Correlation between platelet and brain PLA2 activity
Keywords: PLA2; Platelets; Brain tissue; Hippocampus; Neuropsychiatric disorders; Epilepsy; Radioenzymatic assays;
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Antibacterial properties of recombinant human non-pancreatic secretory phospholipase A2
Keywords: PLA2; phospholipase A2; sPLA2; secretory phospholipase A2; hnpsPLA2; human non-pancreatic secretory phospholipase A2; Human non-pancreatic secretory phospholipase A2; Bactericidal activity; Gram-positive bacteria; Gram-negative bacteria; pH;
Class specific peptide inhibitors for secretory phospholipases A2
Keywords: AMP; antimicrobial peptides; bv; bee venom; C28-O-PHPM; 1-octosanyl-2-(pyren-1-yl)hexanoyl-sn-glycero-3-phospho-monomethyl ester; cPLA2; cytosolic PLA2; CSSP; continuum secondary structure predictor; EM; electron microscopy; FFA; free fatty acid; Hsp70; h
Translational studies on regulation of brain docosahexaenoic acid (DHA) metabolism in vivo
Keywords: DHA; Docosahexaenoic acid; AA; Arachidonic acid; LA; Linoleic acid; α-LNA; α-linolenic acid; DPA; Docosapentaenoic acid; EDP; Epoxy-docosapentaenoic acid; EPA; Eicosapentaenoic acid; PLA2; Phospholipase A2; cPLA2; Cytosolic PLA2; sPLA2; Secretory PLA2;
PAFAH Ib phospholipase A2 subunits have distinct roles in maintaining Golgi structure and function
Keywords: PLA2; PAFAH Ib; Golgi complex; Secretory trafficking;
Characterization of the aqueous extract of the root of Aristolochia indica: Evaluation of its traditional use as an antidote for snake bites
Keywords: AFM; atomic force microscopy; ALP; alkaline phosphatase; APTES; 3-aminopropyltriethoxysilane; ATA; aurintricarboxylic acid; BSA; bovine serum albumin; CHAPS; 3[(3-Cholamidopropyl)dimethylammonio]-propanesulfonic acid; CHCA; α-cyano-4-hydroxycinnamic acid
Determination of phospholipase activity of PAF acetylhydrolase
Keywords: C6NBD PC; 1-palmitoyl-2-(7-nitrobenzoxadiazolyl)aminocaproyl phosphatidylcholine; DEACZ; 7-diethylaminocoumarin-3-carbonyl azide; DNGP; 1-decanoyl-2-(4-nitrophenylglutaryl) phosphatidylcholine; PAF; platelet-activating factor; PAF-AH; platelet-activating
Differential modification of the phospholipid profile by transient ischemia in rat hippocampal CA1 and CA3 regions
Keywords: AA; arachidonic acid; CM; ceramide; DHA; docosahexaenoic acid; PC; phosphatidylcholine; PE; phosphatidylethanolamine; PE-pl; plasmalogen; PI; phosphatidylinositol; PLA2; phospholipase A2; PS; phosphatidylserine; SM; sphingomyelin; Polyunsaturated fatty ac
Effect of allergy and inflammation on eicosanoid gene expression in CFTR deficiency
Keywords: LTs; leukotrienes; LTB4; leukotriene B4; cysLTs; cysteinyl leukotrienes; PLA2; phospholipase A2; sPLA2; secretory PLA2; cPLA2; group IV PLA2; HPETEs; hydroperoxyeicosatetraenoic acids; HETEs; hydroxyeicosatetraenoic acids; CF; cystic fibrosis; Af; Aspergi
Emerging roles of secreted phospholipase A2 enzymes: An update
Keywords: Phospholipase A2; Lipid; Arachidonic acid; Atherosclerosis; Inflammation; DHA; docosahexaenoic acid; DPA; docosapentaenoic acid; DRG; dorsal root ganglion; GI; gastrointestinal; LDL; low-density lipoprotein; LXR; liver X receptor; LPS; lipopolysaccharide;
Calpains participate in nerve terminal degeneration induced by spider and snake presynaptic neurotoxins
Keywords: Presynaptic neurotoxins; Calpain; Ca2+ toxicity; Neurodegeneration; Ach; acetylcholine; [Ca2+]; calcium concentration; FA; fatty acid; α-Ltx; alpha-latrotoxin; LysoPC; lysophosphatidylcholine; NF; neurofilament; NMJ; neuromuscular junction; Ntx; notexin;
The interaction of a polymeric persimmon proanthocyanidin fraction with Chinese cobra PLA2 and BSA
Keywords: Persimmon tannin; PLA2; Structure modification; Covalent modification; Protein affinity; BSA;
Suppression of severe lesions, myonecrosis and hemorrhage, caused by Protobothrops flavoviridis venom with its serum proteins
Keywords: Protobothrops flavoviridis venom; Phospholipase A2; Myonecrosis; Serum protein; Phospholipase A2 inhibitor; Antivenom; HRP; horse radish peroxidase; HSF; Habu serum factor; Pf; Protobothrops flavoviridis; PLA2; phospholipase A2; PLI; PLA2 inhibitor;
Peroxisome proliferator-activated receptor (PPAR)β/δ, a possible nexus of PPARα- and PPARγ-dependent molecular pathways in neurodegenerative diseases: Review and novel hypotheses
Keywords: AP-1; activator protein 1; BDNF; brain-derived neurotrophic factor; CNTF; ciliary neurotrophic factor; COX-2; cyclooxygenase-2; EAE; experimental autoimmune encephalomyelitis; FGF-2; fibroblast growth factor-2; IP3; inositol 1,4,5-trisphosphate; IP3R; IP3
Specific roles for Group V secretory PLA2 in retinal iron-induced oxidative stress. Implications for age-related macular degeneration
Keywords: retina; iron; PLA2; oxidative stress; AMD; acyltransferases; AA; arachidonic acid; AMD; age-related macular degeneration; AT; acyltransferases; ATK; arachidonoyl trifluoromethyl ketone; Bcl-2; B-cell lymphoma 2; BEL; bromoenol lactone; BSA; bovine serum a
Interaction of characteristic structural elements of persimmon tannin with Chinese cobra PLA2
Keywords: Persimmon tannin; PLA2; Inhibition; Fluorescence spectra; Molecular docking;
Identification of novel phospholipase A2 group IX members in metazoans
Keywords: GIX phospholipase A2; GXIV phospholipase A2; Conserved domain; Pfam09056; PLA2; phospholipase A2; sPLA2; secreted phospholipase A2; GIX PLA2; group IX phospholipase A2; GXII PLA2; group XII phospholipase A2; GXIV PLA2; group XIV phospholipase A2; cd; cons
Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation
Keywords: 15d-PGJ2; 15-deoxy-Î12,14-PGJ2; AA; arachidonic acid; PPARγ; peroxisome proliferator-activated receptor γ; FXR; farnesoid X receptor; SPR; surface plasmon resonance; FQ; fluorescence quenching; HTRF; homo time-resolved fluorescence; BSEP; bile-salt exp
Triacontyl p-coumarate: An inhibitor of snake venom metalloproteinases
Keywords: Bg; Bombacopsis glabra; BleucMP; PI metalloproteinase; BnSP-6; Lys49 PLA2; Bp; Bothropoides pauloensis; Jar; Jararhagin; MS; mass spectrometry; Neu; PI metalloproteinase (Neuwiedase); NMR; nuclear magnetic resonance; PLA2; phospholipase A2; PCT; triaconty
Mycology, cultivation, traditional uses, phytochemistry and pharmacology of Wolfiporia cocos (Schwein.) Ryvarden et Gilb.: A review
Keywords: AIF; apoptosis-inducing factor; 5-Fu; 5-fluorouracil; IC50; fifty percent inhibitory concentration; NO; nitric oxide; PLA2; phospholipase A2; PU; Polyurethane; S-180; sarcoma 180; TPA; 12-O-tetradecanoylphorbol-13-acetate; WSP; water-soluble pachyman; Wol
Plasma membrane Pdia3 and VDR interact to elicit rapid responses to 1α,25(OH)2D3
Keywords: 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; VDR; vitamin D receptor; Pdia3; protein disulfide isomerase family A, member 3; PLA2; phospholipase A2; PLAA; PLA2 activating protein; PGE2; prostaglandin E2; PI3K; phosphatidylinositol 3-kinases; Alpl; alkaline
Nox4 and diabetic nephropathy: With a friend like this, who needs enemies?
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; AA; arachidonic acid; AGE; advanced glycation end-product; Akt/PKB; Akt/protein kinase B; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; AOPP; advanced oxidation protein product; AT1; angiotensin II t
Surfactant phospholipid metabolism
Keywords: ABC; ATP-binding cassette transporter; ARDS; acute respiratory distress syndrome; CCT-CTP; phosphocholine cytidylyltransferase; CDP-choline; cytidine diphosphocholine; CDP-DAG; CDP-diacylglycerol; CDS-CDP; diacylglycerol synthase; CK; choline kinase; CL;
Differences in the toxicity of six Gambierdiscus (Dinophyceae) species measured using an in vitro human erythrocyte lysis assay
Keywords: Cell lysis; Ciguatoxins; Ciguatera fish poisoning; Hemolytic assay; Maitotoxin; Regional differences in toxicity; Calpains; calcium-dependent, non-lysosomal cysteine proteases; Hemolytic assay; the abbreviated name for erythrocyte lysis assay; LC-MS; Li
DL-/PO-phosphatidylcholine may shed light on the treatment of Alzheimer dementia
Keywords: Phosphatidylcholine; Donepezil hydrochloride; Alzheimer dementia; MMSE; DL-PC; 1,2-dilinoleoyl-sn-glycero-3-phosphocholine; PO-PC; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; MMSE; Mini-Mental State Examination; ACh; acetylcholine; AChEIs; acetylcho
Interaction of a β-lactam calixarene derivative with a model eukaryotic membrane affects the activity of PLA2
Keywords: DLPC model membranes; Langmuir films; Calixarene derivative; Drug–membrane interaction; PLA2; Enzymatic catalysis
Effect of repetitive daily ethanol intoxication on adult rat brain: Significant changes in phospholipase A2 enzyme levels in association with increased PARP-1 indicate neuroinflammatory pathway activation
Keywords: Alcohol; Neuroinflammation; PLA2; AQP4; Neurodegeneration; Arachidonic acid; PARP-1; ParthanatosAA, arachidonic acid; AQP4, aquaporin-4; DHA, docosahexaenoic acid; EC, entorhinal cortex; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HC, hippocampus; PA
Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase
Keywords: 5-Hydroxytryptamine; Optimization; PLA2; LTA4H; Dual function inhibitorJPQGMWDCOJLDDP-UHFFFAOYSA-N; BANCSZURRKITHC-UHFFFAOYSA-N; SPDOMOCWKCKHME-UHFFFAOYSA-N; GLIMPFCMXKKPHS-UHFFFAOYSA-N; WKPDXBXNJWWWGQ-UHFFFAOYSA-N; UGENTLRMJJZPQJ-UHFFFAOYSA-N; WLZYNMBYGU
A radioenzymatic assay to identify three groups of phospholipase A2 in platelets
Keywords: Phospholipids; PLA2; Platelets; Neuropsychiatric disorders; Radioenzymatic assays
Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases
Keywords: LPA; lysophosphatidic acid; ATX; autotaxin; 2-AcMAGE; 2-acetyl monoalkylglycerol ether, 1-O-hexadecyl-sn-2-acetyl glycerol; MAGE; monoalkylglycerol ether, 1-O-hexadecyl-sn-glycerol; MAG; monoacylglycerol; AGK/MuLK; acylglycerol kinase/multiple lipid subst
Venom evolution through gene duplications
Keywords: PLA2; phospholipase A2; Ig; immunoglobulin; aa; amino acids; bp; base pairs; EST; expressed sequence tag; Gene duplication; Venom; Adaptation; Toxin; Genomics;
Toll recognition signal activates oenocytoid cell lysis via a crosstalk between plasmatocyte-spreading peptide and eicosanoids in response to a fungal infection
Keywords: ACB; anticoagulant buffer; dsRNA; double-stranded RNA; GBP; growth-blocking peptide; OCL; oenocytoid cell lysis; PG; prostaglandin; PLA2; phospholipase A2; PO; phenoloxidase; PSP; plasmatocyte-spreading peptide; RNAi; RNA interference; RT-qPCR; real time
Cloning and characterization of Trimeresurus gracilis venom phospholipases A2: Comparison with Ovophis okinavensis venom and the systematic implications
Keywords: Trimeresurus gracilis venom phospholipase; cDNA cloning and sequencing; Pitviper systematic; Platelet aggregation inhibitor; dPPC; L-dipalmitoyl phosphatidylcholine; PLA2; phospholipase A2; HPLC; high performance liquid chromatography; PRP; platelet rich
Characterization of a highly polymeric proanthocyanidin fraction from persimmon pulp with strong Chinese cobra PLA2 inhibition effects
Keywords: Persimmon proanthocyanidin; MALDI TOF/MS; Thiolysis HPLC; Structure; PLA2; Inhibition
The multi-faceted roles of prostaglandin E2 in cancer-infiltrating mononuclear phagocyte biology
Keywords: 13-PGR; Î13-15-ketoprostaglandin reductase; 15-PGDH; 15-prostaglandin dehydrogenase; APC; adenomatous polyposis coli; BM; bone marrow; cAMP; cyclic adenosine monophosphate; cDC; conventional DC; COX; cyclooxygenase; CTL; cytotoxic lymphocyte; DC; dendrit
Dietary methylmercury and vegetable oil affects brain lipid composition in Atlantic salmon (Salmo salar L.)
Keywords: ARA; arachidonic acid; CE; cholesteryl ester; CHOL; cholesterol; cPLA2; cytosolic phospholipase A2; DAG; diacylglycerol; DHA; docosahexaenoic acid; DPA; docosapentaenioc acid; EPA; eicosapentaenoic acid; FABP; fatty acid binding protein; FATP; fatty acid
Purification and inflammatory edema induced by two PLA2 (Anch TX-I and Anch TX-II) from sea anemone Anthothoe chilensis (Actiniaria: Sagartiidae)
Keywords: Anthothoe chilensis; PLA2; Edematogenic; HPLC-RP; Rat paw edema;
Mechanism of the sex difference in neuronal ischemic cell death
Keywords: DMEM; Dulbecco's-Modified Eagle Medium; DMSO; Dimethylsulfoxide; EETs; epoxyeicosatrienoic acids; LC-MS/MS; liquid chromatography-tandem mass spectrometry; MCAO; middle cerebral artery occlusion; PLA2; phospholipase A2; OGD; oxygen-glucose deprivation;
Differential regulation of collagen secretion by kinin receptors in cardiac fibroblast and myofibroblast
Keywords: B1R; bradykinin 1 receptor; B2R; bradykinin 2 receptor; BK; bradykinin; CF; cardiac fibroblasts; CMF; TGF-beta-treated CF; COX; cyclooxygenase; DAKD; des-Arg10-KD; eNOS; endothelial nitric oxide synthase; iNOS; inducible nitric oxide synthase, 1400W induc
Secreted phospholipase A2 group IIA is a neurotoxin released by stimulated human glial cells
Keywords: AD; Alzheimer's disease; BPPA; 5-(4-benzyloxyphenyl)-4S-(7-phenylheptanoylamino) pentanoic acid; ConA; concanavalin A; DMDA; 7,7-dimethyl-5,8-eicosadienoic acid; DMEM-F12; Dulbecco's modified Eagle medium nutrient mixture F-12 Ham; DMSO; dimethyl sulfoxid
Phospholipase A2 activating protein is required for 1α,25-dihydroxyvitamin D3 dependent rapid activation of protein kinase C via Pdia3
Keywords: PLAA; phospholipase A2 activating protein; Pdia3; protein-disulfide isomerase-associated 3; PKC; protein kinase C; PLA2; phospholipase A2; PGE2; prostaglandin E2; AA; arachidonic acid; PLC; phospholipase C; BS3; bis(sulfosuccinimidyl) substrate; 1α,25(OH
Crotoxin and phospholipases A2 from Crotalus durissus terrificus showed antiviral activity against dengue and yellow fever viruses
Keywords: Antiviral; Dengue virus; Yellow fever virus; Crotoxin; PLA2
CyrA, a matricellular protein that modulates cell motility in Dictyostelium discoideum
Keywords: CaM; Calmodulin; CaMBP; CaM-binding protein; CaMBD; CaM-binding domain; CaMBOT; CaM-binding overlay technique; EGFL; Epidermal growth factor-like; EGFR; EGF receptor; ECM; Extracellular matrix; Ten14; 14th EGFL repeat of tenascin C; MMP2; Matrix metallopr
'PUFA-GPR40-CREB signaling' hypothesis for the adult primate neurogenesis
Keywords: AC; adenylyl cyclase; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ARA; arachidonic acid; BDNF; brain-derived neurotrophic factor; BrdU; bromodeoxyuridine; [Ca2+]i; intracellular Ca2+ concentration; CaMK; calmodulin-dependent kinase; cAMP;
Identification of Brassica napus lysophosphatidylcholine acyltransferase genes through yeast functional screening
Keywords: PC; phosphatidylcholine; LPC; lysophosphatidylcholine; LPCAT; acyl-CoA:lysophosphatidylcholine acyltransferase; PLA2; phospholipase A2; lyso-PAF; lyso-platelet-activating factor; DAG; diacylglycerol; TAG; triacylglycerol; MBOAT; membrane-bound O-acyltrans
EGF-like peptide-enhanced cell movement in Dictyostelium is mediated by protein kinases and the activity of several cytoskeletal proteins
Keywords: EGF; epidermal growth factor; EGFL; EGF-like; EGFL1; 1st EGFL repeat of CyrA; EGFR; EGF receptor; EGFRL; EGFR-like protein; Ten14; 14th EGFL repeat of tenascin C; ECM; extracellular matrix; CaM; calmodulin; CaMBP; CaM binding protein; MHC; myosin II heavy
The genus Commiphora: A review of its traditional uses, phytochemistry and pharmacology
Keywords: ABTS; 2,2â²-azino-di-[3-ethylbenzthiazoline sulphonate]; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; COX; cyclooxygenase; CNS; central nervous system; DPPH; 2,2-diphenyl-1-picrylhydrazyl; FXR; farnesoid X re
Epigenetic deregulation of the COX pathway in cancer
Keywords: AKR1B1; aldo-keto reductase family 1 member B1; AOM; azoxymethane; COX; cycloxigenase; COX-1 (also known as PTGS1); cycloxigenase 1; COX-2 (also known as PTGS2); cycloxigenase 2; Coxibs; selective COX-2 inhibitors; CRTH2 (also known as DP2); chemoattrac
Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis
Keywords: 7α-OH; 7α-hydroxycholesterol; 7-K; 7-ketocholesterol; 9-ONC; 9-oxononanoyl cholesterol; 15d-PGJ2; 15-deoxy-Î12,14-prostaglandin J2; α-EPOX; 5α,6α-epoxycholesterol; AP-1; activator protein-1; ARE; antioxidant-responsive element; ATF; activating trans
Using mice to unveil the genetics of cancer resistance
Keywords: AC; adenocarcinoma; AOM; azoxymethane; APC; antigen-presenting cells; BH; BCL2 homology; CCl4; carbon tetrachloride; cM; centimorgan; COX; cyclo-oxygenase; CTLA-4; cytotoxic T-lymphocyte antigen 4; DC; dendritic cells; DEN; diethylnitrosamine; DMBA; 7,12-