دانلود مقالات ISI درباره Pi3K + ترجمه فارسی

A novel selenonucleoside suppresses tumor growth by targeting Skp2 degradation in paclitaxel-resistant prostate cancer

Keywords: CRPC; castration-resistant prostate cancer; PI3K; Phosphatidylinositol-4,5-bisphosphate 3 kinase; PTEN; Phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; BrdU; bromodeoxy-uridine; FITC; Fluorescein isothiocyanate; Skp2; S phase kinase-a

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

PI3K/AKT/mTOR activation and autophagy inhibition plays a key role in increased cholesterol during IL-17A mediated inflammatory response in psoriasis

Keywords: Psoriasis; IL-17A; Autophagy; Cholesterol; S100A7; LC3; mTOR (mammalian target of rapamycin); PI3K; AKT;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Ribosomal protein L10A and signaling pathway

Keywords: mRNA; messenger RNA; RpL10A; Ribosomal protein L10A; InR; insulin receptor; PCR; polymerase chain reaction; Akt; serine/threonine kinase; FOXO; forkhead box O; pre-mRNA; precursor mRNA; RSV; respiratory syncytial virus; Pwop phenotype; peas without pods p

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Bavachalcone from Cullen corylifolium induces apoptosis and autophagy in HepG2 cells

Keywords: C. corylifolium; Bavachalcone; Apoptosis; Cell cycle; Autophagy; CCE; Cullen corylifolium ethanol extract; HCC; hepatocellular carcinoma; NAFLD; Nonalcoholic fatty liver disease; Bax; bcl-2-associated X protein; Bcl-2; b-cell lymphoma 2; Bid; BH3 interact

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression

Keywords: PPARγ; Peroxisome proliferator-activated receptor γ; ECM; extracellular matrix; TGF-β; transforming growth factor-β; PI3K; phosphoinositide 3-kinase; F-actin; filamentous-actin; TNF-α; tumor necrosis factor-α; IL; interleukin; FCS; fetal calf serum;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

The role of insulin signalling in the endocrine stress response in Drosophila melanogaster: A mini-review

Keywords: JH; juvenile hormone; JHE; JH-esterase; DA; dopamine; ALP; alkaline phosphatase; TH; tyrosine hydroxylase; OA; octopamine; TDC; tyrosine decarboxylase; 20E; 20-hydroxyecdysone; E20MO; ecdysone 20-monooxygenase; CA; corpus allatum; IIS; insulin/insulin-lik

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Unravelling the role of fatty acid metabolism in cancer through the FOXO3-FOXM1 axis

Keywords: Fatty acids; Cancer; Lipid metabolism; FOXO3; FOXM1; AKT/PI3K pathway; AKT; protein kinase B; AMPK; adenosine monophosphate-activated-activated protein kinase; APN; adiponectin; CoA; coenzyme A; CPT1; carnitine palmitoyltransferase 1; DHA; docosahexaenoic

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

The feedback loop of “EMMPRIN/NF-κB” worsens atherosclerotic plaque via suppressing autophagy in macrophage

Keywords: Atherosclerosis; Extracellular matrix metalloproteinase inducer; Macrophage autophagy; Nuclear factor kappa B; Vulnerable plaque; AMPK; Adenosine Monophosphate Activated Protein Kinase; ApoE −/−;  Apolipoprotein E-deficient; AS; atherosclerosis; CQ;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

HOXB4 knockdown enhances the cytotoxic effect of paclitaxel and cisplatin by downregulating ABC transporters in ovarian cancer cells

Keywords: ABCB1; ATP Binding Cassette Subfamily B Member 1; ABCC1; ATP Binding Cassette Subfamily C Member 1; ABCG2; ATP Binding Cassette Subfamily G Member 2; HOXB13; Homeobox B13; HOXB4; Homeobox B4; LDH; lactate dehydrogenase; PI3K; phosphatidylinositol 3-kinase

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Protective effect of Sesbania grandiflora on acetic acid induced ulcerative colitis in mice by inhibition of TNF-α and IL-6

Keywords: CD; Chron's Disease; DAI; Disease Activity Index; FFA; Free Fatty acid; GSH; Glutathione-S-transferase; IBD; Inflammatory Bowel Disease; IL-6; Interleukin −6; JNK; C-JUN -Terminal kinase; LPO; Lipid peroxidation; MDA; Malondialdehyde; MPO; Myeloperoxi

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Involvement of mTOR, JNK and PI3K in the negative effect of ethanol and metformin on the human first-trimester extravillous trophoblast HTR-8/SVneo cell line

Keywords: mTOR; JNK; PI3K; Ethanol; Metformin; Trophoblasts;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

The interaction of IGF-1/IGF-1R and hydrogen sulfide on the proliferation of mouse primary vascular smooth muscle cells

Keywords: BrdU; bromodeoxyuridine; CBS; cystathionine-beta-synthase; CRISPR; clustered regularly interspaced short palindromic repeats; CSE; cystathionine-gamma-lyase; DMEM; dulbecco's modified eagle's medium; ERK; extracellular regulated protein kinase; FBS; f

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Loss of c-KIT expression in breast cancer correlates with malignant transformation of breast epithelium and is mediated by KIT gene promoter DNA hypermethylation

Keywords: Breast Cancer; c-KIT; Epigenetics; DNA methylation; Immunohistochemistry; ADH; Atypical ductal hyperplasia; BCA; Bicinchoninic acid; CML; Chronic myelogenous leukemia; CK5/6; Cytokeratin 5/6; CK903; Cytokeratin 903; DCIS; Ductal Carcinoma in situ; ER; Est

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Endocrine and physiological regulation of neutral fat storage in Drosophila

Keywords: Lipid metabolism; Drosophila; Obesity; Insulin; TOR; Ecdysone; AGPAT; acylglycerol-3-phosphate acyltransferase; AKH; adipokinetic hormone; BMM; Brummer; CC; corpora cardiac; DAG; diacylglycerol; Dilp; Drosophila insulin-like peptide; DGAT; diacylglycerol

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Cross-talk between EGFR and IL-6 drives oncogenic signaling and offers therapeutic opportunities in cancer

Keywords: EGFR; epidermal growth factor receptor; IL-6; interleukin 6; ADC; antibody-drug conjugate; HGF; hepatocyte growth factor; c-met/MET; tyrosine-protein kinase Met; CTLA-4; cytotoxic T-lymphocyte-associated protein 4; VEGF; vascular endothelial growth factor

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Estradiol up-regulates L-type Ca2+ channels via membrane-bound estrogen receptor/phosphoinositide-3-kinase/Akt/cAMP response element-binding protein signaling pathway

Keywords: Akt; Estrogen; Genomic regulation; L-type Ca2+ channel; Pi3K; p-CREB;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery

Keywords: Single chain antibody(scFv); OX40; Antibody drug conjugate; Drug delivery; Internalization; Thermal stability of antibody; OX40L; OX40 lignad; scFv; single-chain variable fragment; scFvC; scFv carrying a C-terminal cysteine residue; IκB; nuclear factor o

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Emerging roles of microRNAs in the metabolic control of immune cells

Keywords: Non-coding RNAs; Immunometabolism; T cells; Macrophages; Metabolic reprogramming; ATP; adenosine triphosphate; TCA; tricarboxylic acid cycle; PPP; pentose phosphate pathway; FAO; fatty acid oxidation; PEP; phosphoenolpyruvate; α-KG; alpha-ketoglutarate;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

FOXOs in cancer immunity: Knowns and unknowns

Keywords: 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation and function of runt-related transcription factors (RUNX1 and RUNX2) in goat granulosa cells

Keywords: RUNX1; runt-related transcription factor 1; RUNX2; runt-related transcription factor 2; hCG; human chorionic gonadotropin; LH; Luteinizing Hormone; FSK; forskolin; PMA; phorbol 12-myristate 13-acetate; PI3K; phosphatidylinositol 3 kinase; PKA; protein kin

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes

Keywords: Ac-DEVD-AMC; N-acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin; AKT; protein kinase B; AMP; ampicillin; ATB; antibiotic; ATF6; activating transcription factor 6; BC; bile canaliculi; BSEP; bile salt export pump; CDF; 5(6)-carboxy-2,7-dichlorofluorescein;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer

Keywords: 7-AAD; 7-amino-actinomycin D; ABC; ATP-binding cassette; AEC; 3-amino-9-ethyl carbazole; ATD; acute toxicity determination; Atg5; autophagy protein 5; ATP; adenosine-5′-triphosphate; BCL-2; B-cell lymphoma 2; Bip/GRP78; binding immunoglobulin protein/78

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Class I PI3K inhibitor ZSTK474 attenuates experimental autoimmune neuritis by decreasing the frequency of Th1/Th17 cells and reducing the production of proinflammatory cytokines

Keywords: AUC; area under the curve; CMAP; compound muscle action potential; DAPI; 4′,6-diamidino-2- phenylindole; dpi; days post-inoculation; EAN; experimental autoimmune neuritis; ELISA; enzyme-linked immunosorbent assay; EMG; electromyography; GAPDH; glycerald

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition

Keywords: Akt; protein kinase B; Bax; Bcl-2 associated X; Bcl-2; B-cell lymphoma 2; DAPI; 4′,6-diamidino-2-phenylindole; DDP; cisplatin; EMT; epithelial-to-mesenchymal transition; FBS; fetal bovine serum; GAPDH; glyceraldeyde 3-phosphate dehydrogenase; HRP; horse

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Control of progression towards liver fibrosis and hepatocellular carcinoma by SOCS3 polymorphisms in chronic HCV-infected patients

Keywords: HCV; Hepatitis C Virus; CHC; Chronic Hepatitis C; HCC; Hepatocellular Carcinoma; IR; Insulin Resistance; T2D; Type 2 Diabetes; MENA; Middle-Esat and North Africa; IRS-1/2; Insulin receptor substrate-1/2; PI3K; phosphatidylinositol 3-kinase; SOCS-3; Suppre

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Oocyte-G1 promotes male germ cell apoptosis through activation of Caspase-3

Keywords: Kif; Kinesin superfamily; TUNEL; Transferase-mediated deoxyuridine triphosphate-biotin nick end labeling; Pro-caspase-3; Prototype of caspase-3; PCNA; Proliferating Cell Nuclear Antigen; STAT3; Signal transducer and activator of transcription 3; TGF-β; T

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Systemic L-buthionine-S-R-sulfoximine administration modulates glutathione homeostasis via NGF/TrkA and mTOR signaling in the cerebellum

Keywords: GSH; Cysteine transport; NGF; mTOR; Redox; Cerebellum; 4F2hc; 4F2 cell surface antigen; BBB; blood-brain barrier; BSO; L-buthionine-S-R-sulfoximine; CNS; central nervous system; DAPI; 4′,6-diamidino-2-phenylindole DTPA; diethylenetriamine penta-acetic a

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological evaluation of novel 4-aminoquinazolines as dual target inhibitors of EGFR-PI3Kα

Keywords: EGFR; PI3K; Dual target; 4-aminoquinazolines; Antiproliferative effects; Anticancer agents;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Sulfiredoxin-1 enhances cardiac progenitor cell survival against oxidative stress via the upregulation of the ERK/NRF2 signal pathway

Keywords: SRXN1; sulfiredoxin-1; ALDH; aldehyde dehydrogenase; CoPP; Cobalt protoporphyrin; ΔΨm; mitochondrial membrane potential; BCL2; B-cell CLL/lymphoma 2; BCL-XL; BCL2-like 1; FACS; fluorescence-activated cell sorter; ALDHbr-hCPCs; aldehyde dehydrogenase bri

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

GS-9620 inhibits enterovirus 71 replication mainly through the NF-κB and PI3K-AKT signaling pathways

Keywords: Enterovirus 71; Hand; Foot and mouth disease; GS-9620; NF-κB and PI3K-AKT signaling pathways; EV71; Human enterovirus 71; TLR7; Toll-like receptor 7; NF-κB; nuclear factor kappa B; PI3K; phosphoinositide 3-kinase; hpi; hours post infection;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

The cardenolide ouabain suppresses coronaviral replication via augmenting a Na+/K+-ATPase-dependent PI3K_PDK1 axis signaling

Keywords: Cardenolide; Coronavirus; Na+/K+-ATPase; Ouabain; PI3K; PDK1;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

BCAP promotes osteoclast differentiation through regulation of the p38-dependent CREB signaling pathway

Keywords: BCAP; B-cell adaptor for PI3K; PI3K; phosphatidylinositol 3-Kinase; BMM; bone marrow-derived monocyte/macrophage lineage cell; NFATc1; nuclear factor of activated T-cells c1; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

STAT3 Mediates Nilotinib Response in KIT-Altered Melanoma: A Phase II Multicenter Trial of the French Skin Cancer Network

Keywords: AE; adverse event; AKT; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; CI; confidence interval; CR; complete response; GIST; gastrointestinal stromal tumors; JAK; Janus kinase; MAPK; mitogen-activated protein kinase; OS; overall survival;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Protective effects of diketopiperazines from Moslae Herba against influenza A virus-induced pulmonary inflammation via inhibition of viral replication and platelets aggregation

Keywords: Cyclo(Tyr-Leu) (PubChem CID: 15550385); Cyclo(Phe-Phe) (PubChem CID: 76116); Cyclo(Phe-Tyr) (PubChem CID: 11438306); Cyclo(Ala-Ile) (PubChem CID: 45359405); Cyclo(Ala-Leu) (PubChem CID: 3634567); Diketopiperazines; Platelets aggregation; Anticoagulant act

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms

Keywords: ABC; ATP-binding cassette; ABCA1; ATP-binding membrane cassette transporter A1; ABCG1; ATP binding cassette transporter G1; ABCA7; ATP-binding cassette transporters A7; Abs; Antibodies; ACs; Apoptotic cells; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ri

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

F2-isoprostanes affect macrophage migration and CSF-1 signalling

Keywords: Akt; Protein Kinase B; BMM; Bone Marrow derived Macrophages; BSA; Bovine Serum Albumin; Chol-IsoP; Cholesterol-Isoprostane; CSF-1; Colony Stimulating Factor-1; CSF-1R; Colony Stimulating Factor-1 Receptor; DAPI 4′; 6-Diamidino-2-phenylindole; DMSO; Dime

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

The effects of wild bitter gourd fruit extracts on ICAM-1 expression in pulmonary epithelial cells of C57BL/6J mice and microRNA-221/222 knockout mice: Involvement of the miR-221/-222/PI3K/AKT/NF-κB pathway

Keywords: WBGE; Inflammation; ICAM-1; miR-221/-222; PI3K/AKT; NF-κB; AKT; protein kinase B; C; Control; CH; charantin; COPD; chronic obstructive pulmonary disease; DMEM; Dulbecco's modified Eagle's medium; ERK; extracellular-signal-regulated kinase; ICAM; intercel

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells

Keywords: HCC; hepatocellular carcinoma; 5-FU; 5-fluorouracil; MEL; melittin; P-gp; P-glycoprotein; AMPs; antimicrobial peptides; LDH; lactate dehydrogenase; SEM; scanning electron microscope; BMSCs; bone mesenchymal stem cells; IGF-I; insulin­like growth factor I

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

PI3K pathway in prostate cancer: All resistant roads lead to PI3K

Keywords: CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Non-tumor adjacent tissue of advanced stage from CRC shows activated antioxidant response

Keywords: CRC; colorectal cancer; SIRT3; sirtuin 3; MSI; microsatellite instability; NRAS; neuroblastoma RAS viral oncogene homolog; BRAF; v-raf murine sarcoma viral oncogene homolog B; KRAS; Kirsten rat sarcoma viral oncogene homolog; PI3K; phosphatidylinositide 3

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Insulin-signaling Pathway Regulates the Degradation of Amyloid β-protein via Astrocytes

Keywords: ACE; angiotensin-converting enzyme; AD; Alzheimer's disease; Aß; amyloid ß-protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ECE; endothelin-converting enzyme; EDTA; ethylenediaminetetraacetic acid; EGCG; epigallocatechi

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Concomitance of EGFR mutations and ALK rearrangement in patients with Lung Cancer

Keywords: ALK; Anaplastic lymphoma kinase; EGFR; Epithelial growth factor receptor; EML4; Echinoderm Microtubule Associated Protein Like 4; K-Ras; Kirsten rat sarcoma viral; MAPK; Mitogen-activated protein kinases; NSCLCs; Non-small cell lung cancers; PI3K; Phospha

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

PI3K regulates intraepithelial cell positioning through Rho GTP-ases in the developing neural tube

Keywords: neural tube; PI3K; neuroepithelium; apical-basal polarity; cell invasion;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway

Keywords: ACC; acetyl-CoA carboxylase; Ac-Lys; acetylated lysine; AMPK; AMP-activated protein kinase; BMMCs; bone marrow-derived mast cells; HSA; human serum albumin; IKK; IκB kinase; IL-6; interleukin-6; JNK; c-Jun N-terminal kinase; LAT; linker for activation of

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Phthalimide conjugations for the degradation of oncogenic PI3K

Keywords: Cancer; Drug design; Degrade; Antitumor activity; PI3K;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

A change in structural integrity of c-Kit mutant D816V causes constitutive signaling

Keywords: JAK; Janus kinase; JM region; juxtamembrane region; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; MD; molecular dynamics; MIHC; Myb-immortalized haemopoietic cells; WT; wild-type c-Kit; WTp; wild-type phosphorylated c-Kit; MT_D816V

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of bisphenol A on metabolism and evidences of a mode of action mediated through endocrine disruption

Keywords: Bisphenol A; BPA; Endocrine disruption; Obesity; Type 2 diabetes; Insulin; BAT; brown adipose tissue; BMI; body mass index; bw; body weight; DES; diethylstilbestrol; DM; Diabete mellitus; ED; endocrine disruptor; eGFR; estimated glomerular filtration; ERR

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

ER stress and cancer: The FOXO forkhead transcription factor link

Keywords: Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Raffinose from Costus speciosus attenuates lipid synthesis through modulation of PPARs/SREBP1c and improves insulin sensitivity through PI3K/AKT

Keywords: Anti-diabetes; Anti-adipogenesis; Lipid metabolism; Insulin signaling; ACC; acetyl-CoA carboxylase; ACO; Acyl CoA Oxidase; Comp C; Compound C; CSEW; Costus speciosus ethanolic water extract; DMEM; Dulbecco's Modified Eagle Medium; FAS; fatty acid synthase

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo

Keywords: Acute myeloid leukemia; PI3K; mTOR; ERK; Bcl-2;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه