Keywords: همخوانی Pleckstrin; CSR; complete spatial randomness; EM; electron microscopy; FAPP1; four-phosphate-adaptor protein 1; FRAP; fluorescence recovery after photobleaching; GFP; green fluorescent protein; GST; glutathione S-transferase; IMP; intramembrane particle; INPP5E; inos
مقالات ISI همخوانی Pleckstrin (ترجمه نشده)
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Keywords: همخوانی Pleckstrin; Actin dynamics; Rho GTPases; dendritic spines; postsynapse; Abi-1; Abelson interacting protein 1; Abp1; actin binding protein 1; ACTN4; α-actinin-4; ADF; actin-depolymerizing factor; ADHD; attention deficit/hyperactivity disorder; ADNP; activity-dependen
Keywords: همخوانی Pleckstrin; AC; adenylate cyclase; Actn4; α-Actinin-4; ARF6; ADP-ribosylation factor 6; ATD; amino terminal domain; CAIN; calcineurin inhibitor protein; CaM; calmodulin; CaMKII; Ca2+/calmodulin-dependent protein kinase II; Cbln1; cerebellin 1 precursor; CC; coiled-c
Keywords: همخوانی Pleckstrin; CISK; cytokine-independent survival kinase; EEA1; early endosomal autoantigen 1; EHD; Eps15 homology domain; Hrs; hepatocyte growth factor-regulated tyrosine kinase substrate; PH; pleckstrin homology; PI; phosphoinositide; PLC; phospholipase C; QF-FRL; qu
Keywords: همخوانی Pleckstrin; ABPP; activity-based protein profiling; ALPS; amphipathic lipid packing sensor; CERT; ceramide transport protein; CG; coarse-grained; DESRES; D.E. Shaw research; DMS; DESRES molecular structure; EM; electron microscopy; EPR; electron paramagnetic resonanc
Keywords: همخوانی Pleckstrin; AbA; Aureobasidin A; ABC; ATP-binding cassette; AMPK; AMP-activated protein kinase; ATG; Autophagy-related; ATP; Adenosine triphosphate; C1P; Ceramide-1-phosphate; CERS; Ceramide synthase; CK2; Casein kinase II; CLS; Chronological lifespan; CMA; Chaperone
Keywords: همخوانی Pleckstrin; CAPRI; Ca2+-promoted RAS inactivator; CRMP-2; collapsin response mediator protein-2; CSRD; cysteine/serine-rich domain; CTD; C-terminal domain; ERK; extracellular signal-regulated kinase; FTI; farnesyltransferase inhibitor; FAK1; focal adhesion kinase 1;
Keywords: همخوانی Pleckstrin; CERT; ceramide transfer protein; CETP; cholesteryl ester transfer protein; ER; endoplasmic reticulum; FABP; fatty acid-binding protein; FFAT; diphenylalanine in an acidic tract; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GLs;
Keywords: همخوانی Pleckstrin; PI3K; phosphoinositide 3-kinase; PH; pleckstrin homology; 4IP; inositol-(1,3,4,5)-tetrakisphosphate; PI3P; 3-phosphorylated phosphatidylinositol; PTC; papillary thyroid carcinoma; SQAG; sulfoquinovosylacylglycerols; Sulfoquinovose; Phosphatidyl inositol a
Keywords: همخوانی Pleckstrin; CERT; ceramide transfer protein; ER; endoplasmic reticulum; FFAT; two phenylalanines in an acidic tract; LE; late endosome; LTP; lipid transfer protein; MCS; membrane contact site; OSBP; oxysterol-binding protein; ORP; OSBP-related protein; ORD; OSBP-rela
Keywords: همخوانی Pleckstrin; AMPK; AMP-activated protein kinase; ATG; autophagy-related; CL; cardiolipin; EM; electron microscopy; EMC; ER membrane protein complex; ER; endoplasmic reticulum; ERMES; ER-mitochondria encounter structure; FFAT; two phenylalanines in an acid tract; HOPS;
Keywords: همخوانی Pleckstrin; TM; transmembrane; MP; membrane protein; GpA; glycophorin A; PIP; phosphatidylinositol phosphate; PI; phosphatidylinositide; RTK; receptor tyrosine kinase; MHC; major histocompatibility complex; PG; phosphatidyl glycerol; PS; phosphatidyl serine; PLC; pho
Keywords: همخوانی Pleckstrin; CK; creatine kinase; DMD; Duchenne muscular dystrophy; EHD; Eps15 homology domain; FC; founder cell; FCM; fusion competent myoblasts; LGMD; limb girdle muscular dystrophy; PH; pleckstrin homology; PIP2; phosphatidylinositol 4,5-bisphosphate; PS; phosphati
Keywords: همخوانی Pleckstrin; AP-AB; anti-phospholipid antibody(ies); APS; anti-phospholipid syndrome; BMP/LBPA; bis(monoacylglycero)phosphate/lysobisphosphatidic acid; CAD; cationic amphiphilic drug(s); Chol; cholesterol; CL; cardiolipin; ECV/MVB; endosomal carrier vesicle(s)/multive
Keywords: همخوانی Pleckstrin; Akt; protein kinase B; DHA; docosahexaenoic acid; ERK; extracellular signal-regulated protein kinase; NAPE; N-acylphosphatidylethanolamine; PC; phosphatidylcholine; PDK1; phosphoinositide-dependent kinase-1; PE; phosphatidylethanolamine; PEMT; phosphatidy
Keywords: همخوانی Pleckstrin; AP-1; activator protein-1; BLNK; B cell linker protein; BTK; Bruton's tyrosine kinase; CCT; choline cytidylyltransferase; CDP-choline; cytidine diphosphocholine; CEPT1; choline/ethanolamine phosphotransferase 1; Cer; ceramide; CK; choline kinase; CPT1; ch
Keywords: همخوانی Pleckstrin; ABCA12; ATP-binding cassette transporter A12; α-GalCer; α-galactosylceramide; AMPK; AMP-activated protein kinase; BMP; bis-monoacylglycero-phosphate; CBE; conduritol B epoxide; CerS; ceramide synthase; CERT; ceramide transport protein; ChlGlc; cholester
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention
Keywords: همخوانی Pleckstrin; ER; estrogen receptor; mTORC2; mammalian target of rapamycin complex 2; PDK1; phosphoinositide-dependent kinase-1; PH; pleckstrin homology; PI3K; phosphatidylinositol 3-kinase; PX; Phox; SGK; serum and glucocorticoid inducible protein kinase; SGK; AKT; PI
AKT1 distinctively suppresses MyD88-depenedent and TRIF-dependent Toll-like receptor signaling in a kinase activity-independent manner
Keywords: همخوانی Pleckstrin; TLR; Toll-like receptor; TRIF; Toll/IL-1R domain-containing adaptor inducing IFN-β; LPS; lipopolysaccharide; KD; kinase-dead; IRAK; IL-1R-associated kinase; ISG; interferon stimulated gene; PIP3; phosphatidylinositol (3,4,5) trisphosphate; PH; pleckstrin
G protein-coupled receptor kinases: Past, present and future
Keywords: همخوانی Pleckstrin; αN-helix; N-terminal α-helical domain; α2AAR; α2A-adrenergic receptor; AST; active site tether; βAR; β-adrenergic receptor; β2AR; β2-adrenergic receptor; βARK; β-adrenergic receptor kinase; CLBD; C-terminal lipid binding domain; EM; electron mic
The beneficial effects of Zn on Akt-mediated insulin and cell survival signaling pathways in diabetes
Keywords: همخوانی Pleckstrin; Akt2-KO; Akt2 gene deletion; CHO; Chinese hamster ovary; DM; diabetes mellitus; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; GLUT4; glucose transporter type-4; GS; glycogen synthase; GSK-3; glycogen synt
Novel nuclear translocation of inositol polyphosphate 4-phosphatase is associated with cell cycle, proliferation and survival
Keywords: همخوانی Pleckstrin; INPP4A; inositol polyphosphate 4 phosphatase type I enzyme; LMB; leptomycin B; PtdIns(P); phosphatidyl inositol phosphate; Ins(1,4,5)P3; Inositol 1,4,5 tris-phosphate; PDK-1; phosphoinositide-dependent kinase-1; mTORC2; mammalian target of rapamycin compl
Oxysterol-binding protein-related protein (ORP) 6 localizes to the ER and ER-plasma membrane contact sites and is involved in the turnover of PI4P in cerebellar granule neurons
Keywords: همخوانی Pleckstrin; DIV; days in vitro; ER; endoplasmic reticulum; ERGIC; ER-Golgi intermediate compartment; E-Syt2; extended synaptotagmin2; FFAT; two phenylalanines in an acidic tract; GalT; 1,4-galactosyltransferase; ORD; OSBP-related ligand binding domain; ORP; oxyster
Direct regulation of p190RhoGEF by activated Rho and Rac GTPases
Keywords: همخوانی Pleckstrin; RhoGEF; Rho guanine nucleotide exchange factors; RhoGAP; GTPase-activating proteins; DH; Dbl homology; PH; pleckstrin homology; PRG; PDZRhoGEF; TEV; Tobacco Etch Virus; His6; hexahistidine peptide; GST; glutathione S-transferase; ITC; isothermal titration
The role of small molecule platelet-derived growth factor receptor (PDGFR) inhibitors in the treatment of neoplastic disorders
Keywords: همخوانی Pleckstrin; Axitinib: (PubMED CID: 6450551); Dasatinib: (PubMED CID: 3062316); Imatinib: (PubMED CID: 5291); Lenvatinib: (PubMED CID: 9823820); Nilotinib: (PubMed CID: 644241); Nintedanib: (PubMed CID: 9809715); Ponatinib: (PubMed CID: 24826799); Sorafenib: (PubMed C
A pleckstrin homology-like domain is critical for F-actin binding and cofilin-phosphatase activity of Slingshot-1
Keywords: همخوانی Pleckstrin; Slingshot; Cofilin; Pleckstrin homology (PH) domain; Actin binding; Phosphatase; Btk; Bruton's tyrosine kinase; CD; circular dichroism; CFP; cyan fluorescent protein; Itk; interleukin-2-inducible T-cell tyrosine kinase; LHK motif; Leu-His-Lys motif; OSBP;
Activation of Aplysia ARF6 induces neurite outgrowth and is sequestered by the overexpression of the PH domain of Aplysia Sec7 proteins
Keywords: همخوانی Pleckstrin; 5-HT; 5-hydroxyltryptamine; PH; pleckstrin homology; ARF; ADP-ribosylation factor; GTPase; guanosine triphosphatase; GEF; guanine nucleotide exchange factor; PI(3,4,5)P3; phosphatidylinositol (3,4,5)-trisphosphate; KD; kinase-dead; ApARF6; Aplysia ARF6; A
Sialidase NEU3 defines invasive potential of human glioblastoma cells by regulating calpain-mediated proteolysis of focal adhesion proteins
Keywords: همخوانی Pleckstrin; FAK; Focal adhesion kinase; FA; Focal adhesion; ECM; Extracellular matrix; Suc-LLVY-AMC; Succinyl-L-leucyl-L-leucyl-L-valyl-L-tyrosine 4-methylcoumaryl-7-amide; PIP2; Phosphatidylinositol 4, 5-bisphosphate; TLC; Thin-layer chromatography; Sulfo-NHS-biotin
The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells
Keywords: همخوانی Pleckstrin; AEBSF; 4-(2-aminoethyl)-benzolsulfonylfluorid; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; Epo; erythropoietin; EpoR; erythropoietin receptor; Erk; extracellular signal regulated kinase; FCS; fetal calf serum; Gab1; G
The C1 domain of Vav3, a novel potential therapeutic target
Keywords: همخوانی Pleckstrin; DAG; diacylglycerol; PKC; protein kinase C; GEF; guanine nucleotide exchange factor; PMA; phorbol 12-myristate 13-acetate; PDBu; phorbol 12,13-dibutyrate; CH domain; calponin homology domain; AD; acidic domain; DH; Dbl homology; PH; Pleckstrin homology; S
PPIP5K1 interacts with the exocyst complex through a C-terminal intrinsically disordered domain and regulates cell motility
Keywords: همخوانی Pleckstrin; Arp2/3; actin-related protein 2/3 complex; CBD; calmodulin binding domain; DIPP; diphosphoryl inositol polyphosphate phosphohydrolase; EXOC1-8; exocyst complex component 1-8; GST; Glutathione-S-transferase; HA; hemagglutinin; InsPP; inositol pyrophosp
Kindlin-1 Regulates Keratinocyte Electrotaxis
Keywords: همخوانی Pleckstrin; EF; electric field; KS; Kindler syndrome; KS_MT; kindlin-1-mCherryW612A point mutation; KS_WT; Kindler syndrome cells infected with wild-type kindlin-1-mCherry; NHK; normal human keratinocyte; PH; pleckstrin homology; PI(3)K; phosphoinositide 3-kinase
The Interaction Mode of the Acidic Region of the Cell Cycle Transcription Factor DP1 with TFIIH
Keywords: همخوانی Pleckstrin; DBD; DNA-binding domain; GAL4 DBD; DBD of GAL4; HSQC; heteronuclear single quantum coherence; LZ; leucine zipper; MB; marked box; TAD; transactivation domain; pRB; retinoblastoma protein; PH; pleckstrin homology; WT; wild-type; NOE; nuclear Overhauser eff
Threonine 34 phosphorylation by phosphoinositide-dependent protein kinase 1 facilitates dissociation of Akt from the plasma membrane
Keywords: همخوانی Pleckstrin; Akt; protein kinase B; IGF; insulin-like growth factor; KD; kinase domain; MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2; MS; mass spectrometry; PDK; phosphoinositide-dependent protein kinase; PH; pleckstrin homology; PIK3; phospha
Yeast-based methods to assess PTEN phosphoinositide phosphatase activity in vivo
Keywords: همخوانی Pleckstrin; CWI; cell wall integrity; Gal; galactose; MAPK; mitogen-activated protein kinase; mTOR; mammalian target of rapamycin; PDK1; phosphoinositide-dependent kinase; PH; pleckstrin homology; PI3K; phosphoinositide 3-kinase; PtdIns(4,5)P2; phosphatidylinositol (
APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription
Keywords: همخوانی Pleckstrin; AP-1; activating protein 1; APPL; adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif; CKI; casein kinase I; Dvl; Dishevelled; GST; glutathione S-transferase; JNK; c-Jun N-terminal kinase; LRP; lo
The Ras/Rap GTPase activating protein RASA3: From gene structure to in vivo functions
Keywords: همخوانی Pleckstrin; Ras; Rap; GTPase activating protein; RASA3; Megakaryocyte; Platelet; Cancer; Leukemia; AML; acute myeloid leukemia; Btk; Bruton tyrosine kinase; [Ca2+]i; intracellular calcium concentration; EBV; Epstein-Barr virus; GAP; GTPase activating protein; GEF; gu
Lipid agonism: The PIP2 paradigm of ligand-gated ion channels
Keywords: همخوانی Pleckstrin; AA; arachidonic acid; ASIC; acid-sensing ion channel; ATP; adenosine triphosphate; BK; big conductance potassium channel; Cav; voltage-dependent calcium channel or VDCC; Ci-VSP; Ciona intestinalis voltage-sensitive phosphatase; CoA; coenzyme A; CTD; cytop
PI3K/Akt signaling in osteosarcoma
Keywords: همخوانی Pleckstrin; OS; osteosarcoma; PI3K; phosphatidylinositol 3-kinase; PTEN; phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; RTKs; receptor tyrosine kinases; PDGFR; platelet-derived growth factor receptor; IGF1R; insulin-like growth factor 1 receptor
OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity
Keywords: همخوانی Pleckstrin; BiFC; bimolecular fluorescence complementation; ER; endoplasmic reticulum; FFAT; two phenylalanines in an acidic tract; GST; glutathione S-transferase; hyper-P; hyperphosphorylated; hypo-P; hypophosphorylated; LTP; lipid binding/transfer protein; MCS; mem
Arabidopsis dynamin-related proteins, DRP2A and DRP2B, function coordinately in post-Golgi trafficking
Keywords: همخوانی Pleckstrin; BiFC; bi-molecular fluorescent complementation; CLSM; confocal laser scanning microscopy; CoIP-MS; co-immunoprecipitation mass spectrometry; DRP; dynamin-related protein; GED; GTPase-effector domain; Lat B; latrunculin B; ORY; oryzalin; PH; pleckstrin hom
Spatial and temporal expression of RA70/Scap2 in the developing neural tube
Keywords: همخوانی Pleckstrin; Retinoic acid; SKAP55; Scap; Neural tube; Integrin; BAC; bacterial artificial chromosome; CC; coiled-coil; EC; embryonic carcinoma; ES; embryonic stem; IRES; internal ribosome entry sites; Neo; neomycin resistance; PH; pleckstrin homology; RA; retinoic ac
The activity of the anti-apoptotic fragment generated by the caspase-3/p120 RasGAP stress-sensing module displays strict Akt isoform specificity
Keywords: همخوانی Pleckstrin; PH; pleckstrin homology; PI3K; phosphatidylinositide 3-kinase; PIP3; phosphatidylinositol 3,4,5-trisphosphate; mTORC2; mammalian target of rapamycin complex 2; PDK1; phosphoinositide-dependent kinase 1; FasL; Fas ligand; GFP; green fluorescent protein; KO
PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway
Keywords: همخوانی Pleckstrin; DH; dbl homology; DHR; dock homology region; DMEM; Dulbecco's modified Eagle's medium; Eph; ephrin receptor; FBS; fetal bovine serum; GAP; GTPase activating protein; G-protein; guanosine triphosphate-binding protein; GPCR; heterotrimeric G-protein-coupled
Vav1 increases Bcl-2 expression by selective activation of Rac2-Akt in leukemia T cells
Keywords: همخوانی Pleckstrin; GEF; guanine nucleotide exchange factor; T-CVID; T cell type common variable immunodeficiency; B-CLL; B-cell chronic lymphocytic leukemia; shRNA; short-hairpin RNA; SDS-PAGE; SDS-polyacrylamide gel electrophoresis; GST; Glutathione S-transferase; PAK1; p2
The guanine nucleotide exchange factor Tiam1: A Janus-faced molecule in cellular signaling
Keywords: همخوانی Pleckstrin; DH; Dbl homology; JIP/IB2; c-Jun N-terminal kinase-interacting protein/islet-brain 2; GAP; GTPase-activating protein; GDP; guanosine diphosphate; GDI; guanine dissociation inhibitor; GEF; guanine nucleotide-exchange factor; GTP; guanosine triphosphate; PH
Activation of PI3K/Akt signaling in rostral ventrolateral medulla impairs brain stem cardiovascular regulation that underpins circulatory depression during mevinphos intoxication
Keywords: همخوانی Pleckstrin; aCSF; artificial cerebrospinal fluid; Akt; serine/threonine protein kinase; EMSA; electrophoretic mobility shift assay; HR; heart rate; LF; low-frequency; 3-MA; 3-methyladenine; NF-κB; nuclear factor-κB; NO; nitric oxide; NOS; nitric oxide synthase; NRS
Insight into the structural mechanism for PKBα allosteric inhibition by molecular dynamics simulations and free energy calculations
Keywords: همخوانی Pleckstrin; PKB/Akt; protein kinase B; MD; molecular dynamics; PI3K; phosphatidylinostiol-3-kinase; PDK1; 3â²-phosphoinositide-dependent kinase-1; PTEN; phosphatase and tensin homolog; MM/PBSA; molecular mechanics/Poisson Boltzmann surface area; MM/GBSA; molecular m
The links between AKT and two intracellular proteolytic cascades: Ubiquitination and autophagy
Keywords: همخوانی Pleckstrin; BRCA1; breast cancer susceptibility gene 1; BRCT; Brca1 C-terminal; CHIP; chaperone-associated ubiquitin ligase; CYLD; cylindromatosis; DAPK; death-associated protein kinase; DUB; deubiquitinating enzyme); EGF; epidermal growth factor; FADD; fas-associate
Plant phosphoinositide-dependent phospholipases C: Variations around a canonical theme
Keywords: همخوانی Pleckstrin; Phospholipase C; Lipid signalling; Phosphoinositides; Inositol-phosphate; Phosphatidic acid; ABA; abscisic acid; DAG; diacylglycerol; DGK; DAG-kinase; IP3; inositol triphosphate; IP5; inositol pentakisphosphate; IP6; inositol hexakisphosphate; PA; phospha