دانلود مقالات ISI درباره Pxr + ترجمه فارسی

E4bp4 regulates carboxylesterase 2 enzymes through repression of the nuclear receptor Rev-erbα in mice

Keywords: bZip; the basic leucine zipper; CAR; constitutive androstane receptor; Ces/CES; mouse and human carboxylesterases; ChIP; chromatin immunoprecipitation assay; Co-IP; co-immunoprecipitation; CYP7A1; cholesterol 7alpha-hydroxylase; DMEM; Dulbecco's modifie

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

In vitro effect of mPEG2k-PCLx micelles on rat liver cytochrome P450 enzymes

Keywords: Ahr; aryl hydrocarbon receptor; Car; constitutive androstane receptor; Pxr; pregnane X receptor; mPEG2k-PCLx micelles; Cytochrome P450 enzymes; Inhibition; Induction; Rat liver microsomes; Primary rat hepatocytes;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Biotechnology Challenges to In Vitro Maturation of Hepatic Stem Cells

Keywords: Liver Development; Differentiation; Hepatocyte; Culture; CRISPR; clustered regularly interspaced short palindromic repeats; CYP; cytochrome P450; 3D; 3-dimensional; DNMTi; DNA methylation inhibitor; ECM; extracellular matrix; ESC; embryonic stem cell; ES-

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

PXR: Structure-specific activation by hepatotoxic pyrrolizidine alkaloids

Keywords: Pyrrolizidine alkaloids; Nuclear receptors; PXR; Echimidine;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Human-based systems: Mechanistic NASH modelling just around the corner?

Keywords: Elafibranor (PubChem CID: 9864881); Obeticholic acid (PubChem CID: 447715); Pioglitazone (PubChem CID: 4829); Rosiglitazone (PubChem CID: 77999); Fenofibrate (PubChem CID: 3339); Serine (PubChem CID: 5951); ACC1; acetyl-coenzyme A carboxylase 1; AdipoR; a

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Proteomics and phosphoproteomics analysis of liver in male rats exposed to bisphenol A: Mechanism of hepatotoxicity and biomarker discovery

Keywords: Bisphenol A; Proteomics; Phosphoproteomics; Hepatotoxicity; Oxidative stress; 2-DE; Two-dimensional gel electrophoresis; AKR1D1; Aldo-keto reductase family 1 member D1; BHMT; betaine homocysteine s-methyltransferase; BPA; Bisphenol A; Cat; catalase; CYP;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of nuclear receptor PXR impairs glucose tolerance and dysregulates GLUT2 expression and subcellular localization in liver

Keywords: PXR; GLUT2; GCK; Impaired glucose tolerance; Diabetes;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Disruption of TFGβ-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand

Keywords: CDCA; chenodeoxycholic acid; CA; cholic acid; DCA; deoxycholic acid; LCA; litocholic acid; BAs; bile acids; BARS; bile acid activated receptors; GPBAR1; G protein coupled bile acid receptor; TGR5; Takeda G protein receptor 5; FXR; farnesoid x-receptor; PX

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice

Keywords: Food safety; Feed additives; Ethoxyquin; Hepatotoxicity; Benchmark dose; Multi-level omics; ADI; Acceptable Daily Intake; AIC; Akaike Information Criterion; ALT; Alanine transferase; AST; Aspartate transferase; BMD; Benchmark dose; BMDL; Lower bound bench

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR

Keywords: Natural products; Nuclear receptors; Liver X receptor; Farnesoid X receptor; Retinoid X receptor; Metabolic syndrome; Precision medicine; 6-ECDCA; 6α-ethyl-chenodeoxycholic acid (obeticholic acid); AA; arachidonic acid; ABC; ATP-binding cassette transpor

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

Alisol B 23-acetate from the rhizomes of Alisma orientale is a natural agonist of the human pregnane X receptor

Keywords: Alisol B 23-acetate; Alisma orientale; Pregnane X receptor; Alisma rhizome; Nuclear receptor; CYP3A4; cytochrome P450 3A4; DMEs; drug metabolizing enzymes; HPH; human primary hepatocyte; ABA; alisol B 23-acetate; PXR; pregnane X receptor; SRC-1; steroid r

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnane X receptor (PXR) signaling in seabream primary hepatocytes exposed to extracts of seawater samples collected from polycyclic aromatic hydrocarbons (PAHs)-contaminated coastal areas

Keywords: Nuclear receptor; PXR; CYP3A; LXR; Polycyclic aromatic hydrocarbons; Gene transcription; Endocrine disruption; Adriatic sea;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

From dioxin toxicity to putative physiologic functions of the human Ah receptor in homeostasis of stem/progenitor cells

Keywords: AhR; aryl hydrocarbon receptor; PXR; pregnane-X-receptor; CYP; cytochrome P450; UGT; UDP-glucuronosyltranswferase; FICZ; 6-formylindolo[3,2-b]carbazole; ICZ; indolo[3,2-b]carbazole; ITE; 2-(1H--indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of γ-hydroxybutyrate (GHB) binding

Keywords: Cytochrome P-450 (CYP); Microsomal CYPs; PXR; Xenobiotic receptor induction; Cytotoxicity; Mitochondrial function; Apoptosis; HepG2 cells; Primary human hepatocytes; Gene expression;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Intracellular localization of pregnane X receptor in HepG2 cells cultured by the hanging drop method

Keywords: Pregnane X receptor; Three-dimensional culture; Hanging drop method; Cytoplasmic retention; Nuclear translocation; Human hepatocarcinoma cell; 2D; two-dimensionally; 3D; three-dimensionally; CAR; constitutive androstane receptor; CCRP; cytoplasmic CAR ret

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnenolone 16α-carbonitrile ameliorates concanavalin A-induced liver injury in mice independent of the nuclear receptor PXR activation

Keywords: PXR; pregnane X receptor; PCN; pregnenolone 16α-carbonitrile; Con A; concanavalin A; DSS; dextran sulfate sodium; TNF; tumor necrosis factor; LPS; lipopolysaccharide; NF-κB; nuclear factor κB; MPO; myeloperoxidase; SOCS1; suppressor of cytokine signali

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Heterodimerization of Retinoid X Receptor with Xenobiotic Receptor partners occurs in the cytoplasmic compartment: Mechanistic insights of events in living cells

Keywords: Nuclear receptors; Heterodimerization; RXR; PXR; CAR; Nuclear localization signal;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

RNA sequencing indicates that atrazine induces multiple detoxification genes in Daphnia magna and this is a potential source of its mixture interactions with other chemicals

Keywords: Gene expression; Mixture model; Nuclear receptor; Aquatic toxicology; Induction; Concentration-dependent; ADH; Alcohol dehydrogenase; AUC; Area under the curve; ABC transporter; ATP-binding cassette transporter; BPA; Bisphenol A; CATAM; Computational Appr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Relationship between NR1I2 polymorphisms and inflammatory bowel disease risk: A systematic review and meta-analysis

Keywords: NR1I2; Homo sapiens nuclear receptor subfamily 1 group I member 2; IBD; inflammatory bowel diseases; UC; Ulcerative Colitis; CD; Crohn's Disease; OR; odd radio; CI; confidence interval; PPARα; peroxisome proliferator-activated receptor alpha; FXR; farnes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage

Keywords: PXR; pregnane X receptor; AhR; aryl hydrocarbon receptor; DRE; dioxin response element; BaP; benzo[a]pyrene; RIF; rifampicin; H2Ax; histone 2Ax; CAR; constitutive androstane receptor; FXR; farnesoid X receptor; CYP450; cytochrome P450; EROD; 7-ethoxyresor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Profiling of bisphenol S towards nuclear receptors activities in human reporter cell lines

Keywords: GR; PXR; AHR; VDR; AR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Itraconazole cis-diastereoisomers activate aryl hydrocarbon receptor AhR and pregnane X receptor PXR and induce CYP1A1 in human cell lines and human hepatocytes

Keywords: AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; CYP; cytochrome P450; DRE; dioxin responsive element; DMEM; Dulbecco modified Eagle medium; DMSO; dimethylsulfoxide; EMSA; electrophoretic mobility shift assay; EROD; 7-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Pregnane X receptor (PXR) deficiency improves high fat diet-induced obesity via induction of fibroblast growth factor 15 (FGF15) expression

Keywords: FGF; fibroblast growth factor; PXR; pregnane X receptor; NR; nuclear receptor; CAR; constitutive androstane receptor; CYP; cytochrome P450; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; sterol 12α-hydroxylase; HFD; high fat diet; KO; knockout; ob; obesity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor

Keywords: BA; bile acid; CA; cholic acid; CDCA; chenodeoxycholic acid; CYP; cytochrome P450; DCA; deoxycholic acid; 6-ECDCA; 6α-ethyl-chenodeoxycholic acid, obeticholic acid; FXR; farnesoid X receptor; LBD; ligand binding domain; LCA; lithocholic acid; PXR; pregna

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

A combination of dietary N-3 fatty acids and a cyclooxygenase-1 inhibitor attenuates nonalcoholic fatty liver disease in mice

Keywords: Nonalcoholic fatty liver disease; Fish oil; Omega-3 fatty acids; PXR; Bile;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Xenobiotics and the Glucocorticoid Receptor

Keywords: GC; Glucocorticoids; GR; Glucocorticoid Receptor; NR; Nuclear receptor; PXR; Pregnane X receptor; CAR; Constituitive androstane receptor; SCN; Supra-chiasmic nucleus; CBG; Corticosteroid binding globulin; HSD; Hydroxysteroid dehydrogenase; MR; Minerocorti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Treatment of estrogen-dependent diseases: Design, synthesis and profiling of a selective 17β-HSD1 inhibitor with sub-nanomolar IC50 for a proof-of-principle study

Keywords: 17β-Hydroxysteroid dehydrogenase type 1; Enzyme inhibitor; Steroidogenic enzymes; Estrogen-dependent disease; Intracrinology; (h)17β-HSD1; (human) 17β-hydroxysteroid dehydrogenase type 1; (h)17β-HSD2; (human) 17β-hydroxysteroid dehydrogenase type 2;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor

Keywords: DR; direct repeat; EMSA; electrophoretic mobility shift assay; ER; everted repeat; LXR; liver X receptor; PXR; pregnane X receptor; RXR; retinoid X receptor; SMPDL; sphingomyelin phosphodiesterase acid-like; Rifampin (PubChem CID: 6243627); GW3965 hydroch

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Vitamin K and osteoporosis: Myth or reality?

Keywords: VK; Vitamin K; OC; Osteocalcin; RCTs; Randomized Control Trials; BMD; Bone Mineral Density; BTM; Bone Turnover Markers; VD; Vitamin D; Gla; γ-carboxyglutamic acid; PT; Prothrombin Time; MGP; Matrix Gla Protein; Gas-6; Growth arrest-specific 6 protein; uc

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Cellular adaptation to xenobiotics: Interplay between xenosensors, reactive oxygen species and FOXO transcription factors

Keywords: AhR; arylhydrocarbon receptor; AIP; AhR interacting protein; ARE; antioxidant response element; ARNT; AhR nuclear translocator; bHLH; basic helix-loop-helix (DNA binding and dimerisation domain); CAR; constitutive androstane receptor; CBP; CREB-binding pr

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

In Silico Prediction of hPXR Activators Using Structure-Based Pharmacophore Modeling

Keywords: PXR; cytochrome P450; computational ADME; induction; in silico modeling; molecular modeling;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells

Keywords: ADH; Alcohol dehydrogenase; AHR; Aryl hydrocarbon receptor; ALD; Alcohol liver disease; ARNT; AHR nuclear translocator; CAR; Constitutive androstane receptor; CYP; Cytochrome P450; ER; Estrogen receptor; OCP; Organochlorine pesticide; POP; Persistent orga

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Rifampicin-induced injury in HepG2 cells is alleviated by TUDCA via increasing bile acid transporters expression and enhancing the Nrf2-mediated adaptive response

Keywords: RFP; rifampicin; TUDCA; tauroursodeoxycholic acid; Nrf2; nuclear factor erythroid 2-related factor; DILI; drug-induced liver injury; ALF; acute liver failure; TB; tuberculosis; INH; isoniazid; GSH; glutathione; BAs; bile acids; ER; endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of hepatic abcb4 and cyp3a65 gene expression and multidrug/multixenobiotic resistance (MDR/MXR) functional activity in the model teleost, Danio rerio (zebrafish)

Keywords: ABC; ATP-binding cassette; CYP; cytochrome P450; KTC; ketoconazole; MDR/MXR; multidrug/multixenobiotic resistance; P-gp; P-glycoprotein; PCN; pregnenolone 16α-carbonitrile; PXR; pregnane X-receptor; ARmax; maximum accumulation rate; Cmax; maximum concent

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

Keywords: Regulatory toxicology; Transcriptomics; Metabolomics; Good laboratory practice (GLP); Weight-of-evidence (WoE); Adverse outcome pathway (AOP); Mode-of-action (MoA); Gene expression; Differentially expressed genes; ANOVA; Analysis of variance; AOP; Adverse

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

RNAi suppression of nuclear receptor genes results in increased susceptibility to sulfoxaflor in brown planthopper, Nilaparvata lugens

Keywords: AHR; aryl hydrocarbon receptor; BLAST; basic local alignment search tool; CAR; constitutive androstane receptor; CYP; cytochrome P450; DBD; DNA-binding domain; ERR; estrogen-related receptor; EST; expressed sequence tag; GR; glucocorticoid receptor; HNF4;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal

Keywords: CAR; constitutive androstane receptor; CDK2; cyclin-dependent kinase 2; ChIP assay; chromatin immunoprecipitation assay; CYP; cytochrome P450; FOXO1; forkhead box protein O1; PCK1; phosphoenolpyruvate carboxykinase 1; PPARα; peroxisome proliferator-activ

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells

Keywords: Human iPS cells; Enterocyte-like cells; CYP3A4 induction; Nuclear receptor; CDX2; caudal type homeobox 2; CYP3A4; cytochrome P450 3A4; DEX; dexamethasone; EGF; epidermal growth factor; FGF2; fibroblast growth factor 2; FXR; farnesoid X receptor; GR; gluco

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Bortezomib and ixazomib protect firefly luciferase from degradation and can flaw respective reporter gene assays

Keywords: Bortezomib; Carfilzomib; Firefly luciferase; Inhibition; Ixazomib; Reporter gene assay; PXR; pregnane-X-receptor; RT-qPCR; reverse transcription-quantitative polymerase chain reaction; DMSO; dimethyl sulfoxide; PBS; phosphate-buffered saline; BSA; bov

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewInfluence of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on expression of P-glycoprotein and cytochrome P450 3A in sheep

Keywords: P-gp,MDR1,ABCB1; P-glycoprotein; CYP3A4; cytochrome P450 3A; VDR; vitamin D receptor; PXR; pregnane X receptor; RXR; αretinoid X receptor; BW; body weight; 25-OHD3; 25-hydroxyvitamin D3; 1,25-(OH)2D3; 1,25-dihydroxyvitamin D3; Cholecalciferol; Ruminant;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Indirubin, a component of Ban-Lan-Gen, activates CYP3A4 gene transcription through the human pregnane X receptor

Keywords: AhR activator; Indirubin; CYP3A4 induction; PXR; Herb-drug interactions; AdCont; β-galactosidase-expressing adenovirus; AdPXR; human PXR-expressing adenovirus; AdhPXR-shRNA; AdhPXR-short hairpin RNA; AhR; aryl hydrocarbon receptor; Ct; threshold PCR cy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Tryptophan 299 is a conserved residue of human pregnane X receptor critical for the functional consequence of ligand binding

Keywords: PXR; CYP3A4; Xenobiotic receptor; SAR; Transcriptional regulation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

New brominated flame retardants and their metabolites as activators of the pregnane X receptor

Keywords: CYP; cytochrome P450; PCR; polymerase chain reaction; PPAR; peroxisome proliferator activated receptor; PXR; pregnane X receptor; TBB; 2-ethylhexyl 2,3,4,5-tetrabromobenzoate; TBPH; bis(2-ethylhexyl) tetrabromophthalate; TBBA; 2,3,4,5-tetrabromobenzoic ac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes

Keywords: CYP; cytochrome P450; miRNA; microRNA; DMETs; drug metabolizing enzymes and transporters; CAR; constitutive androstane receptor; PXR; pregnane X receptor; RE; response element; 3′-UTR; 3′-untranslated region; SULT; sulfotransferase; Ago; argonaute RIS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

RXRα, PXR and CAR xenobiotic receptors mediate the apoptotic and neurotoxic actions of nonylphenol in mouse hippocampal cells

Keywords: bbb; blood-brain barrier; CAR; constitutive androstane receptor; DIV; day in vitro; DMSO; dimethyl sulfoxide; EDC; endocrine-disrupting chemical; ER; estrogen receptor; LDH; lactate dehydrogenase; NP; nonylphenol; PBS; phosphate-buffered saline; PXR; pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4

Keywords: FLU; flutamide; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; CYP; cytochrome P450; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; 3-MC; 3-methylcholanthrene; ABCC4; ATP-binding cassette sub-family C member 4; MRP4; mul

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Functional induction of P-glycoprotein efflux pump by phenyl benzenesulfonamides: Synthesis and biological evaluation of T0901317 analogs

Keywords: T0901317; Benzene sulfonamides; PXR; LS180; P-gp induction; Alzheimer’s disease

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Insights into CYP2B6-mediated drug-drug interactions

Keywords: CAR; constitutive androstane receptor; C/EBP; CCAAT/enhancer-binding protein; CHOP; cyclophosphamide-doxorubicin-vincristine-prednisone; CITCO; (6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime); COUP-TF; chic

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450

Keywords: AhR; Aryl Hydrocarbon Receptor; CCBs; calcium channel blockers; CYP; cytochrome P450; DEX; dexamethasone; DMSO; dimethysulfoxide; GR; Glucocorticoid Receptor; HLMs; human liver microsomes; PXR; pregnane X receptor; RIF; rifampicin; TCDD; 2,3,7,8 tetrachlo

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Involvement of pregnane X receptor in the impaired glucose utilization induced by atorvastatin in hepatocytes

Keywords: HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; PCN; pregnenolone-16α-carbonitrile; PXR; pregnane X receptor; GLUT2; glucose transporter 2; GCK; glucokinase; PDK2; pyruvate dehydrogenase kinase isoenzyme 2; PEPCK1; phosphoenolpyruvate carboxykinase 1; G6

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه