Keywords: ANK; ankyrin; CADASIL; cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; CSL; CBF1, Suppressor of Hairless Lag 1; CHYS1; chondroitin sulfate synthase; Dll; Delta-like; EGF; epidermal growth factor; EOGT; EGF domai
مقالات ISI (ترجمه نشده)
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Keywords: AP-1; activator protein-1; APP; amyloid precursor protein; AICD; APP intracellular domain; DAMPs; damage associated molecular patterns; FOXO3; forkhead box O3; HES; hairy-enhancer of split; HPCs; hematopoietic progenitor cells; HDAC; histone deacetylase;
Keywords: BMS; Battery management system; CAES; Compressed air energy storage; DoD; Depth of discharge; EES; Electric energy storage; EV; Electric vehicle; GHG; Greenhouse gases; HEV; Hybrid electric vehicle; ICEV; Internal combustion engine vehicle; Li-ion; Lithiu
Keywords: LRIC; limb remote ischemic conditioning; NICD; Notch intracellular domain; α-SMA; α-smooth muscle actin; MCAO; middle cerebral artery occlusion; CBF; cerebral blood flow; PreC; ischemic pre-conditioning; PerC; ischemic per-conditioning; PostC; ischemic
Keywords: 5-FU; 5-Fluorouracil; ABCB5; ATP-binding cassette sub-family B member 5; ABCC2; ATP-binding cassette sub-family C member 2; ABCG2; ATP-binding cassette sub-family G member 2; ACs; Anthocyanins; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukemia; AP
Keywords: cAMP; Cyclic Adenosine Monophosphate; COPD; Chronic Obstructive Pulmonary Disease; CCSP; Club Cell Secretory Protein; CF; Cystic Fibrosis; EGFR; Epidermal Growth Factor Receptor; EMT; Epithelial to Mesenchymal Transition; ERK; Extracellular Signal-Regulat
Keywords: ALK1; activin receptor-like kinase1; ANG/Ang; angiopoietin; Bcl-xL; b-cell lymphoma-extra large; BM; bone marrow; BMDCs; bone marrow derived cells; BMP; bone morphogenetic protein; Bv8; bombina variagata peptide 8; CAFs; cancer/carcinoma associated fibrob
Keywords: AI; annual installed wind capacity; AGC; Automatic Generation Control; ACE; Area Control Error; ACPS1D; Average CPS1 Drop; AC; alternating current; BES; battery energy storage; CI; cumulative installed wind capacity; CDEs; CO2 emissions; CPS; control perf
Keywords: Pancreatic cancer; Angiogenesis; Vascular endothelial growth factor (VEGF); ANGPT; angiopoietin; BRAF; serine/threonine-protein kinase B-raf; CAF; cancer associated fibroblast; Cdkn2a; cyclin-dependent kinase inhibitor 2A; CI; confidence interval; CSF1R;
Keywords: EPI; expanded program on immunization; HibCV; Haemophilus influenzae type b conjugate vaccine; NICD; National Institute for Communicable Diseases; NP; nasopharyngeal; NPS; nasopharyngeal swabs; NVT; pneumococcal non-vaccine serotype; PCV; pneumococcal con
Keywords: AHA/ACCF/HRS; American Heart Association/American College of Cardiology Foundation/Heart Rhythm Society; CI; confidence interval; CRT; cardiac resynchronization therapy; ECG; electrocardiogram/electrocardiographic; HFREF; heart failure with reduced ejecti
Keywords: AV; atrioventricular; AVD; atrioventricular delay; BVP; biventricular pacing; CRT; cardiac resynchronization therapy; LBBB; left bundle branch block; LV; left ventricle/ventricular; LVdP/dtmax; maximal rate of systolic left ventricular pressure rise; LVTA
Keywords: 4NQO; 4-nitroquinoline 1-oxide; ADH; alcohol dehydrogenase; ALDH; acetaldehyde dehydrogenase; CYP2E1; cytochrome P450 2E1; Edh; EH-domain containing gene; ELOVL; very long chain fatty acid elongase; GPCRs; G-protein coupled receptors; HNE; 4-hydroxynonena
Keywords: KCs; kupffer cells; JNKs; C-Jun N-terminal kinases; MAPKs; mitogen-activated protein kinases; CCR2; C-C motif chemokine receptor 2; ATMs; Adipose tissue macrophages; HFD; high-fat diet; MLK3; mixed-lineage kinase 3; PPAR; peroxisome proliferator-activat
Keywords: ATCC; American Type Culture Collection; Bglap; bone gamma carboxyglutamate protein; BMP; bone morphogenetic protein; BSA; bovine serum albumin; CCN; Cyr61, connective tissue growth factor and Nov; CMV; cytomegalovirus; Col2.3; 2.3Â kb fragment of Col1a1;
Keywords: Aβ; amyloid β protein; NFT; neurofibrillary tangles; APP; amyloid precursor protein; PSs; presenilins; NICD; Notch intracellular domain; mTOR; mammalian Target of Rapamycin; PP2A; protein phosphatase 2; GSK-3; glycogen synthase kinase-3; CTFS; cytosol-s
The role of SIRT1 in diabetic retinopathy
Keywords: SIR2; Silent Information Regulator2; HDACs; histone deacetylaser; NAD+; nicotinamide adenine dinucleotide; DM; diabetes mellitus); AGEs; advanced glycation end products; AMPK; adenosine monophosphate-activated protein kinas; TGFβ1; transforming growth fa
Successful liver-directed gene delivery by ERCP-guided hydrodynamic injection (with videos)
Keywords: AKT; protein kinase B; CBD; common bile duct; CHD; common hepatic duct; NICD; notch intracellular domain; PCR; polymerase chain reaction; CMV-SB; pCytomegalovirus Sleep Beauty;
Molecular adjuvants that modulate regulatory T cell function in vaccination: A critical appraisal
Keywords: ADCC; antibody dependent cell cytotoxicity; CD; cluster of differentiation; mAb; monoclonal antibody; CsA; cyclosporine; CTLA-4; T-lymphocyte antigen 4; GITR; glucocorticoid-induced tumor necrosis factor receptor (TNFR) family related gene; CCR4; C-C chem
The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma
Keywords: Allergic asthma; Notch signaling; Gata3; TH2 immunity; house dust mite; recombination signal-binding protein for IgJκ region; stapled α-helical peptide derived from mastermind-like 1; BAL; Bronchoalveolar lavage; BHR; Bronchial hyperreactivity; DC; De
Maternal Consumption of High-fat Diet in Mice Alters Hypothalamic Notch Pathway, NPY Cell Population and Food Intake in Offspring
Keywords: ARC; arcuate nucleus; Ascl1; achaete-scute homolog 1; bHLH; basic helix-loop-helix; BMP; bone morphogenetic protein; BrDU; 5-bromo-2â²-deoxyuridine; BSA; bovine serum albumin; BW; body weight; Ct; comparative threshold cycle; Cy3; cyanine 3; DAB; 3,3â²-
Natural and synthetic polymers/bioceramics/bioactive compounds-mediated cell signalling in bone tissue engineering
Keywords: ALP; alkaline phosphatase; ANG; angiogenin; AuNPs; gold nanoparticles; BMP; bone morphogenetic protein; BSP; bone sialoprotein; BTE; bone tissue engineering; COL1; collagen type 1; CSL; CBF1/Su(H)/Lag-1 protein; ERK; extracellular signal-regulated kinase;
Enteroaggregative Escherichia coli is the predominant diarrheagenic E. coli pathotype among irrigation water and food sources in South Africa
Keywords: DEC; diarrheagenic E. coli; EAEC; enteroaggregative E. coli; EIEC; enteroinvasive E. coli; ETEC; enterotoxigenic E. coli; EPEC; enteropathogenic E. coli; DAEC; diffusely adherent E. coli; AIEC; adherently invasive E. coli; DMEM; Dulbecco's Modified Eagle
In silico analysis, seasonal variation and gonadotropic regulation of jag1 and its receptor notch1 in testis of spotted snakehead Channa punctatus
Keywords: DSL; Delta, Serrate and LAG2; EGF; Epidermal growth factor; hCG; Human chorionic gonadotropin; ORF; Open reading frame; RT-PCR; Reverse transcription polymerase chain reaction; qPCR; Quantitative polymerase chain reaction; ANOVA; Analysis of variance; TMD
Maintenance of hematopoietic stem and progenitor cells in fetal intra-aortic hematopoietic clusters by the Sox17-Notch1-Hes1 axis
Keywords: AGM; aorta-gonad-mesonephros; HSCs; hematopoietic stem cells; HPCs; hematopoietic progenitor cells; IAHCs; intra-aortic hematopoietic clusters; Sox; Sry-related high mobility group box; NICD; Notch intra-cellular domain; SCF; stem cell factor; IL; interle
ERK regulates mitochondrial membrane potential in fission deficient Drosophila follicle cells during differentiation
Keywords: PFC; Posterior Follicle Cells; EGFR; Epidermal Growth Factor Receptor; NICD; Notch Intra-Cellular Domain; ROS; Reactive Oxygen Species; ETC; Electron Transport Chain; Ψm; Mitochondrial Membrane Potential; Mitochondria; Signaling; Drosophila; ERK; Notch;
Notch as a Driver of Gastric Epithelial Cell Proliferation
Keywords: Stomach; Homeostasis; Gastric Stem Cells; Gastric Cancer; ADAM10; a disintegrin and metalloproteinase 10; GC; gastric cancer; GI; gastrointestinal; GSI; γ-secretase inhibitor; NICD; Notch receptor intracellular domain; TX; tamoxifen;
Inhibition of miR-363 protects cardiomyocytes against hypoxia-induced apoptosis through regulation of Notch signaling
Keywords: miRNAs; microRNAs; FBS; fetal bovine serum; RT-qPCR; real-time quantitative polymerase chain reaction; LDH; lactate dehydrogenase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NICD; Notch intracellular domain; UTR; untranslated regio
Inhibition of Notch signalling has ability to alter the proximal and distal TCR signalling events in human CD3+ αβ T-cells
Keywords: TCR; T cell receptor; Dll; delta-like ligand; GSI-X; γ-secretase inhibitor; HES1; hairy enhancer of split1; IFN-γi; nterferon-γ; NICD; Notch intracellular domain; Jag; jagged; NRARP; Notch-regulated ankyrin repeat protein; αβ T cells; T cell anergy;
Risperidone ameliorates cognitive deficits, promotes hippocampal proliferation, and enhances Notch signaling in a murine model of schizophrenia
Keywords: DG; dentate gyrus; MRI; magnetic resonance imaging; NICD; Notch intracellular fragment; NMDA; N-methyl-d-aspartate; NSCs; neural stem cells; PCP; phencyclidine; Rip; risperidone; SGZ; subgranular zone; shRNA; short hairpin RNA; Hippocampus; Notch; Risperi
Inscuteable maintains type I neuroblast lineage identity via Numb/Notch signaling in the Drosophila larval brain
Keywords: Drosophila larval brain neuroblasts (NBs); Inscuteable (Insc); NB lineage maintenance; Type I and type II NBs; Numb/Notch signaling; Ase; Asense; Dpn; Deadpan; Erm; Earmuff; GMCs; ganglion mother cells; INPs; intermediate neural progenitors; Insc; Inscute
Emerin suppresses Notch signaling by restricting the Notch intracellular domain to the nuclear membrane
Keywords: CSL; CBF1/suppressor hairless/Lag-1; NEXT; Notch1 extracellular truncation; NICD; Notch intracellular domain; ADAM; A disintegrin and metalloproteinase; CoA; Coactivators; CoR; Corepressors; PM; Plasma membrane; NE; Nuclear envelope; NGPS; Néstor-Guiller
The metalloproteinase ADAM10: A useful therapeutic target?
Keywords: APL; Acute Promyelocytic Leukemia; ADAM; A Disintegrin And Metalloproteinase; AP2; Adaptor Protein-2; AD; Alzheimer's Disease; Aβ; Amyloid beta; APP; Amyloid Precursor Protein; ACE; Angiotensin Converting Enzyme; APRIL; A Proliferation-Inducing Ligand; B
Redox signaling in the gastrointestinal tract
Keywords: HNE; 4-hydroxynonenal; 8-OHdG; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; AP-1; Activator protein 1; APC; Adenomatous polyposis coli; APE-1; Apurinic/apyrimidinic endonuclease 1; Math1; Atonal homolog 1; Bax; BCL2-associated X protein; β-TrCP; Beta-transduci
Stroma-induced Jagged1 expression drives PC3 prostate cancer cell migration; disparate effects of RIP-generated proteolytic fragments on cell behaviour and Notch signaling
Keywords: Invasion; Jagged1; Metastasis; Migration; Notch signaling; Prostate cancer; ADAM; A disintegrin and metalloproteinase; BMECs; bone marrow endothelial cells; BMS; bone marrow stroma; Dll; Delta-like ligand; FL-Jag; full-length Jagged; JCTF; Jagged1 C-termi
DLL4+ dendritic cells: Key regulators of Notch Signaling in effector T cell responses
Keywords: APC; antigen presenting cell; CTL; cytotoxic T lymphocyte; DC; dendritic cell; cDC; conventional dendritic cell; pDC; plasmacytoid dendritic cell; CMP; common myeloid progenitor; HPC; hematopoietic progenitor cell; MDP; macrophage and DC progenitor; HSCT;
The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development
Keywords: BLPD; B-cell lymphoproliferative disease; EtOH; ethanol; HF; hair follicle; LICD; ligand intracellular domain; msx2LOF; Msx2-Cre+/tg-mediated loss of function; NICD; Notch intracellular domain; N1VG; hypomorphic Notch1 allele; PSmsx2LOF; Preselin1 and Pre
Lack of galectin-3 increases Jagged1/Notch activation in bone marrow-derived dendritic cells and promotes dysregulation of T helper cell polarization
Keywords: Th; T helper; WT; wild-type; Lgals3â/â; galectin-3-deficient mice; BMDC; bone marrow-derived dendritic cell; DCs; dendritic cells; NICD; Notch intracellular domain; APC; antigen presenting cell; Treg; T regulatory cell; qPCR; quantitative polymerase c
Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression
Keywords: cardiac precursor cells; differentiation; heart disease; lncRNAs; miRNAs; NOTCH; CARMEN; (CAR)diac (M)esoderm (E)nhancer-associated (N)oncoding RNA; CPC; cardiac precursor cell; DLL1; Delta-like1; GO; gene ontology; J1; Jagged1; lncRNA; long noncoding RNA
Evaluation of the expression and function of the P2X7 receptor and ART1 in human regulatory T-cell subsets
Keywords: ART1; ADP-ribosyltransferases 1; ART2; ADP-ribosyltransferases 2; ART5; ADP-ribosyltransferases 5; ATP; adenosine tri-phosphate; CFSE; carboxyfluorescein succinimidyl ester; H2O2; hydrogen peroxide; iTreg; inducible regulatory T cells; NAD; nicotinamide a
Targeting cancer stem cells in solid tumors by vitamin D
Keywords: CSC; Cancer stem cell; 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; EpCAM; Epithelial cell adhesion molecule; PROM1; Prominin 1; CXCR4; C-X-C chemokine receptor type 4; SDF1; Stromal cell-derived factor 1; ALDH-1; Aldehyde dehydrogenease-1; EMT; Epithelial-
Receptor channel TRPC6 orchestrate the activation of human hepatic stellate cell under hypoxia condition
Keywords: Hepatic stellate cells; TRPC6; Hypoxia; NICD;
NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium
Keywords: CAVD; calcific aortic valve disease; ALP; alkaline phosphatase; IBSP; bone sialoprotein; SPARC; osteonectin; TGFβ; transforming growth factor beta; WNT; wingless-type MMTV integration site family; CSL; suppressor of hairless; MAML; mastermind-like protei
The Notch intracellular domain represses CRE-dependent transcription
Keywords: CREB; NICD; PKA; Alzheimer's disease; Memory;
Frequent mutations in NOTCH1 ligand-binding regions in Japanese oral squamous cell carcinoma
Keywords: OSCC; oral squamous cell carcinoma; HNSCC; head and neck squamous cell carcinoma; NECD; NOTCH extracellular domain; NICD; NOTCH intracellular domain; TALL; T-cell acute lymphoblastic leukemia; EGF; epidermal growth factor; T stage; tumor stage; N stage; l
Co-culturing improves the OGD-injured neuron repairing and NSCs differentiation via Notch pathway activation
Keywords: OGD; oxygen-glucose deprivation; NSCs; neural stem cells; NICD; Notch intra-cellular domain; Hes; hairy enhancer of split; MAP-2; microtubule-associated protein 2; GFAP; glial fibrillary acidic protein; BSA; albumin from bovine serum; DAPT; N-[N-(3,5-difl
Clinical Application of Basic ScienceNotch signaling and new therapeutic options in liver disease
Keywords: Jag-1; Jagged-1; Dll; Delta-like; NICD; Notch intracellular domain; RBP-Jκ; recombination signal binding protein immunoglobulin kappa J; MAML1; mastermind-like 1; Hes1; hairy enhancer of split-1; Hey1; hairy enhancer of split-related with YRPW motif1; So
The Notch γ-secretase inhibitor ameliorates kidney fibrosis via inhibition of TGF-β/Smad2/3 signaling pathway activation
Keywords: Kidney fibrosis; Epithelial-to-mesenchymal transition; Fibroblast; Notch; TGF-β; DBZ; dibenzazepine; UUO; unilateral ureteral obstruction; NICD; Notch intracellular domain; ICN; intracellular domain of Notch; TECs; tubular epithelial cells; ECM; extracel
Reelin, neuronal polarity and process orientation of cortical neurons
Keywords: Apoer2; apolipoprotein E receptor 2; BDNF; brain-derived neurotrophic factor; cp; cortical plate; Dab1; disabled-1; EBs; end-binding proteins; ECM; extracellular matrix; GEF; Guanine nucleotide exchange factor; imz; intermediate zone; IPCs; intermediate p
Molecular cross talk between Notch1, Shh and Akt pathways during erythroid differentiation of K562 and HEL cell lines
Keywords: NICD; Notch1 intracellular domain; Shh; Sonic Hedgehog; GSI; Gamma secretase inhibitor; DNCSL; Dominant negative CSL; Ptch1; Patched1; Smo; Smoothened; myr-Akt; myristoylated-Akt; Gli; Glioma-associated oncogene homologue; Notch1; Erythropoiesis; Shh; Akt