Keywords: AC; adenylyl cyclase; ALG-2; apoptosis-linked gene 2 product; Alix; ALG-2-interacting protein X; Bcl10; B-cell lymphoma/leukemia protein 10; CaM; calmodulin; CaM-BD; CaM-binding domain; CaM-BP; CaM-binding protein; CARD; caspase-recruitment domain; Carma1
مقالات ISI (ترجمه نشده)
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Keywords: AICA; 5-aminoimidazole-4-carboxamide; AICARFTase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; CA; carbonic anhydrase; CBE; CI-HCO3â exchanger; CHO; Chinese hamster ovary; FR; folate receptor; GARFTase; β-glycinamide ribonucleotide
Keywords: NHE1; Proton transport; Triple-negative breast cancer; Metastasis;
Keywords: VFA; volatile fatty acid; NPL; normal protein level; LPL; low protein level; MR; milk replacer; ME; metabolizable energy; ADG; average daily gain; DM; dry matter; OM; organic matter; CP; crude protein; GE; gross energy; EE; ether extract; NDF; neutral det
Keywords: Preload; Afterload; Calcium sparks; Microdomains; Mechanotransduction; Stretch-induced arrhythmias; AP; action potential; AT; axial tubule; Ca2+; calcium; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CICR; Ca2+ induced Ca2+ release; GSMTx4; Grammo
Keywords: Lactic acidosis; lactate; bicarbonate; base; metabolic acidosis; THAM; Carbicarb; sepsis; hypoxia; aerobic glycolysis; dialysis; NHE1;
Keywords: HCC; hepatocellular carcinoma; DDS; drug delivery system; ECM; extracellular matrix; MVD; microvessel density; EPR; enhanced permeability and retention; ASGP-R; asialoglycoprotein receptor; GPC3; glypican 3; HS chain; heparin sulfate chain; GA; glycyrrhet
Keywords: AQP5; aquaporin-5; BM; basement membrane; BPE; bovine pituitary extract; BSA; bovine serum albumin; CEA; carcinoembryonic antigen; CFTR; cystic fibrosis transmembrane conductance regulator; CJ; cell junctions; D; duct; DAPI; 4â², 6-diamidino-2-phenylindo
Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells
Keywords: CDCl3; Deuterated chloroform; CH2Cl2; Methylene dichloride; 13C NMR; Carbon-13 nuclear magnetic resonance; CoMFA; Comparative molecular field analysis; CuBr.Me2S; Copper bromide dimethyl sulfide; DMEM; Dulbecco's modified eagle medium; DMSO; Dimethyl sulf
Signaling pathways involved in the rapid biphasic effect of aldosterone on Na+/H+ exchanger in rat proximal tubule cells
Keywords: Aldo; Aldosterone; MR; mineralocorticoid receptor; GR; glucocorticoid receptor; pHi; intracellular pH; pHirr; intracellular pH recovery rate; NHE1; basolateral Na+/H+ exchanger isoform 1; [Ca2+]i; cytosolic free calcium concentration; PLC; phospholipase C
Defining the Na+/H+ exchanger NHE1 interactome in triple-negative breast cancer cells
Keywords: ACC1; acetyl-CoA carboxylase; AKT; protein kinase B, PKB; CAII; carbonic anhydrase II; CHP1; calcineurin B homologous protein 1; ER; estrogen receptor; ERK1/2; extracellular signal-regulated kinase 1/2; ERM; ezrin-radixin-moesin; FOXO3a; forkhead box O3a;
A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1)
Keywords: NHE1; Na+/H+ exchanger 1; NHE1cdt; C-terminal distal tail of NHE1; CS; chemical shift; SCS; secondary chemical shift; PTM; posttranslational modification; IDP; SLiM; Phospho-cap; Secondary chemical shifts; NMR;
Environmental carcinogenesis and pH homeostasis: Not only a matter of dysregulated metabolism
Keywords: AhR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; CYP; cytochrome P450; EMT; epithelial-to-mesenchymal transition; Cx43; connexin 43; GJIC; gap junction intercellular communication; HMGCoA reductase; 3-hydroxy-3-methylglutaryl-CoA reductase; NHE1; Na
Combination of sonodynamic with temozolomide inhibits C6 glioma migration and promotes mitochondrial pathway apoptosis via suppressing NHE-1 expression
Keywords: Sonodynamic therapy; NHE1; Glioma cells; Temozolomide; Mitochondrial pathway;
Elevated Na+/H+ exchanger-1 expression enhances the metastatic collective migration of head and neck squamous cell carcinoma cells
Keywords: NHE1; Collective cell migration; Head and neck squamous cell carcinoma; Actin cytoskeleton; Lymph node metastasis; Na+/H+/ exchanger1; NHE1; Head and neck squamous cell carcinoma; HNSCC; Epithelial-mesenchymal transition; EMT; intracellular pH; pHi;
Dual role of LRRC8A-containing transporters on cisplatin resistance in human ovarian cancer cells
Keywords: A2780WT; drug-sensitive human ovarian cancer cells; A2780CisR; cisplatin resistant A2780 cells; ABC; ATP-binding cassette; Ano6; Anoctamin 6; Apaf-1; apoptotic protease activating factor 1; Atox1; Antioxidant 1 copper chaperone; AP; alkaline phosphatase;
KR-33028, a potent inhibitor of the Na+/H+ exchanger NHE1, suppresses metastatic potential of triple-negative breast cancer cells
Keywords: HMA; [5-(N,N-hexamethylene)-amiloride]; NHE1; Na+/H+ exchanger isoform 1; pHi; intracellular pH; TNBC; triple negative breast cancer; NHE1; Triple-negative breast cancer; Metastasis; KR-33028;
Skin pH Is the Master Switch of Kallikrein 5-Mediated Skin Barrier Destruction in a Murine Atopic Dermatitis Model
Keywords: AD; atopic dermatitis; FLG; filaggrin; KLK; kallikrein; LBA; lactobionic acid; LEKTI; lympho-epithelial Kazal-type-related inhibitor; Ngf; nerve growth factor; NHE1; sodium/hydrogen exchanger 1; nLBA; NaOH-neutralized 5% LBA; PAR2; protease-activated rece
Activation of the Na+/H+ exchanger in isolated cardiomyocytes through β-Raf dependent pathways. Role of Thr653 of the cytosolic tail
Keywords: ET-1; endothelin 1; NHE1; Na+/H+ exchanger isoform 1; NRVM; neonatal rat ventricular myocytes; pHi; intracellular pH; β-Raf; Endothelin; Isolated cardiomyocytes; Na+/H+ exchanger; pH regulation;
Na+/H+ antiporter (NHE1) and lactate/H+ symporters (MCTs) in pH homeostasis and cancer metabolism
Keywords: Membrane transporters; NHE1; Lactate transporters; MCTs; pH regulation; Cancer; Mathematical model;
LeftyA sensitive cytosolic pH regulation and glycolytic flux in Ishikawa human endometrial cancer cells
Keywords: Glycolysis; Cytosolic pH regulation; Na+/H+ exchanger; NHE1; Tumor cells;
Na+/H+ exchanger in the regulation of platelet activation and paradoxical effects of cariporide
Keywords: Cariporide; EXPEDITION trial; HOE 642; Ischemia reperfusion; NHE1; Platelet aggregation
Topological analysis of the Na+/H+ exchanger
Keywords: Na+/H+ exchanger; Membrane protein; Topology model; pH regulation; BCECF-AM; 2â²,7â²-bis(2-carboxyethyl)-5(6) carboxyfluorescein-acetoxymethyl ester; CHO; Chinese hamster ovary; HA; hemagglutinin; NHE1; Na+/H+ exchanger type 1 isoform; pHi; intracellula
Calcineurin B homologous protein 3 negatively regulates cardiomyocyte hypertrophy via inhibition of glycogen synthase kinase 3 phosphorylation
Keywords: Akt; protein kinase B; ANP; atrial natriuretic peptide; CaMKII; Ca2Â +/calmodulin-dependent protein kinase II; CHP3; calcineurin B homologous protein 3; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; DMEM; Dulbecco's modified Eagle's medium; FBS;
RhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport, cytoskeletal organization and migration
Keywords: LPA; lysophosphatidic acid; NHE1; sodium hydrogen exchanger isoform 1; Rock; RhoA kinase; RSK; ribosomal S6 kinase RSK; ctNHE; C-Terminus Recombinant human NHE1.; Sodium hydrogen exchanger; NHE1; Rock kinase; Rsk; Cytoskeleton; Lysophosphatidic acid;
CIAPIN1 targets Na+/H+ exchanger 1 to mediate MDA-MB-231 cells׳ metastasis through regulation of MMPs via ERK1/2 signaling pathway
Keywords: CIAPIN1; Migration; Invasion; NHE1; MMPs; ERK1/2;
NHE1 deficiency in liver: Implications for non-alcoholic fatty liver disease
Keywords: NHE1; Steatohepatitis; Liver fibrosis; Insulin resistance; Metabolic syndrome; Obesity;
Structural determinants for the ouabain-stimulated increase in Na-K ATPase activity
Keywords: Ouabain; Blood pressure; Na-K ATPase; NHE1; Src kinase; TIRF microscopy;
Huntingtin regulates Ca2+ chemotaxis and K+-facilitated cAMP chemotaxis, in conjunction with the monovalent cation/H+ exchanger Nhe1, in a model developmental system: Insights into its possible role in Huntington׳s disease
Keywords: Huntingtin; Actin-myosin cytoskeleton; Myosin heavy chain kinase; Inositol 1,4,5-trisphosphate receptor; Cation/H+ exchanger; Calcium chemotaxis; Nhe1; Cell motility;
Structural and functional insights into the cardiac Na+/H+ exchanger
Keywords: DPC; dodecylphosphocholine; NHE1; Na+/H+ exchanger type 1 isoform; NMR; nuclear magnetic resonance; TM; transmembrane; Cation coordination; Na+/H+ exchanger; Membrane protein; Nuclear magnetic resonance; pH regulation;
The regulation of NHE1 and NHE3 activity by angiotensin II is mediated by the activation of the angiotensin II type I receptor/phospholipase C/calcium/calmodulin pathway in distal nephron cells
Keywords: Angiotensin II; CaMKII; Erk1/2; NHE1; NHE3;
Directional cell migration in an extracellular pH gradient: A model study with an engineered cell line and primary microvascular endothelial cells
Keywords: pHe; Extracellular pH; MVECs; Microvascular endothelial cells; AIAC; Actin-integrin adhesion complex; NHE1; Na+/H+ ion exchanger; Cell migration; Extracellular pH gradient; Integrin-activation; Tumor; Wound healing;
Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis
Keywords: GSK3; Hexokinase II; c-Myc; Apoptosis; Mitochondria; Benzo[a]pyrene; NHE1;
Structural and functional analysis of extracellular loop 4 of the Nhe1 isoform of the Na+/H+ exchanger
Keywords: CHO; Chinese hamster ovary; EL; extracellular loop; HA; hemagglutinin; NHE1; Na+/H+ exchanger type 1 isoform; MTSES; ([2-Sulfonatoethyl]methanethiosulfonate); MTSET; ([2-(Trimethylammonium)ethyl] methanethiosulfonate); TM; transmembrane segment; Cation co
Megakaryocyte development is normal in mice with targeted disruption of Tescalcin
Keywords: Tesc; Tescalcin gene; Tescalcin; Megakaryocyte; Platelet; Fli-1; NHE1;
Action of ANP on the nongenomic dose-dependent biphasic effect of aldosterone on NHE1 in proximal S3 segment
Keywords: ALDO; Aldosterone; ANP; atrial natriuretic peptide; BAPTA; dimethyl-BAPTA; pHi; intracellular pH; pHirr; intracellular pH recovery rate; NHE1; basolateral Na+/H+ exchanger isoform; [Ca2+]i; cytosolic free calcium concentration; ANP; Aldosterone; NHE1; Pro
Intracellular pH regulation by Na+/H+ exchanger-1 (NHE1) is required for growth factor-induced mammary branching morphogenesis
Keywords: Mammary development; Branching morphogenesis; Sodium hydrogen exchanger; NHE1; Intracellular pH; Transforming growth factor-alpha;
Identification of the critical structural determinants of the EF-hand domain arrangements in calcium binding proteins
Keywords: Ca2+; calcium; CaBPs; calcium binding proteins; CaM; calmodulin; CNB; calcineurin B; SCP; sarcoplasmic calcium binding protein; TnC; troponin C; TnI; troponin I; TnT; troponin T; Tn; troponin; hCLP; human calmodulin-like protein; CIB1; calcium and integri
Blockade of peripheral and spinal Na+/H+ exchanger increases formalin-induced long-lasting mechanical allodynia and hyperalgesia in rats
Keywords: Protons; NHE1; NHE inhibitors; Chronic pain; Secondary hyperalgesia; Secondary allodynia
Role of the spinal Na+/H+ exchanger in formalin-induced nociception
Keywords: NHE1; NHE inhibitors; Zoniporide; NHE1 like-immunoreactivity; Spinal processing;
Potential Role of NHE1 (Sodium-Hydrogen Exchanger 1) in the Cellular Dysfunction of Lactic Acidosis: Implications for Treatment
Keywords: Acidosis; pH; cell injury; Na+-H+ exchanger; NHE1; lactic acidosis; SLC9A1;
Elevated levels of activated NHE1 protect the myocardium and improve metabolism following ischemia/reperfusion injury
Keywords: NHE1; I/R injury; Cardiac metabolism;
Structural and functional analysis of critical amino acids in TMVI of the NHE1 isoform of the Na+/H+ exchanger
Keywords: BCECF-AM; 2â²,7â²-bis(2-carboxyethyl)-5(6) carboxyfluorescein-acetoxymethyl ester; DPC; dodecylphosphocholine; HA; hemagglutinin; Intracellular pH; pHi; MTSET; ([2-(Trimethylammonium)Ethyl]Methanethiosulfonate); NhaA; E. coli Na+/H+ antiporter type A; N
Intestinal transport following transfer to increased salinity in an anadromous fish (Oncorhynchus mykiss)
Keywords: Rainbow trout; Base secretion; NHE1; NHE2; SLC26a6
C/EBP ζ targets to neutrophil gelatinase-associated lipocalin (NGAL) as a repressor for metastasis of MDA-MB-231 cells
Keywords: NGAL; neutrophil gelatinase-associated lipocalin; EMT; epithelial to mesenchymal transition; ER; estrogen receptors; TSG; tumor suppressor gene; DDIT3; DNA damage-inducible transcript 3; ESCC; oesophageal squamous cell carcinoma; CM; conditioned medium; N
Regulation of cancer cell metabolism by hypoxia-inducible factor 1
Keywords: BNIP3; Glucose transporter; Glycolysis; HIF-1; Lactate dehydrogenase; MCT4; Mitochondrial autophagy; NHE1; Oxygen; PDK1; Warburg effect
Protons extruded by NHE1: Digestive or glue?
Keywords: Adhesion; Integrin; Invasion; Matrix metalloproteinases; Migration; Na+/H+ exchange; NHE1
A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells
Keywords: α-NF; α-naphthoflavone; 3-MA; 3-methyladenine; AhR; aryl hydrocabon receptor; AO; acridine orange; B[a]P; benzo[a]pyrene; BFM; bafilomycin A1; CYP1; cytochrome P450 1; DFO; desferrioxamine; DHE; dihydroethidium; DPO; deferiprone; LFR; lactoferrin; LLoMe
Human immunodeficiency virus (HIV-1) Vpr induced downregulation of NHE1 induces alteration in intracellular pH and loss of ERM complex in target cells
Keywords: HIV-1; Vpr; Apoptosis; NHE1; Intracellular pH;
The effect of acidosis on adenosine release from cultured rat forebrain neurons
Keywords: ACE; acetate; AN; adenine nucleotides; ADO; adenosine; BCECF-AM; 2â²,7â²-bis(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester; CNTs; concentrative nucleoside transporters; CNS; central nervous system; DIV; days in vitro; EIPA; 5-(N)-ethyl-N-i