic pathway to determine leukemia cell survival following suppression of the glycolytic pathway

Keywords: هدف پستانداران رپامایسین; Autophagy; Glycolysis; Oxidative phosphorylation; Pentose phosphate pathway; Leukemia cells; Cancer energy metabolism; 6-AN; 6-aminonicotinamide; CQ; chloroquine diphosphate; DMSO; dimethyl sulfoxide; HIF; hypoxia-inducible factor; mTOR; mammalian target

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Safety of Everolimus in Patients Younger than 3 Years of Age: Results from EXIST-1, a Randomized, Controlled Clinical Trial

Keywords: هدف پستانداران رپامایسین; AE; Adverse event; EXIST-1; EXamining everolimus In a Study of Tuberous Sclerosis Complex-1; mTOR; Mammalian target of rapamycin; SAE; Serious AE; SEGA; Subependymal giant cell astrocytoma; TSC; Tuberous sclerosis complex;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

FXR blocks the growth of liver cancer cells through inhibiting mTOR-s6K pathway

Keywords: هدف پستانداران رپامایسین; FXR; mTOR/S6K; Liver cancer cells; Proliferation; AP; Ammonium peroxydisulfate; Acr-Bis; Acrylamide-bisacrylamide; BCA; Bicinchoninic acid; BLAST; Basic Local Alignment Search Tool; BSA; Bovine serum albumin; DEPC; Diethypyrocarbonate; DMSO; Dimethyl sulf

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of the Let-7 Family MicroRNAs Induces Cardioprotection Against Ischemia-Reperfusion Injury in Diabetic Rats

Keywords: هدف پستانداران رپامایسین; AAR; area at risk; antimiR; antimicroRNA; C; control; DR; diabetic rat; GLUT4; glucose transporter type 4; IGF-1R; insulinlike growth factor-1 receptor; InsR; insulin receptor; IS; infarct size; L; lentivirus vectors with let-7 antimiR; LY; LY294002; miRN

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of mTOR improves the impairment of acidification in autophagic vesicles caused by hepatic steatosis

Keywords: هدف پستانداران رپامایسین; Autophagy; Lysosome; Vacuolar-ATPase; Rapamycin; Analysis of variance; ANOVA; mammalian target of rapamycin; mTOR; nonalcoholic fatty liver disease; NAFLD; nonalcoholic steatohepatitis; NASH; endoplasmic reticulum; ER; green fluorescent protein; GFP; micr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه