دانلود مقالات ISI درباره هدف پستانداران رپامایسین + ترجمه فارسی

Rapamycin-induced G1 cell cycle arrest employs both TGF-β and Rb pathways

Keywords: هدف پستانداران رپامایسین; mTOR; Rapamycin; Rb; TGF-β; eIF4E; 4E-BP1; eIF4E-binding protein-1; CDK; cyclin-dependent kinase; eIF4E; eukaryotic initiation factor 4E; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; S6K; S6 kinase; TGF-β; transforming growth factor-β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Systems biology of IL-6, IL-12 family cytokines

Keywords: هدف پستانداران رپامایسین; Systems biology; Mathematical modeling; IL-6-type cytokines; Quantitative analyses; Epo; erythropoietin; gp; glycoprotein; hESC; human embryonic stem cells; EGF; epidermal growth factor; ERK; extracellular signal regulated kinase; HGF; hepatocyte growth f

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Cell Cycle Regulation of Smooth Muscle Cells-Searching for Inhibitors of Neointima Formation: Is Combretastatin A4 an Alternative to Sirolimus and Paclitaxel?

Keywords: هدف پستانداران رپامایسین; CA4; combretastatin A4; CDK; cyclin-dependent kinase; CI; confidence interval; mTOR; mammalian target of rapamycin; PPARγ; peroxisome proliferator activated receptor γ; SMC; smooth muscle cell;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy

Keywords: هدف پستانداران رپامایسین; ULK1; UNC-51 like kinase; AMPK; Adenosine 5′-monophosphate (AMP)-activated protein kinase; FUNDC1; FUN-14 domain containing protein; mTOR; Mammalian target of rapamycin; LC3; Light chain 3; Mitophagy; UNC-51 like kinase; Adenosine 5′-monophosphate (AM

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells

Keywords: هدف پستانداران رپامایسین; PD; Platycodin D; CQ; chloroquine; DMSO; dimethylsulfoxide; MTT; 3-[4,5-Dimethyl-2-thiazolyl]-2,5-diphenyltetrazolium bromide; MDC; monodansylcadaverin; ERK; extracellular signal-regulated kinase; BAF; bafilomycin A1; LC3; microtubule-associated protein 1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

A treadmill exercise reactivates the signaling of the mammalian target of rapamycin (mTor) in the skeletal muscles of starved mice

Keywords: هدف پستانداران رپامایسین; mTor; mammalian target of rapamycin; GFP; green fluorescent protein; LC3; microtubule-associated protein IA/IB light chain 3; IGF-1; insulin-like growth factor 1; Autophagy; Exercise; Treadmill; Skeletal muscle; mTor; GFP-LC3;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Citreoviridin induces ROS-dependent autophagic cell death in human liver HepG2 cells

Keywords: هدف پستانداران رپامایسین; Citreoviridin; Autophagy; Reactive oxygen species; Human liver HepG2 cells; CIT; citreoviridin; ROS; reactive oxygen species; NAC; N-acetyl cysteine; 3-MA; 3-methyladenine; MTT; 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide; LC50; median

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of the insulin-like growth factor 1 receptor by CHM-1 blocks proliferation of glioblastoma multiforme cells

Keywords: هدف پستانداران رپامایسین; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth factor receptor; GBM; glioblastoma multiforme; IGF-1R; insulin-like growth factor-1 receptor; IR; insulin receptor; PDGFR; platelet-derived growth factor receptor; PI3K; phosphatidylinositol

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Yeast-based methods to assess PTEN phosphoinositide phosphatase activity in vivo

Keywords: هدف پستانداران رپامایسین; CWI; cell wall integrity; Gal; galactose; MAPK; mitogen-activated protein kinase; mTOR; mammalian target of rapamycin; PDK1; phosphoinositide-dependent kinase; PH; pleckstrin homology; PI3K; phosphoinositide 3-kinase; PtdIns(4,5)P2; phosphatidylinositol (

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Sphingosylphosphorylcholine protects cardiomyocytes against ischemic apoptosis via lipid raft/PTEN/Akt1/mTOR mediated autophagy

Keywords: هدف پستانداران رپامایسین; SPC; sphingosylphosphorylcholine; I/R; ischemia/reperfusion; MTOR; mammalian target of rapamycin; MTORC1; mTOR complex 1; MTORC2; mTOR complex 2; MI; myocardial infarction; PI3K; phosphatidylinositol 3-kinase; TSC2; tuberous sclerosis complex 2; HUVECs; h

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Noncoding RNAs as regulators of cardiomyocyte proliferation and death

Keywords: هدف پستانداران رپامایسین; miRNAs; microRNAs; lncRNA; long non-coding RNA; LAD; left anterior descending coronary artery; hCMPCs; human Cardiomyocyte Progenitor Cells; CSCs; Cardiac Stem Cells; MI; Myocardial Infarction; MFN1; Mitofusin 1; I/R; Ischemia/Reperfusion; BNIP3; BCL2/ade

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Ciliary neurotrophic factor (CNTF): New facets of an old molecule for treating neurodegenerative and metabolic syndrome pathologies

Keywords: هدف پستانداران رپامایسین; CNTF; ciliary neurotrophic factor; CNTFR; ciliary neurotrophic factor receptor; LIFR; leukemia inhibitor factor receptor; gp130; glycoprotein-130; IL6; Interleukin-6; IFNγ; interferon gamma; JAK; Janus kinases; STAT; signal transducers and activators of

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNAs in osteosarcoma

Keywords: هدف پستانداران رپامایسین; OS; osteosarcoma; miRNAs; microRNAs; CSCs; cancer stem cells; RNA pol; RNA polymerase; DGCR8; DiGeorge syndrome critical gene 8; RISC; RNA-induced silencing complex; Exp 5; exportin 5; Ago; argonaute; MREs; miRNA recognition elements; APE1; apurinic/apyri

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

A structural insight into the inhibitory mechanism of an orally active PI3K/mTOR dual inhibitor, PKI-179 using computational approaches

Keywords: هدف پستانداران رپامایسین; PI3K; phosphatidylinositide 3-kinase; PIP2; phosphatidylinositol-4,5-bisphosphate; PIP3; phosphatidylinositol-3,4,5-trisphosphate; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; ASA; accessible surface area; ΔASA; lo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanistic Target of Rapamycin (mTOR) in Tuberous Sclerosis Complex-Associated Epilepsy

Keywords: هدف پستانداران رپامایسین; mTOR inhibitor; tuberous sclerosis complex; epilepsy; epileptogenesis; mechanistic target of rapamycin; mammalian target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Paracrine co-delivery of TGF-β and IL-2 using CD4-targeted nanoparticles for induction and maintenance of regulatory T cells

Keywords: هدف پستانداران رپامایسین; Autoimmunity; Drug delivery; Immunomodulation; Nanoparticles; TGF-β; Interleukin-2; CD; cluster of differentiation; DMSO; dimethylsulfoxide; ELISA; enzyme-linked immunosorbent assay; FACS; fluorescent activated cell sorting; FBS; fetal bovine serum; GFP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Recherche translationnelle : médecine personnalisée, médecine de précision, thérapies ciblées : marketing ou science ?

Keywords: هدف پستانداران رپامایسین; médecine personnalisée; médecine stratifiée; biomarqueurs; test diagnostique compagnon; suivi thérapeutique pharmacologique; pharmacogénétique; ACP; anatomie et cytologie pathologique; ADN; acide désoxyribonucléique; AMM; autorisation de mise sur

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Zinc promotes proliferation and activation of myogenic cells via the PI3K/Akt and ERK signaling cascade

Keywords: هدف پستانداران رپامایسین; IR; insulin receptor; IGFR; insulin-like growth factor receptor; IRS-1; insulin receptor substrate-1; PI3K; phosphoinositide 3-kinase; mTOR; mammalian target of rapamycin; Grb2; growth factor receptor-bound protein 2; FGF2; fibroblast growth factor 2; DTP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Activated AMPK boosts the Nrf2/HO-1 signaling axis-A role for the unfolded protein response

Keywords: هدف پستانداران رپامایسین; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated kinase; ARE; antioxidant response element; βTrcP1; β-transducin-repeat containing protein 1; CaMKK; calcium calmodulin-dependent kinase kinase; CHO; Chinese hamster ovary; DCF; dichlorofluorescein; DMSO;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of mTOR pathway restrains astrocyte proliferation, migration and production of inflammatory mediators after oxygen-glucose deprivation and reoxygenation

Keywords: هدف پستانداران رپامایسین; Mammalian target of rapamycin; Reactive astrogliosis; Oxygen-glucose deprivation; Proliferation; Migration; Inflammation mediator; EdU; 5-ethynyl-29-deoxyuridine; mTOR; mammalian target of rapamycin; p-mTOR; phosphorylated mammalian target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-7: A miRNA with expanding roles in development and disease

Keywords: هدف پستانداران رپامایسین; ACK1; activated CDC42 kinase 1; BASP1; brain abundant, membrane attached signal protein 1; c-Myc; v-Myc avian myelocytomatosis viral oncogene homolog; CD57; cluster of differentiation 57; CD44; cluster of differentiation 44; ciRS-7; circular RNA sponge fo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Metformin inhibits age-related centrosome amplification in Drosophila midgut stem cells through AKT/TOR pathway

Keywords: هدف پستانداران رپامایسین; 4E-BP; eukaryotic translation initiation factor 4E-binding protein; 8-oxo-dG; 8-oxo-2′-deoxyguanosine; AMPK; 5′ AMP-activated protein kinase; EBs; enteroblasts; ECs; enterocytes; EEs; enteroendocrine cells; EGFR; epidermal growth factor receptor; IGF1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

PI3K/Akt signaling in osteosarcoma

Keywords: هدف پستانداران رپامایسین; OS; osteosarcoma; PI3K; phosphatidylinositol 3-kinase; PTEN; phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; RTKs; receptor tyrosine kinases; PDGFR; platelet-derived growth factor receptor; IGF1R; insulin-like growth factor 1 receptor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy

Keywords: هدف پستانداران رپامایسین; Actb; β-actin; AMPK; adenosine monophosphate protein kinase; Bgn; biglycan; CDK; cyclin-dependent kinase; Dcn; decorin; EGFR; epidermal growth factor receptor; GFP; green fluorescent protein; IGF-IR; insulin-like growth factor receptor I; LC3; microtubul

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Plasma membrane gp96 enhances invasion and metastatic potential of liver cancer via regulation of uPAR

Keywords: هدف پستانداران رپامایسین; mgp96; uPAR; Liver cancer; MAPK; DFS; ADAMTS9; a disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs 9; AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; AKT; v-akt murine thymoma viral oncogene homo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

Keywords: هدف پستانداران رپامایسین; Raptor; regulatory associated protein of mTOR; Rictor; rapamycin-insensitive companion of mTOR; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; m-TORC2; mTOR complex 2; Sp1; specific protein 1; MTH; mithramycin; RAPA; rapamycin; ChIP; chromat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells

Keywords: هدف پستانداران رپامایسین; ACO; aconitase; ASK1; apoptosis signal-regulating kinase 1; Bcl-2; B-cell lymphoma 2; CaM; calmodulin; CD95; cluster of differentiation 95; DTNB; 5,5-dithio-bis-2-nitrobenzoic acid; ELISA; enzyme-linked immunosorbent assay; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Cohesin modulates transcription of estrogen-responsive genes

Keywords: هدف پستانداران رپامایسین; ER; estrogen receptor alpha; ERE; estrogen response element; TAD; topologically associated domain; CdLS; Cornelia de Lange Syndrome; FOXA1; Forkhead Box A1; GATA3; GATA Binding Protein 3; ChIP; chromatin immunoprecipitation; ErbB; epidermal growth factor

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model

Keywords: هدف پستانداران رپامایسین; ALS; amyotrophic lateral sclerosis; fALS; familial ALS; HD; Huntington disease; HspB8; heat shock protein B8; LBHI; Lewy body-like inclusions; mTOR; mammalian target of rapamycin; PBS; phosphate-buffered saline; PD; Parkinson disease; SD; standard deviati

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

The integrated role of ACh, ERK and mTOR in the mechanisms of hippocampal inhibitory avoidance memory

Keywords: هدف پستانداران رپامایسین; 4E-BPs; 4E binding proteins; ACh; acetylcholine; AD; Alzheimer's Disease; APP; amyloid precursor protein; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CREB; cAMP response element-binding protein; DG; dentate gyrus; eEF1A; eukaryotic Elongation F

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Differential contribution of key metabolic substrates and cellular oxygen in HIF signalling

Keywords: هدف پستانداران رپامایسین; ACC; acetyl-CoA carboxylase; Akt; protein kinase B (PKB); α-KG; α-ketoglutarate; AMPK; AMP-activated protein kinase; BPTES; (bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide; DIC; differential interference contrast; DMEM; Dulbecco׳s Modifie

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition

Keywords: هدف پستانداران رپامایسین; Methylseleninic acid (PubChem CID: 161597); Sodium selenite (PubChem CID: 24934); Cisplatin (PubChem CID: 441203); LY294002 (PubChem CID: 3973); MSA; methylseleninic acid; Se; selenium; PPP; pentose phosphate pathway; TCA; tricarboxylic acid; ROS; reactiv

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs

Keywords: هدف پستانداران رپامایسین; 3MA; 3-methyladenine; Baf (or Baf A1); bafilomycin A1; BSA; bovine serum albumin; GABARAP; γ-aminobutyric acid receptor-associated protein; LC3; microtubule-associated protein 1 light chain 3; LDH; lactate dehydrogenase; MEFs; mouse embryonic fibroblasts

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of hippocampal synaptic plasticity by BDNF

Keywords: هدف پستانداران رپامایسین; 4E-BPs; eIF4E-binding proteins; 5-HT; 5-hydroxytryptamine; ADF; actin-depolymerising factor; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptors; Arc; activity-regulated cytoskeleton-associated protein; BDNF; brain-derived n

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR-YY1-PGC1α pathway

Keywords: هدف پستانداران رپامایسین; CS; citrate synthase; ECAR; extracellular acidification rate; FGF21; fibroblast growth factor; MELAS; mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes; mtDNA; mitochondrial DNA; mTOR; mammalian target of rapamycin; mTORC; mTOR co

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

The hippocampus and TNF: Common links between chronic pain and depression

Keywords: هدف پستانداران رپامایسین; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid; AR; adrenergic receptor; BDNF; brain-derived neurotrophic factor; CNS; central nervous system; CREB; cAMP response element-binding protein; cAMP; cyclic adenosine monophosphate; ERK; extracellu

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

The role of autophagic degradation in the heart

Keywords: هدف پستانداران رپامایسین; αMHC-Cre+; transgenic mice expressing Cre recombinase under the control of α-myosin heavy chain promoter; Ambra1; activating molecule in Beclin 1-regulated autophagy; AMPK; AMP-activated protein kinase; Atg; autophagy-related; Bcl; B-cell lymphoma; Bnip

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting strategies on miRNA-21 and PDCD4 for glioblastoma

Keywords: هدف پستانداران رپامایسین; GBM; glioblastoma multiforme; miRNAs; microRNAs; PDCD4; programmed cell death 4; EMT; epithelial-mesenchymal transition; JNK; Jun N-terminal protein kinase; PTEN; phosphatase and tensin homolog; PI3K/AKT; phosphatidylinositol-3 kinase/Akt; MAPK/ERK; mit

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs

Keywords: هدف پستانداران رپامایسین; Mango; Breast cancer; Xenograft; PI3K/AKT; miR-126; GAE; gallic acid equivalent; HIF-1α; hypoxia inducible factor-1α; MS; mass spectrometry; mTOR; mammalian target of rapamycin; NF-κB; nuclear factor-kappa B; PI3K; phosphoinositide 3-kinase; VEGF;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

SH2 domain-containing inositol 5-phosphatase (SHIP2) inhibition ameliorates high glucose-induced de-novo lipogenesis and VLDL production through regulating AMPK/mTOR/SREBP1 pathway and ROS production in HepG2 cells

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated protein kinase; ACC; Acyl COA Carboxylase; BSA; Bovine Serum Albumin; DHE; Dihydroethidium; DPI; Diphenylene iodonium; ERK; Extracellular signal-regulated kinase; FAS; Fatty Acid Synthase; FBS; Fetal bovine serum; FOXO1; Forkhead box p

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2015 سفارش ترجمه

Redox modulation of mitochondriogenesis in exercise. Does antioxidant supplementation blunt the benefits of exercise training?

Keywords: هدف پستانداران رپامایسین; Akt; protein kinase B; AMPK; 5′-AMP-activated protein kinase; AP-1; activator protein 1; COX IV; cytochrome c oxidase; CuZnSOD; copper/zinc superoxide dismutase; DMSO; dimethyl sulfoxide; eNOS; endothelial nitric oxide synthase; ERK; extracellular signa

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2015 سفارش ترجمه

SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated protein kinase; AKT; v-akt murine thymoma viral oncogene homolog; Atg; autophagy-related gene; CAY; CAY-10566; CC; compound C; CQ; chloroquine; DAB; 3,3′-diaminobenzidine tetrahydrochloride; ECL; electrochemiluminescence; FBS; fetal

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

The MANDELA study: A multicenter, randomized, open-label, parallel group trial to refine the use of everolimus after heart transplantation

Keywords: هدف پستانداران رپامایسین; BPAR; biopsy-proven acute rejection; CAV; cardiac allograft vasculopathy; CMV; cytomegalovirus; CNI; calcineurin inhibitor; CsA; cyclosporine; eGFR; estimated glomerular filtration rate; IVUS; intravascular ultrasound; LVAD; left ventricular assist device

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy in neurodegenerative diseases: From pathogenic dysfunction to therapeutic modulation

Keywords: هدف پستانداران رپامایسین; Aβ; amyloid beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; ATP; adenosine triphosphate; Bci3; Bax cannel inhibitor 3; cAMP; cyclic adenosine monophosphate; CMA; chaperone-mediated autophagy; DLB; dement

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

MYC and metabolism on the path to cancer

Keywords: هدف پستانداران رپامایسین; 2-DG; 2-deoxyglucose; 4E-BP; eIF4E-binding protein; 5,10-methylene THF; 5,10-methylenetetrahydrofolate; ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ChIP-seq; chromatin immunoprecip

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

PIM kinase (and Akt) biology and signaling in tumors

Keywords: هدف پستانداران رپامایسین; PIM kinases; Akt; Oncogenes; Cancer; Therapeutic resistance; AML; acute myeloid leukemia; AMPK; AMP activated protein kinase; CXCR-4; C-X-C chemokine receptor type 4; EGFR; epidermal growth factor receptor; EBV; Epstein-Barr virus; FLT3; FMS-like ty

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease

Keywords: هدف پستانداران رپامایسین; A; adult; AET; aerobic exercise training; AUC; area under the curve; CI-MPR; cation-independent mannose-6-phosphate receptor; CLEAR; coordinated lysosomal expression and regulation transcriptome; ERT; enzyme replacement therapy; FA; fatty acid; FG; fast-t

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2015 سفارش ترجمه

Chromosome-Associated Protein D3 Promotes Bacterial Clearance in Human Intestinal Epithelial Cells by Repressing Expression of Amino Acid Transporters

Keywords: هدف پستانداران رپامایسین; Condensin; Inflammatory Bowel Disease; Innate Immunity; Dysbiosis; AIEC; adherent-invasive Escherichia coli; BCH; 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid; dCAP-D3; Drosophila chromosome-associated protein-D3; CAP-D3; human chromosome associated p

دانلود رایگان متن کامل مقاله ISI 2460 صفحه سال انتشار : 2015 سفارش ترجمه

Peroxisome proliferator activated receptor gamma (PPARγ) as a therapeutic target for improvement of cognitive performance in Fragile-X

Keywords: هدف پستانداران رپامایسین; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; CNS; central nervous system; ECM; extra cellular matrix; FMR1 gene; Fragile X mental retardation 1 gene; FMRP; Fragile-X mental retardation protein; FXS; Fragile X syndrome; GLUT-3; gl

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of novel 7-amino-5-methyl-1,6-naphthyridin-2(1H)-one derivatives as potent PI3K/mTOR dual inhibitors

Keywords: هدف پستانداران رپامایسین; Phosphoinositide 3-kinase; Mammalian target of rapamycin; Dual inhibitor; Anti-tumor activity;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه