Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention

150The serum and glucocorticoid inducible protein kinases (SGKs) are associated with the PI3K signalling pathway, and share similar structure, substrate specificity and function with AKT. SGKs not only regulate cell proliferation and survival, but also play important roles in cancer development via an AKT-independent signalling pathway.