Keywords: BMI; Body mass index; CVD; Cardiovascular disease; CAR; Constitutive androstane receptor; GFR; Glomerular filtration rate; HCB; Hexachlorobenzene; HDL; High density lipoprotein; IVS; Inter ventricular septum; LDL; Low density lipoprotein; LVEDD; Left vent
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: 1°BAs; primary bile acids; 2°BAs; secondary bile acids; BA; bile acid; CDCA; chenodeoxycholic acid; CA; cholic acid; DEX; dexamethasone; GR; glucocorticoid receptor; MCA; muricholic acid; PXR; pregnaneâXâreceptor; ΣBAs; total bile acids; T-BAs; tau
Keywords: 11βHSD; 11β-Hydroxysteroid dehydrogenase; ABC; ATP-binding cassette; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; BCRP; breast cancer resistance protein; CAR; constitutive androstane receptor; CYP; cytochrome P45
Keywords: AHR; aryl hydrocarbon receptor; ALD; alcoholic liver disease; BAs; bile acids; CAR; constitutive androstane receptor; CARM1; coactivator associated arginine methyltransferases 1; CBP/P300; CREB-binding protein/p300; CYP27A1/Cyp27a1; sterol 27α-hydroxylas
Keywords: AHR; aryl hydrocarbon receptor; AR; androgen receptor; As; arsenic; BaP; benzo[a]pyrene; CASP; caspase; CRISPR; clustered regularly interspaced short palindromic repeats; CTD; Comparative Toxicogenomics Database; CYP; cytochrome P450; CXCL8; chemokine (C-
Keywords: HUVEC; AhR; Nrf2; PXR; Simvastatin;
Keywords: AD; Alzheimer's disease; EEG; electroencephalographic; EPM; Elevated-Plus Maze; NPR; novel place recognition; NR; Nuclear receptor; PXR; pregnane xenobiotic receptor; TJ; tight junction; nuclear receptor PXR; anxiety; recognition memory; EEG; neurovascu
Keywords: ASBT; apical sodium-dependent bile acid transporter; ASDs; amorphous solid dispersions; BACS; bile acid-CoA synthase; BAT; bile acid-amino acid transferase; BCS; biopharmaceutics classification system; BSH; bile salt hydrolase; C4; 7α-hydroxy-4-cholesten
Keywords: Oxysterols; Cancer; Polymorphism; Risk; Genetics; Cholesterol; 25(OH)D; 25-hydroxyvitamin D; ABC; ATP-binding cassette; AEBS; antiestrogen-binding site; BC; breast cancer; BCR; biochemical recurrence; CETP; cholesteryl ester transfer protein; CH25H; chole
Keywords: Cytochrome P450; Liver; Gene expression; Sex; Age; Drug metabolism; BChE; butyrylcholinesterase; CYP; cytochrome P450; GST; glutathione S-transferase; PCR; polymerase chain reaction; PXR; pregnane X receptor; RT-PCR; reverse transcriptase PCR; SULT; sulfo
Keywords: PXR; Pregnane X receptor; LPS; Lipopolysaccharide; TLR4; Toll-like receptor 4; DMETs; Drug metabolizing enzymes and transporters; CES; Carboxylesterase; CYP; Cytochrome P450; SN-38; 7-Ethyl-10-hydroxycamptothecin; SN-38G; SN-38 glucuronide; UGT1A1; Uridin
Keywords: Hepatic injury; Flavonoids; Hepatoprotection; Mechanisms; Traditional Chinese medicinal (TCM) herbs; ATGL; adipose triglyceride lipase; D-GaIN; d-galactosamine; FLIP; FLICE inhibitory protein; HA; hyaluronic acid; LDH; lactate dehydrogenase; LDL-C; low-de
Keywords: Benchmark dose modeling; DNA methylation; LINE-1; miRNA; Metabolomics; Hepatotoxicants; Dose-response; Ahr; Aryl Hydrocarbon receptor; BA; Bile Acid; BMD; Benchmark Dose; BrdU; Bromodeoxyuridine; CAR; Constitutive Androgen Receptor; CF; Clofibrate; ChIP;
Keywords: transporters; metabolism; drug-metabolizing enzymes; pharmacokinetics; hepatic transport; hepatic metabolism; organic anion-transporting polypeptide transporters; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATP; adenosine triphosphate;
Keywords: ADMET; absorption, distribution, metabolism, excretion, toxicity; AHR; aryl hydrocarbon receptor; AUC; area under the curve; BVU; (E)-5-(2-bromovinyl) uracil; CAR; constitutive androstane receptor; cMOAT; Canalicular multispecific organic anion transporte
Keywords: Intracellular drug concentration; Pharmacodynamics; OCT; MATE; PMAT; Drug transporter; ABC; ATP-binding cassette; ACC; acetyl-CoA carboxylase; AMP; adenosine monophosphate; AMPK; AMP-activated protein kinase; AUC; area under the concentration time curve;
Keywords: ABCB; ATP-binding cassette sub-family B; Apo; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BDL; bile duct ligation; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; C/EBP; CCAAT-enhancer-binding protein; C
Keywords: PXR; Polycrystal; X-ray; Nanodiamond; Texture;
Keywords: Ciona intestinalis; Botryllus schlosseri; Pregnane X receptor; Saccharomyces cerevisiae; Marine biotoxins; Bioassay; AD; activation domain; AF-2; transcription activation function domain; BsVDR/PXRα; Botryllus schlosseri VDR/PXR orthologue α; BPA; bisph
Keywords: AR; androgen receptor; CAR; constitutive androstane receptor; DBD; DNA-binding domain; EDC; endocrine disrupting chemical; ER; estrogen receptor; FXR; farnesoid X receptor; GR; glucocorticoid receptor; HRE; hormone responsive elements; LBD; ligand-binding
Keywords: CYP; cytochrome P-450; GSH-transferase; glutathione-S-transferase; UDP-glucuronosyltransferase; uridine 5â²-diphospho-glucuronosyltransferase; EGb761®; Ginkgo biloba extract, CAS 122933-57-7; AhR; aryl hydrocarbon receptor; PXR; pregnane X receptor; CAR
Keywords: LPS; lipopolysaccharide; IL-6; interleukin-6; DMEs; drug-metabolizing enzymes; Ces (mouse) or CES (human); carboxylesterases; CYP; cytochrome P450; PXR; pregnane X receptor; CAR; constitutive androstane receptor; RXR; retinoid X receptor; NFκB; nuclear f
Keywords: AhR; aryl hydrocarbon receptor; ARE; antioxidant response element; BT; black tea; CYP; cytochrome P450; DME; drug-metabolizing enzymes; DR4; direct repeat with 4Â bp spacer; DRE; dioxin response elements; GT; green tea beverage; EC; epicatechin; EGC; epig
Keywords: BTBPE; 1,2-bis(2,4,6-tribromophenoxy)ethane; EDC; endocrine disrupting chemicals; HBCD; hexabromocyclododecane; HPT; hypothalamus-pituitary-thyroid; ID, ID1, ID2, ID3; iodothyronine deiodinase, type 1, type 2, type 3; mono; monodeiodination; OH-PBDE;
Keywords: ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: Rilpivirine; Drug interaction; CYP; Drug transporter; PXR;
Keywords: Cholesterol; Oxysterol; CYP46A1; CYP27A1; CYP3A4; CYP39A1; CYP7B1; CH25H; Cholesterol 7α-hydroxylase; Sterol 27-hydroxylase; Cholesterol 24-hydroxylase; Cholesterol 25-hydroxylase; Oxysterol 7α-hydroxylase; 24-hydroxycholesterol 7α-hydroxylase; Epigene
Keywords: MS; mass spectrometry; UPLC; ultraperformance liquid chromatography; UPLC-ESI-QTOFMS; UPLC-electrospray ionization-quadrupole time-of-flight MS; LCMS; liquid chromatography-mass spectrometry; GCMS; gas chromatography-mass spectrometry; NMR; nuclea
Keywords: BH; Bcl-2 homology; CA; cholic acid (3α,7α,12α-trihydroxy-5β-cholanoic acid); CDCA; chenodeoxycholic acid (3α,7α-dihydroxy-5β-cholanoic acid); DCA; deoxycholic acid (3α,12α-dihydroxy-5β-cholanoic acid); EGFR; epidermal growth factor receptor; ER
PXR as a mediator of herb-drug interaction
Keywords: Drug metabolism; Herb-drug interaction; PXR; St. John's Wort; Xenobiotics;
A CYP2B6-humanized mouse model and its potential applications
Keywords: CYP2B6; Liver; Drug metabolism; Xenobiotic toxicity; Knockout mice; Humanized mice; WT; wild-type; CYPs; cytochromes P450; CAR; constitutive androstane receptor; PXR; pregnane X receptor; GR; glucocorticoid receptor; PB; phenobarbital; and DEX; dexamethas
Amelioration of PXR-mediated CYP3A4 induction by mGluR2 modulators
Keywords: mGluR2; PXR; X-ray; CYP3A4/5 induction;
Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes
Keywords: AhR; aryl hydrocarbon receptor; AP1; activating protein 1; ARE; antioxidant-response element; CAR; constitutive androstane receptor; CYP; cytochrome P450; DREs; dioxin-responsive elements; EMSA; electromobility gel shift assay; FBS; fetal bovine serum; GS
Response of the nuclear receptors PXR and CAR and their target gene mRNA expression in female piglets exposed to zearalenone
Keywords: Piglet; CAR; PXR; Zearalenone; Signal pathway;
Response of PXR signaling pathway to simvastatin exposure in mosquitofish (Gambusia affinis) and its histological changes
Keywords: Simvastatin; Mosquito fish; PXR; Transcriptional expression; Enzyme activity; Morphological changes;
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
Keywords: ROR; retinoic acid-related orphan receptor; PXR; pregnane X receptor; LXR; liver X receptor; IBD; inflammatory bowel disease; RA; rheumatoid arthritis; MS; multiple sclerosis;
Essential oils of culinary herbs and spices activate PXR and induce CYP3A4 in human intestinal and hepatic in vitro models
Keywords: AhR; aryl hydrocarbon receptor; EO; essential oil; EtOH; ethanol; CAR; constitutive androstane receptor; GR; glucocorticoid receptor; PXR; pregnane X receptor; RIF; rifampicin; VDR; vitamin D receptor; Food-drug interactions; Human hepatocytes; Essential
Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics
Keywords: ABC; ATP-binding cassette transporter; ADAR; adenosine deaminase acting on RNA; ADH; alcohol dehydrogenase; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; ALS; amyotrophic lateral sclerosis; AZIN1; antizyme inhibitor 1; AMPA; α-amino-3-hydroxy
Liver lobe and strain differences in the activity of murine cytochrome P450 enzymes
Keywords: Mouse; Cytochrome P450; Liver microsomes; Liver lobe differences; AhR; aryl hydrocarbon receptor; Alas1; delta-aminolevulinate synthase 1; BCA; bicinchoninic acid; BSA; bovine serum albumin; CAR; constitutive androstane receptor; CPR; cytochrome P450 redu
PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ
Keywords: Thyroid hormones; Scaffold protein; PDZ-domain; Gene regulation; Thyroid hormone receptors; 5-HT2A; Serotonin 2A receptor; ABC; ATP-binding cassette transporter; AhR; Transcription factor aryl hydrocarbon receptor; BCRP; Breast cancer resistance protein;
Regulation of pregnane-X-receptor and microRNAs on detoxification-related genes expressions in Mugilogobius abei under the exposure to diclofenac
Keywords: Diclofenac; Mugilogobius abei; pxr; microRNAs; Detoxification;
Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive
Keywords: AA-EQS; average annual environmental quality standard; ACR; acute-to-chronic ratio; AhR; arylhydrocarbon receptor; AR; androgen receptor; AWTP; advanced water treatment plant; BEQ; bioanalytical equivalent concentration; DWTP; drinking water treatment pla
From TCDD-mediated toxicity to searches of physiologic AHR functions
Keywords: AHR; aryl hydrocarbon receptor; CAR; constitutive androstane receptor; PXR; pregnane-X-receptor; CYP; cytochrome P450; IDO1; indoleamine-2,3-dioxygenase; UDP; UDP-glucuronosyltransferase; FICZ; 6-formylindolo[3,2-b]carbazole; ICZ; indolo[3,2-b]carbazole;
Ubiquitination/sumoylation: An alternative pathway to modify gene regulation directed by xenosensors
Keywords: Epigenetic regulation; Post-translational modifications; Nuclear receptors; Xenobiotics metabolism; AHR; aryl hydrocarbon receptor; AHRR; aryl hydrocarbon receptor repressor; ARNT; aryl hydrocarbon receptor nuclear translocator; CAR; constitutive androsta
Integrating extended focused assessment with sonography for trauma (eFAST) in the initial assessment of severe trauma: Impact on the management of 756 patients
Keywords: CXR; chest x-ray; PXR; pelvic x-ray; FAST; focused assessment with sonography for trauma; WBCT; whole-body computed tomography; LUS; lung ultrasonography; eFAST; extended focused assessment with sonography for trauma FAST; GCS; Glasgow Coma Scale; AIS; Ab
Combination of CYP2C19 genotype with non-genetic factors evoking phenoconversion improves phenotype prediction
Keywords: CAR; constitutive androstane receptor; CI; confidence interval; CYP; cytochrome P450; EM; extensive metabolizer; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GR; glucocorticoid receptor; IM; intermediate metabolizer; PCR; polymerase chain reaction; PM
Effect of amyloid beta on ATP-binding cassette transporter expression and activity in porcine brain microvascular endothelial cells
Keywords: ABCB1; ABCG2; ABCC5; Nuclear receptors; Amyloid-β; Alzheimer's disease; Porcine brain endothelial cells; ABC; ATP-binding cassette; Aβ(1-42); amyloid-β (1-42); BBB; blood-brain barrier; CAR; constitutive androstane receptor; CAPS; 3-(Cyclohexylam
Characterization of CYP2C Induction in Cryopreserved Human Hepatocytes and Its Application in the Prediction of the Clinical Consequences of the Induction
Keywords: cytochrome P450; mathematical models; hepatocytes; drug-drug interaction; induction; CAR; constitutive androstane receptor; CITIO; 6-(4-clorophenyl) imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime; P450; cytochrome P450; DDI; drug-d
Nuclear receptor FXR, bile acids and liver damage: Introducing the progressive familial intrahepatic cholestasis with FXR mutations
Keywords: NR; nuclear receptor; FXR; farnesoid X receptor; RXR; retinoid X receptor; PXR; pregnane X receptor; VDR; Vitamin D receptor; TGR5; G protein-coupled bile acid receptor; Lrh1; liver receptor homolog 1; Mdr; multidrug resistance protein; Abcb4; ATP Bindi
Epidermal Overexpression of Xenobiotic Receptor PXR Impairs the Epidermal Barrier and Triggers Th2 Immune Response
Keywords: AD; atopic dermatitis; CYP450; cytochrome P450; DC; dendritic cell; ILC; innate lymphoid cell; ILCs2; type 2 innate lymphoid cells; K14; keratin 14; PXR; pregnane X receptor; TEWL; transepidermal water loss; Th; T helper; TSLP; thymic stromal lymphopoiete