دانلود مقالات ISI درباره Pvhl + ترجمه فارسی

تومور مزانشیمی خارج سلولی در آنژیوژنز

Tumor-derived extracellular vesicles in angiogenesis

Keywords: AMPK; AMP-activated protein kinase; ARF6; ADP-ribosylation factor 6; AKT; protein kinase B; BBB; blood brain barrier; bFGF; b-fibroblast growth factors; b-FGFR; b-fibroblast growth factors receptor; ccRCC; clear cell renal cell carcinoma; ECs; endothelial

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

هدف قرار دادن درمان فاکتورهای رونویسی آن کربن توسط محصولات طبیعی در سرطان چشم

Therapeutic targeting of oncogenic transcription factors by natural products in eye cancer

Keywords: 2,5-DXP; 2,5-diketopiperazine; ACC; adenoid cystic carcinomas; BBR; berberine; BET; bromodomain and extraterminal; CA; chebulagic acid; CPT; camptothecin; EMT; epithelial-mesenchymal transition; GSK3; glycogen synthase kinase 3-; HCC; hepatocellular carci

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

توالی سلولی مرگ سلولی برنامه ریزی شده 5

Cellular functions of programmed cell death 5

Keywords: PDCD5; programmed cell death 5; Treg; regulatory T cell; CK2; casein kinase 2; rhPDCD5; recombinant human PDCD5; PDCD5tg; PDCD5 transgenic mice; HDAC3; histone deacetylase 3; CCT; cytosolic chaperonin containing tailless complex polypeptide 1; EAE; autoim

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

ارزش تشخیصی ماسپین در تشخیص آدنوکارسینومای از اپیتلیوم خوشخیم صفراوی در بیوپسی مجرای صفراوی آندوسکوپی

Diagnostic value of maspin in distinguishing adenocarcinoma from benign biliary epithelium on endoscopic bile duct biopsy

Keywords: Maspin; S100P; pVHL; IMP3; Bile duct; Biopsy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

نقش مس در رگرسیون هیپرتروفی قلبی

Role of copper in regression of cardiac hypertrophy

Keywords: Copper; Cardiac hypertrophy; CCO; Angiogenesis; VEGFRs; HIF-1; ANG-1; angiopoietin-1; ANG-2; angiopoietin-2; ANP; atrial natriuretic peptide; ATOX1; antioxidant 1; ATP; adenosine triphosphate; BNP; B-type natriuretic peptide; BNIP3; BCL2/adenovirus E1B 19

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

تمایز ایمونوهیستوشیمیایی بین کلانژیوکارسینوم داخل کبد و آدنوکارسینوم مدول پانکراس

Immunohistochemical distinction between intrahepatic cholangiocarcinoma and pancreatic ductal adenocarcinoma

Keywords: Intrahepatic cholangiocarcinoma; Pancreatic ductal adenocarcinoma; S100P; pVHL; MUC5AC; CK17; IMP3; Maspin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

بررسی عوامل هپاتوسیک در بیماری کبد و کارسینوم سلول های کبدی: درک در حال حاضر و جهت آینده

ReviewHypoxia inducible factors in liver disease and hepatocellular carcinoma: Current understanding and future directions

Keywords: HIFs; hypoxia inducible transcription factors; pO2; oxygen pressure; HREs; hypoxia responsive elements; PHD; prolyl hydroxylase domain-containing protein; FIH; factor inhibiting HIF; pVHL; von Hippel-Lindau tumour suppressor; mTOR; mechanistic target of r

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Downregulation of HIF complex in the hypothalamus exacerbates diet-induced obesity

Keywords: ACTH; Adrenocorticotropic Hormone; ARC; Arcuate Nucleus; AgRP; Agouti-Related Peptide; ARNT; Aryl Hydrocarbon Receptor Nuclear Translocator; BAT; Brow Adipose Tissue; DIO; Diet-induced Obesity; FIH; Factor Inhibiting HIF-1α; GFAP; Glial Fibrillary Acidic

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Paving the Rho in cancer metastasis: Rho GTPases and beyond

Keywords: ADP; adenosine diphosphate; AMP; adenosine monophosphate; AMT; amoeboid-mesenchymal transition; APC; adenomatosis polyposis coli; Arp2/3; actin related protein 2/3; Cdc42; cell division control protein 42 homolog; CK1; casein kinase 1; COX-2; cyclooxygena

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2018 سفارش ترجمه

Systemic Sunitinib Malate Treatment for Advanced Juxtapapillary Retinal Hemangioblastomas Associated with von Hippel-Lindau Disease

Keywords: CNS; central nervous system; HIFα; hypoxia-inducible factor alpha; OD; right eye; OS; left eye; PDGF; platelet-derived growth factor; pVHL; protein von Hippel-Lindau; RCH; retinal capillary hemangioblastomas; TKI; tyrosine kinase inhibitor; VEGF; vascula

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complex

Keywords: HIF2α; hypoxia-inducible factor 2α; VHL; Von Hippel-Lindau; pVHL; von Hippel Lindau tumor suppressor protein; CODD; C-terminal oxygen-dependent degradation domain; 3D; three-dimensional; ARNT; aryl hydrocarbon receptor nuclear translocator; HRE; hypox

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Traveling Rocky Roads: The Consequences of Transcription-Blocking DNA Lesions on RNA Polymerase II

Keywords: RNAP2; RNA polymerase II; TBL; transcription-blocking lesion; TCR; transcription-coupled DNA repair; TFIIS; transcription factor IIS; CS; Cockayne syndrome; CSB; Cockayne syndrome B; DUB; de-ubiquitylating enzyme; pVHL; von Hippel-Lindau tumor suppresso

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticlepVHL mediates K63-linked ubiquitination of IKKβ, leading to IKKβ inactivation

Keywords: IKKβ; pVHL; Ubiquitination;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Catalytic-independent inhibition of cIAP1-mediated RIP1 ubiquitination by EGLN3

Keywords: cIAP; cellular inhibitor of apoptosis protein; DFX; Desferrioxamine; DMOG; dimethyl oxalylglycine; EGLN; Caenorhabditis elegans gene egl-9; HA; hemagglutinin; HEK293 cells; human embryonic kidney 293 cells; IB; immunoblotting; IP; immunoprecipitation; HIF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Oxygen regulates proliferation of neural stem cells through Wnt/β-catenin signalling

Keywords: ARNT; aryl hydrocarbon receptor nuclear translocator; BrdU; 5-bromo-2′-deoxyuridine; GFAP; glial fibrillary acidic protein; Hif; hypoxia-inducible factor; IWP; inhibitor of Wnt production; IWR; inhibitor of Wnt response; Map2; microtubule-associated pro

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

pVHL interacts with Ceramide kinase like (CERKL) protein and ubiquitinates it for oxygen dependent proteasomal degradation

Keywords: pVHL; the Von Hippel-Lindau tumor suppressor protein; ECV complex; elongin B/C-Cul2-VHL protein complex; PHD1-3; prolyl hydroxylase domain proteins 1-3; UPS; ubiquitin proteasome system; HIFs; hypoxia inducible factors; ROS; reactive oxygen species;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The acquired radioresistance in HeLa cells under conditions mimicking hypoxia was attenuated by a decreased expression of HIF subunit genes induced by RNA interference

Keywords: HIF; hypoxia inducible factor; VEGF; vascular endothelial growth factor; LET; linear energy transfer; CSC; cancer stem cell; ODD; oxygen dependent degradation domain; pVHL; Von Hippel-Lindau gene product; PDGF; Platelet-Derived Growth Factor; CXCR4; C-X

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells

Keywords: PEITC; phenethyl isothiocyanate; PAGE; polyacrylamide gel electrophoresis; PBS; phosphate-buffered saline; SDS; sodium dodecyl sulphate; HIF-1α; hypoxia-inducible factor-1; VEGF; vascular endothelial growth factor; uPA; urokinase-type plasminogen activat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

MgcRacGAP, a cytoskeleton regulator, inhibits HIF-1 transcriptional activity by blocking its dimerization

Keywords: HIF-1; hypoxia inducible factor 1; ARNT; aryl hydrocarbon receptor nuclear translocator; MgcRacGAP; male germ cell Rac GTPase activating protein; bHLH; basic helix-loop-helix; PAS; Per-ARNT-Sim; ODD; oxygen dependent degradation; pVHL; von Hippel-Li

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Hypoxia-inducible factor 1α mediates the down-regulation of superoxide dismutase 2 in von Hippel–Lindau deficient renal clear cell carcinoma

Keywords: pVHL; HIF-1α; ROS; SOD2

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Diagnostic utility of von Hippel-Lindau gene product, maspin, IMP3, and S100P in adenocarcinoma of the gallbladder

Keywords: Adenocarcinoma; Gallbladder; pVHL; Maspin; IMP3; S100P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Lack of a Functional VHL Gene Product Sensitizes Renal Cell Carcinoma Cells to the Apoptotic Effects of the Protein Synthesis Inhibitor Verrucarin A

Keywords: cFLIP; cellular-FLICE inhibitory protein; CHX; cycloheximide; CCRCC; clear cell renal cell carcinoma; HTS; high-throughput screen; pVHL; VHL gene protein product; SG; stress granule; VA; verrucarin A or muconomycin A; VHL; von Hippel-Lindau; VHL-/-; VHL-d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Aminoguanidine normalizes ET-1-induced aortic contraction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats by suppressing Jab1-mediated increase in ETA-receptor expression

Keywords: AG; aminoguanidine; AGEs; advanced glycation end-products; CML; N epsilon-(carboxymethyl) lysine; ECE1; endothelin converting enzyme; ERK; extracellular signal-regulated kinase; ET-1; endothelin-1; ETA-R; endothelin type A receptor; ETB-R; endothelin type

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Identification and Functional Characterization of pVHL-Dependent Cell Surface Proteins in Renal Cell Carcinoma

Keywords: ASAP ratio; automated statistical analysis on protein ratio; ccRCC; clear cell renal cell carcinoma; ChIP; chromatin immunoprecipitation; CSC; cell surface capturing; DMOG; dimethyloxalyl glycine; HIF; hypoxia-inducible factor; HRE; hypoxia response eleme

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms

Keywords: BACK; BTB and C-terminal kelch; bHLH; basic helix-loop-helix; BTB; broad-complex/tramtrack/bric-a-brac; HIF; hypoxia-inducible factor; HRE; hypoxia-responsive element; KLHL20; kelch-like 20; ODD; oxygen-dependent degradation; PAS; PER-ARNT-SIM; pVHL;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Endogenous 2-oxoglutarate levels impact potencies of competitive HIF prolyl hydroxylase inhibitors

Keywords: 2-OG; 2-oxoglutarate; DFO; desferrioxamine; HPH; HIF prolyl hydroxylase; pVHL; von Hippel-Lindau protein; SPA; scintillation proximity assay; Hif prolyl hydroxylase; 2-Oxoglutarate; von Hippel-Lindau protein; Scintillation proximity assay;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleOverexpression of von Hippel-Lindau protein synergizes with doxorubicin to suppress hepatocellular carcinoma in mice

Keywords: HCC; hepatocellular carcinoma; HIF; hypoxia inducible factor; HRE; hypoxia-response-element; VHL; von Hippel-Lindau gene; pVHL; VHL tumor suppressor protein; VEGF; vascular endothelial growth factor; NF-κB; nuclear factor-κB; TNF-α; tumor necrosis fa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

S100P, von Hippel-Lindau gene product, and IMP3 serve as a useful immunohistochemical panel in the diagnosis of adenocarcinoma on endoscopic bile duct biopsy

Keywords: Bile duct; Adenocarcinoma; Biopsy; S100P; pVHL; IMP3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth

Keywords: EGLN; Egl-9 homologue; HIF-1; hypoxia-inducible factor-1; HNSCC; head and neck squamous cell carcinoma; PHD; prolyl hydroxylation domain protein; pVHL; von Hippel-Lindau protein; TMA; tissue microarray; RT-PCR; real-time PCR; Colon carcinoma; HIF-1α; Hyp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors

Keywords: Nitric oxide; PHD activity; PHD2; HIF-1; pVHL; Feedback loop

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Transcriptional activation of hypoxia-inducible factor-1α by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1

Keywords: HIF-1; hypoxia-inducible factor-1; ODD; oxygen-dependent degradation; FIH-1; factor inhibiting HIF-1; HDAC; histone deacetylase; HRE; hypoxia-response element; C-TAD; C-terminal activating domain; ID; inhibitory domain; TSA; trichostatin A; pVHL; von Hipp

