دانلود مقالات ISI درباره هدف پستانداران رپامایسین + ترجمه فارسی

PARP and other prospective targets for poisoning cancer cell metabolism

Keywords: هدف پستانداران رپامایسین; ATP; adenosine 5′-triphosphate; 3-BrPA; 3-bromopyruvate; EGFR; epidermal growth factor receptor; FDA; food and drug administration; GSH; glutathione; GSSG; oxidized GSH; GST; glutathione S-transferase; HDAC; histone deacetylase; HIF1; hypoxia inducible

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells

Keywords: هدف پستانداران رپامایسین; CRC; colorectal cancer; CPT; camptothecin; DSBs; double-strand breaks; DDR; DNA damage response; γ-H2AX; phosphorylated histone H2AX; ATM; ataxia telangiectasia mutated; Chk2; check-point kinase; AMPK; AMP-activated protein kinase; TSC2; tuberous scleros

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

Keywords: هدف پستانداران رپامایسین; PI3K pathway; Targeted therapy; Predictive biomarkers; 4EBP1; 4E-binding protein 1; AKT; protein kinase-B; AMPK; AMP-activated protein kinase; COSMIC; Catalogue of Somatic Mutations in Cancer; eIF4E; eukaryotic initiation factor 4E; ERK; extracellular-sig

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2014 سفارش ترجمه

Increased mTORC1 activity contributes to atherosclerosis in apolipoprotein E knockout mice and in vascular smooth muscle cells

Keywords: هدف پستانداران رپامایسین; Inflammation; Mammalian target of rapamycin; LDL receptor pathway; Atherosclerosis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate

Keywords: هدف پستانداران رپامایسین; AML; acute myeloid leukemia; RTP; ribavirin triphosphate; mTOR; mammalian target of rapamycin; CD; circular dichroism; m7G; 7-methyl-guanosine; m7GTP; 7-methyl-guanosine-5′-triphosphate; HSQC; heteronuclear single quantum coherence; RING; really interes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Differential anti-tumor activities of curcumin against Ras- and Src-activated human adenocarcinoma cells

Keywords: هدف پستانداران رپامایسین; 4E-BP1; eukaryotic initiation factor 4-binding protein 1; Cdk1; cyclin-dependent kinase 1; EGFR; epidermal growth factor receptor; FACS; fluorescence activated cell sorting; IC50; 50% inhibitory concentration; MAPK; mitogen-activated protein kinase; mTOR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacological inhibition of the mTOR pathway impairs hippocampal development in mice

Keywords: هدف پستانداران رپامایسین; BrdU; 5-bromo-2-deoxyuridine; DCX; doublecortin; DG; dentate gyrus; GFP; green fluorescent protein; GS; glutamine synthetase; Iba1; ionized calcium binding adaptor molecule 1; mTOR; mammalian target of rapamycin; Neu N; neuronal nuclei; Dentate gyrus; Neu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Everolimus in hormone receptor-positive advanced breast cancer: Targeting receptor-based mechanisms of resistance

Keywords: هدف پستانداران رپامایسین; Estrogen receptor; Mammalian target of rapamycin; mTOR; Everolimus;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Vasopressin activates Akt/mTOR pathway in smooth muscle cells cultured in high glucose concentration

Keywords: هدف پستانداران رپامایسین; AVP; arginine vasopressin; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; PI3K; phosphatidyl inositol-3 kinase; AMPK; AMP-activated protein kinase; PKC; protein kinase C, Akt or protein kinase B; TSC1/TSC2; tubero sclerosis protein 1 and 2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Clinical evaluation of the endothelial tie-2 crossmatch in ABO compatible and ABO incompatible renal transplants

Keywords: هدف پستانداران رپامایسین; ADCC; antibody dependent cell cytotoxicity; EC; endothelial cell; PEC; precursor endothelial cell; RTx; renal transplantation; IS; immunosuppression; MPA; mycophenolate acid; mTORi; mammalian target of rapamycin; PP; plasmapharesis; IVIg; intravenous immu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Insulin receptor substrate-1 (IRS-1) forms a ribonucleoprotein complex associated with polysomes

Keywords: هدف پستانداران رپامایسین; IRSs; insulin receptor substrates; IGFs; insulin-like growth factors; PABPC1; poly(A) binding protein cytoplasmic 1; MALDI-TOF-MS; matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry; BN-PAGE; blue native-polyacrylamide gel elec

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Steroid withdrawal and reduction of cyclosporine A under mycophenolate mofetil after heart transplantation

Keywords: هدف پستانداران رپامایسین; AE; adverse events; ANOVA; analysis of variance; AUC; area under curve; BMI; body mass index; BUN; blood urea nitrogen; CAV; chronic allograft vasculopathy; CNI; calcineurin inhibitors; CPET; cardiopulmonary exercise test; CRH; cortisol releasing hormone;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Pregnane alkaloids from Sarcococca hookeriana var. digyna

Keywords: هدف پستانداران رپامایسین; cAMP; cyclic adenosine monophosphate; PKA; protein kinase A; CREB; cAMP response element binding protein; PI3K; phosphatidylinositol-3 kinase; Akt; protein kinase B; mTOR; mammalian target of rapamycin; MAPK; mitogen-activated protein kinase; ERK; extrace

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Jurkat cell proliferation is suppressed by Chlamydia (Chlamydophila) pneumoniae infection accompanied with attenuation of phosphorylation at Thr389 of host cellular p70S6K

Keywords: هدف پستانداران رپامایسین; PBMC; peripheral blood mononuclear cell; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; LPS; lipopolysaccharide; HBSS; Hank's balanced salt solution; PI3K; mammalian target of rapamycin; mTOR; phosphoinositide 3-kinase; mTORC1; multi-component m

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Hypoxia reduces endothelial Ang1-induced Tie2 activity in a Tie1-dependent manner

Keywords: هدف پستانداران رپامایسین; Ang1; angiopoietin-1; DFX; desferrioxamine; HIF; hypoxia-inducible factor; HUVEC; human umbilical vein endothelial cell; mTOR; mammalian target of rapamycin; PI3K; phosphatidylinositol 3-kinase; VEGF; vascular endothelial growth factor; VE-PTP; vascular e

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Outcomes of patients with metastatic clear-cell renal cell carcinoma treated with pazopanib after disease progression with other targeted therapies

Keywords: هدف پستانداران رپامایسین; Metastatic renal cell carcinoma; Mammalian target of rapamycin; Pazopanib; Targeted therapy; Tyrosine kinase inhibitor; Angiogenesis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A Phase I Trial of Oral Ridaforolimus (AP23573; MK-8669) in Combination with Bevacizumab for Patients with Advanced Cancers

Keywords: هدف پستانداران رپامایسین; Bevacizumab; mammalian target of rapamycin; phase I; ridaforolimus; solid tumours;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Cholesterol induces cardiac hypertrophy by activating the AKT pathway

Keywords: هدف پستانداران رپامایسین; IGF; insulin growth factor; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; PI3K; phosphatidylinositol-3-kinase; GPCR; G-protein-coupled receptor; mTOR; mammalian target of rapamycin; GSK3β; phospho-glycogen synthase k

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease

Keywords: هدف پستانداران رپامایسین; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; 4EBP1; eukaryotic translation initiation factor 4E (eIF-4E)-binding protein-1; FOXO; Forkhead box-O class transcription factors; FMRP; Fragile-X mental retardation protein; GSK3β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Honokiol: A non-adipogenic PPARγ agonist from nature

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated kinase; ANOVA; analysis of variance; ATCC; American type culture collection; BADGE; bisphenol A diglycidyl ether; BMP; bone morphogenic protein 4; BSA; bovine serum albumin; CMCNa; sodium carboxymethyl cellulose; DMEM; Dulbecco's modif

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A hit to lead discovery of novel N-methylated imidazolo-, pyrrolo-, and pyrazolo-pyrimidines as potent and selective mTOR inhibitors

Keywords: هدف پستانداران رپامایسین; Mammalian target of rapamycin; mTOR kinase inhibitors; PI3K/Akt/mTOR pathway; Structure based design; Oncology;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Rapamycin-induced modulation of miRNA expression is associated with amelioration of HIV-associated nephropathy (HIVAN)

Keywords: هدف پستانداران رپامایسین; MicroRNA; HIV-associated nephropathy; Epithelial mesanchymal transition; Apoptosis; Mammalian target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells

Keywords: هدف پستانداران رپامایسین; DEX; Dexamethasone; FAK; Focal Adhesion Kinase; HSA; human serum albumin; iAR; intracellular androgen receptor; mTOR; mammalian target of rapamycin; mAR; membrane androgen receptor; PAK1; p21-activated kinase 1; p70S6K; S6 kinase; PFA; paraformaldehyde; P

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence

Keywords: هدف پستانداران رپامایسین; OIS; oncogene-induced senescence; MEF; mouse embryonic fibroblast; ERK; extracellular signal-regulated kinase; MEK; mitogen-activated protein kinase kinase; PI3K; phosphatidylinositol 3-kinase; pRb; retinoblastoma tumor suppressor protein; SA-β-Gal; sene

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of constitutive Akt (PKB) phosphorylation by docosahexaenoic acid in the human breast cancer cell line MDA-MB-453

Keywords: هدف پستانداران رپامایسین; PUFA; polyunsaturated fatty acid; RTK; receptor tyrosine kinase; FGFR; fibroblast growth factor receptor; IGFR; insulin-like growth factor receptor; PDK1; phosphoinositide-dependent kinase 1; mTOR; mammalian target of rapamycin; PDGF; platelet-derived gro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2

Keywords: هدف پستانداران رپامایسین; EGFR; Epidermal growth factor receptor; GBM; glioblastoma multiforme; RNAi RNA interference; LRIG1; , leucine-rich repeats and immunoglobulin-like domains 1; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; TMZ; temozolomide; Topo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Interplay between immune responses to HLA and non-HLA self-antigens in allograft rejection

Keywords: هدف پستانداران رپامایسین; Ab; antibody; AEC; airway epithelial cells; Ag; antigen; AGTR1; angiotensin II type 1 receptor; AMR; antibody mediated rejection; APC; antigen presenting cell; BOS; bronchiolitis obliterans syndrome; CAN; chronic allograft nephropathy; CAV; cardiac allogr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway

Keywords: هدف پستانداران رپامایسین; 3-MA; 3-methyladenine; AO; acridine orange; MAP-LC3; microtubule-associated protein-light chain 3; MDC; monodansylcadaverine; mTOR; mammalian target of rapamycin; p70S6K; p70-S6 kinase; PKCδ; protein kinase Cδ; TEM; transmission electron microscopy; Wog

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Enhancement of long-term depression by soluble amyloid β protein in rat hippocampus is mediated by metabotropic glutamate receptor and involves activation of p38MAPK, STEP and caspase-3

Keywords: هدف پستانداران رپامایسین; Aβ; amyloid-β protein; AD; Alzheimer's disease; AMPAR; a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; DHPG; 3,5-dihydroxyphenylglycine; EPSP; excitatory postsynaptic potential; fEPSPs; field excitatory postsynaptic potentials; LTP; lon

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo

Keywords: هدف پستانداران رپامایسین; Rapa; rapamycin; ELPs; elastin-like polypeptides; FKBP; FK506 binding protein 12; mTOR; mammalian target of rapamycin; ITC; inverse transition cycling; CMT; critical micelle temperature; CMC; critical micelle concentration; DLS; dynamic light scattering;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

p90RSKs mediate the activation of ribosomal RNA synthesis by the hypertrophic agonist phenylephrine in adult cardiomyocytes

Keywords: هدف پستانداران رپامایسین; 4SU; 4-thiouridine; ARVC; adult rat ventricular cardiomyocytes; CH; cardiac hypertrophy, ChIP, chromatin immunoprecipitation; ERK; extracellular ligand-regulated kinase; MEK; mitogen-activated protein kinase kinase; mTOR; mammalian target of rapamycin; mT

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Radiosensitization of prostate cancer cells by the dual PI3K/mTOR inhibitor BEZ235 under normoxic and hypoxic conditions

Keywords: هدف پستانداران رپامایسین; PI3K; phospho inositide-3 kinase; mTOR; mammalian target of rapamycin; HRF; hypoxia reduction factor; SER; sensitization enhancement ratio; Prostate cancer; PI3K; mTOR; Ionizing radiation; Hypoxia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots

Keywords: هدف پستانداران رپامایسین; Autophagy; LC3-I/II; QDs; Synaptic plasticity; Synapsin-I; Synapse density; QD; quantum dot; LC3; light chain protein 3; PE; phosphatidylethanolamine; mTOR; mammalian target of rapamycin; LTP; long-term potentiation; I/O; input/output; PPF; paired-pulse f

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle

Keywords: هدف پستانداران رپامایسین; 4E-BP1; eukaryotic initiation factor 4E-binding protein 1; AMPK; AMP-activated protein kinase; eEF2; eukaryotic elongation factor 2; eIF; eukaryotic initiation factor; ERK; extracellular-signal-regulated kinase; MEK; mitogen-activated protein kinase/extra

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Identity crisis of Th17 cells: Many forms, many functions, many questions

Keywords: هدف پستانداران رپامایسین; JAK; janus kinase; STAT; signal transducer activator of transcription; mTOR; mammalian target of rapamycin; GCN2; general controlled non-derepressible 2; Th17 cells; Plasticity; IL-17; RORC; RORγt; CCR6; CD161;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

TCDD induces the expression of insulin-like growth factor binding protein 4 in 5L rat hepatoma cells: A cautionary tale of the use of this cell line in studies on dioxin toxicity

Keywords: هدف پستانداران رپامایسین; AhR; aryl hydrocarbon receptor; AKT1S1; proline-rich AKT1 substrate 1; CYP1A1; cytochrome P450 1A1; 4E-BP1; eukaryotic translation initiation factor 4E-binding protein 1; ERK; extracellular signal-regulated protein kinase; GSK3; glycogen synthase kinase 3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue

Keywords: هدف پستانداران رپامایسین; aP2; fatty acid binding protein 4; ATGL; adipose triacylglycerol lipase; BMI; body mass index; CGI-58; α/β-hydrolase domain containing 5; CNI; calcineurin inhibitor; CsA; cyclosporin A; DGAT1; diglyceride acyltransferase 1; FAS; fatty acid synthase; FFA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: Potential therapeutic targets for cardiac cachexia

Keywords: هدف پستانداران رپامایسین; Ang II; angiotensin II; AT1R; angiotensin II type 1 receptor; CHF; congestive heart failure; ESRD; end-stage renal disease; ACE; angiotensin-converting enzyme; UPS; ubiquitin proteasome system; ROS; reactive oxygen species; IGF-1; insulin-like growth fact

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of LRRK2 kinase activity stimulates macroautophagy

Keywords: هدف پستانداران رپامایسین; LRRK2; Leucine Rich Repeat Kinase 2; mTOR; Mammalian target of rapamycin; ROC; Ras of Complex Proteins; COR; C-terminal of ROC domain; SDS; Sodium dodecyl sulphate; EDTA; Ethylene di-ammonium tetra acetic acid; DPBS; Dulbecco's phosphate buffered saline;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1

Keywords: هدف پستانداران رپامایسین; ERK; extracellular signal-regulated kinase; TSC-2; tuberous sclerosis 2 protein; mTOR; mammalian target of rapamycin; IRS; insulin receptor substrate; PI3K; phosphoinositide-3-kinase; AKT; protein kinase B; MAPK; mitogen-activated protein kinase; FOXO1; f

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Huang-Lian-Jie-Du-Decotion induced protective autophagy against the injury of cerebral ischemia/reperfusion via MAPK-mTOR signaling pathway

Keywords: هدف پستانداران رپامایسین; HLJDD; Huang-Lian-Jie-Du-Decotion; MCAO; middle cerebral artery occlusion; TTC; 2,3,5-triphenyltetrazolium chloride; HE; hematoxylin-eosin; NO; nitric oxide; MDA; malondialdehyde; GSH; glutathione; GSSG; glutathione disulfide; T-SOD; total superoxide di

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of Akt-mTOR, ubiquitin-proteasome and autophagy-lysosome pathways in response to formoterol administration in rat skeletal muscle

Keywords: هدف پستانداران رپامایسین; Actb; actin beta; Atg; autophagy-related; Bnip3; BCL2/adenovirus E1B interacting protein 3; BSA; bovine serum albumin; COPD; chronic obstructive pulmonary disease; CREB; cAMP response element binding protein; EDL; extensor digitorum longus; eIF3-f; eukary

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Crosstalk between apoptosis, necrosis and autophagy

Keywords: هدف پستانداران رپامایسین; AIF; Apoptosis Inducing Factor; AMPK; Adenosine Monophosphate activated Kinase; APAF1; Apoptotic Protease Activating Factor 1; BCL-2; B-cell lymphoma 2; BCL-Xl; B-cell lymphoma extra large; BEC1; Beclin-1; BH; Bcl-2 homology; cIAP1; cellular inhibitor of

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

p70S6 kinase is a target of the novel proteasome inhibitor 3,3′-diamino-4′-methoxyflavone during apoptosis in human myeloid tumor cells

Keywords: هدف پستانداران رپامایسین; AML; acute myeloid leukemia; DD1; 3,3′-diamino-4′-methoxyflavone; DNFAA; 2′,3-dinitroflavone-8-acetic acid; 4EBP1; eukaryotic translation initiation factor 4E binding protein 1; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; LPS; lipopolys

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Sorafenib enhances proteasome inhibitor-mediated cytotoxicity via inhibition of unfolded protein response and keratin phosphorylation

Keywords: هدف پستانداران رپامایسین; Ab; antibody; ALLN; acetyl-leucyl-leucyl-norleucinal; ATF; activating transcription factor; CHOP; C/EBP homologous protein; DAPI; 4', 6-diamidino-2-phenylindole; eIF2; eukaryotic translation-initiation factor 2; ER; endoplasmic reticulum; GADD153; growth

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Autophagy, polyphenols and healthy ageing

Keywords: هدف پستانداران رپامایسین; AD; Alzheimer's disease; AMP; adenosine monophosphate; AMPK; adenosine monophosphate activated protein kinase; APP; amyloid beta precursor protein; Atg; autophagy (related gene); ATP; adenosine triphosphate; AV; autophagic vacuoles; Aβ; amyloid beta; Bcl

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Malignant Epithelioid Angiomyolipoma: Tumor and Metabolic Response to Everolimus as Evaluated With Positron Emission Tomography

Keywords: هدف پستانداران رپامایسین; Angiomyolipoma; Imaging; Kidney tumors; Lymphoma; Mammalian target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Impaired lipid accumulation in the liver of Tsc2-heterozygous mice during liver regeneration

Keywords: هدف پستانداران رپامایسین; TSC; tuberous sclerosis; mTOR; mammalian target of rapamycin; GAP; GTPase-activating protein; MAPK; mitogen-activated protein kinase; p90 RSK; p90 ribosomal S6 kinase; ERK; extracellular signal-regulated kinase; P70S6K; p70 ribosomal S6 kinase; AMPK; 5′

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Belinostat-induced apoptosis and growth inhibition in pancreatic cancer cells involve activation of TAK1-AMPK signaling axis

Keywords: هدف پستانداران رپامایسین; AMPK; AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; HDACi; histone deacetylases inhibitor; NAC; N-acetyl-cysteine; (mTOR); mammalian target of rapamycin; ROS; reactive oxygen species; TAK1; transforming growth factor-β-activating kinase 1; H

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Impact of targeting insulin-like growth factor signaling in head and neck cancers

Keywords: هدف پستانداران رپامایسین; IGF; insulin-like growth factor; IGF-1-R; insulin-like growth factor-1 receptor; IRS; insulin receptor substrate; IGFBP; insulin-like growth factor binding protein; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; MAPK; mitogen-activa

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه