Keywords: Carcinogenesis; Chemoprevention; Chemotherapy; Oxidative stress; Nrf2; Phytochemicals; AKT; protein kinase B; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ATF-2; activating transcriptional factor; BBN; N-butyl-N-(4-hydroxybutyl)n
مقالات ISI (ترجمه نشده)
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Keywords: HAA; heterocyclic aromatic amine; nd; non-detected; IQ; 2-amino-3-methylimidazo[4,5-f]quinoline; IQx; 2-amino-3-methylimidazo[4,5-f]quinoxaline; MeIQ; 2-amino-3,4-dimethylimidazo[4,5-f]quinoline; MeIQx; 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline; 4,8-D
Inhibitory effect of cellulose fibers on the formation of heterocyclic aromatic amines in grilled beef patties
Keywords: MeIQx (PubChem CID: 62275); 4,8-DiMeIQx (PubChem CID: 95896-78-9); PhIP (PubChem CID: 105650-23-5); Harman (PubChem CID: 486-84-0); Norharman (PubChem CID: 244-63-3); Microcrystalline cellulose (PubChem CID: 14055602); Carboxy methylcellulose (PubChem CID
Keywords: Array-CGH; array-based Comparative Genomic Hybridization; FISH; Fluorescence In Situ Hybridization; ISCN; International System for Human Cytogenomic Nomenclature; UCSC; University of California, Santa Cruz; TTK; TTK Protein Kinase; BCKDHB; Branched Chain
Keywords: Alternative sampling strategies; Adduct; DNA; Proteins; Biomarker; Dried blood spots; 4-ABP; 4-aminobiphenyl; AFB1; aflatoxin B1; B[a]P; benzo[a]pyrene; BChE; butyrylcholinesterase; DBS; dried blood spot; dG-C8; N-(deoxyguanosin-8-yl); DPS; dried plasma s
Keywords: Hyperpolarization; DNP; PHIP; MRSI; Pyruvate; Metabolic imaging; Molecular imaging; Cellular imaging;
Keywords: Heterocyclic amines; Serum albumin; Plasma; PhIP; LC-MS/MS; Protein adducts;
Keywords: 4,8-DiMeIQx; 2-amino-3,4,8-trimethyl-imidazo[4,5-f]quinoxaline; AcONH4; ammonium acetate; ACN; acetonitrile; AαC; 2-amino-9H-pyrido[2,3-b]indole; DMIP; 2-amino-1,6-dimethylimidazo[4,5-b]pyridine; FDP; freeze-dried product; Glu-P-1; 2-amino-6-methyldipyri
Keywords: Heterocyclic aromatic amines; MeIQx; PhIP; β-Carbolines; Processed meat; Bacon; Pan-frying; Creatin(in)e; Sensory quality; IQ (PubChem CID: 53462); IQx (PubChem CID: 108354-47-8); MeIQ (PubChem CID: 62274); MeIQx (PubChem CID: 62275); 4,8-DiMeIQx (PubChe
Keywords: 5(6)-CFDA; 5-(and-6)-carboxyfluorescein diacetate; AIG; anchorage-independent growth; ALDH; aldehyde dehydrogenase; ATCC; American Type Culture Collection; B[α]P; benzo[α]pyrene; BrdU; 5-bromo-2â²-deoxyuridine; CF; carboxyfluorescein; CM medium; comple
Keywords: CNTs; carbon nanotubes; c-MWCNTs; carboxylated multiwalled carbonanotubes; ILs; ionic liquids; BMIM·PF6; 1-butyl-3-methylimidazolium hexafluorophosphate; NC; nanocellulose; SDME; single-drop microextraction; DI; direct immersion; HS; head space; TEMPO; 2
Keywords: BaP; benzo(a)pyrene; BPDE; benzo(a)pyrene diol epoxide; CI; confidence interval; DiMeIQX; 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline; HCA; heterocyclic amine; HWE; Hardy Weinberg Equilibrium; LRT; likelihood ratio test; MeIQx; 2-amino-3,8-dimethylim
Keywords: Heterocyclic aromatic amine; PhIP; MeIQx; Hollow fibre membrane liquid-phase microextraction; Human plasma; UPLC-MS/MS;
Keywords: Spin hyperpolarization; Level anti-crossing; CIDNP; PHIP; SABRE;
Keywords: Parahydrogen; Hyperpolarization; Enhanced NMR; PHIP; PASADENA; J-spectrum; Inhomogeneous Fields; CPMG;
Keywords: AhR; aryl hydrocarbon receptor; AKT/PKB; protein kinase B; AOM; azoxymethane; AP; Acticoa power; AP-1; activator protein-1; ARE; antioxidant response element; CDK; cyclins-dpendent kinase; CLPr; cacao liquor proanthocyanidins; COX-2; cyclooxygenase-2; CYP
Reprint of: A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies
Keywords: 2D; two-dimensional; 3D; three-dimensional; AhR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; BCG; bromocresol green; CBMN; cytokinesis-blocked micronucleus; CBPI; cytokinesis-block proliferation index; CYP; cytochrome P450; DMSO; dimethyl sulfoxide;
A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies
Keywords: 2D; two-dimensional; 3D; three-dimensional; AhR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; BCG; bromocresol green; CBMN; cytokinesis-blocked micronucleus; CBPI; cytokinesis-block proliferation index; CYP; cytochrome P450; DMSO; dimethyl sulfoxide;
Alterations in the nigrostriatal dopamine system after acute systemic PhIP exposure
Keywords: PhIP; Heterocyclic amines; Dopaminergic toxicity; Parkinson's disease; Oxidative stress;
Recent technical and biological development in the analysis of biomarker N-deoxyguanosine-C8-4-aminobiphenyl
Keywords: 4-ABP; 4-aminobiphenyl; dG-C8-4-ABP; N-deoxyguanosine-C8-4-aminobiphenyl; LC-MS; liquid chromatography-mass spectrometry; PAHs; polycyclic aromatic hydrocarbons; NOCs; N-nitroso compounds; AAs; aromatic amines; CYP1A2; cytochrome P450 1A2; N-OH-ABP; N-hyd
Optimized phases for the acquisition of J-spectra in coupled spin systems for thermally and PHIP polarized molecules
Keywords: CPMG; CP; Echo trains; J-spectroscopy; NMR; Hyperpolarization; Parahydrogen; PHIP; Phase cycling; Pulse sequences; J-coupling; Spin dynamics;
Cigarette smoke condensate alters Saccharomyces cerevisiae efflux transporter mRNA and activity and increases caffeine toxicity
Keywords: ABC transporter; Pdr5; Snq2; Cigarette smoke; Caffeine; Saccharomyces cerevisiae; ABC; ATP-binding cassette; AαC; 2-amino-9H-pyrido[23-b]indole; 4- ABP; 4-aminobiphenyl; BaP; benzo(a)pyrene; BLAST; Basic local alignment search tool; BCRP; breast cancer r
Exposure to meat-derived carcinogens and bulky DNA adduct levels in normal-appearing colon mucosa
Keywords: DNA adducts; Polymorphism; Meat mutagenicity; PhIP; Colon;
Singlet order conversion and parahydrogen-induced hyperpolarization of 13C nuclei in near-equivalent spin systems
Keywords: PHIP; Singlet states; Hyperpolarization; Parahydrogen; SLIC;
Direct enhancement of nitrogen-15 targets at high-field by fast ADAPT-SABRE
Keywords: Hyperpolarization; PHIP; SABRE; ADAPT;
Alternating Delays Achieve Polarization Transfer (ADAPT) to heteronuclei in PHIP experiments
Keywords: PHIP; Singlet states; Hyperpolarization; Polarization transfer; ADAPT; SLIC; Parahydrogen; Long-lived states;
DNA adducts induced by food mutagen PhIP in a mouse model expressing human sulfotransferases 1A1 and 1A2
Keywords: CYP; cytochrome P450; 2â²-deoxyguanosine-PhIP; C8-(2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-N2-yl)-2â²-deoxyguanosine; h; human; hSULT mice; FVB mice expressing human sulfotransferases 1A1 and 1A2; NAT; N-acetyltransferase; PhIP; 2-amino-1-methyl
Magnetic resonance imaging of 1H long lived states derived from parahydrogen induced polarization in a clinical system
Keywords: Hyperpolarization; PHIP; Parahydrogen; Pulse sequence; Long lived state;
Perspectives for hyperpolarisation in compact NMR
Keywords: Dynamic nuclear polarisation (DNP); Parahydrogen-induced polarisation (PHIP); Signal amplification by reversible exchange (SABRE); Hyperpolarised gases; Spin-exchange optical pumping (SEOP); Low-field NMR; CIDNP; chemically induced dynamic nuclear polaris
Cooking methods and the formation of PhIP (2-Amino, 1-methyl, 6-phenylimidazo[4,5-b] pyridine) in the crust of the habitually consumed meat in Argentina
Keywords: Cooking method; Crust formation; Meat type; PhIP;
Development of an online-SPE-LC-MS method for the investigation of the intestinal absorption of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) and its bacterial metabolite PHIP-M1 in a Caco-2 Transwell system
Keywords: PHIP; 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; PHIP-M1; 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3â²,2â²:4,5]imidazo[1,2-a]pyrimidin-5-ium chloride; Papp; apparent permeability coefficient; HCA; heterocyclic aromatic amine; CE; colli
The antiepileptic drug lamotrigine is a substrate of mouse and human breast cancer resistance protein (ABCG2)
Keywords: Epilepsy; Pharmacoresistance; Transporter hypothesis; P-glycoprotein; AED; antiepileptic drug; AUC; area under curve; BBB; blood-brain barrier; BCRP/Bcrp; breast cancer resistance protein; CETA; concentration equilibrium transport assay; MDCK; Madin-Dar
Heterocyclic aromatic amines in grilled beef: The influence of free amino acids, nitrogenous bases, nucleosides, protein and glucose on HAAs content
Keywords: AIAs; aminoimidazoazaarenes; HAAs; heterocyclic aromatic amines; Trp-P 1; 3-amino-14-dimethyl-5H-pyrido[4,3-b]indole; Trp-P 2; 3-amino-1-methyl-5H-pyrido[43-b]indole; Glu-P-1; 2-amino-6-methyldipyrido[12-a:3,2-d]imidazole, Glu-P-22-aminodipyrido[1,2-a:3,2
Effects of beetroot (Beta vulgaris) preparations on the Maillard reaction products in milk and meat-protein model systems
Keywords: Beta vulgaris; Maillard reaction; CML; Furosine; Heterocyclic amines; PhIP;
Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets
Keywords: Phytochemicals; Cancer prevention; Reactive oxygen species; DNA damage; DNA adduct; Heterocyclic amines; AOPI; acridine orange/propidium iodide; BRCA-1; breast cancer 1 early onset; CAT; catalase; DCFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DEP
Spin polarization transfer mechanisms of SABRE: A magnetic field dependent study
Keywords: LAC; Level Anti-Crossing; MRI; Magnetic Resonance Imaging; NMR; Nuclear Magnetic Resonance; NSPD; Nuclear Spin Polarization Dispersion; o-H2; ortho-H2; p-H2; para-H2; PHIP; Para-Hydrogen Induced Polarization; Py; pyridine (aPy, axial Py; ePy; equatorial P
Parahydrogen discriminated PHIP at low magnetic fields
Keywords: Hyperpolization; Low field; NMR spectroscopy; J-spectra; CPMG; PHIP;
AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats
Keywords: PhIP; amino-1-methyl-6-phenylimidazo [4,5-b] pyridine; HCA; heterocyclic amine; ACF; aberrant crypt foci; GSEA; gene set enrichment analysis; Colon cancer; Rat; Susceptibility; Obesity; PhIP; AKT;
The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) elicits estrogenic-like microRNA responses in breast cancer cells
Keywords: PhIP; 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; miRNA; microRNA; ER; oestrogen receptor; ERα; oestrogen receptor alpha; ERβ; oestrogen receptor beta; HCA; heterocyclic amines; E2; 17-β-estradiol; DCCSS; dextran coated charcoal stripped serum; ER
The influence of Lactobacillus casei DN 114 001 on the activity of faecal enzymes and genotoxicity of faecal water in the presence of heterocyclic aromatic amines
Keywords: Probiotics; IQ; PhIP; β-glucuronidase; β-glucosidase; Genotoxicity
2-Alkenal-scavenging ability of m-diphenols
Keywords: 1D NMR; monodimensional NMR; 2D NMR; bidimensional NMR; MS; mass spectrometry; NMR; nuclear magnetic resonance spectroscopy; PhIP; 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; 2-Alkenals; Carbonyl-phenol adducts; Carbonyl-phenol reactions; Lipid o
Insights from analysis for harmful and potentially harmful constituents (HPHCs) in tobacco products
Keywords: 1,2,3,4,6,7,8-HpCDD; 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin; 1,2,3,4,6,7,8-HpCDF; 1,2,3,4,6,7,8-heptachlorodibenzo-p-furan; 1,2,3,4,7,8,9-HpCDF; 1,2,3,4,7,8,9-heptachlorodibenzo-p-furan; 1,2,3,4,7,8-HxCDD; 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin; 1,2,3,
Sensitivity enhancement in solution NMR: Emerging ideas and new frontiers
Keywords: NMR sensitivity; Hyperpolarization; Dissolution DNP; Overhauser DNP; Photo-CIDNP; PHIP; SEOP; Fast NMR;
Extracellular and intracellular anti-mutagenic effects of bile pigments in the Salmonella typhimurium reverse mutation assay
Keywords: AfB1; aflatoxin B1; BP(s); bile pigment(s); BR; unconjugated bilirubin; BRDT; bilirubin ditaurate; BV; biliverdin; PhIP; 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; S. typhimurium/Salmonella; Salmonella typhimurium; t-BOOH; tertiary butyl hydroperoxi
Comparative formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in creatinine/phenylalanine and creatinine/phenylalanine/4-oxo-2-nonenal reaction mixtures
Keywords: CRN; creatinine; HAAs; heterocyclic aromatic amines; MRM; multiple reaction monitoring; ON; 4-oxo-2-nonenal; Phe; phenylalanine; PhIP; 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; Heterocyclic amines; Lipid oxidation; Maillard reaction; Reactive carbo
Effect of amino acids on the formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in creatinine/phenylalanine and creatinine/phenylalanine/4-oxo-2-nonenal reaction mixtures
Keywords: AlaKA; pyruvic acid; CRN; creatinine; CysKA; mercaptopyruvic acid; GluKA; α-ketoglutaric acid; GlyKA; glyoxylic acid; HAAs; heterocyclic aromatic amines; IleKA; 3-methyl-2-oxovaleric acid; LeuKA; 4-methyl-2-oxovaleric acid; MetKA; α-keto-γ-methylthiobu
Aberrant activation of M phase proteins by cell proliferation-evoking carcinogens after 28-day administration in rats
Keywords: Carcinogen; M phase; Cell proliferation; Immunohistochemical analysis; SDM; sulfadimethoxine; PEITC; phenylethyl isothiocyanate; BHA; butylated hydroxyanisole; CC; catechol; PhIP; 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; CDCA; chenodeoxycholic aci
Chemical state of heterocyclic aromatic amines in grilled beef: Evaluation by in vitro digestion model and comparison of alkaline hydrolysis and organic solvent for extraction
Keywords: HAA; heterocyclic aromatic amines; Trp-P 1; 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole; Trp-P 2; 3-amino-1-methyl-5H-pyrido[4,3-b]indole; Harmane; 1-methyl-9H-pyrido[3,4-b]indole; Norharmane; 9H-pyrido[3,4-b]indole; AαC; 2-amino-9H-pyrido[2,3-b]indole;
Effects of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) on histopathology, oxidative stress, and expression of c-fos, c-jun and p16 in rat stomachs
Keywords: HCAs; heterocyclic amines; PhIP; 2-Amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine; SOD; superoxide dismutase; GPx; glutathione peroxidase; CAT; catalase; MDA; malondialdehyde; PCO; protein carbonyl; DPC; DNA-protein crosslinks; HE; hematoxylin-eosin; IH
Para-hydrogen perspectives in hyperpolarized NMR
Keywords: Para-hydrogen; PASADENA; ALTADENA; PHIP; SABRE; Metabolic imaging; Molecular imaging; Immobilized catalysts; Nanoparticles; Reaction monitoring; Remote detection; Low magnetic fields; Zero-field; Earth field; Trace detection; NMR spectroscopy; Gas phase i