دانلود مقالات ISI درباره Pgd2 + ترجمه فارسی

PGD2 DP1 receptor stimulation following stroke ameliorates cerebral blood flow and outcomes

Keywords: CBF; cerebral blood flow; LDF; laser-Doppler flowmetry; MCA; middle cerebral artery; MCAO; middle cerebral arterial occlusion; NMDA; N-methyl-d-aspartate; PGD2; prostaglandin D2; tPA; tissue plasminogen activator; TTC; 2,3,5-triphenyl-tetrazolium chloride

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Increased ILC2s in the eosinophilic nasal polyp endotype are associated with corticosteroid responsiveness

Keywords: Dex; Dexamethasone; IL-5; Interleukin-5; IL-13; Interleukin-13; IL-25; Interleukin-25; IL-33; Interleukin-33; ILC2; Group 2 innate lymphoid cell; LTD4; Leukotriene D4; PBS; Phosphate buffered saline; PGD2; Prostaglandin D2; TSLP; Thymic stromal lymphopoie

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Anti-inflammatory actions of Chemoattractant Receptor-homologous molecule expressed on Th2 by the antagonist MK-7246 in a novel rat model of Alternaria alternata elicited pulmonary inflammation

Keywords: A. alternata; Alternaria alternata; OVA; Ovalbumin; Th2; Type 2 helper cells; CRTH2; Chemoattractant Receptor-homologous molecule expressed on Th2 cells; MK-7246; {(7R)-7-[[(4-fluorophenyl)sulfonyl](methyl)amino]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Research reportEffects of neonatal treatment with the TRPV1 agonist, capsaicin, on adult rat brain and behaviour

Keywords: TRPV1; Capsaicin; Neonatal rat; Methylnicotinate; Prepulse inhibition; Schizophrenia; PGD2; prostaglandin D2; PPI; prepulse inhibition; TRPV1; transient receptor potential vanilloid 1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanisms of allergy and clinical immunologyMastocytosis associated with a rare germline KIT K509I mutation displays a well-differentiated mast cell phenotype

Keywords: KIT; K509I; mastocytosis; germline; mast cells; well differentiated; EM; Electron microscopy; FITC; Fluorescein isothiocyanate; HuMC; CD34+ derived human mast cell; PE; Phycoerythrin; PGD2; Prostaglandin D2; SCF; Stem cell factor; WDSM; Well-differentiate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular targets on mast cells and basophils for novel therapies

Keywords: Mast cell; basophil; mediator; receptor; signaling protein; survival protein; drug; therapy; BCL-2; B-cell lymphoma 2; BH; BCL-2 homology; Bs; Basophils; BTK; Bruton tyrosine kinase; CB; Endocannabinoid receptor; CRAC; Calcium release-activated calcium;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells

Keywords: Group 2 innate lymphoid cell; PGD2; chemoattractant receptor-homologous molecule expressed on TH2 cells; IL-25; IL-33; innate type 2 immunity; adaptive type 2 immunity; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; CSF-1; Mac

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Short communicationPossible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia

Keywords: Microglia; Phosphatidylserine liposomes; PGE2; PGD2; 15d-PGJ2; aiPLA2;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Yin-Yang regulation of prostaglandins and nitric oxide by PGD2 in human arthritis: Reversal by celecoxib

Keywords: PGD2; prostaglandin D2; PGE2; prostaglandin E2; DP2; prostanoid receptor DP2; L-PGDS; lipocalin-prostaglandin (PG) D synthase; H-PGDS; hematopoietic-prostaglandin (PG) D synthase; NO; nitric oxide; COX-1 or Ptgs1; cyclooxygenase 1; COX-2 or Ptgs2; cycloox

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery and characterization of NVP-QAV680, a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases

Keywords: BAL; bronchoalveolar lavage; BEMP; 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine; CCR-3; CC chemokine receptor 3; CRTh2; chemoattractant receptor homologous expressed on Th2 cells; DK-PGD2; 13,14-dihydro-15-keto-PGD2; ELSD;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation

Keywords: 15d-PGJ2; 15-deoxy-Δ12,14-PGJ2; AA; arachidonic acid; PPARγ; peroxisome proliferator-activated receptor γ; FXR; farnesoid X receptor; SPR; surface plasmon resonance; FQ; fluorescence quenching; HTRF; homo time-resolved fluorescence; BSEP; bile-salt exp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Isoquinoline derivatives as potent CRTH2 antagonists: Design, synthesis and SAR

Keywords: CRTH2 antagonist; Allergic diseases; Isoquinoline; PGD2;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluation of the prostaglandin F synthase activity of human and bovine aldo-keto reductases: AKR1A1s complement AKR1B1s as potent PGF synthases

Keywords: AA; arachidonic acid; AKR; aldo-keto reductases; BLOTTO; fat-free dry milk in PBS-T; COX; cyclooxygenase; DD3; dihydrodiol dehydrogenase 3; IL-1β; interleukine-1 beta; PBS-T; PBS with Tween 20; PGs; prostaglandins; PGD2; prostaglandin D2; PGE2; prostagla

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Rapid desensitization induces internalization of antigen-specific IgE on mouse mast cells

Keywords: Anaphylaxis; antigen; basophil; degranulation; desensitization; IgE; mast cell; rapid desensitization; receptor internalization; rush desensitization; BMCMC; Bone marrow-derived cultured mast cell; DNP; 2,4-Dinitrophenyl; FITC; Fluorescein isothiocyanat

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery of novel and potent CRTH2 antagonists

Keywords: CRTH2; DP2; PGD2; Asthma; Inflammation;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Optimization of phenylacetic acid derivatives for balanced CRTH2 and DP dual antagonists

Keywords: CRTH2; DP; PGD2; GPCR; Dual Antagonist; SAR; Asthma

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Optimization of phenylacetic acid derivatives for CRTH2 and DP selective antagonism

Keywords: CRTH2; DP; PGD2; GPCR; Antagonist; Asthma; Allergic diseases; Lead optimization; SAR;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Novel orexigenic pathway prostaglandin D2-NPY system - Involvement in orally active orexigenic δ opioid peptide

Keywords: PGD2; DP1 receptor; NPY; Y1 receptor; COX-2; L-PGDS; δ Opioid receptor; Rubiscolin-6; Leptomeninges; Food intake;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Isoquinoline derivatives as potent CRTH2 receptor antagonists: Synthesis and SAR

Keywords: CRTH2 antagonist; PGD2; Allergic diseases; Isoquinoline;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Hematopoietic prostaglandin D synthase (HPGDS): A high stability, Val187Ile isoenzyme common among African Americans and its relationship to risk for colorectal cancer

Keywords: Apc; adenomatous polyposis coli; CDNB; 1-chloro-2,4-dinitrobenzene; CI; confidence interval; dbSNP; the National Center for Biotechnology Information database for single nucleotide polymorphisms; HPGDS; hematopoietic prostaglandin D synthase; Min; a mouse

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Original Full Length ArticleProstaglandin D2 induces apoptosis of human osteoclasts by activating the CRTH2 receptor and the intrinsic apoptosis pathway

Keywords: PGD2; prostaglandin D2; PGE2; prostaglandin E2; DP; D-type prostanoid receptor; CRTH2; chemoattractant receptor homologous molecule expressed on T-helper type 2 cells; OC; osteoclast; RANKL; receptor activator for nuclear factor κB ligand; M-CSF; macroph

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Long-term CFTR inhibition modulates 15d-prostaglandin J2 in human pulmonary cells

Keywords: CFTR inhibitors; Cyclooxygenases; PGD2; 15d-PGJ2; Inflammatory cytokines

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Epigenetic deregulation of the COX pathway in cancer

Keywords: AKR1B1; aldo-keto reductase family 1 member B1; AOM; azoxymethane; COX; cycloxigenase; COX-1 (also known as PTGS1); cycloxigenase 1; COX-2 (also known as PTGS2); cycloxigenase 2; Coxibs; selective COX-2 inhibitors; CRTH2 (also known as DP2); chemoattrac

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Manipulation of vascular function by blood flukes?

Keywords: Schistosome; Parasite; Vasodilation; Vasoconstriction; Kinin; Histamine; Serotonin; Ecoisanoid; PGD2; PGE2; LTB4; LTC4; Nitric oxide; Adenosine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Azaindoles as potent CRTH2 receptor antagonists

Keywords: CRTH2; Chemoattractant receptor-homologous; PGD2; Prostanoid; Azaindole; Tetrahydropyridoindolizines

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Understanding DP receptor antagonism using a CoMSIA approach

Keywords: CoMSIA; QSAR; DP; DP1; Prostaglandin; PGD2; GPCR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Petasol butenoate complex (Ze 339) relieves allergic rhinitis-induced nasal obstruction more effectively than desloratadine

Keywords: Randomized controlled trial; allergic rhinitis; nasal obstruction; rhinomanometry; IL-8; leukotriene B4; histamine; Ze 339; petasol butenoate complex; Petasites hybridus; desloratadine; nasal allergen challenge; AOC; Area over the curve; AUC; Area under t

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists

Keywords: CRTH2 antagonists; Chemoattractant receptor-homologous molecule expressed on Th2 cells; PGD2; Scaffold hopping; Structure–activity relationships; Molecular modelling

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2

Keywords: CRTH2 antagonists; Chemoattractant receptor-homologous molecule expressed on Th2 cells; PGD2; Chemical libraries; Hit-to-lead; Structure–activity relationships; Molecular modeling

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Effects of palmitoylethanolamide on immunologically induced histamine, PGD2 and TNFα release from canine skin mast cells

Keywords: Canine mast cells; Endocannabinoids; PGD2; TNFα; Histamine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model

Keywords: CO-releasing molecule; CORM-3; HMGB1; K/BxN serum transfer arthritis; PGD2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

CD203c expression on human basophils is associated with asthma exacerbation

Keywords: Airway inflammation; asthma exacerbation; basophil activation; basophil surface marker; biomarker; CD203c; ENO; Exhaled nitric oxide; MFI; Mean fluorescence intensity; PEF; Peak expiratory flow; PGD2; Prostaglandin D2; 15R-MePGD2; 15(R)-methyl prostagland

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Expression of TREM-1 is inhibited by PGD2 and PGJ2 in macrophages

Keywords: Inflammation; TREM-1; LPS; Macrophage; Prostaglandin; PGD2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Recommandations pour le diagnostic et la prise en charge de la rhinite allergique (épidémiologie et physiopathologie exclues) - Texte long

Keywords: AINS; Anti-Inflammatoire Non Stéroïdien; ARIA; Allergic Rhinitis and its Impact on Asthma; DNS; Dysfonctionnement Naso-Sinusien; EFR; Épreuves Fonctionnelles Respiratoires; EMEA; European Medicines Evaluation Agency (Agence Européenne d'Evaluation d

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2010 سفارش ترجمه

Recommandations pour le diagnostic et la prise en charge de la rhinite allergique (épidémiologie et physiopathologie exclues) - Texte long

Keywords: AINS; Anti-Inflammatoire Non Stéroïdien; ARIA; Allergic Rhinitis and its Impact on Asthma; DNS; Dysfonctionnement Naso-Sinusien; EFR; Épreuves Fonctionnelles Respiratoires; EMEA; European Medicines Evaluation Agency (Agence Européenne d'Evaluation d

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2010 سفارش ترجمه

Prostaglandin D2 sustains the pyrogenic effect of prostaglandin E2

Keywords: PGD2; PGE2; Fever; Cerebrospinal fluid; Rat

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Central prostaglandin D2 exhibits anxiolytic-like activity via the DP1 receptor in mice

Keywords: PGD2; Anxiolytic-like activity; DP1 receptor; Adenosine A2A receptor; γ-Aminobutyric acid; GABAA receptor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Tetrahydroquinoline derivatives as CRTH2 antagonists

Keywords: CRTH2; PGD2; Antagonists; GPCR; Allergic diseases; Tetrahydroquinoline; SAR; Lead optimization;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Discovery and optimization of CRTH2 and DP dual antagonists

Keywords: CRTH2; DP; Antagonists; GPCR; Asthma; PGD2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia

Keywords: cerebral ischemia; middle cerebral artery occlusion; mouse; prostaglandins; PGD2; CBF; cerebral blood flow; COX; cyclooxygenase; H-PGDS; hematopoietic prostaglandin D synthase; L-PGDS; lipocalin-type prostaglandin D synthases; MABP; mean arterial blood pr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

GIF-0173 protects against cerebral infarction through DP1 receptor activation

Keywords: DP1 receptor; Glutamate; Intracellular calcium concentration; PGD2; GIF-0173

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Secreted phospholipases A2: A proinflammatory connection between macrophages and mast cells in the human lung

Keywords: AA; arachidonic acid; Akt; protein kinase B; BA; bronchial asthma; BAL; bronchoalveolar lavage; BBMCs; bone marrow-derived mast cells; COPD; chronic obstructive pulmonary disease; ERK1/2; extracellular-regulated kinase 1/2; HSPG; heparan sulfate proteogly

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis

Keywords: Prostaglandin D receptor gene promoter; asthma susceptibility; airway disease; montelukast; AE; Adverse experience; AR; Allergic rhinitis; CRTH2; Chemoattractant receptor-homologous molecule on T-helper type 2 cells, also known as DP2; DASS; Daytime Asthm

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2009 سفارش ترجمه

Met-Arg-Trp derived from Rubisco lowers blood pressure via prostaglandin D2-dependent vasorelaxation in spontaneously hypertensive rats

Keywords: Rubisco; ACE-inhibitory peptide; Vasorelaxation; PGD2; DP1 receptor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen

Keywords: PGD2; Prostanoid DP receptor; Allergic rhinitis; Nasal blockage; Nasal hyperresponsiveness; S-5751; Histamine; TXA2; U46619

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Inhibition of FcεRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement

Keywords: Siglec; mast cell; immunoreceptor tyrosine-based inhibitory motif; histamine; prostaglandin D2; IgE receptor; IRS; Inhibitory receptor superfamily; ITIM; Immunoreceptor tyrosine-based inhibitory motif; PGD2; Prostaglandin D2; SHP; src homology domain 2-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Anti-inflammatory effects and changes in prostaglandin patterns induced by 7β-hydroxy-epiandrosterone in rats with colitis

Keywords: Inflammation; Oxidative stress; COX-2; PGE2; PGD2; 15d-PGJ2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

7β-hydroxy-epiandrosterone modulation of 15-deoxy-Δ12,14-prostaglandin J2, prostaglandin D2 and prostaglandin E2 production from human mononuclear cells

Keywords: Steroids; 7β-Hydroxy-epiandrosterone; 15d-PGJ2; PGE2; PGD2; Human mononuclear cells; Inflammation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Comparison of short term in vitro cultured human mast cells from different progenitors - Peripheral blood-derived progenitors generate highly mature and functional mast cells

Keywords: PBS; phosphate buffered saline; BSA; bovine serum albumin; SCF; stem cell factor; FCS; foetal calf serum; APAAP; alkaline phosphatase anti-alkaline phosphatase; FACS; fluorescence-activated cell sorter; IL-4; interleukin-4; IgE; Myeloma IgE; CBMC; Cord bl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

An improved LC–MS/MS method for the quantification of prostaglandins E2 and D2 production in biological fluids

Keywords: Prostaglandins; PGD2; PGE2; Cell culture; A549 cells; RAW264.7 cells; LC–MS/MS

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه