دانلود مقالات ISI درباره هدف پستانداران رپامایسین + ترجمه فارسی

STAT signaling in different breast cancer sub-types

Keywords: هدف پستانداران رپامایسین; STAT; Signal Transducer and Activator of Transcription; ER; Estrogen Receptor; HER2; human epidermal growth factor 2; TNBC; Triple Negative Breast Cancer; IL; interleukin; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; JAK; Janu

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Alpha-melanocyte stimulating hormone protects retinal pigment epithelium cells from oxidative stress through activation of melanocortin 1 receptor-Akt-mTOR signaling

Keywords: هدف پستانداران رپامایسین; AMD; age-related macular degeneration; RPE; retinal pigment epithelium; α-MSH; α-melanocyte stimulating hormone; mTOR; mammalian target of rapamycin; MC1R; melanocortin 1 receptor; H2O2; hydrogen peroxide; Age related macular degeneration (AMD); Retinal

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The novel mTORC1/2 dual inhibitor INK-128 suppresses survival and proliferation of primary and transformed human pancreatic cancer cells

Keywords: هدف پستانداران رپامایسین; MTT; 3-[4,5-Dimethylthylthiazol-2-yl]-2,5 diphenyltetrazolium bromide; FACS; fluorescence-activated cell sorting; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; 4E-BP1; 4E-binding protein; OD; optical density; IP; imm

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

microRNA-7: A tumor suppressor miRNA with therapeutic potential

Keywords: هدف پستانداران رپامایسین; ACK1; activated CDC42 kinase 1; Akt; V-Akt murine thymoma viral oncogene homolog; BCL-2; B-cell CLL/lymphoma 2; CCNE1; cyclin E1; ciRS-7; circular RNA sponge 7; c-Myc; V-Myc avian myelocytomatosis viral oncogene homolog; EGFR; epidermal growth factor rece

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR regulates the nucleoplasmic diffusion of Xrn2 under conditions of heat stress

Keywords: هدف پستانداران رپامایسین; Mammalian target of rapamycin; tRNA degradation; Xrn2; Heat stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling

Keywords: هدف پستانداران رپامایسین; ANOVA; analysis of variance; CUL7; Cullin7; CRL7; Cullin RING E3 ubiquitin ligase 7; FBXW8; F-box/WD repeat-containing protein 8; GLUT4; glucose transporter 4; HSP90; heat shock protein 90; IRS; insulin receptor substrate; IGF-1; insulin-like growth hormo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Transient increase in proteinuria, poly-ubiquitylated proteins and ER stress markers in podocyte-specific autophagy-deficient mice following unilateral nephrectomy

Keywords: هدف پستانداران رپامایسین; UNX; unilateral nephrectomy/uninephrectomy; GFP; green fluorescent protein; mTor; mammalian target of rapamycin; Autophagy; Atg7; Podocyte; Nephrectomy; Ubiquitin; ER stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Human cytomegalovirus latent infection alters the expression of cellular and viral microRNA

Keywords: هدف پستانداران رپامایسین; miRNAs; microRNAs; HCMV; human cytomegalovirus; THP-1; human monocytic leukemia cell line; nt; nucleotides; mRNAs; messenger RNAs; 3′ UTR; 3′ untranslated regions; AIDS; Acquired Immune Deficiency Syndrome; HSV-1; herpes simplex virus 1; LATs; latency

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

DNA topoisomerases in mtDNA maintenance and ageing

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-dependent protein kinase; AMPKα2; alpha-subunit of AMP-dependent protein kinase; MEFs; Murine embryonic fibroblasts; mtDNA; mitochondrial DNA; mTOR; Mammalian target of rapamycin; ROS; Reactive oxygen species; TFAM; Mitochondrial transcription

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory effect of 14,15-EET on endothelial senescence through activation of mTOR complex 2/Akt signaling pathways

Keywords: هدف پستانداران رپامایسین; EETs; epoxyeicosatrienoic acids; eNOS; endothelial nitric oxide synthase; mTOR; mammalian target of rapamycin; mTORC2; mTOR complex 2; RMAECs; rat mesenteric arterial endothelial cells; rTERT; rat telomerase reverse transcriptase; SA-β-gal; senescence-as

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

GABARBP down-regulates HIF-1α expression through the VEGFR-2 and PI3K/mTOR/4E-BP1 pathways

Keywords: هدف پستانداران رپامایسین; GABARBP; human γ-aminobutyrate type A (GABAA) receptor-binding protein; VEGF; vascular endothelial growth factor; HIF-1α; hypoxia-inducible factor-1α; PDK1; phosphoinositide-dependent protein kinase-1; mTOR; mammalian target of rapamycin; TSC-2; tubero

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

Keywords: هدف پستانداران رپامایسین; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; ATP; adenosine triphosphate; Aβ; amyloid β peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; AMP; adenos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

mTORC1 signaling controls multiple steps in ribosome biogenesis

Keywords: هدف پستانداران رپامایسین; 4E-BP; eIF4E-binding protein; 5′-TOP; 5′-terminal oligopyrimidine tract; BOP1; block of proliferation 1; eEF2; eukaryotic elongation factor; eEF2K; eEF2 kinase; eIF; eukaryotic initiation factor; ERK; extracellular ligand-regulated kinase; MEK; MAP an

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Correlation and functional differentiation between different markers to study the genetic diversity analysis in medicinally important plant Plumbago zeylanica

Keywords: هدف پستانداران رپامایسین; Plumbago zeylanica; Genetic diversity; Phylogenetic analysis; SSR; SRAP; ITS; AFLP:; Amplified Fragment Length Polymorphism; AMOVA:; Analysis of molecular variance; ARE:; Antioxidant responsive element; CTAB:; Cetyl trimethylammonium bromide; dNTPs:; Deox

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by pharmacogenomics and molecular docking

Keywords: هدف پستانداران رپامایسین; ABC; ATP-binding cassette; Akt; v-Akt murine thymoma viral oncogene homolog 1; BCRP; breast cancer resistance protein; EGFR; epidermal growth factor; MAPK; mitogen-activated protein kinase; MDR; multidrug resistance; mTOR; mammalian target of rapamycin; P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Sulforaphane-induced autophagy flux prevents prion protein-mediated neurotoxicity through AMPK pathway

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated protein kinase; ATG5; autophagy-related 5; EDTA; ethylenediaminetetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; LDH; lactate dehydrogenase; mTOR; mammalian target of rapamycin; PI; propidium iodide; PrP; pr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

T cell receptor-mediated activation is a potent inducer of macroautophagy in human CD8+CD28+ T cells but not in CD8+CD28− T cells

Keywords: هدف پستانداران رپامایسین; mTOR; mammalian target of rapamycin; mTORC1/2; mTOR complex 1/2; TCR; T cell receptor; CMV; cytomegalovirus; PI3K; phosphoinositide 3-kinase; PKB; protein kinase B; PDK; phosphoinositide-dependent protein kinase 1; S6K1; S6 kinase 1; 4E-BP1; 4E-binding pr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

MTOR-independent induction of autophagy in trabecular meshwork cells subjected to biaxial stretch

Keywords: هدف پستانداران رپامایسین; TM; trabecular meshwork; IOP; intraocular pressure; ATG; autophagy-related genes; CTSB; cathepsin B; BECN1; beclin; TUBB; beta tubulin; SQSTM; sequestosome; tfLC3; tandem fluorescence LC3; GFP; green fluorescence protein; RFP; red fluorescence protein; m.

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Lysyl oxidase-like 2 (LOXL2) controls tumor-associated cell proliferation through the interaction with MARCKSL1

Keywords: هدف پستانداران رپامایسین; LOXL2; lysyl oxidase-like 2; MARCKSL1; myristoylated alanine-rich C kinase substrate-like 1; EMT; epithelial-mesenchymal transition; ECM; extracellular matrix; FAK; focal adhesion kinase; PKC; protein kinase C; siRNA; small interfering RNA; ONPG; o-nitr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Subchronic toxicity study of β-hydroxy-β-methylbutyric free acid in Sprague-Dawley rats

Keywords: هدف پستانداران رپامایسین; A/G ratio; albumin to globulin ratio; ALT; alanine aminotransferase; ANOVA; analysis of variance; AST; aspartate aminotransferase; CaHMB; calcium β-hydroxy-β-methylbutyrate-monohydrate; FDA; Food and Drug Administration; GGT; gamma-glutamyltransferase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Post-transcriptional regulation of autophagy in C2C12 myotubes following starvation and nutrient restoration

Keywords: هدف پستانداران رپامایسین; ACC; acetyl-CoA carboxylase; Akt/PKB; protein kinase B; AMPK; AMP-activated protein kinase; ANOVA; analysis of variance; Atg; autophagy-related gene; Bnip3; B-cell lymphoma 2 interacting protein 3; DMEM; Dulbecco's modified Eagle medium; DPBS; Dulbecco's

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

Keywords: هدف پستانداران رپامایسین; SLRP; small leucine-rich proteoglycan; RTK; receptor tyrosine kinase; HUVEC; human umbilical vein endothelial cells; Peg3; paternally expressed gene 3; AMPK; 5′ adenosine monophosphate-activated protein kinase; mTOR; mammalian target of rapamycin; Vps34

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

Keywords: هدف پستانداران رپامایسین; SLRP; small leucine-rich proteoglycan; RTK; receptor tyrosine kinase; HUVEC; human umbilical vein endothelial cells; Peg3; paternally expressed gene 3; AMPK; 5′ adenosine monophosphate-activated protein kinase; mTOR; mammalian target of rapamycin; Vps34

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

p70S6 kinase is a critical node that integrates HER-family and PI3 kinase signaling networks

Keywords: هدف پستانداران رپامایسین; p70S6K; p70S6 kinase; PI3K; phosphoinositide-3-kinase; RPPA; Reverse Phase Protein Array; mTOR; mammalian target of rapamycin; MAPK; mitogen activated protein kinase; EGFR; epidermal growth factor receptor; NSCLC; non-small cell lung cancer; RTK; receptor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease

Keywords: هدف پستانداران رپامایسین; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; 6-OHDA; 6-hydroxydopamine; ACC; acetyl-CoA carboxylase; AD; Alzheimer's disease; AMPK; AMP-dependent/activated protein kinase; DAB; 3,3′-diaminobenzidine tetrachloride; DAPI; 4′,6-diamidino-2-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca2 +-permeable AMPA receptors

Keywords: هدف پستانداران رپامایسین; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AP5; 2-amino-5-phosphonopentanoate; AMPK; 5′ AMP-activated protein kinase; AIF; apoptosis-inducing factor; Cyt-C; cytochrome-C; JNK; Jun N-terminal kinase; GluA1; glutamate AMPA receptor subun

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

FOXO1-dependent up-regulation of MAP kinase phosphatase 3 (MKP-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice

Keywords: هدف پستانداران رپامایسین; MKP-3; MAP kinase phosphatase 3; Dex; Dexamethasone; FOXO1; forkhead box protein O1; GC; glucocorticoid; DUSP6; dual specificity protein phosphatase 6; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; PI3K; phosphoinosit

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

In vivo hyperoxia induces hypoxia-inducible factor-1α overexpression in LNCaP tumors without affecting the tumor growth rate

Keywords: هدف پستانداران رپامایسین; In vivo hypoxia; In vivo hyperoxia; LNCaP tumor; Angiogenesis; Hypoxia-inducible factor; Akt; phosphatidylinositol-3-phosphate/protein kinase B; Hb; hemoglobin; HIF-1α; hypoxia-inducible factor-1α; Ki67; Antigen anti-KI-67; LNCaP; androgen-sensitive hum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells

Keywords: هدف پستانداران رپامایسین; T-ALL; GLI1; GANT58; AKT inhibitor; Apoptosis; Hh; hedgehog; T-ALL; acute T cell leukemia; SMO; Smoothened; GLI1; GLI family zinc finger 1; SHH; Sonic hedgehog; DHH; Desert hedgehog; IHH; Indian hedgehog; PTCH1; Patched 1; PI3K; phosphatidylinositol 3-kin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of mTOR down-regulates scavenger receptor, class B, type I (SR-BI) expression, reduces endothelial cell migration and impairs nitric oxide production

Keywords: هدف پستانداران رپامایسین; ABCG1; ATP binding cassette transporter G1; BP-C; Bodipy-cholesterol; BP-CE; Bodipy-cholesteryl oleate; CETP; cholesteryl ester transfer protein; DAF-2 DA; 4,5-diaminofluorescein diacetate; DiI; 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Inadequate mito-biogenesis in primary dermal fibroblasts from old humans is associated with impairment of PGC1A-independent stimulation

Keywords: هدف پستانداران رپامایسین; 12S; mitochondrial rRNA; AICAR; aminoimidazole-4-carboxamide riboside, an adenosine analogue stimulating AMPK; AMPK; catalytic α1/2-subunit of AMP dependent protein kinase; pAMPK; AMPK phosphorylated at serine 172 of the α-subunit; AU; arbitrary units;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Insulin-sensitizing and insulin-mimetic activities of Sarcopoterium spinosum extract

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated protein kinase; BAD; Bcl 2-antagonist of cell death; 2-DG; 2-deoxy-d-glucose; FoxO; forkhead transcription factor; GSK3β; glycogen synthase kinase 3β; IBMX; isobutylmethylxanthine; IKK; inhibitor of nuclear factor kappa-B kinase; IR;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Emerging strategies to overcome the resistance to current mTOR inhibitors in renal cell carcinoma

Keywords: هدف پستانداران رپامایسین; Autophagy; Clinical trials; Drug resistance; Mammalian target of rapamycin; mTOR inhibitors; Renal cell carcinoma;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells

Keywords: هدف پستانداران رپامایسین; TnTs; Tunneling nanotubes; nm; nanometers; (ATCC); American Type Culture Collection; FBS; fetal bovine serum; MAPK; mitogen-activated protein kinase; AMPK; adenosine monophosphate kinase; mTOR; mammalian target of rapamycin; CTCF; corrected total cell flu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Synuclein gamma protects HER2 and renders resistance to Hsp90 disruption

Keywords: هدف پستانداران رپامایسین; Synuclein gamma; Chaperone; HER2 signaling; Breast cancer; Therapy resistance; BCSG1; breast cancer specific gene 1; ERα; estrogen receptor α; Hsp; heat shock protein; mTOR; mammalian target of rapamycin; SNCA; synuclein α; SNCB; synuclein β; SNCG; sy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

WIF1 can effectively co-regulate pro-apoptotic activity through the combination with DKK1

Keywords: هدف پستانداران رپامایسین; WIF1; Wnt inhibitory factor-1; Dvl; disheveled; FRP; Frizzled-related protein; DKK1; Dickkopf-1; VEGF; vascular endothelial growth factor; bFGF; basic fibroblast growth factor; FITC; fluorescein isothiocyanate; PI; propidium iodide; p70S6K; p70 ribosomal

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The PPARβ agonist L-165041 promotes VEGF mRNA stabilization in HPV18-harboring HeLa cells through a receptor-independent mechanism

Keywords: هدف پستانداران رپامایسین; ARE; AU-rich element; CHX; cycloheximide; ELAV; Embryonic Lethal Abnormal Vision; ERK1/2; Extracellular signal Regulated Kinase1/2; HPV; Human Papillomavirus; HuR; Human antigen R; MAPK; Mitogen-Activated Protein Kinase; mTOR; mammalian Target Of Rapamyci

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

LXR-α antagonist meso-dihydroguaiaretic acid attenuates high-fat diet-induced nonalcoholic fatty liver

Keywords: هدف پستانداران رپامایسین; ABCA1, ABCG1; ATP-binding cassette transporter A1 or G1; AMPK; AMP-activated protein kinase; ACC; acetyl-coenzyme A carboxylase; FAS; fatty acid synthase; HDL; high density lipoprotein; HFD; high fat diet; LBD; ligand binding domain; LXR; liver X receptor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The links between AKT and two intracellular proteolytic cascades: Ubiquitination and autophagy

Keywords: هدف پستانداران رپامایسین; BRCA1; breast cancer susceptibility gene 1; BRCT; Brca1 C-terminal; CHIP; chaperone-associated ubiquitin ligase; CYLD; cylindromatosis; DAPK; death-associated protein kinase; DUB; deubiquitinating enzyme); EGF; epidermal growth factor; FADD; fas-associate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Isoangustone A induces apoptosis in SW480 human colorectal adenocarcinoma cells by disrupting mitochondrial functions

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated protein kinase; BSA; bovine serum albumin; DCFH-DA; dichlorofluorescin diacetate; DR4; death receptor 4; ETC; electron transport chain; FBS; fetal bovine serum; HEGU; hexane/ethanol extract of Glycyrrhiza uralensis Fisch; IAA; isoangus

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Necessary, but not sufficient: Insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures

Keywords: هدف پستانداران رپامایسین; Early life seizure; Long-term depression; Metabotropic glutamate receptor; CaMKII; Voltage-gated calcium channels; Autism; ACSF; artificial cerebral spinal fluid; APV; amino-5-phosphonopentanoic acid; CaMKII; calcium-calmodulin kinase II; DMSO; dimethyl s

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia

Keywords: هدف پستانداران رپامایسین; ADAM; a disintegrin and metalloprotease; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AKT; protein kinase B (PKB); ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AMPK; adenosine monophosphate (AMP) activated protein kinase; ANK;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

BDNF mechanisms in late LTP formation: A synthesis and breakdown

Keywords: هدف پستانداران رپامایسین; Brain-derived neurotrophic factor (BDNF); TrkB signaling; Synaptic plasticity; Long-term potentiation (LTP); Protein synthesis; Translation control; Cytoskeletal dynamics; Arc; activity-regulated cytoskeleton-associated protein; AS; Angelman syndrome; AS-

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Hippocampal subregion-specific microRNA expression during epileptogenesis in experimental temporal lobe epilepsy

Keywords: هدف پستانداران رپامایسین; miRNAs; microRNAs; DG; dentate gyrus; PHC; parahippocampal cortex; MAPK; mitogen-activated protein kinase; TGFβ; transforming growth factor beta; mTOR; mammalian target of rapamycin; TLE; temporal lobe epilepsy; SE; status epilepticus; RIN; RNA Integrity

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

IL-27 inhibits IFN-γ induced autophagy by concomitant induction of JAK/PI3 K/Akt/mTOR cascade and up-regulation of Mcl-1 in Mycobacterium tuberculosis H37Rv infected macrophages

Keywords: هدف پستانداران رپامایسین; Autophagy; IFN-γ; IL-27; Mycobacteria; mTOR; mammalian target of rapamycin; PI3 K; phosphatidylinositol 3-kinase; JAK; Janus kinase;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Prevention of BMS-777607-induced polyploidy/senescence by mTOR inhibitor AZD8055 sensitizes breast cancer cells to cytotoxic chemotherapeutics

Keywords: هدف پستانداران رپامایسین; Breast cancer; Receptor tyrosine kinase; Small molecule inhibitor; Senescence; Polyploidy; mTOR signaling; Chemosensitivity; AXL; Greek word anexelekto; BCR; breakpoint cluster region; BRAF; B-Rapidly Accelerated Fibrosarcoma; DAPI; 4′,6′-diamidino-2-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Human DExD/H RNA helicases: Emerging roles in stress survival regulation

Keywords: هدف پستانداران رپامایسین; 5′ppp; 5′ triphosphate; AMD; ARE-mediated mRNA decay; ARE; AU-rich element; ARE-BP; ARE-binding protein; CARD; caspase activation and recruitment domain; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; CDN; cyclic dinucleotide; CRM1; Chromosome Maint

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

BDNF-induced local protein synthesis and synaptic plasticity

Keywords: هدف پستانداران رپامایسین; Brain-derived neurotrophic factor (BDNF); Synaptic plasticity; Long-term potentiation (LTP); Translation; RNA transport; ADF; actin-depolymerizing factor; A2RE; heterogeneous nuclear ribonucleoprotein (hnRNP) A2 response element; Arc; activity-regulated c

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Ribonucleoprotein HNRNPA2B1 Interacts With and Regulates Oncogenic KRAS in Pancreatic Ductal Adenocarcinoma Cells

Keywords: هدف پستانداران رپامایسین; Signal Transduction; Carcinogenesis; Oncogene; Mouse Model; AKT; c-akt murine thymoma oncogene homolog 1; FCS; fetal calf serum; GFP; green fluorescent protein; GTP; guanosine triphosphate; HA; hemagglutinin; hnRNP; heterogeneous nuclear ribonucleoprotein

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Neurogenesis in neurological and psychiatric diseases and brain injury: From bench to bedside

Keywords: هدف پستانداران رپامایسین; 6-OHDA; 6-hydroxydopamine; 7-OH-DPAT; 7-hydroxy-N,N-di-n-propyl-2-aminotetralin; AD; Alzheimer's disease; ADAM; a disintegrin and metalloproteinase; APH-1; anterior pharynx-defective 1; ApoE4; apolipoprotein E ɛ4 allele; APP; amyloid precursor protein; A

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه