Keywords: منطقه قطبی; FFA1; Hypoglycemia; Non-biphenyl scaffold; Polar surface area; Type 2 diabetes;
مقالات ISI منطقه قطبی (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: منطقه قطبی; Immobilized artificial membrane; Time-of-flight mass spectrometry; Blood-brain barrier; Quantitative structure-activity relationship; Liquid chromatography; High-throughput; AA; ammonium acetate; APC; Amemiya predictive criterion; BBB; blood-brain barrier
Keywords: منطقه قطبی; Polar drugs; Diffusion; Hydrophobic thickness; Area modulus; Polar surface area; ASA; acetylsalicylic acid; Calcein; 3,3-bis[N,N-bis(carboxymethyl)-aminomethyl]fluorescein; CMC; critical micellization concentration; CSâ1; compressibility modulus; CW STE
Keywords: منطقه قطبی; d-Aspartic acid; Stereoinversion; Replica exchange molecular dynamics simulation; Polar surface area; Solvent accessibility; Structural flexibility;
Keywords: منطقه قطبی; permeability; ophthalmic drug delivery; QSPR; absorption; principal component analysis; partial least square; HBD; hydrogen bond donor; logD7.4; the logarithm of the octanol-water partition coefficient at pH 7.4; MW; molecular weight; Papp,CJ; apparent co
Keywords: منطقه قطبی; PCP; physicochemical properties; Ro5; Lipinski rule of five; PCA; principal component analysis; AlogP; partition coefficient; GABA; gamma-aminobutyric acid; PSA; polar surface area; MR; molecular refractivity; QED; quantitative estimate of drug-likeness;
Keywords: منطقه قطبی; Transdermal; Hydroxyl pressure sensitive adhesive; Drug release; Physicochemical parameter; log P; Polar surface area; Polarizability;
Keywords: منطقه قطبی; transdermal; ion pair; zaltoprofen; polar surface area; confocal laser scanning microscopy; molecular modeling; FTIR; NMR; permeability;
Keywords: منطقه قطبی; 3D; three-dimensional; c log P; the calculated log octanol/water partition coefficient; DNA; deoxyribonucleic acid; ATP; adenosine triphosphate; HPT1; intestinal peptide-associated transporter 1; PEPT1; peptide transporter 1; OCT; organic cation transpo
Keywords: منطقه قطبی; ABC; ATP-binding cassette; GSH; glutathione; IC50; half-maximal inhibitory concentration; IFN-γ; interferon-gamma; iNOS; inducible NO synthase; IRF-1; interferon regulatory factor-1; ITC; isothiocyanate; Kobs; Pseudo-first order reaction rate constant; L
Keywords: منطقه قطبی; 1,3-Dipolar-cycloaddition; Fatty acid; Mode of action; MR; molar refractivity; MW; molecular weight; MV; molecular volume; PASS; predicted activity spectrum of substances; PSA; polar surface area; SAR; structure-activity relationship; MIC; minimal inhib
Learning how to use IAM chromatography for predicting permeability
Keywords: منطقه قطبی; BR Analysis; Block Relevance Analysis; IAM; Immobilized Artificial Membranes; LFER; Linear Free Energy Relationships; MDCK-LE; Low-Efflux Madin-Darby canine kidney cell line; PAMPA; Parallel Artificial Membrane Permeability Assay; PPL; phospholipids; PSA;
Andrographolide-loaded nanoparticles for brain delivery: Formulation, characterisation and in vitro permeability using hCMEC/D3 cell line
Keywords: منطقه قطبی; AG; andrographolide; ATM; adsorptive-mediated transcytosis; BBB; blood-brain barrier; BSA; bovine serum albumin; CNS; central nervous system; DLS; Dynamic Light Scattering; DMSO; dimethyl sulfoxide; ECA; ethylcyanoacrylate; EE; encapsulation efficiency; E
Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro blood-brain barrier and intestinal drug permeability studies
Keywords: منطقه قطبی; 4-HPAA; 4-hydroxyphenyl acetic acid; ACN; acetonitrile; BSA; bovine serum albumin; Cal; calibrator; CCl; cell layer capacitance; CNS; central nervous system; CV%; coefficient of variation; CPT-cAMP; 8-(4-chlorophenylthio)-adenosine-3â²,5â²-cyclic monoph
Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation
Keywords: منطقه قطبی; Primaquine; Urea; Bis-urea; Antiproliferative activity; Antioxidative activity; Antimicrobial activity; AAPH; 2,2'-azobis(2-amidinopropane) hydrochloride; BtcCl; 1-benzotriazole carboxylic acid chloride; BtH; 1H-benzo[d][1,2,3]triazole; CEM; acute lymphob
Solid lipid nanoparticles of clotrimazole silver complex: An efficient nano antibacterial against Staphylococcus aureus and MRSA
Keywords: منطقه قطبی; MRSA; methicillin-resistant Staphylococcus aureus; MSSA; methicillin-susceptible Staphylococcus aureus; CTM; clotrimazole; RT; room temperature; CTM- Ag; clotrimazole-silver complex; MTT; 3-(4,5- Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; MHA;
Coronaridine congeners inhibit human α3β4 nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites
Keywords: منطقه قطبی; AChR; nicotinic acetylcholine receptor; NCA; noncompetitive antagonist; RT; room temperature; Ki; inhibition constant; Kd; dissociation constant; IC50; ligand concentration that produces 50% inhibition of binding (or of agonist activation); nH; Hill coeff
Aryl methylcarbamates: Potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 strain An. gambiae
Keywords: منطقه قطبی; aa; amino acid; AChE; acetylcholinesterase; AgAChE; Anopheles gambiae AChE; ATCh; acetylthiocholine; hAChE; human AChE; hmg; homogenate; IRS; indoor residual spraying; ITN; insecticide-treated net; PSA; polar surface area; Acetylcholinesterase; Anopheles
Defining the key pharmacophore elements of PF-04620110: Discovery of a potent, orally-active, neutral DGAT-1 inhibitor
Keywords: منطقه قطبی; DGAT-1; Diabetes; Obesity; Passive permeability; Carboxylic acid bioisotere; Polar surface area;
Discovery of 3-aryloxy-lactam analogs as potent androgen receptor full antagonists for treating castration resistant prostate cancer
Keywords: منطقه قطبی; Androgen receptor; AR antagonist; Prostate cancer; Ligand efficiency; Polar surface area; PSA; Castration resistant prostate cancer; CRPC; LBD; NHR;
Inhibitory effect of 10 natural phenolic compounds on Fusarium verticillioides. A structure-property-activity relationship study
Keywords: منطقه قطبی; Fusarium verticillioides; Natural phenolic compounds; QSAR; Lipophilicity; Molar refractivity; Saturated area; FW; formule weight; MR; molar refractivity; MV; molar volumen; ST; surface tension; P; polarizability; log P; logarithm of the octanol/water pa
Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern
Keywords: منطقه قطبی; Cannabinoid CB1 receptor; Site of metabolism prediction; Metasite; Rimonabant; Subtype selectivity; Polar surface area; Lipophilicity; P-Glycoprotein
Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies
Keywords: منطقه قطبی; Binding efficiency index; Ligand efficiency; Cannabinoid CB2 receptor; Inverse agonist; Polar surface area; Lipophilicity; Subtype selectivity; Ligand-lipophilicity efficiency; Lipophilic efficiency
Bile acid toxicity structure-activity relationships: Correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A)
Keywords: منطقه قطبی; GCA; glcyocholic acid; GCDCA; glycochenodeoxycholic acid; GDCA; glycodeoxycholic acid; GUDCA; glycoursodeoxycholic acid; HSA; hydrophobic surface area; HCA; hyocholic acid; NCA; nutriacholic acid; UCA; ursocholic acid; PSA; polar surface area; TCA; tauroc
Anti-nitric oxide production activity of isothiocyanates correlates with their polar surface area rather than their lipophilicity
Keywords: منطقه قطبی; Wasabi; Isothiocyanates; Nitric oxide; Structure–activity relationship; Polar surface area
An in vitro screening cascade to identify neuroprotective antioxidants in ALS
Keywords: منطقه قطبی; 5-LOX; 5-lipoxygenase; AAPH; 2,2â²-azobis(2-methylpropionamidine) dihydrochloride; ALS; amyotrophic lateral sclerosis; ARE; antioxidant response element; BBB; blood-brain barrier; CAPE; caffeic acid phenethyl ester; CNS; central nervous system; DCF; di
Physiochemical drug properties associated with in vivo toxicological outcomes
Keywords: منطقه قطبی; Toxicity; Polar surface area; C log P; Adverse events
Quantitative structure–uptake relationship of metal-organic frameworks as hydrogen storage material
Keywords: منطقه قطبی; Hydrogen adsorption; QSPR; Metal-organic frameworks; MOFs; Polar surface area
Efforts toward oral bioavailability in factor VIIa inhibitors
Keywords: منطقه قطبی; Factor VIIa inhibitor; Oral bioavailability; Parenteral lead; Selectivity; Serine protease; Polar surface area;
Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives
Keywords: منطقه قطبی; Centrally acting antihypertensives; Conformational analysis; Tautomerization; Solvent effect; pKa; Lipophilicity; Solubility; Absorption; Polar surface area
Ligand efficiency indices as guideposts for drug discovery
Keywords: منطقه قطبی; Drug Discovery; Pharmaceutical Science; Pharmacokinetics; Structure-activity relationship; Molecular weight; Polar surface area; Ligand-binding efficiency;