دانلود مقالات ISI درباره P62 + ترجمه فارسی

Subcellular distribution of the 18 kDa translocator protein and transcript variant PBR-S in human cells

Keywords: 4E-T; eukaryotic translation initiation factor 4E nuclear import factor 1; BJ; human fibroblast cells; cDNA; DNA complementary to RNA; DCP1A; decapping mRNA 1A; DMEM; Dulbecco's modified Eagle's medium; eIF3η; eukaryotic translation initiation factor 3 s

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity

Keywords: p62/Sqstm1; p62; phosphorylated-p62; p-p62; protein-protein interaction; PPI; nuclear factor erythroid 2 related factor-2; Nrf2; Kelch-like ECH-associated protein 1; Keap1; human hepatocellular carcinoma; HCC; cerium ammonium nitrite; CAN; fluorescent pol

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis

Keywords: AST; Astemizole; HIS; Histamine; H1R; Histamine H1 receptor; ROS; Reactive oxygen species; ER; Endoplasmic reticulum; PERK; Protein kinase R-like endoplasmic reticulum kinase; IRE1α; Inositol-requiring enzyme 1; ATF; Activating transcription factor; JNK;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

High mTORC1 signaling is maintained, while protein degradation pathways are perturbed in old murine skeletal muscles in the fasted state

Keywords: Aging; Muscle; mTORC1; Autophagy; p62; Protein degradation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction

Keywords: aging; autophagy; circulating miRNA; MiR-22; p62; Atg; autophagy-related gene; FACS; fluorescence-activated cell sorting; GFP; green fluorescent protein; LNA; locked nucleic acid; MI; myocardial infarction;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Atg5-dependent autophagy plays a protective role against methylmercury-induced cytotoxicity

Keywords: Methylmercury; Autophagy; LC3; p62; Atg5;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis

Keywords: NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH associated protein 1; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling; MTT; 3-(4,5-di

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism

Keywords: ARE; antioxidant response element; ATP; adenosine triphosphate; 5-hmC; hydroxymethylcytosine; ATG; AuTophaGy related; BNIP; Bcl-2/adenovirus E18 19-kDa-interacting protein; Drp1; dynamin related protein 1; EpRE; electrophile response element; eNOS; endoth

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2016 سفارش ترجمه

p62/SQSTM1 analysis in frontotemporal lobar degeneration

Keywords: p62; SQSTM1; C9orf72; Frontotemporal lobar degeneration; FTLD;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells

Keywords: Autophagy; LC3; p62; SQSTM1; Autophagic flux; Immunoblotting;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1

Keywords: PF-4708671; p70 ribosomal S6 kinase 1 (S6K1); p62; Autophagy; Nuclear factor erythroid 2-related factor 2 (Nrf2); Kelch-like ECH-associated protein 1 (Keap1); GSTA1; glutathione S-transferase A1; Keap1; Kelch-like ECH-associated protein 1; MEF; mouse embr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

p62 regulates CD40-mediated NFκB activation in macrophages through interaction with TRAF6

Keywords: p62; CD40; CD40L; TRAF6;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Tyrosine kinase inhibitor tyrphostin AG490 triggers both apoptosis and autophagy by reducing HSF1 and Mcl-1 in PEL cells

Keywords: STAT3; Signal Transducer and Activator of Transcription 3 (gene); HSF1; Heat Shock Transcription Factor 1; HSP70; Heat Shock Protein 70; Mcl-1; Myeloid Cell Leukemia 1; LC3; Microtubule-Associated protein 1 light chain 3; p62; Sequestosome1/SQSTM1; PEL; P

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Impact of nuclear factor erythroid-derived 2–like 2 and p62/sequestosome expression on prognosis of patients with gliomas

Keywords: Gliomas; Nrf2; p62; Survival; Prognosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

RIPK3 regulates p62-LC3 complex formation via the caspase-8-dependent cleavage of p62

Keywords: UBA domain; ubiquitin-associated domain; LIR; LC3-interacting region; LRS; LC3 recognition sequence; PLA; proximity ligation assay; TNT; in vitro translation; RIPK3; Necroptosis; Autophagy; p62; LC3; Caspase-8;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Levels of metacaspase1 and chaperones related to protein quality control in alcoholic and nonalcoholic steatohepatitis

Keywords: Protein quality control; Alcoholic steatohepatitis; Nonalcoholic steatohepatitis; Mca1; Hsp104; Hsp40; Ydj1; Ssa1; VCP/p97; p62; ERAD; IPOD; JUNQ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Routine Western blot to check autophagic flux: Cautions and recommendations

Keywords: Autophagy; Western blotting; Lysis buffer; LC3; p62

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Heroin abuse exaggerates age-related deposition of hyperphosphorylated tau and p62-positive inclusions

Keywords: Aging; α-Synuclein; Heroin; Neuropathology; Opiate; Tau; TDP-43; p62;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Exploring new pathways of neurodegeneration in ALS: The role of mitochondria quality control

Keywords: ALS; Mitochondria; Mitophagy; SOD1; Parkin; p62

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The autophagy pathway maintained signaling crosstalk with the Keap1-Nrf2 system through p62 in auditory cells under oxidative stress

Keywords: Autophagy; Auditory cell; Oxidative stress; p62; Keap1/Nrf2;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice

Keywords: Caspase-6; YAC128; Huntington Disease; Autophagy; p62;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation

Keywords: 3-Methyladenine (Pubmed CID 1673); Camptothecin (Pubmed CID 24360); Etoposide (Pubmed CID 36462); 7-Bromoindirubin-3-oxime (Pubmed CID 11846148); Necrostatin-1 (Pubmed CID 282833); Q-VD-OPh (Pubmed CID 11237609); 2-Phenylethynesulfonamide (Pubmed CID 3276

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1

Keywords: Sesn; sestrin; ROS; reactive oxygen species; Prx; peroxiredoxin; Srx; sulfiredoxin; ERK; extracellular signal-regulated kinase; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; mTORC1; mechanistic target of ra

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

Axonal protection by modulation of p62 expression in TNF-induced optic nerve degeneration

Keywords: p62; Rapamycin; Autophagy; Tumor necrosis factor; Optic nerve;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Dissection of the role of p62/Sqstm1 in activation of Nrf2 during xenophagy

Keywords: Autophagy; p62; Nrf2; Keap1; Xenophagy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Functional proteomics revealed IL-1β amplifies TNF downstream protein signals in human synoviocytes in a TNF-independent manner

Keywords: Synoviocytes; IL-1β; Proteomics; TNF-independent; p62;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Oxidative stress-induced autophagy: Role in pulmonary toxicity

Keywords: Autophagy; Oxidative stress; Pulmonary toxicants; Cytotoxicity; Lung injury; p62

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

LC3B is indispensable for selective autophagy of p62 but not basal autophagy

Keywords: GABARAP; gamma-aminobutyrate receptor-associated protein; GEC-1; glandularepithelial cell protein 1; GATE-16; golgi-associated ATPase enhancer of 16 kDa; ITC; isothermal titration calorimetry; LC3; microtubule-associated protein 1 light chain 3/MAP1LC3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy proteins in prostate cancer: Relation with anaerobic metabolism and Gleason score1

Keywords: Autophagy; LC3A; LC3B; p62; LDH5; Prostate cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Paget disease of bone-associated UBA domain mutations of SQSTM1 exert distinct effects on protein structure and function

Keywords: Sequestosome 1; SQSTM1; p62; Paget disease of bone; NF-κB; Ubiquitin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding

Keywords: aPKC; atypical protein kinase C; cAMP; cyclic AMP-dependent protein kinase; LC3; microtubule-associated protein 1A/B light chain 3; MEK; mitogen-activated protein kinase kinase/ERK kinase; MEKK; MEK kinase; NBR; neighbour of BRCA1 gene 1 protein; NF-κB;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of C1-Ten protein tyrosine phosphatase by p62/SQSTM1-mediated sequestration and degradation

Keywords: C1-Ten; Tensin2; p62; Sequestosome; Degradation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

SQSTM1 mutations - Bridging Paget disease of bone and ALS/FTLD

Keywords: ALS; amyotrophic lateral sclerosis; aPKC; atypical protein kinase C; C9orf72; chromosome 9 open reading frame 72; FTD; frontotemporal dementia; FTLD; frontotemporal lobar degeneration; FUS/TLS; fused in sarcoma/translocated in liposarcoma; GWAS; genome-wi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

p62 provides dual cytoprotection against oxidative stress in the retinal pigment epithelium

Keywords: Autophagy; Aging; Nrf2; Oxidative stress; p62;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity

Keywords: Mitochondrial integrity; Oxidative stress; p62; TFAM; Mitochondrial import;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Loss of CB1 receptors leads to decreased cathepsin D levels and accelerated lipofuscin accumulation in the hippocampus

Keywords: Endocannabinoid system; Hippocampus; Oxidative stress; LC3; p62; Autophagy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Distinct roles of the R3H and RRM domains in poly(A)-specific ribonuclease structural integrity and catalysis

Keywords: ANS; 1-anilinonaphtalene-8-sulfonate; CD; circular dichroism; CTD; C-terminal domain; DTT; dithiothreitol; IPTG; isopropyl-1-thio-β-d-galactopyranoside; PARN; poly(A)-specific ribonuclease; p74; the full length PARN; p62; the N-terminal fragment of PARN

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of LRRK2 kinase activity stimulates macroautophagy

Keywords: LRRK2; Leucine Rich Repeat Kinase 2; mTOR; Mammalian target of rapamycin; ROC; Ras of Complex Proteins; COR; C-terminal of ROC domain; SDS; Sodium dodecyl sulphate; EDTA; Ethylene di-ammonium tetra acetic acid; DPBS; Dulbecco's phosphate buffered saline;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Ubiquitin receptors and protein quality control

Keywords: Ubiquitin; Proteasome; Ubiquilin; p62; Autophagy;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Sequestosome1/p62: A regulator of redox-sensitive voltage-activated potassium channels, arterial remodeling, inflammation, and neurite outgrowth

Keywords: AP-1; activator protein-1; ARE; antioxidant response element; CDK; cyclin-dependent kinase; EGF; epidermal growth factor; ERK1/2; extracellular regulated kinase 1/2; HNE; 4-hydroxynonenal; HO-1; heme oxygenase-1; IL-1; interleukin-1; Keap1; Kelch-like ECH

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Reduced expression of SM22 is correlated with low autophagy activity in human colorectal cancer

Keywords: SM22; Autophagy; p62; Colorectal cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Dual inhibitor of phosphoinositide 3-kinase/mammalian target of rapamycin NVP-BEZ235 effectively inhibits cisplatin-resistant urothelial cancer cell growth through autophagic flux

Keywords: Mammalian target of rapamycin; Phosphoinositide 3-kinase; LC3-II; P62; Urothelial cancer; Cisplatin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Autophagy-related proteins (p62, NBR1 and LC3) in intranuclear inclusions in neurodegenerative diseases

Keywords: Autophagy; Intranuclear inclusions; LC3; NBR1; p62; Ubiquitin;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

p62: a versatile multitasker takes on cancer

Keywords: p62; sequestosome1; NF-κB; NRF2; mTORC1; atypical PKCs; cancer; autophagy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Metabolic contribution of hepatic autophagic proteolysis: Old wine in new bottles

Keywords: Autophagy; Lysosome; Liver; p62; Amino acid; Gluconeogenesis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

Keywords: AD; Alzheimer's disease; AKT; protein kinase B; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor; aPKC; atypical protein kinase C; APP; amyloid-β precursor protein; ATG; AuTophaGy-related; BDNF; brain-derived neurotrophic factor; C/EBP; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

West Nile virus growth is independent of autophagy activation

Keywords: Flavivirus; West Nile virus; Autophagy; Neuron; Viral encephalitis; p62;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The small molecule inhibitor PR-619 of deubiquitinating enzymes affects the microtubule network and causes protein aggregate formation in neural cells: Implications for neurodegenerative diseases

Keywords: Deubiquitinating enzymes; Oligodendroglia; p62; Heat shock proteins; Microtubules; Tau protein

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Formation of distinct inclusion bodies by inhibition of ubiquitin-proteasome and autophagy-lysosome pathways

Keywords: Inclusion body; Ubiquitin; Autophagy; p62; Proteasome; Lysosome;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Triage of oxidation-prone proteins by Sqstm1/p62 within the mitochondria

Keywords: p62; Mitochondria; Chaperone; Oxidation; Electron transport

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه