Keywords: پییررولوپیریمیدین; Interleukin 17 secretion; Interleukin 5; Pyrrolopyrimidine; Thienopyrimidine; Furopyrimidine;
مقالات ISI پییررولوپیریمیدین (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors
Keywords: پییررولوپیریمیدین; Antiviral drugs; HCV; Molecular modeling; NS5B polymerase; Pyrrolopyrimidine
Balancing potency, metabolic stability and permeability in pyrrolopyrimidine-based EGFR inhibitors
Keywords: پییررولوپیریمیدین; EGFR; Pyrrolopyrimidine; SAR; ADME; Metabolism; Erlotinib;
Novel type of plasmin inhibitors: Providing insight into P4 moiety and alternative scaffold to pyrrolopyrimidine
Keywords: پییررولوپیریمیدین; MMP; matrix metalloproteinase; UK; urokinase; pNA; para-nitroanilide; MCA; 7-amino-4-methyl-coumarin amide; Boc; t-butoxycarbonyl; Pyr; pyroglutamic acid; Plasmin inhibitors; Benzimidazole; Scaffold; Pyrrolopyrimidine; P4 moiety; Structure-activity rela
Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines as highly potent EGFR-TK inhibitors with Src-family activity
Keywords: پییررولوپیریمیدین; Pyrrolopyrimidine; EGFR-TK; Src-kinase; Cancer; CSF1R kinase; ErlotinibBenzylamine (PubChem CID: 7504); 1-Phenylethanamin (PubChem CID: 7408); PKI-166 (PubChem CID: 6918403); 2-Amino-2-phenylethan-1-ol (PubChem CID: 92466); 2-Methoxyphenylboronic acid (Pu
Pyrrolopyrimidine-inhibitors with hydantoin moiety as spacer can explore P4/S4 interaction on plasmin
Keywords: پییررولوپیریمیدین; MMP; matrix metalloproteinase; PK; plasma kallikreine; UK; urokinase; DABCO; 1,4-diazabicyclo[2.2.2]octane; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; DKP; diketopiperazine; <Glu; pyroglutamic acid; Plasmin inhibitors; P4 moiety; Scaffold; Pyrrolopyrimidine
Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors
Keywords: پییررولوپیریمیدین; Tie-2; Kinase inhibitor; Pyrrolopyrimidine; Angiogenesis; Cancer;
Selectivity between N-1 and N-7 nucleosides: regioselective synthesis of BMK-Y101, a potent cdk7 and 9 inhibitor
Keywords: پییررولوپیریمیدین; Nucleosides; Cdk inhibitor; Regioselective; Pyrrolopyrimidine; Glycosylation;
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: Development of inhibitors with broad spectrum, Gram-negative antibacterial activity
Keywords: پییررولوپیریمیدین; Bacterial topoisomerases; Pyrrolopyrimidine; GyrB; ParE; Gram-negative antibacterial agents; Inhibitor;
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity
Keywords: پییررولوپیریمیدین; Bacterial topoisomerases; GyrB; ParE; Pyrrolopyrimidine; Inhibitor;
Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors
Keywords: پییررولوپیریمیدین; Aurora kinase; Cyclin dependent kinase; Cell cycle arrest; Pyrrolopyrimidine; Cytotoxicity;
Activity of 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines to Tetrahymena
Keywords: پییررولوپیریمیدین; Pyrrolopyrimidine; Antiprotozoal agent; Tetrahymena; Kinase; Benzylamine
Discovery and hit-to-lead optimization of pyrrolopyrimidines as potent, state-dependent Nav1.7 antagonists
Keywords: پییررولوپیریمیدین; Nav1.7; Voltage-gated sodium channels; Nav channels; Sodium channel blockers; Sodium channel inhibitors; Sodium channel antagonists; Congenital indifference to pain; Paroxysmal extreme pain disorder; Primary erythromelalgia; Pyrrolopyrimidine;
Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone
Keywords: پییررولوپیریمیدین; Hsp90 inhibitor; Structure-based design technique; Pyrrolopyrimidine
Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines
Keywords: پییررولوپیریمیدین; Pyrrolopyrimidine; Tyrosine kinase; ErbB1; Pyrroles; 4-Chloropyrolopyrimidines; Cancer
Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity
Keywords: پییررولوپیریمیدین; IGF-1R; IGF-IR; JNK; Pyrrolopyrimidine
Optimization of a series of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine inhibitors of IGF-1R: Elimination of an acid-mediated decomposition pathway
Keywords: پییررولوپیریمیدین; IGF-1R; Pyrrolopyrimidine; IGF-IR; Kinase
Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase
Keywords: پییررولوپیریمیدین; Pyrrolopyrimidine; IGF-1R; Kinase inhibitor; IGF-IR
Discovery of selective and nonpeptidic cathepsin S inhibitors
Keywords: پییررولوپیریمیدین; Cathepsin S inhibitor; Pyrrolopyrimidine; Nitrile; Nonpeptidic; Cysteine protease
Synthesis and structure based optimization of novel Akt inhibitors
Keywords: پییررولوپیریمیدین; Akt; Pyrrolopyrimidine; Spiroindoline; Imidazopiperidine
An expedient microwave-assisted, solvent-free, solid-supported synthesis of pyrrolo[2,3-d]pyrimidine-pyrano[5,6-c]coumarin/[6,5-c]chromone derivatives by intramolecular hetero Diels-Alder reaction
Keywords: پییررولوپیریمیدین; Hetero Diels-Alder; Pyrrolopyrimidine; Pyranocoumarin; Microwave;
Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)
Keywords: پییررولوپیریمیدین; JAK3; Janus Kinase; Tyrosine kinases; Cytokines; Pyrrolopyrimidine
Novel scaffold for cathepsin K inhibitors
Keywords: پییررولوپیریمیدین; Cathepsin K inhibitors; Pyrrolopyrimidine; Novel scaffold
New pyrrolopyrimidin-6-yl benzenesulfonamides: Potent A2B adenosine receptor antagonists
Keywords: پییررولوپیریمیدین; A2B adenosine receptor antagonists; Asthma; Pyrrolopyrimidine; Sulfonamides