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Hammerhead ribozyme targeting human hypoxia inducible factor-1α gene effectively attenuates HeLa xenograft tumors

Keywords: CMV; cytomegalovirus; DMEM; Dulbeco's modified eagle medium; HIF-l; hypoxia inducible factor l; HRE; hypoxia-responsive element; mRNA; messenger RNA; mRz; mutant ribozyme; PAS; Per/Arnt/Sim; PBS; phosphate buffer solution; PCR; polymerase chain reaction;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Intermittent hypoxia regulates RNA polymerase II in hippocampus and prefrontal cortex

Keywords: intermittent hypoxia; hippocampus; prolyl hydroxylase; RNA polymerase II; PC12 cells; CTD; C-terminal domain; Cul2; cullin 2; cyt; cytoplasmic extract; HA; hemagglutinin; HP; hydroxylated proline; IH; intermittent hypoxia; nuc; nuclear extract; PC12; pheo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2

Keywords: pVHL; Kinesin-2; FRAP; Mobility fraction; Hemangioblastoma;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

VDUP1 mediates nuclear export of HIF1α via CRM1-dependent pathway

Keywords: CRM1, chromosome region maintenance 1; HDAC, histone deacetylase; HIF1α, hypoxia-inducible factor 1α; NES, nuclear export signal; pVHL, von Hippel–Lindau protein; SAHA, suberoylanilide hydroxamic acid; VDUP1, vitamin D3 up-regulated protein 1HIF1α; pVHL;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

The role of ascorbate in the modulation of HIF-1α protein and HIF-dependent transcription by chromium(VI) and nickel(II)

Keywords: CA9; carbonic anhydrase 9; DHA; dehydroascorbate; HIF; hypoxia-inducible transcription factor; HRE; HIF response element; 2-OG; 2-oxoglutarate; ROS; reactive oxygen species; pVHL; von Hippel-Lindau protein; Ascorbate; Chromium(VI); Nickel(II); HIF-1α;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL

Keywords: IRP2; iron regulatory protein 2; IRE; iron-responsive element; HIF; hypoxia inducible factor; pVHL; von Hippel-Lindau protein; GFP; green fluorescent protein; FAC; ferric ammonium citrate; DFO; desferrioxamine; DMOG; dimethyl-oxalyl-glycine; IP; immunop

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

When hypoxia signalling meets the ubiquitin-proteasomal pathway, new targets for cancer therapy

Keywords: ARD1; arrest defective-1 protein; ARNT; aryl hydrocarbon receptor nuclear translocator; bHLH; basic helix loop helix; CBP; CREB binding protein; CPT; camptothecin; C-TAD; C-terminal transactivation domain; FIH-1; factor inhibiting HIF-1; HAT; histone acet

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Virus-based reporter systems for monitoring transcriptional activity of hypoxia-inducible factor 1

Keywords: HIF-1; hypoxia-inducible factor 1; HRE; hypoxia response element; VEGF; vascular endothelial growth factor; ENO1; enolase 1; LDHA; lactate dehydrogenase A; PGK1; phosphoglycerate kinase 1; pVHL; Von Hippel Lindau protein; LTR; long terminal repeat; SIN; s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1α accumulation-Implications for prolyl hydroxylase activity and iron

Keywords: Hypoxia; PHD activity; pVHL; NO donors; Intracellular free iron;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Novel antibody tags from the rat lysosomal protein RT1.DM for immunodetection of recombinant proteins

Keywords: mAb; monoclonal antibody; aa; amino acids; MBP; maltose-binding-protein; GST; glutathione S-transferase; pVHL; von Hippel-Lindau protein; MHC; major histocompatibility complex; SUMO4; small ubiquitin related modifier-4; RT1.DM; rat MHC locus for DM; SDSâ€

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Antioxidant defenses in the preterm lung: role for hypoxia-inducible factors in BPD?

Keywords: Ang-1 to -4; angiopoietin 1 to 4; AOE(s); antioxidant enzyme(s); ARD-1; HIF acetylase; ARNT; aryl hydrocarbon nuclear translocator; BPD; bronchopulmonary dysplasia; CAT; catalase; CTAD and NTAD; C- and N-terminal transactivation domain, respectively; CuZn

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه