NGF serum levels variations in major depressed patients receiving duloxetine
Keywords: NGF; Depression; Duloxetine; Neuro-endocrine-immune system;
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Increased serum brain-derived neurotrophic factor (BDNF) levels in patients with narcolepsy
Keywords: Narcolepsy; BDNF; Sleep; Orexin; Hypocretin; NGF;
Optimisation of culture conditions for differentiation of C17.2 neural stem cells to be used for in vitro toxicity tests
Keywords: BDNF; brain-derived neurotrophic factor; DMEM; Dulbecco's minimal essential medium; FCS; fetal calf serum; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; HS; horse serum; NGF; nerve growth factor; RA; all-trans r
Differential regulation of SC1/PRDM4 and PRMT5 mediated protein arginine methylation by the nerve growth factor and the epidermal growth factor in PC12 cells
Keywords: SC1; Schwann cell factor 1; PRMT; protein arginine methyltransferase; PRDM; positive regulatory domain protein; NGF; nerve growth factor; EGF; epidermal growth factor; NSC; neural stem cells; (H)MTase; (histone) methyltransferase; PRDM4; PRMT5; Histone ar
Research reportNeotrofin reverses the effects of chronic unpredictable mild stress on behavior via regulating BDNF, PSD-95 and synaptophysin expression in rat
Keywords: AD; Alzheimer's disease; ANOVA; analysis of variance; BDNF; brain derived neurotrophic factor; CUMS; chronic unpredictable mild stress; NGF; nerve growth factor; NT-3; neurotrophin-3; NT-4; neurotrophin-4; PSD-95; postsynaptic density protein 95; Neotrofi
Basic NeuroscienceA dual compartment diffusion chamber for studying axonal chemotaxis in 3D collagen
Keywords: Axon guidance; Gradient; Chemotropism; NGF; Slit2;
Coenzyme Q10 protects Pc12 cells from cisplatin-induced DNA damage and neurotoxicity
Keywords: CoQ10; coenzyme Q10; NGF; nerve growth factor; MNi; micronuclei; NBUDs; nuclear buds; NPBs; nucleoplasmatic bridges; OD; optical density; ROS; reactive oxygen species; WS-CoQ10; water-soluble formulation of coenzyme Q10; Ubiquinone; Neuroprotective agent;
Polyadenylation site-specific differences in the activity of the neuronal βCstF-64 protein in PC-12 cells
Keywords: Add2; mouse gene encoding β-adducin; CstF; cleavage stimulation factor; CstF-64; cleavage stimulation factor, 64,000 Mr subunit; βCstF-64; brain-specific splice variant of CstF-64; CstF-77; cleavage stimulation factor, 77,000 Mr subunit; Cstf2; mouse or
Nemo-like kinase, a multifaceted cell signaling regulator
Keywords: NLK; Nemo-like kinase; IL-6; intereukin-6; MAPK; mitogen activated protein kinase; ERK; extracellular-signal regulated kinase; Pro; proline; Ser; serine; Thr; threonine; C. elegans; Caenorhabditis elegans; POP-1; Posterior pharynx defect protein 1; LEF1;
TRPC3 regulates release of brain-derived neurotrophic factor from human airway smooth muscle
Keywords: ASM; airway smooth muscle; BAL; bronchial alveolar lavage; BAPTA; 1,2-bis(o-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid; BDNF; brain-derived neurotrophic factor; NT; neurotrophins; ELISA; enzyme linked immunosorbent assay; GFP; green fluorescent pr
Nerve growth factor/p75 neurotrophin receptor-mediated sensitization of rat sensory neurons depends on membrane cholesterol
Keywords: APs; action potentials; DRG; dorsal root ganglia; EGTA; ethylenediamine tetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; MβCD; methyl-β-cyclodextrin; MPL; 1-methyl-2-pyrrolidinone; NGF; nerve growth factor; p75NTR; p75 neurot
Sympathetic denervation of peri-infarct myocardium requires the p75 neurotrophin receptor
Keywords: BDNF; brain-derived neurotrophic factor; HA; hemagglutinin; 123I-MIBG; iodine-123 meta-iodobenzylguanidine; LAD; left anterior descending coronary artery; MI; myocardial infarction; NGF; nerve growth factor; NE; norepinephrine; p75NTR; p75 neurotrophin re
Oligodendrogenesis from neural stem cells: Perspectives for remyelinating strategies
Keywords: MS; multiple sclerosis; NPCs; neural precursor cells; CNS; central nervous system; PDGFRα; platelet-derived growth factor receptor alpha; OPCs; oligodendrocyte precursor cells; PNS; peripheral nervous system; NSCs; neural stem cells; SVZ; subventricular
Genotoxicity of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQâ¢)
Keywords: 2AA; 2-aminoanthracene; AF-2; 2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide; B[a]P; benzo[a]pyrene; bw; body weight; CHL; Chinese hamster lung; DMSO; dimethyl sulfoxide; GSH; glutathione; ICH; International Conference on Harmonization; ICR-191; -methoxy-6-ch
A screen for inducers of p21waf1/cip1 identifies HIF prolyl hydroxylase inhibitors as neuroprotective agents with antitumor properties
Keywords: CPO; ciclopirox; DFO; desferrioxamine; DHB; 3,4-dihydroxybenzoate; DMOG; dimethyloxallyl glycine; HIF; hypoxia inducible factor; NGF; nerve growth factor; PHD; proyl-4-hydroxylase; p21; Neuroprotection; Antitumor; Prolyl hydroxylase inhibitors; Neuronal o
MAGI-1 acts as a scaffolding molecule for NGF receptor-mediated signaling pathway
Keywords: NGF; nerve growth factor; MAGI-1; membrane-associated guanylate kinase with inverted organization-1; MAGUK; membrane-associated guanylate kinase; PDZ; PSD-95/Discs Large/Zona Occludens; Trk; tropomyosin-related kinase; DMEM; Dulbecco's modified Eagle's me
Rit subfamily small GTPases: Regulators in neuronal differentiation and survival
Keywords: CA; constitutively active; cAMP; cyclic adenosine monophosphate; CaM; calmodulin; CCI; controlled cortical impact; CREB; cAMP response element binding protein; CRIB; Cdc42/Rac interactive binding; DA; dopamine; DAT; dopamine transporter; DN; dominant nega
Membrane microdomain determines the specificity of receptor-mediated modulation of Kv7/M potassium currents
Keywords: lipid raft; receptor; Kv7/M current; modulation; specificity; B2R; bradykinin receptor; BK; bradykinin; DRG; dorsal root ganglion; EC50; 50% effective concentration; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; GPCR; G pr
The role of Src protein in the process formation of PC12 cells induced by the proteasome inhibitor MG-132
Keywords: Cy3; Â a fluorophor cyanin dye; DMEM; Â Dulbecco's Modified Eagle's Medium; DMSO; Â dimethyl-sulfoxyde; EDTA; Â ethylenediaminetetraacetic acid; EGTA; Â ethylene glycol tetraacetic acid; ERK1/2; Â extracellular signal-regulated kinase 1 and 2; H-Ras;
Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth
Keywords: BBR; Berberine; Bcl-2; B-cell lymphoma 2; HO-1; Hemeoxygenase-1; IGF-1; Insulin growth factor-1; LDH; Lactate dehydrogenase; MTT; 3-(4,5-dimethyl- thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide; NGF; Nerve growth factor; Nrf2; Nuclear erythroid 2-related
Expression and localization of receptor protein tyrosine phosphatase β and its ligand pleiotrophin in the submandibular gland of mice
Keywords: SMG; submandibular gland; SLG; sublingual gland; ID; intercalated duct; SD; striated duct; GCT; granular convoluted tubule; RPTPβ; receptor protein tyrosine phosphatase β; PTN; pleiotrophin; NGF; nerve growth factor; IHC; immunohistochemistry; RPTPβ; P
STAT3 integrates cytokine and neurotrophin signals to promote sympathetic axon regeneration
Keywords: STAT3; signal transducer and activator of transcription 3; LIF; leukemia inhibitory factor; CNTF; ciliary neurotrophic factor; DBH; dopamine-β-hydroxylase; MI; myocardial infarction; NGF; nerve growth factor; BDNF; brain-derived neurotrophic factor; TrkA
Involvement of the α7-nicotinic acetylcholine receptors in the anti-inflammatory action of the thymulin-related peptide (PAT)
Keywords: Ach; acetylcholine; ANOVA; analysis of variance; BAPTA; 1,2-bis (o-aminophenoxy) ethane-N,N,Nâ²,Nâ²-tetraacetic acid; ELISA; enzyme-linked immunosorbent assay; ET; endotoxin; HEPES; 4-(2-hydroxyethyl) piperazineethanesulfonic acid; HP; hot plate; ICV; i
Satellite glia cells in dorsal root ganglia express functional NMDA receptors
Keywords: BP; blocking peptide; BSA; bovine serum albumin; [Ca2+]cyt; cytoplasmic calcium; DRG; dorsal root ganglia; EDTA; ethylenediamine tetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; NDS; normal donkey serum; NGF; nerve growth facto
Companions reverse stressor-induced decreases in neurogenesis and cocaine conditioning possibly by restoring BDNF and NGF levels in dentate gyrus
Keywords: DG; dentate gyrus; NGF; nerve growth factor; BDNF; brain-derived neurotrophic factor; NT-3; neurotrophic-3; CPP; conditioned place preference; CORT; corticosterone; DHF; 7,8-dihydroxyflavone; Social support; Stressor; Neurotrophins; Neurogenesis; Cocaine;
The generation of NGF-secreting primary rat monocytes: A comparison of different transfer methods
Keywords: Primary monocytes; Transfection; Transduction; NGF;
Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs
Keywords: ABCC; ATP-binding cassette, subfamily C; ARE; Antioxidant-response element; CA; carnosic acid; CS; Carnosol; DA; Dopamine; DMF; Dimethyl fumarate (also known as BG-12); DOX; Doxorubicin (also known as adriamycin); EP; Electrophile; GCLM; Glutamyl cysteine
Research ReportEndothelin B receptor agonist, IRL-1620, enhances angiogenesis and neurogenesis following cerebral ischemia in rats
Keywords: MCAO; middle cerebral artery occlusion; SVZ; subventricular zone; VEGF; vascular endothelial growth factor; NeuN; neuronal nuclei; GFAP; glial fibrillary acidic protein; BrdU; bromodeoxyuridine; NGF; nerve growth factor; ET; endothelin; Endothelin B recep
A HaloTag® method for assessing the retrograde axonal transport of the p75 neurotrophin receptor and other proteins in compartmented cultures of rat sympathetic neurons
Keywords: BDNF; brain derived neurotrophic factor; DMSO; dimethylsulfoxide; HT; HaloTag; NGF; nerve growth factor; PBS; phosphate-buffered saline; p75NTR; p75 neurotrophin receptor; SDS; sodium dodecyl sulfate; PAGE; polyacrylamide gel electrophoresis; TMR; tetrame
Sequestosome1/p62: A regulator of redox-sensitive voltage-activated potassium channels, arterial remodeling, inflammation, and neurite outgrowth
Keywords: AP-1; activator protein-1; ARE; antioxidant response element; CDK; cyclin-dependent kinase; EGF; epidermal growth factor; ERK1/2; extracellular regulated kinase 1/2; HNE; 4-hydroxynonenal; HO-1; heme oxygenase-1; IL-1; interleukin-1; Keap1; Kelch-like ECH
Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation
Keywords: Cell commitment; Cell survival; Endocannabinoids; Membrane receptors; Niche cues; Protein kinases; Transcription factors; 2-AG; 2-arachidonoylglycerol; AEA; N-arachidonoylethanolamine; BDNF; brain derived neurotrophic factor; CBD; cannabidiol; CBG; cannab
Neuroprotective effects of NGF, BDNF, NT-3 and GDNF on axotomized extraocular motoneurons in neonatal rats
Keywords: ALS; amyotrophic lateral sclerosis; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; BSA; bovine serum albumin; ChAT; choline acetyltransferase; CNS; central nervous system; DAB; 3,3â²-diaminobenzidine tetrahydrochloride; GDNF; glial
Minimal NF-κB activity in neurons
Keywords: AP5; 2-amino-5-phosphonopentanoate; BDNF; brain-derived neurotrophic factor; BRN; mixed brain cells; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CxN; cortical neurons; DMEM; Dulbecco's modified Eagle's medium; EDTA; ethylenediaminetetraacetic acid; EG
Topical anti-inflammatory and analgesic activities of standardized pomegranate rind extract in comparison with its marker compound ellagic acid in vivo
Keywords: CIA; collagen-induced arthritis; CFA; complete Freund's adjuvant; COX; cyclooxygenase; ctrl; control; DF; diclofenac; EA; ellagic acid; HTAB; hexadecyltrimethylammonium bromide; IL-1β; interleukin-1 beta; iNOS; inducible NO synthase; LPS; lipopolysacchar
Tau protein kinases: Involvement in Alzheimer's disease
Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Arg; Abl-related gene; SFK; Src family kinase; Aβ; β-amyloid; BBB; blood brain barrier; LD50; lethal dose 50; c-Abl; c-Abelson; Cables; c-Abl-binding adaptator protein; CaMKII; Ca2+/calmodulin-dep
The p75NTR signaling cascade mediates mechanical hyperalgesia induced by nerve growth factor injected into the rat hind paw
Keywords: AP; action potential; aPKC; atypical protein-kinase C; C2-ceramide; N-acetyl sphingosine; CLP; contralateral paw; DMSO; dimethyl sulfoxide; DRG; dorsal root ganglia; GSH; glutathione; IgG; immunoglobulin G; i.pl.; intraplantar; IPSI; ipsilateral paw; mPSI
Intracellular interaction of newly synthesized nerve growth factor and its receptors
Keywords: Autocrine; NGF; TrkA; p75NTR; MAP kinase; PC12 cells
Higher levels of brain derived neurotrophic factor but similar nerve growth factor in human milk in women with preeclampsia
Keywords: NGF, nerve growth factor; BDNF, brain derived neurotrophic factor; DHA, docosahexaenoic acid; LCPUFA, long-chain polyunsaturated fatty acidsHuman milk; NGF; BDNF; Neurotrophins; Preeclampsia; Birth measures
Two-dimensional surface plasmon resonance imager: An approach to study neuronal differentiation
Keywords: 2D–SPRI; PC12 cell; NGF; Neuronal differentiation
Onabotulinumtoxin-A intradetrusorial injections modulate bladder expression of NGF, TrkA, p75 and TRPV1 in patients with detrusor overactivity
Keywords: Detrusor overactivity; NGF; TrkA; p75; TRPV1; Botulinum A toxin
Cancer-induced bone pain: Mechanisms and models
Keywords: Syngenic tumor model; ASIC; NGF; Cytokines; Glutamate; Oxidative Stress
Mast cells on the mind: new insights and opportunities
Keywords: mast cells; neuroimmune interactions; psychiatric disease; multiple sclerosis; ischemia; NGF
Aerobic endurance capacity affects spatial memory and SIRT1 is a potent modulator of 8-oxoguanine repair
Keywords: 8-oxoG; 8-oxo-7,8-dihydroguanine; Ac; acetylated; AcOgg1; acetylated 8-oxoguanine DNA glycosylase-1; AP; abasic; APE1; apurinic apyrimidinic endonuclease1; BER; base excision repair; BrdU; 5-bromo-2â²-deoxyuridine; DNPH; 4-dinitrophenylhydrazine; ERK; ex
Bioelectronics meets nanomedicine for cardiovascular implants: PEDOT-based nanocoatings for tissue regeneration
Keywords: AFM; Atomic Force Microscopy; DES; Drug eluting stents; DL; Drude-Lorentz model; DMSO; Dimethyl sulfoxide; NGF; Nerve growth factor; PBS; Phosphate-buffered saline; PEDOT; Poly (3,4-ethylenedioxythiophene); PEG; Polyethylene glycol; PSS; Polystyrenesulf
Impairment of the septal cholinergic neurons in MPTP-treated A30P α-synuclein mice
Keywords: L-DOPA; Dementia; Parkinson's disease; Hippocampus; Medial septum; NGF
Developmental Origins of Functional Dyspepsia-Like Gastric Hypersensitivity in Rats
Keywords: Functional Bowel Disorders; Abdominal Pain; Visceral Hypersensitivity; Early Life Insult; BDNF; brain-derived nerve neurotrophic factor; DRG; dorsal root ganglia; FD; functional dyspepsia; GHS; gastric hypersensitivity; HPA-axis; hypothalamic-pituitary-ad
NGF and nitrosative stress in patients with Huntington's disease
Keywords: Huntington's disease; NGF; BDNF; GDNF; Neurodegeneration; Basal ganglia;
The γ-secretase inhibitor DAPT increases the levels of gangliosides at neuritic terminals of differentiating PC12 cells
Keywords: Aβ; amyloidβ-peptide; AD; Alzheimer disease; APP; β-amyloid precursor protein; ESI; electrospray ionization; GAβ; ganglioside-bound Aβ; LC; liquid chromatography; MRM; multiple reaction monitoring; MS; mass spectrometry; MS/MS; tandem mass spectromet
Regulatory mechanism of PAC1 gene expression via Sp1 by nerve growth factor in PC12 cells
Keywords: PACAP; pituitary adenylate cyclase activating polypeptide; VIP; vasoactive intestinal polypeptide; NGF; nerve growth factor; NRSE; neuron-restrictive silencer elements; Sp1; specificity protein 1; Zac1; zinc finger protein; EMSA; electrophoretic mobility
Neurotrophic factors in obsessive-compulsive disorder
Keywords: Obsessive-compulsive disorder; neurotrophins; BDNF; GDNF; NGF