Keywords: نیمزولید; Nimesulide; 1,2,3-Triazole; Azide; Alkyne; Anticancer activity;
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Keywords: نیمزولید; Bisphosphonate-associated osteonecrosis of the jaw; Anti-inflammatory agents; Dexamethasone; Nimesulide;
Keywords: نیمزولید; inclusion complexes; high amylose; nimesulide; praziquantel; controlled release; solid state NMR; X-ray diffractometry; calorimetry (DSC); dissolution;
Keywords: نیمزولید; analgesia; third molar; nimesulide; ketoprofen; split-mouth
Keywords: نیمزولید; Yulangsan polysaccharide; Nimesulide; Hepatoprotection;
Keywords: نیمزولید; BIA-MPA; batch injection analysis with multiple pulse amperometric detection; BDD; boron-doped diamond; NIM; nimesulide; PAR; paracetamol; FIA; flow injection analysis; Batch injection analysis (BIA); Flow injection analysis (FIA); Unmodified boron-doped
Keywords: نیمزولید; ALP; alkaline phosphatase; ALT; alanine aminotransferase; ANIT; 1-naphthylisothiocyanate; APAP; acetaminophen; AST; aspartate aminotransferase; BDZ; bendazac; CBZ; carbamazepine; CCL4; carbon tetrachloride; CSA; cyclosporine A; CZS; chlorzoxasone; DILI; d
Electrochemical characterization of a novel nimesulide anti-inflammatory drug analog: LQFM-091
Keywords: نیمزولید; Nimesulide; Butylhydroxytoluene; Novel drugs; Electroanalysis; Electrochemical characterization;
The nitro-reduced metabolite of nimesulide: Crystal structure, spectroscopic characterization, ESI-QTOF mass spectrometric analysis and antibacterial evaluation
Keywords: نیمزولید; Crystal structure; Nimesulide; Metabolite; NMR; MS; Antibacterial activity;
Optimization of nimesulide oxidation via a UV-ABC/H2O2 treatment process: Degradation products, ecotoxicological effects, and their dependence on the water matrix
Keywords: نیمزولید; UV-ABC/H2O2 treatment process; Nimesulide; Effluent organic matter; Ecotoxicity; Degradation pathways;
Determination of piroxicam and nimesulide using an electrochemical sensor based on reduced graphene oxide and PEDOT:PSS
Keywords: نیمزولید; Reduced graphene oxide; PEDOT:PSS; Piroxicam; Nimesulide; Individual and simultaneous detection;
Enhanced performance of a metal-organic framework analogue to MIL-101(Cr) containing amine groups for ibuprofen and nimesulide controlled release
Keywords: نیمزولید; Controlled drug release; MIL-101(Cr); Ibuprofen; Nimesulide
Electro-oxidation of nimesulide at 5% barium-doped zinc oxide nanoparticle modified glassy carbon electrode
Keywords: نیمزولید; Nimesulide; Voltammetry; 5% Barium-doped zinc oxide nano particles; Oxidation; Drug analysis
Synthesis, spectroscopic characterization, crystallographic studies and antibacterial assays of new copper(II) complexes with sulfathiazole and nimesulide
Keywords: نیمزولید; Metal complexes; Sulfathiazole; Nimesulide; Copper(II); Antibacterial agentsbipy, 2,2′-bipyridine; CFU, colony-forming units; Cu-NMS, copper(II) complex with nimesulide and bipyridine; Cu-SFT, copper(II) complex with sulfathiazole and bipyridine; DMSO, di
Formation of PVP/nimesulide microspheres by supercritical antisolvent coprecipitation
Keywords: نیمزولید; Nanocomposite microparticles; Coprecipitation; Nimesulide; Polyvinylpyrrolidone; Supercritical antisolvent process; Precipitation mechanisms
Simultaneous determination of nimesulide and its four possible metabolites in human plasma by LC–MS/MS and its application in a study of pharmacokinetics
Keywords: نیمزولید; Nimesulide; Metabolites; LC–MS/MS; Pharmacokinetics
COX-2 plays a role in angiogenic DBA+ uNK cell subsets activation and pregnancy protection in LPS-exposed mice
Keywords: نیمزولید; Uterine natural killer; Dolichos Biflorus agglutinin lectin; Cyclooxygenase; Nimesulide; Inflammation; LPS;
Isomeric iodinated analogs of nimesulide: Synthesis, physicochemical characterization, cyclooxygenase-2 inhibitory activity, and transport across Caco-2 cells
Keywords: نیمزولید; Nimesulide; COX-2; Iodine; Caco-2 cell monolayers; Lipophilicity; Blood-brain barrier;
Electrochemical oxidation of nimesulide in aqueous acid solutions based on TiO2 nanostructure modified electrode as a sensor
Keywords: نیمزولید; Drug analysis; Heterogeneous rate constant; Nimesulide; Oxidation; Titanium dioxide nanoparticles;
Isomeric methoxy analogs of nimesulide for development of brain cyclooxygense-2 (COX-2)-targeted imaging agents: Synthesis, in vitro COX-2-inhibitory potency, and cellular transport properties
Keywords: نیمزولید; Nimesulide; Methoxy substituted analog; COX-2; Caco-2 cells
Attenuation of renovascular hypertension by cyclooxygenase-2 inhibitor partly through ANP release
Keywords: نیمزولید; Cyclooxygenase; Renal hypertension; Nimesulide; NS-398; ANP; Angiotensin
Development and validation of a novel RP-HPLC method for simultaneous determination of paracetamol, phenylephrine hydrochloride, caffeine, cetirizine and nimesulide in tablet formulation
Keywords: نیمزولید; Phenylephrine; Paracetamol; Caffeine; Cetirizine; Nimesulide; HPLC–DAD
Nimesulide inhibits the growth of human esophageal carcinoma cells by inactivating the JAK2/STAT3 pathway
Keywords: نیمزولید; Nimesulide; Esophageal carcinoma cells; JAK2/STAT3; Survivin; Caspase-3;
Copper(II) ion as modulator of the conformation of non-steroidal anti-inflammatory drugs. Theoretical insight into the structure
Keywords: نیمزولید; Phenylobutazone; Nimesulide; Diclofenac; Meloxicam; Cu2+
Protective effect of nimesulide against hepatic ischemia/reperfusion injury in rats: Effects on oxidant/antioxidants, DNA mutation and COX-1/COX-2 levels
Keywords: نیمزولید; Rat; Liver; Oxidant/antioxidant; Nimesulide
Synthesis of 2,2,4-trimethyl-1,2-dihydroquinolinyl substituted 1,2,3-triazole derivatives: Their evaluation as potential PDE 4B inhibitors possessing cytotoxic properties against cancer cells
Keywords: نیمزولید; Nimesulide; 1,2,3-Triazole; Cycloaddition; PDE4B; Cytotoxic activities
Drug delivery investigations of quaternised poly(propylene imine) dendrimer using nimesulide as a model drug
Keywords: نیمزولید; Poly(propylene imine) dendrimer; Drug carrier; Nimesulide; Solubility; In vitro release; Cytotoxicity;
Nimesulide binding site in the B0AT1 (SLC6A19) amino acid transporter. Mechanism of inhibition revealed by proteoliposome transport assay and molecular modelling
Keywords: نیمزولید; C12E8, octaethylene glycol monododecyl ether; NS-398, N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamideTransport; Liposome; Amino acids; Nimesulide; Drugs; Molecular dockingNimesulide (PubChem CID: 4495); NS398 (PubChem CID: 4553); Omeprazole (PubChem
Motor learning in common marmosets: Vestibulo-ocular reflex adaptation and its sensitivity to inhibitors of Purkinje cell long-term depression
Keywords: نیمزولید; Cerebellum; Cyclooxygenase; Long-term potentiation; Nimesulide; T-588;
N-(3-Arylaminopyridin-4-yl)alkanesulfonamides as pyridine analogs of nimesulide: Cyclooxygenases inhibition, anti-inflammatory studies and insight on metabolism
Keywords: نیمزولید; Nimesulide; COXs inhibitors; Nonsteroidal anti-inflammatory drugs; λ carrageenan-induced pleurisy; NSAIDs; nonsteroidal anti-inflammatory drugs; COX; cyclooxygenase; PGs; prostaglandins; TXA2; thromboxane A2; PGI2; prostacyclin; NO; nitric oxide; H2S; hy
Synthesis and biological evaluation of nimesulide based new class of triazole derivatives as potential PDE4B inhibitors against cancer cells
Keywords: نیمزولید; Nimesulide; 1,2,3-Triazole; Cycloaddition; PDE4B; Cytotoxic activities;
Are drug provocation tests still necessary to test the safety of COX-2 inhibitors in patients with cross-reactive NSAID hypersensitivity?
Keywords: نیمزولید; Drug hypersensitivity; Drug provocation tests; Alternative drugs; Nimesulide; Meloxicam; Aspirin hypersensitivity; Aspirin intolerance; NSAID cross-reactivity; Predictive factors;
Rapeseed oil-rich diet alters in vitro menadione and nimesulide hepatic mitochondrial toxicity
Keywords: نیمزولید; Toxicology; Diet; Menadione; Nimesulide; Mitochondria; Membranes
Induction of apoptosis and inhibition of cell proliferation by the cyclooxgenase enzyme blocker nimesulide in the Ishikawa endometrial cancer cell line
Keywords: نیمزولید; Nimesulide; COX-2; Endometrial cancer; Cytotoxicity; Apoptosis
Thermosensitive and mucoadhesive in situ gel based on poloxamer as new carrier for rectal administration of nimesulide
Keywords: نیمزولید; Nimesulide; In situ gel; Mucoadhesive polymer; Thermosensitive; Rectal drug delivery
FT-NIR spectroscopy for rapid and simple determination of nimesulide in rabbit plasma for pharmacokinetic analysis
Keywords: نیمزولید; Pharmacokinetics; Bio-availability; FT-NIR; Nimesulide; Rabbit
Nimesulide adsorbed on silica aerogel using supercritical carbon dioxide
Keywords: نیمزولید; Silica aerogel; Adsorption; Nimesulide; Drug delivery systems; Adsorption mechanisms;
From COX-2 inhibitor nimesulide to potent anti-cancer agent: Synthesis, in vitro, in vivo and pharmacokinetic evaluation
Keywords: نیمزولید; COX-2 inhibitor; Nimesulide; Anti-cancer; Xenograft; Pharmacokinetics
Novel 1-alkynyl substituted 1,2-dihydroquinoline derivatives from nimesulide (and their 2-oxo analogues): A new strategy to identify inhibitors of PDE4B
Keywords: نیمزولید; Nimesulide; 1,2-Dihydroquinoline; Alkyne; PDE4
Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76
Keywords: نیمزولید; COX-2; Nimesulide; JCC76; Biotin; Probe;
Micellization and solubilization of a model hydrophobic drug nimesulide in aqueous salt solutions of Tetronic® T904
Keywords: نیمزولید; Tetronics®; CMT; Nimesulide; Solublization; Dynamic light scattering (DLS);
Study of nimesulide and its determination using multiwalled carbon nanotubes modified glassy carbon electrodes
Keywords: نیمزولید; Nimesulide; Multiwalled carbon nanotubes; Nafion; Modified electrode; Electrochemical behavior
Effects of Aspirin and Nimesulide on tissue damage in diabetic rats
Keywords: نیمزولید; Diabetes; Aspirin; Nimesulide; Rat
Multivariate control charts based on net analyte signal and near infrared spectroscopy for quality monitoring of Nimesulide in pharmaceutical formulations
Keywords: نیمزولید; Nimesulide; Multivariate control charts; NAS
Nimesulide improves the disease modifying anti-rheumatic profile of methotrexate in mice with collagen-induced arthritis
Keywords: نیمزولید; Methotrexate; Nimesulide; Rheumatoid arthritis; Collagen-induced arthritis;
The attenuation of pain behaviour and serum interleukin-6 concentration by nimesulide in a rat model of neuropathic pain
Keywords: نیمزولید; Nimesulide; Hyperalgesia; Allodynia; Interleukin-6; Neuropathic pain;
Interaction of nimesulide, a cyclooxygenase-2 inhibitor, with cisplatin in normotensive and spontaneously hypertensive rats
Keywords: نیمزولید; Cisplatin; Nimesulide; Cyclooxygenase-2; Nephrotoxicity; Renal blood flow; SHR
Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats
Keywords: نیمزولید; COX, cyclooxygenase; LPO, lipid peroxidation; NMDAr, N-methyl-d-aspartate receptors; QA, quinolinic acid; ROS, reactive oxygen speciesCyclooxygenase; Mitochondria; Nimesulide; Oxidative stress; Quinolinic acid; Rofecoxib
Inhibition of cyclooxygenase-2 and EP1 receptor antagonism reduces human colonic longitudinal muscle contractility in vitro
Keywords: نیمزولید; Colonic; COX-2; Diclofenac; Prostamide; Nimesulide; SC19220
Influence of the microwave technology on the physical–chemical properties of solid dispersion with Nimesulide
Keywords: نیمزولید; Microwaves; Solid dispersions; Nimesulide; Gelucire® 50/13; Lutrol® F 68; Physico-chemical characterization