Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Polyozellin; p-Terphenyl; Suzuki-Miyaura coupling; Ullmann reaction;
مقالات ISI پرولیلو الیگوپپتیداز (ترجمه نشده)
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Keywords: پرولیلو الیگوپپتیداز; Beer colloidal stability; Chill and permanent haze; Ceramic tubular membrane; PVPP; Prolyl oligopeptidase;
Rational design of metalloenzymes: From single to multiple active sites
Keywords: پرولیلو الیگوپپتیداز; UAAs; unnatural amino acids; Rd; rubredoxin; EPR; electron paramagnetic resonance; Az; azurin; SOR; superoxide reductase; PDB; protein data bank; 6-PGLac; 6-phosphogluconolactonase; H-bond; hydrogen-bond; NIR; nitrite reductase; ET; electron transfer; 3SC
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Synaptic plasticity; Behaviour; Anxiety; Depression;
Keywords: پرولیلو الیگوپپتیداز; ACADM; medium chain acyl-CoA dehydrogenase; ACADVL; very long chain acyl-CoA dehydrogenase; ACC; acetyl-coenzyme A carboxylase alpha; ACSL1; acyl-CoA synthetase long-chain family member 1; ADIPOR2; adiponectin receptor 2; Akt; protein kinase B; AK2; Adeny
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; KYP-2047; JTP-4819; Acetylcholine; Hippocampus; Cortex;
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; SUAM-14746; Human gastric cancer cells; Cell cycle arrest; Quiescent G0 state;
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Glyceraldehyde-3-phosphate dehydrogenase; NB-1 cells; Cytosine arabinoside; Cell death; POP; prolyl oligopeptidase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; Ara-C; cytosine arabinoside; rhPOP; recombinant human POP; PLA; pro
Keywords: پرولیلو الیگوپپتیداز; Abz; 2-aminobenzoyl; BNA; β-naphthylamide; CD; circular dichroism; DLS; dynamic light scattering; DSC; differential scanning calorimetry; DTT; dithiothreitol; DTNB; 5,5'-dithiobis(2-nitrobenzoic acid); EDTA; ethylenediaminetetraacetic acid; EDDnp; N-(2,4
Molecular cloning and the expression pattern of AePOPB involved in the α-amanitin biosynthesis in Amanita exitialis fruiting bodies
Keywords: پرولیلو الیگوپپتیداز; POPase; prolyl oligopeptidase; RACE; rapid amplification of cDNA ends; qRT-PCR; quantitative real-time PCR; GSDS; Gene Structure Display Server; pI; isoelectric point; Mw; molecular weight; NCBI; National Center for Biotechnology Information; Cyclic pepti
Identification and characterization of a novel prolyl oligopeptidase in filarial parasite Setaria cervi
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; ER stress; Calcium; Mitochondria; Apoptosis; Parasite;
Identification of two isoforms of Pop in the domestic silkworm, Bombyx mori: Cloning, characterization and expression analysis
Keywords: پرولیلو الیگوپپتیداز; Aph; acylpeptide hydrolase; AA; alternative acceptor site; AD; alternative donor site; AS; alternative splicing; ANCE; angiotensin-converting enzyme; Ang I; angiotensin I; B. mori; Bombyx mori; BSA; bovin serum albumin; DTT; dithiothreitol; E. coli; Esche
Effect of oxidation of the non-catalytic β-propeller domain on the substrate specificity of prolyl oligopeptidase from Pleurotus eryngii
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Substrate specificity; Sulfoxidation; β-propeller domain; Site-specific mutation; pNA; para-nitroanilide; POP; prolyl oligopeptidase; DTT; dithiothreitol;
Purification, characterization and the use of recombinant prolyl oligopeptidase from Myxococcus xanthus for gluten hydrolysis
Keywords: پرولیلو الیگوپپتیداز; Serine protease; Prolyl oligopeptidase; Enzymatic hydrolysis;
The prolyl oligopeptidase inhibitor IPR19 ameliorates cognitive deficits in mouse models of schizophrenia
Keywords: پرولیلو الیگوپپتیداز; Schizophrenia; Prolyl oligopeptidase; Cognition; Peptidomimetic; Animal model;
Activity modulation of the oligopeptidase B from Serratia proteamaculans by site-directed mutagenesis of amino acid residues surrounding catalytic triad histidine
Keywords: پرولیلو الیگوپپتیداز; Oligopeptidase B; Serratia proteamaculans; Inter-domain interface; Comparative modelling; Site-specific mutagenesis; Enzyme engineering; OpdB; oligopeptidase B; POP; prolyl oligopeptidase; PSP; protease from Serratia proteamaculans; SDS-PAGE; sodium dod
Synthesis and biological evaluation of novel 123I-labeled 4-(4-iodophenyl)butanoyl-l-prolyl-(2S)-pyrrolidines for imaging prolyl oligopeptidase in vivo
Keywords: پرولیلو الیگوپپتیداز; 123I-radiotracer; Prolyl oligopeptidase; Biodistribution; InflammationPOP, Prolyl oligopeptidase; PD, Parkinson's disease; MMP, matrix metalloproteinases; LPS, lipopolysaccharide
Alteration of prolyl oligopeptidase and activated α-2-macroglobulin in multiple sclerosis subtypes and in the clinically isolated syndrome
Keywords: پرولیلو الیگوپپتیداز; Multiple sclerosis; Prolyl oligopeptidase; α-2-Macroglobulin; Inflammation; Cell signalling; Biomarkers;
Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP/prolyl oligopeptidase (PREP)-selectivity
Keywords: پرولیلو الیگوپپتیداز; Fibroblast activation protein-α; FAP; Seprase; DPP IV, DPP4; PREP; Prolyl oligopeptidase; Val-boroPro; PT-100; Talabostat
Comparative analysis of the substrate preferences of two post-proline cleaving endopeptidases, prolyl oligopeptidase and fibroblast activation protein α
Keywords: پرولیلو الیگوپپتیداز; ACN; acetonitrile; APCE; antiplasmin-cleaving enzyme; DMSO; dimethylsulfoxide; DPA; Nb-(2,4-dinitrophenyl)-l-2,3-diaminopropionic acid; DPPIV; dipeptidyl peptidase IV; FAP; fibroblast activation protein; IQFP; internally quenched fluorogenic probes; MALDI
Coupled motions during dynamics reveal a tunnel toward the active site regulated by the N-terminal α-helix in an acylaminoacyl peptidase
Keywords: پرولیلو الیگوپپتیداز; Acylaminoacyl peptidase; Molecular dynamics simulations; Prolyl oligopeptidase; Correlated motions; Extremophilic enzyme; Conformational changes
The effect of prolyl oligopeptidase inhibition on extracellular acetylcholine and dopamine levels in the rat striatum
Keywords: پرولیلو الیگوپپتیداز; Acetylcholine; Dopamine; Prolyl oligopeptidase; Microdialysis; Rat
Four day inhibition of prolyl oligopeptidase causes significant changes in the peptidome of rat brain, liver and kidney
Keywords: پرولیلو الیگوپپتیداز; Peptidomics; Peptide metabolism; Protein convertases; Prolyl oligopeptidase; ACBP; Acyl-CoA-binding protein; NEI; Neuropeptide-glutamic acid-isoleucine; PC; Pro-protein convertase; PREP; Prolyl oligopeptidase; VEGF; Vascular endothelial growth factor;
Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Mutagenesis; Molecular dynamics; Crystallography; Gating mechanism;
Inhibition of prolyl oligopeptidase by KYP-2047 fails to increase the extracellular neurotensin and substance P levels in rat striatum
Keywords: پرولیلو الیگوپپتیداز; Neurotensin; Substance P; Prolyl oligopeptidase; Microdialysis; Radioimmunoassay;
Prolyl oligopeptidase participates in cell cycle progression in a human neuroblastoma cell line
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; SUAM-14746; NB-1 cells; Growth inhibition; Cell cycle; G0/G1 arrest;
Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9
Keywords: پرولیلو الیگوپپتیداز; DPP-IV; dipeptidyl peptidase IV; DPP; dipeptidyl peptidase; POP; prolyl oligopeptidase; H-Gly-Pro-pNA; HGly-Pro-p-nitroanilide; DTT; dithiothreitol; AUC; analytical ultracentrifugation; CD; circular dichroism; FAP; fibroblast activation protein; ADA; aden
Angiotensin-I-converting enzyme and prolyl endopeptidase inhibitory peptides from natural sources with a focus on marine processing by-products
Keywords: پرولیلو الیگوپپتیداز; ACE; angiotensin I-converting enzyme; PEP; prolyl endopeptidase; PO; prolyl oligopeptidase; Hip-His-Leu; hippuryl-L-histidyl-L-leucine; SHRs; spontaneously hypertensive rats; Angiotensin I-converting enzyme (ACE-1); Prolyl endopeptidase (PEP); Hypertensio
Subchronic administration of rosmarinic acid, a natural prolyl oligopeptidase inhibitor, enhances cognitive performances
Keywords: پرولیلو الیگوپپتیداز; Rosmarinic acid; Prolyl oligopeptidase; Cognitive performance; Morris water maze
Flavonoids with prolyl oligopeptidase inhibitory activity isolated from Scutellaria racemosa Pers
Keywords: پرولیلو الیگوپپتیداز; Scutellaria racemosa Pers; Prolyl oligopeptidase; POP inhibition; Dipeptidyl peptidase; DPP IV inhibition
Increased prolyl endopeptidase activity in human neoplasia
Keywords: پرولیلو الیگوپپتیداز; Prolyl endopeptidase; Prolyl oligopeptidase; PEP; Cancer; Tumor markers; Bioactive peptides
Conversion of the anti-tumor agent tasidotin (ILX651) to its active metabolite by prolyl oligopeptidase
Keywords: پرولیلو الیگوپپتیداز; Tasidotin; ILX651; Prolyl oligopeptidase; Prolyl endopeptidase; Solid tumors; Microtubule inhibitor
Research ArticlePreservation of basal AcSDKP attenuates carbon tetrachloride-induced fibrosis in the rat liver
Keywords: پرولیلو الیگوپپتیداز; AcSDKP; N-acetyl-seryl-aspartyl-lysyl-proline; CCl4; carbon tetrachloride; POP; prolyl oligopeptidase; Tβ4; thymosin-β4; ACE; angiotensin converting enzyme; ECM; extracellular matrix; TGF-β1; transforming growth factor-β1; HSC; hepatic stellate cell;
Prolyl oligopeptidase of Trypanosoma brucei hydrolyzes native collagen, peptide hormones and is active in the plasma of infected mice
Keywords: پرولیلو الیگوپپتیداز; Trypanosoma brucei; Prolyl oligopeptidase; Sleeping sickness; Peptide hormone; Collagen hydrolysis; Prolyl oligopeptidase inhibitors
Using peptidyl aldehydes in activity-based proteomics
Keywords: پرولیلو الیگوپپتیداز; Aldehydes; Peptides; Activity-based proteomics; Prolyl oligopeptidase
A new side opening on prolyl oligopeptidase revealed by electron microscopy
Keywords: پرولیلو الیگوپپتیداز; POP; prolyl oligopeptidase; IP3; inositol-1,4,5-P3; Z; benzyloxycarbonyl; ZPP; Z-l-prolyl-l-prolinal; EM; electron microscopy; MD; molecular dynamics; Rf; migration rate; Ahx; epsilon-aminocaproyl; Prolyl oligopeptidase; Electron microscopy; Native electr
Putative “acylaminoacyl” peptidases from Streptomyces griseus and S. coelicolor display “aminopeptidase” activities with distinct substrate specificities and sensitivities to reducing reagent
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Phenylalanylaminopeptidase; Serine peptidase; Actinomycete; Substrate recognition property
Combination of snap freezing, differential pH two-dimensional reverse-phase high-performance liquid chromatography, and iTRAQ technology for the peptidomic analysis of the effect of prolyl oligopeptidase inhibition in the rat brain
Keywords: پرولیلو الیگوپپتیداز; Peptidomics; Sample preparation; 2D LC; ESI-MS/MS; iTRAQ; Prolyl oligopeptidase; Z-Pro-Prolinal
Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; GAP-43; α-Synuclein; Mood stabilizer; Learning and memory; Synaptic plasticity; Growth cones; Adenoviral transduction; Protein–protein interaction
Effects of memantine on soluble Îβ25-35-induced changes in peptidergic and glial cells in Alzheimer's disease model rat brain regions
Keywords: پرولیلو الیگوپپتیداز; Alzheimer's disease; memantine; peptidergic system; dendritic spine; glial cells; AD; Alzheimer's disease; ANOVA; analysis of variance; APP; amyloid-β precursor protein; Aβ; amyloid-β; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; EP 24.1
Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP)
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Serine protease; Pyridone; pyrazinone; Pyrrolidine; Prolyl endopeptidase
Localization of post-proline cleaving peptidases in Tenebrio molitor larval midgut
Keywords: پرولیلو الیگوپپتیداز; Digestive peptidase; Prolyl oligopeptidase; Tenebrio molitor; Serine peptidase; Yellow mealwormAM, anterior midgut; BBMV, brush border membrane vesicles; DFP, diisopropylfluorophosphate; DTT, dithiothreitol; E-64, l-transepoxysuccinyl-l-leucylamido(4-guan
Prolyl oligopeptidase stimulates the aggregation of α-synuclein
Keywords: پرولیلو الیگوپپتیداز; Parkinson's disease; Amyloid fibrils; Prolyl oligopeptidase; Intrinsically unstructured protein
Oligopeptidase B: A processing peptidase involved in pathogenesis
Keywords: پرولیلو الیگوپپتیداز; Oligopeptidase B; Prolyl oligopeptidase; Carboxyl dyad; Peptidase inhibitors
2(S)-(Cycloalk-1-enecarbonyl)-1-(4-phenyl-butanoyl)pyrrolidines and 2(S)-(aroyl)-1-(4-phenylbutanoyl)pyrrolidines as prolyl oligopeptidase inhibitors
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; α,β-Unsaturated carbonyl group; 2-Thiophene; 1-Cyclopentene
Characterization of prolyl oligopeptidase from hyperthermophilic archaeon Thermococcus sp. NA1
Keywords: پرولیلو الیگوپپتیداز; prolyl oligopeptidase; hyperthermophile; archaea; Thermococcus; autodegradation
Suggested functions for prolyl oligopeptidase: A puzzling paradox
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Serine protease; Inositolphosphate; Brain; Neuropeptide
On the role of prolyl oligopeptidase in health and disease
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Neuropeptide metabolism; Memory and learning; Inositol cycle; Substance P; Arginine-vasopressin; Thyroliberin; GonadoliberinACD, active coeliac disease; ACE, angiotensin-coverting enzyme; ACPH, acylaminoacyl peptidase; AD, Alzheimer
An introduction of a pyridine group into the structure of prolyl oligopeptidase inhibitors
Keywords: پرولیلو الیگوپپتیداز; Prolyl oligopeptidase; Inhibitor; Pyridine
Catabolism of the octadecaneuropeptide ODN by prolyl endopeptidase: Identification of an unusual cleavage site
Keywords: پرولیلو الیگوپپتیداز; DBI; diazepam-binding inhibitor; hUII; human urotensin II; ODN; octadecaneuropeptide; PEP; prolyl endopeptidase; Prolyl oligopeptidase; EC 3.4.21.26; PEP; Neuropeptide catabolism; Endozepines; Urotensin II;