دانلود مقالات ISI درباره دائمی Michaelis-Menten + ترجمه فارسی

تغییرات متابولیکی در سرطان کولورکتال انسانی و بافت های اطراف آن: تغییرات در تنظیم تنفس میتوکندری و فلوئور متابولیسم

Metabolic remodeling in human colorectal cancer and surrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes

Keywords: دائمی Michaelis-Menten; AK; adenylate kinase; ANT; adenine nucleotide translocator; AP5A; diadenosine pentaphosphate; BSA; bovine serum albumin; BB-CK; - brain type creatine kinase; CAT; carboxyatractyloside; CIMP; CpG island methylator phenotype; COX; cytochrome c oxidase; CK

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

ترکیب مولکول های کوچک یا بیولوژیک به نانو فیبر برای آزادی دارو بهینه: بررسی

Incorporating small molecules or biologics into nanofibers for optimized drug release: A review

Keywords: دائمی Michaelis-Menten; BCS; biopharmaceutics classification system; bFGF; basic fibroblast growth factor; BMC; bone morphogenetic protein; CA; cellulose acetate; CD; cyclodextrin; CS; chitosan; CS-EDTA; chitosan-ethylenediaminetetraacetic acid; CR; controlled release; DMAc;

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2015 سفارش ترجمه

تشخیص هدایت الکتریکی بدون تماس برای غربالگری بسترهای میروزیناز توسط الکتروفورز مویرگی

Contactless conductivity detection for screening myrosinase substrates by capillary electrophoresis

Keywords: دائمی Michaelis-Menten; C4D; contactless capacitively coupled conductivity detector; CPA; corrected peak area; GLS; glucosinolate; Km; Michaelis-Menten constant; Vmax; maximum velocity; Contactless capacitively coupled conductivity detector (C4D); Enzyme kinetics; Glucosinolat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

ارزیابی تأثیرات اختلالات کودک / بزرگسالان در اثر مصرف کبد اول بر فاکتور تعدیل سینتکس انسانی برای سموم مصرف شده

Assessing the impact of child/adult differences in hepatic first-pass effect on the human kinetic adjustment factor for ingested toxicants

Keywords: دائمی Michaelis-Menten; ADH; alcohol dehydrogenase; BSA; body surface area; BH; body height; BW; body weight; Clint; intrinsic clearance; Clintad; intrinsic clearance in average adult; Clintind; intrinsic clearance in any individual; CAss; arterial blood concentration at steady-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

رشته های آنالوگهای پلیآمین: از زیربنای به سوی مهارکننده های مونوآمین اکسیدازها

Novel polyamine analogues: From substrates towards potential inhibitors of monoamine oxidases

Keywords: دائمی Michaelis-Menten; Monoamine oxidase (MAO); Inhibitors; Isothiocyanate; Polyamine derivatives; Docking studies; BZA; benzylamine; tyramine; p-tyramine; MAO; monoamine oxidase; VAP-1; semicarbazide-sensitive amine oxidase/vascular-adhesion-protein-1; Bis-Bza-Diado; N1,N12-di

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

مدل فارماکوکینتیک مبتنی بر فیزیولوژیک برای افراد خوراکی در معرض کروم است

Physiologically based pharmacokinetic model for humans orally exposed to chromium

Keywords: دائمی Michaelis-Menten; CL; lumen Cr concentration; Cr; chromium; Cr(III); trivalent chromium; Cr(VI); hexavalent chromium; GI; gastrointestinal; KM; Michaelis-Menten constant; KRED; Rate constant for Cr(VI) reduction; L; Small intestines section length; PBPK; physiologically

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of human pharmaceuticals common to aquatic environments on hepatic CYP1A and CYP3A-like activities in rainbow trout (Oncorhynchus mykiss): An in vitro study

Keywords: دائمی Michaelis-Menten; Fish microsomes; Cytochrome P450; Inhibition; Mixture of compounds; Antidepressant; Ki; inhibition constant or equilibrium dissociation constant for the enzyme-inhibitor complex; Km; Michaelis-Menten constant; ER; 7-ethoxyresorufin; EROD; 7-ethoxyreso

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Metabolic engineering of mevalonate-producing Escherichia coli strains based on thermodynamic analysis

Keywords: دائمی Michaelis-Menten; 2PG; 2-phosphoglycerate; 3PG; 3-phosphoglycerate; 6PG; 6-phosphogluconate; 6PGDH; 6-phosphogluconate dehydrogenase; 6PGL; 6-phosphogluconolactonase; AcCoA; acetyl coenzyme A; ACO; cis-aconitate; AKG; α-ketoglutarate; CIT; citrate; CoA; coenzyme A; DHAP;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Kinetic characteristics of L-lysine α- oxidase from Trichoderma cf. aureoviride Rifai VKM F-4268D: Substrate specificity and allosteric effects

Keywords: دائمی Michaelis-Menten; L-lysine α-oxidase; Substrate specificity; Positive cooperativity; Hill coefficient; Michaelis-Menten constant; Kinetic scheme;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Construction and comparison of different source neuraminidase candidate vaccine strains for human infection with Eurasian avian-like influenza H1N1 virus

Keywords: دائمی Michaelis-Menten; Influenza virus; A (H1N1); Eurasian avian-like influenza; Reverse genetic; Vaccine; EA; Eurasian avian-like; CVV; candidate vaccine virus; HN42443; A/Hunan/42443/2015; HA; hemagglutinin; NA; neuraminidase; PR8; A/Puerto Rico/8/34; MDCK; Madin-Darby cani

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Determinants of Intestinal Availability for P-glycoprotein Substrate Drugs Estimated by Extensive Simulation With Mathematical Absorption Models

Keywords: دائمی Michaelis-Menten; drug-drug interaction; P-glycoprotein; physiologically based pharmacokinetic model; modeling and simulation; intestinal absorption; substrate drug; CLh; hepatic clearance; CLr; renal clearance; CYP3A; cytochrome P450 3A; DDI; drug-drug interaction; EQ

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

In vitro effects of the citrus flavonoids diosmin, naringenin and naringin on the hepatic drug-metabolizing CYP3A enzyme in human, pig, mouse and fish

Keywords: دائمی Michaelis-Menten; Diosmin (PubChem CID: 5353588); Naringin (PubChem CID: 25075); Naringenin (PubChem CID: 932); Ki; inhibition constant or equilibrium dissociation constant for the enzyme-inhibitor complex; Km; Michaelis-Menten constant; BFC; 7-benzyloxy-4-trifluoromet

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

A hydrogen peroxide safety valve: The reversible phosphorylation of catalase from the freeze-tolerant North American wood frog, Rana sylvatica

Keywords: دائمی Michaelis-Menten; Akt; Protein kinase B; AMPK; Adenosine monophosphate-activated protein kinase; cAMP; Cyclic adenosine monophosphate; CAMK; Calmodulin dependent kinase; Cdc2; Cyclin dependent kinase 1; Cdk5; Cyclin dependent kinase 5; cGMP; Cyclic guanidine monophosphate;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Photocurrents from photosystem II in a metal oxide hybrid system: Electron transfer pathways

Keywords: دائمی Michaelis-Menten; β-DDM; n-Dodecyl β-d-maltoside; DCBQ; 2,6-dichloro-1,4-benzoquinone; DCMU; 3-(3,4-dichlorophenyl)-1,1-dimenthylurea; Ef; energetic position of the Fermi level; Em; midpoint potential; EV; energetic position of the valence band; Ec; energetic position of

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Aqueous extracts and suspensions of restructured pork formulated with Undaria pinnatifida, Himanthalia elongata and Porphyra umbilicalis distinctly affect the in vitro α-glucosidase activity and glucose diffusion

Keywords: دائمی Michaelis-Menten; Alpha-glucosidase; Glucose diffusion; Restructured pork; Inhibition mechanism; Hypoglycaemic effects; CVD; cardiovascular disease; CRP; control-RP; GOD; glucose oxidase; Ki; inhibition constant; Km; Michaelis-Menten constant; NRP; restructured pork cont

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Free-radical first responders: The characterization of CuZnSOD and MnSOD regulation during freezing of the freeze-tolerant North American wood frog, Rana sylvatica

Keywords: دائمی Michaelis-Menten; ALS; amyotrophic lateral sclerosis; AMPK; 5′ adenosine monophosphate-activated protein kinase; Cm; the denaturant concentration at which half of the protein is unfolded; CuZnSOD; copper and zinc containing SOD; DEAE+; diethylaminoethyl cellulose; DEPC;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Functionalized fullerene (C60) as a potential nanomediator in the fabrication of highly sensitive biosensors

Keywords: دائمی Michaelis-Menten; Au; gold; C60[C(COOH)2]2; carboxyl-modified fullerene; C60-NCNTs/CHIT; fullerene-nitrogen doped carbon nanotubes and chitosan; ChO; choline oxidase; CNO; carbon nano-onions; CNT; carbon nanotube; CS; chitosan; Cys; l-Cysteine; DWCNT; double walled carbon

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Enediynyl peptides and iso-coumarinyl methyl sulfones as inhibitors of proprotein convertases PCSK8/SKI-1/S1P and PCSK4/PC4: Design, synthesis and biological evaluations

Keywords: دائمی Michaelis-Menten; aa; amino acid; AMC; 7-amino 4-methyl coumarin; Amu; atomic mass unit; Au; arbitrary unit; Aufs; absorption units full scale; IMS; iso-coumarinyl methyl sulfone; Eda; enediyne amino acid; h; human; IC50; inhibitor concentration required for 50% inhibition

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

In vitro effect of important herbal active constituents on human cytochrome P450 1A2 (CYP1A2) activity

Keywords: دائمی Michaelis-Menten; Herbal active constituents; CYP1A2; Fluorescence-based enzyme assay; Inhibitory effect; CEC; 3-cyano-7-ethoxycoumarin; CYP; cytochrome P450; DMSO; dimethylsulfoxide; Km; Michaelis-Menten constant; Vmax; maximum velocity; IC50; the half maximal (50%) inh

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

An electrochemical biosensor with nanointerface for lactate detection based on lactate dehydrogenase immobilized on zinc oxide nanorods

Keywords: دائمی Michaelis-Menten; Zinc oxide nanorods; Biosensor; Lactic acid; Maximum rate; Michaelis-Menten constant;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Purification and characterization of a new carbonyl reductase from Leifsonia xyli HS0904 involved in stereoselective reduction of 3,5-bis(trifluoromethyl) acetophenone

Keywords: دائمی Michaelis-Menten; Carbonyl reductase; Leifsonia xyli; (R)-3,5-bis(trifluoromethyl) phenyl ethanol; Purification; Characterization; Asymmetric reduction; BTAP; 3,5-bis(trifluoromethyl) acetophenone; BTPE; 3,5-bis(trifluoromethyl)phenyl ethanol; ee; enantiometric excess; Vma

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Geranylated flavonoids displaying SARS-CoV papain-like protease inhibition from the fruits of Paulownia tomentosa

Keywords: دائمی Michaelis-Menten; IC50; the inhibitor concentration leading to 50 % activity loss; Ki; inhibition constant; Km; Michaelis-Menten constant; SARS-CoV PLpro; Paulownia tomentosa; Geranylated flavonoids; PLpro inhibitor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

E. coli sabotages the in vivo production of O-linked β-N-acetylglucosamine-modified proteins

Keywords: دائمی Michaelis-Menten; O-GlcNAc; O-linked β-N-acetylglucosamine; NagZ; E. coli β-N-acetylglucosaminidase; OGT; O-GlcNAc transferase; OGA; O-GlcNAcase; UDP-GlcNAc; uridine 5′-diphospho-N-acetylglucosamine; CREB1; human cAMP responsive element-binding protein; Q2; second glut

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis and evaluation of copper complexes of Schiff-base condensates from 5-substituted-2-hydroxybenzaldehyde and 2-substituted-benzenamine as selective inhibitors of protein tyrosine phosphatases

Keywords: دائمی Michaelis-Menten; Copper complexes; Protein tyrosine phosphatases; Selective inhibitor; Schiff base; CSD; Cambridge Structural Database; ESI-MS; electrospray ionization mass spectra; Hcpmp; 4-chloro-2-((phenylimino)methyl)phenol; Hnpmp; 4-bromo-2-((phenylimino)methyl)pheno

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2013 سفارش ترجمه

High density lipoprotein is an inappropriate substrate for hepatic lipase in postmenopausal women

Keywords: دائمی Michaelis-Menten; PMW; Postmenopausal women; PreMW; Premenopausal women; PHP; Post-heparin plasma; FFA; Free fatty acids; CETP; Cholesteryl ester transfer protein; Km(app); Michaelis-Menten constant; Vmax; Maximum reaction velocity; High density lipoprotein; Postmenopaus

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Starch supplementation modulates amylase enzymatic properties and amylase B mRNA level in the digestive gland of the Pacific oyster Crassostrea gigas

Keywords: دائمی Michaelis-Menten; α-amylase; Crassostrea gigas; digestive enzyme; Michaelis-Menten constant; regulation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Cholinestrase inhibitory effects of geranylated flavonoids from Paulownia tomentosa fruits

Keywords: دائمی Michaelis-Menten; IC50; the inhibitor concentration leading to 50% activity loss; Ki; inhibition constant; Km; Michaelis-Menten constant; Human acetylcholinesterase; Butyrylcholinesterase; Time-dependent inhibitor; Fluorescence quenching; Paulownia tomentosa;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanism of transcription initiation by the yeast mitochondrial RNA polymerase

Keywords: دائمی Michaelis-Menten; mtRNAP; mitochondrial RNAP; Ymt; yeast mitochondrial; Mtf1; mitochondrial transcription factor 1; nt; nucleotides; aa; amino acids; SAM; S-adenosyl-l-methionine; Kd; equilibrium dissociation constant; FRET; fluorescence resonance energy transfer; 2-AP; 2-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Characterisation of thermostable trypsin and determination of trypsin isozymes from intestine of Nile tilapia (Oreochromis niloticus L.)

Keywords: دائمی Michaelis-Menten; SDS-PAGE; sodium dodecyl sulphate-polyacrylamide gel electrophoresis; Km; Michaelis-Menten constant; Kcat; catalytic constant; Kcat/Km; catalytic efficiency; TAME; N-p-tosyl-l-arginine methyl ester hydrochloride; BAPNA; benzoyl-dl-arginine-p-nitroanilid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Pyrimidin-2(1H)-ones based inhibitors of Mycobacterium tuberculosis orotate phosphoribosyltransferase

Keywords: دائمی Michaelis-Menten; Mycobacterium tuberculosis; Tuberculosis; Pyrimidine; Orotate phosphoribosyltransferase; Inhibitors; Pyrimidin-2(1H)-ones compounds; TB; tuberculosis; MTB; Mycobacterium tuberculosis; OPRT; orotate phosphoribosyltransferase; OA; orotate; PRPP; α-d-5-phos

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium

Keywords: دائمی Michaelis-Menten; AUC; area under the curve; CL; lumen Cr concentration; Cr; chromium; Cr(III); trivalent chromium; Cr(VI); hexavalent chromium; GI; gastrointestinal; KM; Michaelis-Menten constant; L; small intestines section length; PBPK; physiologically based pharmacok

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2012 سفارش ترجمه

Glycosylation, amino acid analysis and kinetic properties of a major Kunitz-type trypsin inhibitor from Acacia victoriae Bentham seeds

Keywords: دائمی Michaelis-Menten; AvTI; Acacia victoriae trypsin inhibitor; FPLC; fast-performance liquid chromatography; kDa; kiloDaltons; Ki; inhibition constant; Km; Michaelis-Menten constant; Kmapp; apparent Michaelis-Menten constant; ME; β-mercaptoethanol; MW; molecular weight;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Phenoloxidase activity of intact and chemically modified functional unit RvH1-a from molluscan Rapana venosa hemocyanin

Keywords: دائمی Michaelis-Menten; CO; catechol dehydrogenation; CD; circular dichroism; FU; functional unit; Hcs; hemocyanins; HvH; Helix vulgaris Hc; KM; Michaelis-Menten constant; POs; phenoloxidases; RvH; Rapana venosa Hc; RvH1 and RvH2; structural subunits 1 and 2 of Rapana venosa h

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Catalytic mechanism in successive two-step protein-film voltammetry-Theoretical study in square-wave voltammetry

Keywords: دائمی Michaelis-Menten; Protein-film voltammetry; Feedback mechanism; Surface redox reactions; Mathematical modeling; Square-wave voltammograms; Michaelis-Menten constant;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Boophilus microplus cathepsin L-like (BmCL1) cysteine protease: Specificity study using a peptide phage display library

Keywords: دائمی Michaelis-Menten; rBmCL1; recombinant Boophilus microplus cathepsin L-Like; Kcat; turnover number; Ki; inhibition constant; Km; Michaelis-Menten constant; Vmax; maximum velocity; Cysteine proteases; Rhipicephalus (Boophilus) microplus; Protein expression; Enzyme kinetic;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

(d)-Amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Iα

Keywords: دائمی Michaelis-Menten; cGMP; cyclic guanosine 3′,5′-mono-phosphate; i.p.; intraperitoneal; i.v.; intravenous; Ki; inhibition constant; MAP; mean arterial blood pressure; Km; Michaelis-Menten constant; MPP; membrane-permeable peptides; PKA; cAMP-dependent protein kinase; P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

The KH and S1 domains of Escherichia coli polynucleotide phosphorylase are necessary for autoregulation and growth at low temperature

Keywords: دائمی Michaelis-Menten; aa; aminoacids; ADP; adenosin diphosphate; c.f.u.; colony forming units; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; H; six-histidine tag; IPTG; isopropyl-beta-d-thiogalactopyranoside; Kd; dissociation constant; kDa; kilo Daltons; Km; Mich

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Identification of monoamine oxidase and cytochrome P450 isoenzymes involved in the deamination of phenethylamine-derived designer drugs (2C-series)

Keywords: دائمی Michaelis-Menten; 2C-B; 4-bromo-2,5-dimethoxy-β-phenethylamine; 2C-I; 4-iodo-2,5-dimethoxy-β-phenethylamine; 2C-D; 2,5-dimethoxy-4-methyl-β-phenethylamine; 2C-E; 4-ethyl-2,5-dimethoxy-β-phenethylamine; 2C-T-2; 4-ethylthio-2,5-dimethoxy-β-phenethylamine; 2C-T-7; 2,5-di

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Fluorescence probes used for detection of reactive oxygen species

Keywords: دائمی Michaelis-Menten; ROS; reactive oxygen species; O2•−; superoxide radical; HO2•; hydroperoxyl radical; HO•; hydroxyl radical; ROO•; peroxyl radical; RO•; alkoxyl radical; H2O2; hydrogen peroxide; 1O2; singlet oxygen; HOCl; hypochlorous acid; UV; ultraviolet; RNS

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2005 سفارش ترجمه