دانلود مقالات ISI درباره اصلاح posttranslational + ترجمه فارسی

PARP, transcription and chromatin modeling

Keywords: اصلاح posttranslational; ABCA1; ATP-binding cassette transporter A1; ADP-ribosylation; adenosine diphosphate ribosylation; ALC1; amplified in-liver-cancer 1; AR; androgen receptor; ARH3; ADP-ribosylhydrolase 3; ART; ADP-ribosyl transferase; ASF/SF2; alternative splicing factor/sp

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

A fluorogenic probe for imaging protein S-nitrosylation in live cells

Keywords: اصلاح posttranslational; Fluorescent probe; Imaging; S-nitrosylation; Posttranslational modification; Endothelial cell;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Rational design for the stability improvement of Armillariella tabescens β-mannanase MAN47 based on N-glycosylation modification

Keywords: اصلاح posttranslational; N-glycosylation; Posttranslational modification; Homology modeling; Enzyme stability; Molecular dynamics simulations;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

NMR characterization of weak interactions between RhoGDI2 and fragment screening hits

Keywords: اصلاح posttranslational; Fragment-based lead discovery; Rho guanine-nucleotide dissociation inhibitor 2; Transferred paramagnetic relaxation enhancement; Non-uniform sampling NMR; Posttranslational modification;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Observation of the side chain O-methylation of glutamic acid or aspartic acid containing model peptides by electrospray ionization-mass spectrometry

Keywords: اصلاح posttranslational; AA; acetic acid; CBB; commassie brilliant blue; CID; collision-induced dissociation; D; aspartic acid; E; glutamic acid; ESI-MS; electrospray ionization-mass spectrometry; EtOH; ethanol; FA; formic acid; iPrOH; isopropanol; LC-MS/MS; liquid chromatograp

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Clinical Implications Associated With the Posttranslational Modification-Induced Functional Impairment of Albumin in Oxidative Stress-Related Diseases

Keywords: اصلاح posttranslational; albumin; biomarker; oxidative stress; posttranslational modification; ligand binding; cysteine-34; liver disease; kidney disease; diabetes mellitus; HSA; human serum albumin; Cys-34; cysteine-34; BCAA; branched-chain amino acid; IMA; ischemia-modified alb

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

PDE4D phosphorylation: A coincidence detector integrating multiple signaling pathways

Keywords: اصلاح posttranslational; Phosphodiesterase; PDE4D; Phosphorylation; Posttranslational modification;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Redox signaling regulated by an electrophilic cyclic nucleotide and reactive cysteine persulfides

Keywords: اصلاح posttranslational; Electrophilic signaling; 8-Nitro-cGMP; NO; Redox signaling; 15d-PGJ2; 15-deoxy-Δ12,14-prostaglandin J2; ERK; extracellular signal-regulated kinase; GSH; glutathione; GST; glutathione S-transferase; HNE; 4-hydroxy-2-nonenal; iNOS; inducible type of NO syn

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Regulators in the DNA damage response

Keywords: اصلاح posttranslational; DNA damage response; Posttranslational modification; Noncoding RNA; microRNA; Long noncoding RNA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Posttranslational modulation of FoxO1 contributes to cardiac remodeling in post-ischemic heart failure

Keywords: اصلاح posttranslational; FoxO1; Posttranslational modification; Acetylation; Diabetes; Myocardial infarction; Heart failure; Cardiac remodeling;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Native chemical ligation between asparagine and valine: Application and limitations for the synthesis of tri-phosphorylated C-terminal tau

Keywords: اصلاح posttranslational; Native chemical ligation; Aspartimide formation; Posttranslational modification; Penicillamine ligation; Ligation at Asn;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

O-linked β-N-acetylglucosamine modification and its biological functions

Keywords: اصلاح posttranslational; O-GlcNAc; Posttranslational modification; Epigenetic regulation; Plants;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Kinases, tails and more: Regulation of PTEN function by phosphorylation

Keywords: اصلاح posttranslational; PTEN; Posttranslational modification; Phosphorylation; Kinases; CK2; GSK3; PLK3; Src; C-terminal tail; C2 domain;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Heterotrimeric G protein-mediated signaling and its non-canonical regulation in the heart

Keywords: اصلاح posttranslational; G protein; Heart; Non-canonical; Epigenetic; Regulation; MicroRNA; Posttranslational modification; Localization; Signal transduction

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Bortezomib Amplifies Effect on Intracellular Proteasomes by Changing Proteasome Structure

Keywords: اصلاح posttranslational; Multiple myeloma; Proteasome; Bortezomib; CTAB-PAGE; Posttranslational modification

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

High-resolution structures of the d-alanyl carrier protein (Dcp) DltC from Bacillus subtilis reveal equivalent conformations of apo- and holo-forms

Keywords: اصلاح posttranslational; CP; carrier protein; Dcp; d-alanyl CP; ACP; acyl CP; PCP; peptidyl CP; ArCP; aryl CP; ppant; 4′-phosphopantetheine; FA; fatty acid; PK; polyketide; NRP; non-ribosomal peptide; SeMet; selenomethionine; rmsd; root mean square deviation; Carrier protein; P

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Roles of active site residues in LodA, a cysteine tryptophylquinone dependent ε-lysine oxidase

Keywords: اصلاح posttranslational; Enzyme mechanism; Posttranslational modification; Quinoprotein; Amine oxidase; Cofactor; Redox enzyme

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Fatal hyperammonemia and carbamoyl phosphate synthetase 1 (CPS1) deficiency following high-dose chemotherapy and autologous hematopoietic stem cell transplantation

Keywords: اصلاح posttranslational; 3-OH-B; 3-Hydroxy-butyrate; AcAc; Acetoacetate; BW; Bodyweight; CA VA; Carbonic anhydrase VA; CPS1; Carbamoyl phosphate synthetase 1; HSCT; Hematopoietic stem cell transplantation; NAGS; N-acetyl-glutamate synthase; NCG; N-carbamyl-glutamate; OTC; Ornithi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of Torpor in the Gray Mouse Lemur: Transcriptional and Translational Controls and Role of AMPK Signaling

Keywords: اصلاح posttranslational; Posttranslational modification; Histone H3; Ribosomal initiation factors; Metabolic rate depression; AMP-activated protein kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

New insights into the posttranslational regulation of human cytosolic thioredoxin by S-palmitoylation

Keywords: اصلاح posttranslational; Posttranslational modification; Thioredoxin; PTP1B; S-palmitoylation; InsulinACSL, long-chain acyl-CoA synthetase; 2-BP, 2-bromopalmitate; FAS, fatty acid synthase; Gluc-N, glucosamine; GSNO, S-nitroso-glutathione; HAM, hydroxylamine; pNPP, para-Nitrophen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation and function of the human HSP90AA1 gene

Keywords: اصلاح posttranslational; Hsp90; heat shock protein 90; Grp94; glucose regulated protein 94; TRAP1; tumor necrosis factor associated protein 1; MHC1; major histocompatibility complex 1; PTM; posttranslational modification; TSS; transcription start site; HSE; heat shock element; TF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Proteogenomics of the human hippocampus: The road ahead

Keywords: اصلاح posttranslational; Genomics; Proteomics; Posttranslational modification; Protein–protein interaction; Human hippocampus

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Chemical structure and biological activity of a quorum sensing pheromone from Bacillus subtilis subsp. natto

Keywords: اصلاح posttranslational; Bacillus subtilis; Natto; Posttranslational modification; Quorum sensing;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation site

Keywords: اصلاح posttranslational; SOD2; manganese superoxide dismutase; ROS; reactive oxygen species; MD; molecular dynamics; PTM; posttranslational modification; Anh; acetic anhydride; MnTM-4-PyP; manganese(III) meso-tetrakis (N-methylpyridinium-4-yl) porphyrin.; Superoxide; Superoxide d

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteins

Keywords: اصلاح posttranslational; TLS; translesion synthesis; PCNA; proliferating cell nuclear antigen; pol; polymerase; PIP; PCNA-interacting peptide; RIR; Rev1-interacting region; UBM; ubiquitin binding motif; UBZ; ubiquitin binding zinc motif; polι; DNA polymerase iota; polη; DNA pol

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Modifications of RNA polymerase II CTD: Connections to the histone code and cellular function

Keywords: اصلاح posttranslational; RNA polymerase II; Histone; Transcription; Posttranslational modification; Histone code; CTD code;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

SOX family transcription factors involved in diverse cellular events during development

Keywords: اصلاح posttranslational; Sox gene; HMG box; Nucleocytoplasmic shuttling; Posttranslational modification; SOX-partner complex; Developmental functionAmh, anti-Müllerian hormone; CBP, cAMP-response element-binding protein (CREB)-binding protein; CRM1, chromosome region maintenance

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology

Keywords: اصلاح posttranslational; AAV; adeno-associated virus; AON; antisense oligonucleotide; bp; base pair; Ca2+;  calcium; CaMKII; Ca2+/calmodulin-dependent kinase II; Chr; chromosome; CK2; casein kinase 2; CMH4; hypertrophic cardiomyopathy, locus 4; cMyBP-C; cardiac myosin-binding pr

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

Azide-alkyne cycloaddition affording enzymatically tunable bisubstrate based inhibitors of histone acetyltransferase PCAF

Keywords: اصلاح posttranslational; Bisubstrate based inhibitor; Histone acetyltransferase; Enzyme inhibitor; Posttranslational modification; Protein acetylation;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Is Lys-Nɛ-acetylation the next big thing in post-translational modifications?

Keywords: اصلاح posttranslational; acetylome; acetyltransferase; posttranslational modification; regulation; signaling

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Analysis of PTP1B sumoylation

Keywords: اصلاح posttranslational; Signal transduction; Protein tyrosine phosphatases; Phosphorylation; Posttranslational modification; Sumoylation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Neutrophil Elastase in the capacity of the “H2A-specific protease”

Keywords: اصلاح posttranslational; H2Asp; H2A-specific protease; NE; Neutrophil Elastase; CL; cathepsin L; mESC; mouse embryonic stem cells; cH2A; cleaved histone H2A; PTM; posttranslational modification; MS; mass spectrometry; PBMC; peripheral blood monocytes; AQUA; Absolute Quantitation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

MauG, a diheme enzyme that catalyzes tryptophan tryptophylquinone biosynthesis by remote catalysis

Keywords: اصلاح posttranslational; Electron transfer; Posttranslational modification; Protein radical; Peroxidase; Oxygenase; High-valence iron

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Serine phosphorylation of CAPA pyrokinin in cockroaches—A taxon-specific posttranslational modification

Keywords: اصلاح posttranslational; MALDI-TOF-MS, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; PK, pyrokinin; PTM, posttranslational modificationInsect neuropeptides; Posttranslational modification; Phosphorylation; CAPA pyrokinin; MALDI-TOF mass spectrometr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A

Keywords: اصلاح posttranslational; S-adenosylmethionine (AdoMet); Protein lysine methylation; Elongation factor; Methyltransferase; Posttranslational modification;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A fluorescence-based assay to monitor autopalmitoylation of zDHHC proteins applicable to high-throughput screening

Keywords: اصلاح posttranslational; Protein palmitoylation; High-throughput screening; Autopalmitoylation; Posttranslational modification; zDHHC proteins

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Methylation of translation elongation factor 1A by the METTL10-like See1 methyltransferase facilitates tombusvirus replication in yeast and plants

Keywords: اصلاح posttranslational; Tomato bushy stunt virus; Virus-host interaction; Yeast; Plant; Replication; Posttranslational modification; Methyltransferase; Translation elongation factor 1A; Nodaviruses; Tombusviruses; Host factor;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Substrate recognition in selective autophagy and the ubiquitin-proteasome system

Keywords: اصلاح posttranslational; Protein degradation; Selective autophagy; Ubiquitin-proteasome system; Ubiquitination; Substrate recognition; Posttranslational modification;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Associate editor: B. TeicherEpigenetic targets and drug discovery: Part 1: Histone methylation

Keywords: اصلاح posttranslational; Epigenetics; Histone methylation; Inhibitor; Chemical probe; Cancer; PTM; posttranslational modification; HMTs; histone methyltrans-ferases; SET; Suv39, E(z) and Trithorax; SUV39; Su(var)3-9; SUV420; histone-lysine N-methyltransferase SUV420; G9a; euchrom

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of ubiquitin-modified lysine residues and novel phosphorylation sites on eukaryotic initiation factor 2B epsilon

Keywords: اصلاح posttranslational; DMEM; Dulbecco's modified Eagle's medium; eIF; eukaryotic initiation factor; HECT; homologous to E5-AP carboxyl terminus; LC; liquid chromatography; MS/MS; tandem mass spectrometry; NEDD4; neural precursor cell expressed, developmentally down-regulate

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Disease-associated single amino acid mutation in the calf-1 domain of integrin α3 leads to defects in its processing and cell surface expression

Keywords: اصلاح posttranslational; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; mAb; monoclonal antibody; pAb; polyclonal antibody; PBS; phosphate-buffered saline; Glycosylation; Posttranslational modification; Basement membrane; Laminin; Tetraspanin; CD151;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Citrullination of TNF-α by peptidylarginine deiminases reduces its capacity to stimulate the production of inflammatory chemokines

Keywords: اصلاح posttranslational; TNF; Citrullination; Cytokine; IL-1β; Posttranslational modification; Arg; arginine; CHX; cycloheximide; Cit; citrulline; [Cit]TNF-α; citrullinated TNF-α; DMEM; Dulbecco's modified Eagle's medium; ELISA; enzyme-linked immunosorbent assay; E/S; enzy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Covalent inhibition of SUMO and ubiquitin-specific cysteine proteases by an in situ thiol-alkyne addition

Keywords: اصلاح posttranslational; Posttranslational modification; Cysteine peptidase; Suicide inhibitor; Catalytic triad; Electrophile;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription

Keywords: اصلاح posttranslational; Transcription; RNA polymerase II; Carboxy-terminal domain; Posttranslational modification; Phosphorylation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of ADP-ribosylation sites of CD38 mutants by precursor ion scanning mass spectrometry

Keywords: اصلاح posttranslational; ADP-ribosylation; CD38; Precursor ion scanning; Mass spectrometry; Posttranslational modification;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Posttranslational modifications of cardiac troponin T: An overview

Keywords: اصلاح posttranslational; AMI; acute myocardial infarction; ASK1; apoptosis signal-regulating kinase 1; CaMK II; Ca2 +/calmodulin-dependent protein kinase II; cTnT/I/C; cardiac troponin T, I, C; ESRD; end-stage renal disease; GFC; gel filtration chromatography; HF; heart failure;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization of the peptidylglycine α-amidating monooxygenase (PAM) from the venom ducts of neogastropods, Conus bullatus and Conus geographus

Keywords: اصلاح posttranslational; Posttranslational modification; Conotoxins; Peptidylglycine α-amidating monooxygenase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

HIPK2 catalytic activity and subcellular localization are regulated by activation-loop Y354 autophosphorylation

Keywords: اصلاح posttranslational; e.v.; empty vector; IF; immunofluorescence; IP; immunoprecipitation; IVT; in vitro translation; moAb; monoclonal antibody; purvA; purvalanol A; TCE; total cell extracts; WB; Western blotting; HIPK2; Posttranslational modification; Phosphorylation; Activat

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

DNA-dependent SUMO modification of PARP-1

Keywords: اصلاح posttranslational; PARP-1; SUMO; Posttranslational modification; DNA binding; DNA repair; Transcription;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker

Keywords: اصلاح posttranslational; Alzheimer's disease; Tauopathy; Pin1; Microtubule-associated protein tau; Proteomics; Phosphorylation; Acetylation; Posttranslational modification; Biomarker;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه